Shopping Cart
  • Remove All
  • TargetMol
    Your shopping cart is currently empty
Filter
Applied FilterClear all
TargetMol | Tags By Target
  • DNA/RNA Synthesis
    (44)
  • HCV Protease
    (40)
  • HIV Protease
    (40)
  • SARS-CoV
    (34)
  • Influenza Virus
    (21)
  • Virus Protease
    (20)
  • Topoisomerase
    (19)
  • Antibacterial
    (17)
  • Antibiotic
    (16)
  • Others
    (350)
Filter
Search Result
Results for "

replication

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    633
    TargetMol | Inhibitors_Agonists
  • Compound Libraries
    2
    TargetMol | Compound_Libraries
  • Peptide Products
    22
    TargetMol | Peptide_Products
  • Inhibitory Antibodies
    2
    TargetMol | Inhibitory_Antibodies
  • Dye Reagents
    1
    TargetMol | Dye_Reagents
  • PROTAC Products
    5
    TargetMol | PROTAC
  • Natural Products
    60
    TargetMol | Natural_Products
  • Recombinant Protein
    133
    TargetMol | Recombinant_Protein
  • Isotope Products
    9
    TargetMol | Isotope_Products
  • Antibody Products
    3
    TargetMol | Antibody_Products
  • Disease Modeling
    3
    TargetMol | Disease_Modeling_Products
  • Cell Research
    4
    TargetMol | Inhibitors_Agonists
Prexasertib
LY2606368
T43101234015-52-1
Prexasertib (LY2606368) is an inhibitor of checkpoint kinase 1 (chk1) with potential antineoplastic activity.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Hot
Elimusertib
BAY-1895344
T73181876467-74-1
Elimusertib (BAY-1895344) is a potent, highly selective, and orally available ATR inhibitor with an IC50 of 7 nM, demonstrating significant anti-tumor efficacy as a monotherapy and strong combination potential with targeted alpha therapy Radium-223 dichloride.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Hot
Ganciclovir
RS-21592, BW 759, 2'-Nor-2'-deoxyguanosine
T068882410-32-0
Ganciclovir (2'-Nor-2'-deoxyguanosine) is an ACYCLOVIR analog that is a potent inhibitor of the Herpesvirus family including cytomegalovirus. Ganciclovir is used to treat complications from AIDS-associated cytomegalovirus infections.
  • Inquiry Price
Size
QTY
Lopinavir
ABT-378
T1623192725-17-0
Lopinavir (ABT-378) is a peptidomimetic HIV protease inhibitor effective against HIV protease with the Val 82 mutation. It is less affected by serum protein binding compared to the structurally related drug ritonavir.
  • Inquiry Price
Size
QTY
Thymidine
Thymidin, NSC 21548, DThyd, Deoxyribothymidine, 5-Methyldeoxyuridine
TWP291150-89-5
Thymidine (DThyd) is a cell synchronizing agent and a specific precursor of deoxyribonucleic acid. Thymidine inhibits DNA synthesis and can cause cell cycle arrest in the G1 S phase.
  • Inquiry Price
Size
QTY
IMB-301
T921264009-84-3
IMB-301 is a small molecular inhibitor via virtual screening according to the hA3G model.
  • Inquiry Price
Size
QTY
IMP-1088
T93502059148-82-0
IMP-1088 is a potent inhibitor of human N-myristoyltransferases NMT1 and NMT2 dual.
  • Inquiry Price
Size
QTY
hiv-1 inhibitor-6 
3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-
T98541821309-39-0
HIV-1 inhibitor-6 (3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo-) is a potent HIV-1 pre-mRNA selective splicing inhibitor that blocks HIV replication.
  • Inquiry Price
Size
QTY
IAV replication-IN-1
T2032732327297-30-1
IAV replication-IN-1 (compound 3h) can reduce the upregulation of inflammatory factors and apoptosis caused by IAV infection and alleviate lung damage resulting from IAV infection.
  • Inquiry Price
Size
QTY
Theaflavin 3,3′-digallate
Theaflavin 3,3′-di-O-gallate, Theaflavin 3, TFDG
T542930462-35-2
Theaflavin 3,3'-digallate, a major polyphenol found in black tea, is an inducer of oxidative stress which has anti-inflammatory and cancer chemopreventive actions, it reduces tumor angiogenesis by downregulating HIF-1αand VEGF.
  • Inquiry Price
Size
QTY
Oxaliplatin
L-OHP
T016461825-94-3
Oxaliplatin (L-OHP) is a DNA alkylating agent, an inhibitor of DNA synthesis. Oxaliplatin causes DNA cross-linking damage, preventing DNA replication and transcription and leading to cell death. Oxaliplatin induces autophagy.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Hot
Niclosamide
Niclocide, BAY2353
T071150-65-7
Niclosamide (Niclocide)(BAY2353) is used to treat most tapeworm infections by inhibiting DNA replication.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Hot
Temozolomide
TZM, TMZ, NSC 362856, CCRG 81045
T117885622-93-1
Temozolomide (TMZ) is a DNA alkylating agent with blood-brain barrier permeability and oral activity. Temozolomide has antitumor activity and antiangiogenic activity, and also induces apoptosis and autophagy. Temozolomide is stable under acidic conditions and hydrolyzes under neutral or slightly alkaline conditions.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Hot
Cosalane
NSC-658586, NSC 658586, NSC 640067
T23910154212-56-3In house
Cosalane (NSC 658586) is an HIV replication inhibitor, an inhibitor of chemokine receptor 7 (CCR7) signalling in humans and mice, with antiviral activity that blocks the binding of CCR7 to its natural ligands, CCL19 and CCL21.
  • Inquiry Price
6-8 weeks
Size
QTY
TargetMol | Inhibitor Hot
Astragaloside IV
AST-IV, AS-IV
T297384687-43-4
Astragaloside IV (AS-IV), an active component isolated from Astragalus membranaceus, suppresses the activation of ERK1 2 and JNK, and downregulates matrix metalloproteases (MMP)-2, (MMP)-9 in MDA-MB-231 breast cancer cells. Astragaloside IV is a bioactive saponin first isolated from the dried plant roots of the genus Astragalus, which is used in traditional Chinese medicine.1 It dose-dependently inhibits human adenovirus type 3 (HAdV-3) in A549 cells (IC50 = 23 μM; LC50 = 865 μM).It inhibits replication of HAdV-3 and decreases HAdV-3-induced apoptosis. It has diverse protective effects for the cardiovascular, immune, digestive, and nervous systems. In particular, it reduces myocardial infarct size in dogs when administered prior to coronary ligation and reduces reperfusion arrhythmias in isolated rat hearts.
  • Inquiry Price
Size
QTY
TargetMol | Inhibitor Hot
aoh1996
T775202089314-64-5In house
AOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen), targeting the transcription-replication conflict (TRC). It interferes with the interaction of PCNA with its binding proteins, leading to DNA replication stress and apoptosis. AOH1996 causes proteasome-dependent rpb1 degradation and lethal DNA damage by stabilizing the interaction between PCNA and RNA polymerase II, and acts synergistically with DNA damaging agents to inhibit tumor cell growth.
  • Inquiry Price
7-10 days
Size
QTY
TargetMol | Inhibitor Hot
AOH1160
N-(2-Oxo-2-(2-phenoxyphenylamino)ethyl)-1-naphthamide
T103432089314-57-6In house
AOH1160 is an inhibitor of proliferating cell nuclear antigen (PCNA). AOH1160 induces apoptosis and causes cell-cycle arrest by interfering with DNA replication.
  • Inquiry Price
6-8 weeks
Size
QTY
hDHODH-IN-3
DHODH-IN-2
T110251644156-80-8In house
hDHODH-IN-3 is an inhibitor of human dihydroorotate dehydrogenase with a pMIC50 value of 8.6. hDHODH-IN-3 can inhibit measles virus replication.
  • Inquiry Price
6-8 weeks
Size
QTY
hDHODH-IN-4
DHODH-IN-5
T110281644156-56-8In house
hDHODH-IN-4 (DHODH-IN-5) is a potent inhibitor of human dihydrogen dehydrogenase (DHODH). For human recombinant DHODH, its pIC50 is 7.8. hDHODH-IN-4 inhibits measles virus replication with a pMIC50 of 8.8.
  • Inquiry Price
6-8 weeks
Size
QTY
TTP-8307
TTP8307
T13221950225-08-8In house
TTP-8307 is an antiviral compound that inhibits the replication of rhinoviruses and enteroviruses, and inhibits coxsackievirus B3 and poliovirus by interfering with viral RNA synthesis.TTP-8307 can be used in the study of viral infections.
  • Inquiry Price
6-8 weeks
Size
QTY
Fiacitabine
FOAC, FIAC, NSC 382097
T1528069123-90-6In house
Fiacitabine (NSC-382097) is a selective inhibitor of DNA replication of the herpes simplex virus(HSV) (IC50: 2.5 nM and 12.6 nM for HSV1 and HSV2, respectively).
  • Inquiry Price
Size
QTY
Lagociclovir
MIV-210
T1570492562-88-4In house
Lagociclovir (MIV-210), a nucleoside analogue, is an antiviral compound available for the treatment of HBV82 that inhibits the replication of wild-type hepatitis B virus (HBV) in human hepatocellular carcinoma cell lines that permanently express HBV.
  • Inquiry Price
6-8weeks
Size
QTY
Azaribine
NSC 67239, 2',3',5'-Tri-O-acetyl-6-azauridine
T251302169-64-4In house
Azaribine (2;,3;,5;-Tri-O-acetyl-6-azauridine) is an orotate monophosphate decarboxylase (OMPD) inhibitor with broad-spectrum antiviral activity, inhibiting viral genome replication and gene transcription.Azaribine has been used in the study of Zika virus (ZIKV) infections, and in the study of psoriasis, arthritis and mycosis fungoides. Azaribine is used to study Zika virus (ZIKV) infections, psoriasis and mycosis fungoides.
  • Inquiry Price
7-10 days
Size
QTY
Ecomustine
T2536198383-18-7In house
Ecomustine is a water-soluble nitrosoureido sugar derived from acosamine, with alkylating activity. Ecomustine is a novel antitumor compound that alkylates and crosslinks DNA, thereby inhibiting replication and transcription and eventually resulting in a reduction of cellular proliferation.
  • Inquiry Price
3-6 months
Size
QTY