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Search Results for " mrna "

20

Compounds

Cat No. Product Name Synonyms Targets
T82494 EGFP mRNA-LNP
eGFP mRNA-LNP is a lipid nanoparticle encapsulating eGFP mRNA, designed for assessments of RNA delivery, translation efficiency, and cell viability. The eGFP mRNA, once internalized by cells, expresses Enhanced Green Flu...
T75103 CD19 CAR mRNA
CD19 CAR mRNA is designed to express the CD19 chimeric antigen receptor (CAR) protein, pivotal in chimeric antigen receptor T cell (CAR-CD19) immunotherapy. This receptor targets CD19, a membrane antigen crucial for B ce...
T75114 CD19 car mRNA-LNP
CD19 car mRNA-LNP, a lipid nanoparticle (LNP) encapsulating CD19 car mRNA, is instrumental in assessing RNA delivery, translation efficacy, and cell viability among other applications. This compound is pivotal for chimer...
T75116 COVID-19 Spike Protein mRNA-LNP
COVID-19 Spike Protein mRNA-LNP is a lipid nanoparticle (LNP) formulated with the novel coronavirus pneumonia spike protein, positioned on the membrane surface, designed for applications such as RNA delivery, translation...
T82495 EGFP mRNA(N1-Me-Pseudo UTP)
eGFP mRNA encodes the green fluorescent protein, originally derived from the jellyfish Aequorea victoria, and serves as a widely utilized direct detection reporter in mammalian cell culture. This protein produces a disti...
T82397 Firefly Luciferase mRNA(N1-Me-Pseudo UTP)
Firefly Luciferase mRNA, derived from Photinus pyralis (Firefly), codes for a bioluminescent enzyme widely utilized as a reporter in gene regulation and function analyses. This enzyme facilitates assays pertaining to gen...
T75102 COVID-19 Spike Protein mRNA(N1-Me-Pseudo UTP)
The COVID-19 Spike Protein mRNA, responsible for expressing the COVID-19 spike protein, is crucial for evaluating RNA delivery, translation efficiency, and cell viability. Positioned on the membrane surface, this spike p...
T1481 Fudosteine Others
Fudosteine is a novel mucoactive agent and a MUC5AC mucin hypersecretion inhibitor.
T9410 SM-102 Others
SM-102 is an ionizable amino lipid utilized in the synthesis of lipid nanoparticles (LNPs)[1]. It exhibits promise in the creation of LNPs dedicated to the transportation of mRNA-based vaccines[2].
T35648 4-Thiouridine Others
4-Thiouridine (4-SU) is a photoactivatable ribonucleoside analog that is widely used for RNA analysis, including short-range RNA-RNA crosslinking and nascent RNA labeling. The crosslinking thio moiety is attached directl...
T7138 FB23-2 Apoptosis , Others
FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor(IC50 : 2.6 μM).
T16674 Pseudouridine Endogenous Metabolite
Pseudouridine is the most abundant modified nucleoside in non-coding RNAs. It enhances the function of transfer RNA and ribosomal RNA by stabilizing RNA structure.
T22089 HPI 1 Hedgehog/Smoothened
HPI 1 is a hedgehog (Hh) signaling inhibitor. Inhibits Sonic hedgehog (Shh)-, SAG- and Gli-induced Hh pathway activation in Shh-LIGHT2 cells (IC50 values are 1.5, 1.5, 4, and 6 μM for Shh-, SAG-, Gli2- and Gli1-induced a...
T5S0246 Pseudoprotodioscin Others , Fatty Acid Synthase
1. Pseudoprotodioscin has moderate cytotoxicity.
TQ0218 Deoxyandrographolide 14-deoxyandrographolide IL Receptor , TNF
Deoxyandrographolide (14-deoxyandrographolide) potentiates NGF-induced neurite outgrowth. Deoxyandrographolide suppresses the production of proinflammatory mediators TNF-α and IL-6.
T0094 Budesonide Entocort,Pulmicort,Rhinocort Glucocorticoid Receptor
Budesonide (Pulmicort), an anti-inflammatory corticosteroid, has shown the effective glucocorticoid activitie and few mineralocorticoid activities. According to reports, Budesonide has extensively inhibitory effects agai...
T16698 Pyronin Y C.I. 45005,Pyronine G Others
Pyronin Y (Pyronine G) is an intercalating cationic dye that shows specificity towards RNA.
T10760 Ceramides Mixture Telomerase
Ceramides Mixture, an endogenous ceramide, consists of hydroxy and non-hydroxy fatty acid-containing ceramides. It is involved in the regulation of cell cycle arrest, growth inhibition, and modulation of telomerase activ...
TN1465 Cannabigerol NOS , 5-HT Receptor , ROS
Cannabigerol is a high affinity α±2-adrenergic receptor agonist, moderate affinity 5-HT1A receptor antagonist, and low affinity CB1 receptor antagonist ; also binds to the CB2 receptor; it can relieve interocular pressur...
T8972 FIT-039 Others , DNA/RNA Synthesis , CDK , HSV
FIT-039 is a selective and ATP-competitive, orally active inhibitor of CDK9( IC50 : 5.8 μM;CDK9/cyclin T1). FIT-039 inhibits replication of HSV-1 (IC50 of 0.69 μM), HSV-2, human adenovirus, and human CMV. FIT-039 is a pr...
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