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WAY-620472

Name: WAY-620472
Brand: TargetMol
SKU: T77612
Price: 82 USD
Availability: InStock
Rating: 5 (10 reviews)

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Catalog No. T77612Cas No. 686769-90-4

WAY-620472 is a PPAR regulator that can be used to alter the lifespan of eukaryotes.

WAY-620472

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Purity: 98.99%

Catalog No. T77612Cas No. 686769-90-4

WAY-620472 is a PPAR regulator that can be used to alter the lifespan of eukaryotes.

Pack Size	Price	USA Warehouse	Global Warehouse
1 mg	$82	-	In Stock
5 mg	$181	-	In Stock
10 mg	$267	-	In Stock
25 mg	$413	-	In Stock
50 mg	$571	-	In Stock
100 mg	$763	-	In Stock
200 mg	$1,030	-	In Stock

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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]

All TargetMol products are for research purposes only and cannot be used for human consumption. We do not provide products or services to individuals. Please comply with the intended use and do not use TargetMol products for any other purpose.

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Batch Information

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Purity:98.99%

Appearance:Solid

Color:Orange

Resource Download

COA HNMR LCMS

Product Introduction

WAY-620472 AI Summary

WAY-620472 exhibits multiple bioactivities across various biological systems. It has been shown to inhibit mitochondrial division and modulate mitochondrial fusion, enhance SMN2 splice variant expression, and affect Firefly Luciferase activity. The compound inhibits Tau fibril formation, Thioflavin T binding, and the activity of Aldehyde Dehydrogenase 1 (ALDH1A1). It modulates lipid storage in Drosophila S3 cells and inhibits the function of the Influenza NS1 protein. Additionally, WAY-620472 inhibits the ERK signaling pathway, Anthrax Lethal Toxin Internalization, and HPGD (15-Hydroxyprostaglandin Dehydrogenase). It also disrupts the Ras-converting Enzyme/Cell Proliferation pathway and ELG1-dependent DNA repair mechanisms. This compound exhibits cytotoxicity in mammalian cells and shows properties as both an inhibitor and activator of firefly luciferase. Furthermore, it inhibits the Hepatitis C Virus (HCV) and acts as an agonist of the gsp mutation linked to Fibrous Dysplasia/McCune-Albright Syndrome. Lastly, it inhibits human tyrosyl-DNA phosphodiesterase 1 (TDP1) in both the presence and absence of CPT..

Note: Summary generated by AI. Data source: ChEMBL

Bioactivity

Description

WAY-620472 is a PPAR regulator that can be used to alter the lifespan of eukaryotes.

Chemical Properties

Molecular Weight	415.51
Formula	C₂₃H₂₁N₅OS
Cas No.	686769-90-4
Smiles	C(=O)(C=1C(=NN(C1)C2=CC=CC=C2)C3=CC=CS3)N4CCN(CC4)C5=CC=CC=N5

Storage & Solubility Information

Storage

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

Solubility Information

DMSO: 55 mg/mL (132.37 mM), Sonication is recommended.

Solution Preparation Table

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.4067 mL	12.0334 mL	24.0668 mL	120.3340 mL
5 mM	0.4813 mL	2.4067 mL	4.8134 mL	24.0668 mL
10 mM	0.2407 mL	1.2033 mL	2.4067 mL	12.0334 mL
20 mM	0.1203 mL	0.6017 mL	1.2033 mL	6.0167 mL
50 mM	0.0481 mL	0.2407 mL	0.4813 mL	2.4067 mL
100 mM	0.0241 mL	0.1203 mL	0.2407 mL	1.2033 mL

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In Vivo Formulation Calculator (Clear solution)

Please enter your animal experiment information in the following box and click Calculate to obtain the stock solution preparation method and in vivo formula preparation method:

For example, if the intended dosage is 10 mg/kg for animals weighing 20 g , with a dosing volume of 100 μL per animal, TargetMol | Animal experiments

and a total of 10 animals are to be administered, using a formulation of TargetMol | reagent

10% DMSO+ 40% PEG300+ 5% Tween 80+ 45% Saline/PBS/ddH₂O , the resulting working solution concentration would be 2 mg/mL.

Stock Solution Preparation:

Dissolve 2 mg of the compound in 100 μL DMSO TargetMol | reagent to obtain a stock solution at a concentration of 20 mg/mL . If the required concentration exceeds the compound's known solubility, please contact us for technical support before proceeding.

Preparation of the In Vivo Formulation:

1) Add 100 μL of the DMSO TargetMol | reagent stock solution to 400 μL PEG300 and mix thoroughly until the solution becomes clear.

2) Add 50 μL Tween 80 and mix well until fully clarified.

3) Add 450 μL Saline,PBS or ddH₂O TargetMol | reagent and mix thoroughly until a homogeneous solution is obtained.

This example is provided solely to demonstrate the use of the In Vivo Formulation Calculator and does not constitute a recommended formulation for any specific compound. Please select an appropriate dissolution and formulation strategy based on your experimental model and route of administration.

All co-solvents required for this protocol, includingDMSO, PEG300/PEG400, Tween 80, SBE-β-CD, and Corn oil, are available for purchase on the TargetMol website.

Dose Conversion

You can also refer to dose conversion for different animals. More Dose Conversion

Tech Support

Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc