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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T10506 | PPAR agonist 1 | PPAR | |
PPAR agonist 1 is an agonist of PPAR α/γ, used for reducing blood glucose, lipid levels, reducing body weight, and lowering cholesterol. | |||
T39516 | Bocidelpar | PPAR | |
Bocidelpar is a modulator of PPARδ with an EC50 of 7.80 nM and improves mitochondrial biogenesis and function in Duchenne Muscular Dystrophy muscle cells. | |||
TN1693 | Glabrone | Influenza Virus , PPAR | |
Glabrone shows antiviral activity against influenza virus. | |||
T22708 | Darglitazone | CP-86325 | PPAR |
Darglitazone (CP-86325) is a potent, selective agonist of PPAR-γ with antidiabetic actions. Darglitazone is effective in controlling blood glucose and lipid metabolism. | |||
T2824 | Pedunculoside | Others , Fatty Acid Synthase | |
Pedunculoside is extracted from Ilex rotunda Thunb. | |||
T3867 | Alpinetin | (-)-alpinetin | BCL , PPAR |
Alpinetin ((-)-alpinetin) has antibacterial activity.Alpinetin has anti-inflammatory activity.Alpinetin can enhance the sensitivity of HepG2 hepatoma cells to the chemotherapeutic agent CDDP. Alpinetin has strong anti-he... | |||
TQ0156 | GW1929 | PPAR | |
GW1929 is a potent PPAR-γ agonist (pKi: 8.84 for human PPAR-γ; pEC50s of 8.56 and 8.27 for human and murine PPAR-γ). | |||
T5532 | BMS-687453 | PPAR | |
BMS-687453 is a potent and selective PPAR alpha agonist, with an EC(50) of 10 nM for human PPARalpha and approximately 410-fold selectivity vs human PPARgamma in PPAR-GAL4 transactivation assays. | |||
T6689 | T0070907 | PPAR | |
T0070907(IC50=1 nM) , an effective and specific PPARγ inhibitor, with the >800-fold selectivity over PPARα and PPARδ. | |||
T15945 | MA-0204 | PPAR | |
MA-0204 is a highly selective and orally available peroxisome proliferator-activated receptor δ (PPARδ) modulator (EC50s: 0.4 nM, 7.9 nM and 10 nM for human, mouse and rat PPARδ, respectively). It is a potential treatmen... | |||
T8374 | LJ570 | PPAR | |
LJ570 is the first PPARα/γ dual agonist (PPARα,PPARγ with EC50s of 1.05 and 0.12 μM, respectively[) | |||
T1941 | GSK3787 | PPAR | |
GSK3787 is a specific and irreversible PPARδ inhibitor(pIC50= 6.6). | |||
T2674 | GSK0660 | PPAR | |
GSK0660 is an antagonist and inverse agonist of PPARβ/δ. | |||
T7159 | L-165041 | PPAR | |
L-165041 is a potent and selective agonist of the nuclear receptor PPARβ and PPARδ(Ki = 9 nM, EC50 = ~500 nM ,respectively) | |||
T4408 | Elafibranor | GFT505 | PPAR |
Elafibranor (GFT505) is an agonist of the peroxisome proliferator-activated receptor-α (PPAR-α) and peroxisome proliferator-activated receptor-δ (PPAR-δ) with EC50 values of 45 and 175 nM, respectively. | |||
T16350 | NSC-87877 | Apoptosis , Phosphatase | |
NSC-87877 is an effective inhibitor of Shp2 and Shp1 protein tyrosine phosphatases (IC50=0.318 μM, 0.355 μM of shp2 and shp1, respectively).It also inhibits dual-specificity phosphatase 26 (DUSP26). | |||
T7395 | Lanifibranor | IVA337 | PPAR |
Lanifibranor (IVA337) is an agonist of peroxisome proliferator-activated receptors (PPARs) with EC50 values of 1,537, 866, and 206 nM for human recombinant PPARα, PPARβ, and PPARγ, respectively, for transactivation activ... | |||
T24827 | SR 16832 | SR-16832,SR16832 | PPAR |
SR 16832 is a dual-site PPARγ inhibitor. It also inhibits the binding of endogenous ligands and transcriptional activity of PPARγ, more effectively than the orthosteric covalent antagonist GW 9662 and T 0070907. | |||
T8486 | GW6471 | GW 6471 | PPAR |
GW6471 is an antagonist of PPARα with IC50 of 0.24 μ M. GW6471 enhances the binding affinity of the PPAR α ligand-binding domain to the co-repressor proteins SMRT and NCoR. | |||
T9808 | Tetradecylthioacetic acid | PPAR | |
Tetradecylthioacetic acid is a synthetic fatty acid with a sulfur substitution in the β-position. This modification renders TTA unable to undergo complete β-oxidation and increases its biological activity, including acti... |