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Search Results for " renal "

Targets

225

Compounds

54

Natural Products

185

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T13865 Resorcinolnaphthalein RAAS
Resorcinolnaphthalein is a specific enhancer of angiotensin-converting enzyme 2 (ACE2) (EC50 value of 19.5 μM).
T26046 Razoxane Topoisomerase
Razoxane is used as an antimitotic agent with immunosuppressive properties.
T10696 CB2 modulator 1 Cannabinoid Receptor
CB2 modulator 1 is a potent CB2 modulator. It can be used for the research for immune disorders, osteoporosis, inflammation, renal ischemia.
T6683 STF-62247 STF 62247 Estrogen/progestogen Receptor , Autophagy
STF-62247 is TGN inhibitor with IC50 of 0.625 μM and 16 μM in RCC4 and RCC4/VHL cells, respectively.
T2058 Palosuran ACT-058362 GPR
Palosuran (ACT-058362) (ACT-058362) is a new potent and specific antagonist of the human UT receptor.
T0114 Trichlormethiazide Naqua,Metahydrin,Trichlormetazid ATPase , Carbonic Anhydrase
Trichlormethiazide (Naqua) is a short-acting, 3-dichloromethyl derivative of hydrochlorothiazide, belonging to the class of thiazide diuretics. Trichlormethiazide appears to block the active reabsorption of chloride and ...
T2583 Cilastatin MK0791 Proteasome , Antibacterial , Antibiotic
Cilastatin (MK0791) is a renal dehydropeptidase-I and leukotriene D4 dipeptidase inhibitor. Since the antibiotic, IMIPENEM, is hydrolyzed by dehydropeptidase-I, which resides in the brush border of the renal tubule, cila...
T4989 Fosfomycin Tromethamine Antibacterial , Antibiotic
An antibiotic produced by Streptomyces fradiae.
T8494 NS-3-008 hydrochloride NS-3-008 HCl Others
NS-3-008 hydrochloride (NS-3-008 HCl) is a transcriptional G0/G1 switch 2 (G0s2) inhibitor( IC50 of 2.25 μM).
T7714 Temocapil Tyrosinase
Temocapril is an inhibitor of tyrosine kinase.
T12883 Fezagepras PBI-4050,Setogepram GPR
Fezagepras (Setogepram) is an orally active GPR40 agonist and is an antagonist or inverse agonist of GPR84 with anti-inflammatory, anti-fibrotic, and anti-proliferative actions.
T1410 Torsemide AC-4464,JDL-464,Torasemide Na-K-Cl cotransporter
Torsemide (AC-4464) is an anilinopyridine sulfonylurea belonging to the class of loop diuretics. Torsemide has a prolonged duration of action compared to other loop diuretics, is extensively protein bound in plasma and h...
T9831 MKC-1 Ro-31-7453 Apoptosis , Akt , Microtubule Associated , mTOR
MKC-1 (Ro-31-7453) is an orally bioavailable, small-molecule, bisindolylmaleimide cell cycle inhibitor with potential antineoplastic activity. MKC-1 and its metabolites inhibit tubulin polymerization, blocking the format...
T3131 Fosfomycin calcium Phosphomycin calcium salt,Fosmicin Antibacterial , Antibiotic
Fosfomycin calcium (Phosphomycin calcium salt) is a blood-brain barrier penetrating, broad-spectrum antibiotic by irreversibly inhibiting an early stage in cell wall synthesis.
T2456 Tivozanib AV-951,KRN951 VEGFR , PDGFR , Ephrin Receptor
Tivozanib (KRN951) is an orally bioavailable inhibitor of vascular endothelial growth factor receptors (VEGFRs) 1, 2 and 3 with potential antiangiogenic and antineoplastic activities.
T4583 PFI-2 hydrochloride (R)-PFI-2 hydrochloride,PFI-2 HCl Histone Methyltransferase
PFI-2 hydrochloride ((R)-PFI-2 hydrochloride) is a potent, highly selective, and cell-active inhibitor of the methyltransferase activity of SETD7 (IC50: 2 nM), 500 fold active than (S)-PFI-2.
T13748 L-2-Hydroxyglutaric acid disodium (S)-2-Hydroxyglutaric acid disodium Histone Demethylase , Mitochondrial Metabolism
L-2-Hydroxyglutaric acid disodium ((S)-2-Hydroxyglutaric acid disodium) is an epigenetic modifier and putative oncometabolite in renal cancer. L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activ...
T16708 R-268712 ALK , TGF-beta/Smad
R-268712 is a specific activin receptor-like kinase 5 (ALK5) inhibitor(IC50 of 2.5 nM). It is also an orally active transforming growth factor-β type I receptor inhibitor.
T1615 Irbesartan SR-47436,BMS-186295 Apoptosis , RAAS
Irbesartan (SR-47436) is an Angiotensin 2 Receptor Blocker. The mechanism of action of irbesartan is as an Angiotensin 2 Receptor Antagonist.
TQ0157 EIPA L593754,MH 12-43 Sodium Channel , TRP/TRPV Channel
EIPA (L593754) (L593754, MH 12-43) is a TRPP3 channel inhibitor (IC50: 10.5 μM). It also inhibits Na+/H+-exchanger (NHE) and macropinocytosis.
T6698 Temocapril hydrochloride CS-622 HCl,Acecol,Temocapril HCl,CS-622 RAAS
Temocapril hydrochloride (CS-622 HCl), the hydrochloride of Temocapril, is a long-acting ACE inhibitor used for the therapy of hypertension.
T1987 PFI-2 PFI2,PFI 2,(R)-PFI-2 Histone Methyltransferase
PFI-2 is an effective, specific and cell-active lysine methyltransferase SETD7 inhibitor (Ki/IC50: 0.33/2 nM), 1000-fold selectivity over other methyltransferases and other non-epigenetic targets.
T0248 Clorprenaline hydrochloride Clorprenaline HCl,NSC 334693 Adrenergic Receptor
Clorprenaline hydrochloride (Clorprenaline HCl) is a beta-2 adrenergic agonist with bronchodilator activity.
T13142L Theodrenaline hydrochloride Theodrenaline hydrochloride(13460-98-5 Free base) SARS-CoV
Theodrenaline hydrochloride is an inhibitor targeting SARS-CoV-2 for the study of hypotension induced by spinal anesthesia.
T0871 Noradrenaline bitartrate Adrenergic Receptor
Norepinephrine bitartrate acts directly on the α- and β-adrenergic receptors. Norepinephrine Bitartrate is a bitartrate salt of norepinephrine, a synthetic phenylethylamine that mimics the sympathomimetic actions of the ...
T1056 Isoprenaline hydrochloride NCI-c55630,Isoproterenol hydrochloride,Isoprenaline HCl PI3K , Endogenous Metabolite , Adrenergic Receptor , PDE
Isoprenaline hydrochloride (NCI-c55630) is a potent beta-adrenergic agonist with the peripheral vasodilator, bronchodilator, and cardiac stimulating properties.
T0948 Adrenalone hydrochloride Adrenalone HCl Adrenergic Receptor
Adrenalone hydrochloride (Adrenalone HCl) is a dopamine β-oxidase inhibitor with a similar structure to the norepinephrine transporter (NET) ligand, with an IC50 of 36.9 μM. It is an adrenergic agonist that acts as a loc...
T32536 L-Adrenalin ascorbinate Tonhormon
l-Adrenalin ascorbinate is a bioactive chemical.
T32697 Levisoprenaline (R)-Isoprenaline,Levisoprenalina,BRN-3203136,BRN 3203136,Proternol L
Levisoprenaline is a bioactive chemical.
T27540 Hexoprenaline Sulfate ST-1512,Argocian,Gynipral
Hexoprenaline Sulfate is a selective beta2-adrenoreceptor agonist. Hexoprenaline Sulfate is active in man as a bronchodilator by the oral or intravenous routes and by inhalation. Hexoprenaline Sulfate is indicated for us...
T33361 Metiprenaline Egyt 402,Egyt-402,Egyt402
Metiprenaline is a biochemical.
T25984 Prenalterol H80/62,H-80/62,H 80/62
Prenalterol is a selective β1-adrenergic receptor agonist. Prenalterol has no effect on gut smooth muscle contractile activity. Prenalterol has potential to be used for researching cardiovascular disease [1].
T69000 Prenalterol hydrochloride
Prenalterol hydrochloride is a partial adrenergic agonist with functional beta 1-receptor specificity and inotropic effect. It is effective in the treatment of acute cardiac failure, postmyocardial infarction low-output ...
T13142 Theodrenaline (±)​-​Theodrenaline Others
Theodrenaline is a cardiac stimulant, also acts as an agent of anti-hypotensive together with cafedrine.
T68979 Prenalterol (free base)
Prenalterol (free base) is a selective inotropic beta-adrenoceptor agonist. It is used as a cardiac stimulant.
T25499 Hexoprenaline
Hexoprenaline is a stimulant of adrenergic beta 2 receptors used as a bronchodilator, antiasthmatic agent, and tocolytic agent.
T60261 Clorprenaline
Clorprenaline is a potent agonist of β2-adrenergic. Clorprenaline promotes animal muscular mass growth and decreases fat accumulation that is a potential new lean meat-boosting feed additive [1].
T69151 Adrenaline sulfate
Adrenaline sulfate is a orally active hormone secreted by the medulla of the adrenal glands. Adrenaline sulfate is an α-adrenergic and β-adrenergic receptor agonist. Adrenaline sulfate can be used in the treatment of ana...
T1400L Demeclocycline Ledermycin,Bioterciclin,Deteclo,Declostatin,Deganol Antibacterial
Demeclocycline (Declostatin) is a tetracycline antibiotic produced by a strain of Streptomyces aureofaciens.Demeclocycline has antimicrobial activity and inhibits the action of vasopressin on the renal tubules, leading t...
T24270 KS370G KS-370-G,KS 370 G,Caffeic Acid Phenethyl Amide
KS370G (Caffeic Acid Phenethyl Amide) inhibits UUO-induced renal fibrosis marker expression. KS370G is an orally active hypoglycemic and cardioprotective agent that reduces collagen deposition in obstructed kidneys and s...
T3064 VTP-27999 VTP27999 RAAS
VTP-27999 is an alkyl amine Renin inhibitor. VTP-27999 has been used in trials studying the basic science of Renal Function.
T27323 FK-453 FK453,FK 453 Adenosine Receptor
FK-453 is a potent antagonist of non-xanthine adenosine A1 receptor with diuretic and renal vasodilatory activity.
TP1049L Ornipressin Acetate(3397-23-7,free) Orpressin,POR-8 Others
Ornipressin Acetate (POR-8) is a potent vasoconstrictor, hemostatic and renal agent.
T22882 JP1302 Adrenergic Receptor
JP1302 is a selective α2C adrenoceptor antagonist with a Kb value of 16 nM and a Ki of 28 nM for human α2C receptors.JP1302 has antidepressant activity, disrupts the FACT complex and degrades histone H1.JP1302 has been u...
T50000 2-Iodohippuric Acid Others
2-Iodohippuric Acid is an organic compound that can be used to measure renal clearance for renal function studies, and for the diagnosis of certain diseases, such as liver and kidney disease. In addition, it is used in t...
T16777 ROC-325 Apoptosis , Autophagy
ROC-325 is an effective and orally active inhibitor of autophagy with anticancer activity. ROC-325 induces renal cell carcinoma apoptosis and exhibits favorable selectivity.
T13881 Dicirenone SC26304 ATPase , Glucocorticoid Receptor
Dicirenone (SC26304) inhibits the Mineralocorticoid receptor (MR), aldosterone regulation of the urinary K+:Na+ ratio, and aldosterone binding to renal cytoplasmic and nuclear receptors.
T2316 Omarigliptin MK-3102 Proteasome , DPP-4
Omarigliptin (MK-3102) has been used in trials studying the treatment of Type 2 Diabetes Mellitus and Chronic Renal Insufficiency.
T14076 A 839977 A839977,A-839977 P2X Receptor , Calcium Channel
A 839977 is a selective P2X7 receptor antagonist with anti-inflammatory and analgesic activity that inhibits BzATP-induced calcium efflux from the P2X7 receptor for the study of renal fibrosis.
T1430 Betamipron CS-443,N-Benzoyl-β-alanine Antibacterial , Antibiotic
Betamipron (CS-443) is used combination with panipenem to prevent nephrotoxicity and inhibit panipenem uptake into the renal tubule.

Compounds

Resorcinolnaphthalein
T13865
Synonym:
Target: RAAS
Razoxane
T26046
Synonym:
Target: Topoisomerase
CB2 modulator 1
T10696
Synonym:
Target: Cannabinoid Receptor
STF-62247
T6683
Synonym: STF 62247
Target: Estrogen/progestogen Receptor, Autophagy
Palosuran
T2058
Synonym: ACT-058362
Target: GPR
Trichlormethiazide
T0114
Synonym: Naqua,Metahydrin,Trichlormetazid
Target: ATPase, Carbonic Anhydrase
Cilastatin
T2583
Synonym: MK0791
Target: Proteasome, Antibacterial, Antibiotic
Fosfomycin Tromethamine
T4989
Synonym:
Target: Antibacterial, Antibiotic
NS-3-008 hydrochloride
T8494
Synonym: NS-3-008 HCl
Target: Others
Temocapil
T7714
Synonym:
Target: Tyrosinase
Fezagepras
T12883
Synonym: PBI-4050,Setogepram
Target: GPR
Torsemide
T1410
Synonym: AC-4464,JDL-464,Torasemide
Target: Na-K-Cl cotransporter
MKC-1
T9831
Synonym: Ro-31-7453
Target: Apoptosis, Akt, Microtubule Associated, mTOR
Fosfomycin calcium
T3131
Synonym: Phosphomycin calcium salt,Fosmicin
Target: Antibacterial, Antibiotic
Tivozanib
T2456
Synonym: AV-951,KRN951
Target: VEGFR, PDGFR, Ephrin Receptor
PFI-2 hydrochloride
T4583
Synonym: (R)-PFI-2 hydrochloride,PFI-2 HCl
Target: Histone Methyltransferase
L-2-Hydroxyglutaric acid disodium
T13748
Synonym: (S)-2-Hydroxyglutaric acid disodium
Target: Histone Demethylase, Mitochondrial Metabolism
R-268712
T16708
Synonym:
Target: ALK, TGF-beta/Smad
Irbesartan
T1615
Synonym: SR-47436,BMS-186295
Target: Apoptosis, RAAS
EIPA
TQ0157
Synonym: L593754,MH 12-43
Target: Sodium Channel, TRP/TRPV Channel
Temocapril hydrochloride
T6698
Synonym: CS-622 HCl,Acecol,Temocapril HCl,CS-622
Target: RAAS
PFI-2
T1987
Synonym: PFI2,PFI 2,(R)-PFI-2
Target: Histone Methyltransferase
Clorprenaline hydrochloride
T0248
Synonym: Clorprenaline HCl,NSC 334693
Target: Adrenergic Receptor
Theodrenaline hydrochloride
T13142L
Synonym: Theodrenaline hydrochloride(13460-98-5 Free base)
Target: SARS-CoV
Noradrenaline bitartrate
T0871
Synonym:
Target: Adrenergic Receptor
Isoprenaline hydrochloride
T1056
Synonym: NCI-c55630,Isoproterenol hydrochloride,Isoprenaline HCl
Target: PI3K, Endogenous Metabolite, Adrenergic Receptor, PDE
Adrenalone hydrochloride
T0948
Synonym: Adrenalone HCl
Target: Adrenergic Receptor
l-Adrenalin ascorbinate
T32536
Synonym: Tonhormon
Target:
Levisoprenaline
T32697
Synonym: (R)-Isoprenaline,Levisoprenalina,BRN-3203136,BRN 3203136,Proternol L
Target:
Hexoprenaline Sulfate
T27540
Synonym: ST-1512,Argocian,Gynipral
Target:
Metiprenaline
T33361
Synonym: Egyt 402,Egyt-402,Egyt402
Target:
Prenalterol
T25984
Synonym: H80/62,H-80/62,H 80/62
Target:
Prenalterol hydrochloride
T69000
Synonym:
Target:
Theodrenaline
T13142
Synonym: (±)​-​Theodrenaline
Target: Others
Prenalterol (free base)
T68979
Synonym:
Target:
Hexoprenaline
T25499
Synonym:
Target:
Clorprenaline
T60261
Synonym:
Target:
Adrenaline sulfate
T69151
Synonym:
Target:
Demeclocycline
T1400L
Synonym: Ledermycin,Bioterciclin,Deteclo,Declostatin,Deganol
Target: Antibacterial
KS370G
T24270
Synonym: KS-370-G,KS 370 G,Caffeic Acid Phenethyl Amide
Target:
VTP-27999
T3064
Synonym: VTP27999
Target: RAAS
FK-453
T27323
Synonym: FK453,FK 453
Target: Adenosine Receptor
Ornipressin Acetate(3397-23-7,free)
TP1049L
Synonym: Orpressin,POR-8
Target: Others
JP1302
T22882
Synonym:
Target: Adrenergic Receptor
2-Iodohippuric Acid
T50000
Synonym:
Target: Others
ROC-325
T16777
Synonym:
Target: Apoptosis, Autophagy
Dicirenone
T13881
Synonym: SC26304
Target: ATPase, Glucocorticoid Receptor
Omarigliptin
T2316
Synonym: MK-3102
Target: Proteasome, DPP-4
A 839977
T14076
Synonym: A839977,A-839977
Target: P2X Receptor, Calcium Channel
Betamipron
T1430
Synonym: CS-443,N-Benzoyl-β-alanine
Target: Antibacterial, Antibiotic
1 2 3 4 5
Cat No. Product Name Synonyms Targets
T5669 Citric acid monohydrate Others
Citric Acid Monohydrate is a tricarboxylic acid found in citrus fruits. Citric acid is used as an excipient in pharmaceutical preparations due to its antioxidant properties. It maintains stability of active ingredients a...
T5S0636 Citric acid Citro,Citretten Apoptosis , Others , Endogenous Metabolite , Antibacterial , Antibiotic
1. Citric acid (Citro) (1-2 g/kg) can decrease brain lipid peroxidation and inflammation, liver damage, and DNA fragmentation. 2. Citric acid denture cleansers can reduce C. albicans biofilm accumulation and cell viabili...
T22311 Djenkolic Acid jengkolic acid,Djenkolate,S,S'-Methylenebiscysteine Others
Djenkolic Acid (S,S'-Methylenebiscysteine) is a naturally occurring sulfur-containing amino acid extracted from djenkol beans(Archidendron pauciflorum), which is native to Southeast Asia. It is an uncommon but important ...
T8262 Fosfomycin sodium Fosfomycin Disodium Antibacterial , Antibiotic
Fosfomycin sodium is a bactericidal, low-molecular weight, broad-spectrum antibiotic, with putative activity against several bacteria, including multidrug-resistant Gram-negative bacteria, by irreversibly inhibiting an e...
T3999 D(+)-Galactosamine hydrochloride D-Galactosamine HCl Others
D(+)-Galactosamine hydrochloride (D-Galactosamine HCl) hepatotoxicity is associated with endotoxin sensitivity and mediated by lymphoreticular cells in mice.
T3033 Deoxycorticosterone acetate DOC acetate,Cortexone acetate,11-Deoxycorticosterone acetate Glucocorticoid Receptor , Endogenous Metabolite , Adrenergic Receptor
Deoxycorticosterone acetate (Cortexone acetate) is the 21-acetate derivative of desoxycorticosterone, used for intramuscular injection for replacement therapy of the adrenocortical steroid.
T8150 Nudifloramide 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide PARP , Endogenous Metabolite
Nudifloramide (1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide) is one of the end degradation products of nicotinamide-adenine dinucleotide (NAD).
T1071L DL-Adrenaline Hydrochloride Adrenergic Receptor
DL-Adrenaline Hydrochloride is the hydrochloride salt of the naturally occurring sympathomimetic amine with vasoconstricting, intraocular pressure-reducing activities.
TN4258 Isocuparenal Others
Isocuparenal is a natural product for research related to life sciences. The catalog number is TN4258 and the CAS number is 16982-01-7.
TN6974 (-)-Isobicyclogermacrenal
(-)-Isobicyclogermacrenal is a natural product.
T3P2855 Chamigrenal EGFR , NOS , PAFR , COX , Prostaglandin Receptor
β-Chamigrenal has anti-inflammatory activity, it has inhibitory effects on lipopolysaccharide-induced nitric oxide and prostaglandin E2 production in RAW 264.7 macrophages. Chamigrenal shows platelet-activating factor an...
T20173 Noradrenaline tartrate NSC 169106,NSC-169106,l-Noradrenaline d-bitartrate,NSC169106,Norepinephrine bitartrate
Norepinephrine bitartrate is a precursor of epinephrine. Norepinephrine is the principal transmitter of most postganglionic sympathetic fibers and of the diffuse projection system in the brain arising from the locus ceru...
T4238 Glycocyamine 2-Guanidinoacetic acid,Guanidoacetic acid Others , Endogenous Metabolite
Glycocyamine (2-Guanidinoacetic acid), a precursor of creatine, is a replacement of dietary arginine and could support overall energy homeostasis of the bird. Glycocyamine is an important marker for renal failure, kidney...
TQ0119 Cirsimaritin GABA Receptor
Cirsimaritin exhibits antibacterial, anti-inflammation, anti-tumor, antioxidant properties and renal protection. Cirsimaritin binds weakly to the benzodiazepine site on GABAA receptors.
T4959 DL-Mannitol Mannitol Others
DL-Mannitol is a osmotic diuretic, it may play a role in reducing off-target 68Ga-PSMA renal uptake
TN2430 Glucodigifucoside
Glucodigifucoside, a cardiac glycoside that can be isolated from digitalis seeds, is specifically cytotoxic to human renal adenocarcinoma cells.
T7344 SDMA NG,NG'-Dimethyl-L-arginine,Symmetric dimethylarginine Endogenous Metabolite
SDMA (Symmetric dimethylarginine) is the most potent endogenous inhibitor of nitric oxide synthase (NOS), with higher levels in patients with end-stage renal disease (ESRD).
T0414 D-Mannitol Mannite,Mannitol,Osmitrol Apoptosis , Dehydrogenase , Endogenous Metabolite
D-Mannitol (Mannitol) is a diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to t...
T5289 N-Acetyl-L-arginine dihydrate N-Ac-L-arg-OH Others , Endogenous Metabolite
N-Acetyl-L-arginine dihydrate (N-Ac-L-arg-OH) is one of the guanidino compounds found elevated in the serum of a hemodialyzed renal insufficient (uremic) pediatric population.
T1436 4-Aminohippuric Acid p-Aminohippuric acid Amino Acids and Derivatives , Endogenous Metabolite
4-Aminohippuric Acid is the glycine amide of 4-aminobenzoic acid. Its sodium salt is used as a diagnostic aid to measure effective renal plasma flow (ERPF) and excretory capacity.
T5040 Medroxyprogesterone Estrogen/progestogen Receptor , Progesterone Receptor
Medroxyprogesterone is used in the treatment of renal carcinoma. It is a synthetic progestational hormone used in veterinary practice as an estrus regulator.
T3869 Skimmin Skimmine Others
Skimmin (Skimmine) has anti-inflammatory activity, can significantly improve renal function and suppress the IgG deposition as well as the development of glomerular lesions in a rat model of membranous glomerulonephritis...
T2S0850 Malic acid E 296,2-Hydroxysuccinic acid,Hydroxybutanedioic acid,FDA 2018,Deoxytetraric acid,Pomalus acid Others , Endogenous Metabolite
1. Malic acid (Pomalus acid) did reduce populations of L. monocytogenes on poultry. 2. Malic acid supplementation may be useful for conservative treatment of calcium renal stone disease by virtue of its capacity to induc...
T3857 Magnolin (+)-Magnolin ERK
Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro. Magnolin has anti-inflammatory and antioxidative effects.
T7040 Angiotensin II human DRVYIHPF,Angiotensin II,Hypertensin II,Ang II Apoptosis , RAAS
Angiotensin II human (Ang II) is a biologically active peptide, a vasoconstrictor. Angiotensin II interacts with AT1R and AT2R to regulate blood pressure, stimulate sympathetic nerves, and increase aldosterone biosynthes...
T3005 4-Hydroxychalcone P-Cinnamoylphenol Others , NF-κB
4-Hydroxychalcone (P-Cinnamoylphenol) attenuates hyperaldosteronism, inflammation, and renal injury in cryptochrome-null mice.
T1614 Hydrocortisone Cortisol Glucocorticoid Receptor , Endogenous Metabolite
Hydrocortisone (Cortisol) is a glucocorticoid hormone secreted by the adrenocortex. Hydrocortisone agonizes the glucocorticoid receptor, which promotes proteolytic metabolism, gluconeogenesis, capillary wall stabilizatio...
T20793 Magnesium Lithospermate B Monomethyl lithospermate B,Lithospermate B Others
Magnesium Lithospermate B is a natural product activates eNOS and ameliorates endothelial dysfunction in diabetes by enhancing vasodilation in addition to reducing oxidative stress, it can protecte cardiomyocytes from is...
T4904 1-Methylguanidine hydrochloride Others , Endogenous Metabolite
Methylguanidine (MG) is a guanidine compound deriving from protein catabolism. It is also a product of putrefaction. Methylguanidine is a suspected uraemic toxin that accumulates in renal failure, however it also exhibit...
T3S1227 Aristolactam I Aristolactam,Aristololactam I,Aristololactum Apoptosis , Caspase
1.Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I may be mediated by different mechanisms except TGF...
PDK0014 3-Methylxanthine Endogenous Metabolite
3-Methylxanthine, a xanthine derivative, is a cyclic guanosine monophosphate (GMP) inhibitor, with an IC50 of 920 μM on guinea-pig isolated trachealis muscle.3-Methylxanthine inhibited xanthine crystallization, it could ...
T5S0761 Nitidine chloride Apoptosis , ERK , FAK , p38 MAPK , NF-κB , Topoisomerase , STAT , Parasite
1. Nitidine chloride has inhibitory effects on various tumors, such as renal cancer , breast cancer. 2. Nitidine chloride inhibits the proliferation of SMMC-7721 cells in vitro in a time- and dose-dependent manner and id...
T3414 Morroniside Apoptosis , MMP , Pyroptosis
Morroniside would act as a regulator of hepatic inflammatory reactions and lipid metabolism in db/db mice. It exhibits protective effects against diabetic renal damage and human umbilical vein endothelial cells, by inhib...
T2S2043 Dracorhodin perchlorate Dracorhodin perochlorate,Dracohodin perochlorate Apoptosis , Others
Dracorhodin perchlorate inhibits cell growth, and induces apoptosis in fibroblasts in a dose-and time-dependent manner, arresting cell cycle at G1 phase, may as a candidate for anti-breast cancer. Dracorhodin perchlorate...
T5248 (R)-3-Hydroxybutanoic acid Others , Endogenous Metabolite
3-hydroxybutyric acid is involved in the synthesis and degradation of ketone bodies. Like the other ketone bodies (acetoacetate and acetone), levels of beta-hydroxybutyrate are raised in the blood and urine in ketosis. B...
T3877 Esculentoside A NF-κB , COX
Esculentoside A can suppress inflammatory responses in LPS-induced ALI through inhibition of the NF-κB and mitogen-activated protein kinase signaling pathways. Esculentoside A may be useful for the treatment of autoimmun...
T6S1917 Schisandrol B Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B P450 , Reactive Oxygen Species , Autophagy
1. Schisandrol B (Besigomsin) may exert neuroprotective effects by attenuating the microglia-mediated neuroinflammatory response via inhibiting the TLR4-mediated NF-κB and MAPKs signaling pathways. 2. Schisandrol B has a...
T8053 N-Acetyl-L-arginine Ac-Arg-OH Endogenous Metabolite
N-Acetyl-L-arginine (Ac-Arg-OH) belongs to the class of organic compounds known as n-acyl-l-alpha-amino acids. These are n-acylated alpha amino acids which have the L-configuration of the alpha-carbon atom. N-a-Acetyl-L-...
T4938 Potassium 1H-indol-3-yl sulfate Indoxyl sulfate potassium salt,Potassium 3-indoxyl sulfate AhR , Endogenous Metabolite
Potassium 1H-indol-3-yl sulfate (Potassium 3-indoxyl sulfate) is an agonist for the human Aryl Hydrocarbon Receptor (AhR). The Aryl Hydrocarbon Receptor (AhR) has recently emerged as a pathophysiological regulator of imm...
T13670 (E)-Ligustilide Others
(E)-Ligustilide has renal protection and was isolated from Angelica sinensis.
TN1912 Marinobufogenin Marinobufagenin ATPase , EGFR
Marinobufagenin, a cardiotonic steroid, its increased concentrations are important in the cardiac disease and oxidant stress state seen with renal failure.
T72798 Ganodermaones B
Ganodermaones B is a renal fibrosis inhibitor. Ganodermaones B inhibits TGF-β1-induced collagen I and fibronectin expression .
T83110 Angulatin K
Angulatin K, a sesquiterpene polyol ester naturally occurring in the root bark of Celastrus angulatus [1], exhibits anti-cancer properties effective against a variety of solid tumors, including renal, breast, and lung.
TN4381 Karounidiol Others
Karounidiol exhibits cytotoxicity especially against a human renal cancer, it markedly suppresses the promoting effect of TPA (1 microgram/mouse) on skin tumor formation in mice following initiation with 7,12-dimethylben...
T11513 Gum arabic Arabic gum Others
Gum Arabic is an anti-oxidant and can protect against experimental hepatic-, renal- and cardiac toxicities. Gum Arabic also can be used in immunohistochemistry. Gum Arabic is a branched-chain, complex polysaccharide deri...
T13749 L-2-Hydroxyglutaric acid (S)-2-Hydroxyglutaric acid Others
L-2-Hydroxyglutaric acid inhibits mitochondrial creatine kinase (Mi-CK) activity with Km and Ki of 2.52 mM and 11.13 mM, respectively. L-2-Hydroxyglutaric acid is an epigenetic modifier and putative oncometabolite in ren...
TN3380 Alloisoimperatorin AChR
Alloisoimperatorin is a candidate of AChE inhibitors, it displays potent antioxidant effects against the DPPH radical and against renal epithelial cell injury by using AAPH to generate peroxyl radicals in vitro. Alloisoi...
TMA1743 Ergosterol peroxide ERK , VEGFR , p38 MAPK , Wnt/beta-catenin , Akt , JAK , CDK , JNK , STAT , Antifection
Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Foxo3a activity by inhibiting pAKT and c-Myc and activating pr...
T38484 Englerin A (-)-Englerin A TRP/TRPV Channel
Englerin A, a TRPC4 and TRPC5 channel agonist, is a compound from the East African plant Phyllanthus engleri with analgesic, anti-inflammatory, and anticancer activities that induces necrosis in human renal cancer cells.
TN3753 Dalbergioidin Tyrosinase , ROS , Akt , PI3K , TGF-beta/Smad
Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces bikiniensis that has commonly been used as an indicator or...
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Natural Products

Citric acid monohydrate
T5669
Synonym:
Target: Others
Citric acid
T5S0636
Synonym: Citro,Citretten
Target: Apoptosis, Others, Endogenous Metabolite, Antibacterial, Antibiotic
Djenkolic Acid
T22311
Synonym: jengkolic acid,Djenkolate,S,S'-Methylenebiscysteine
Target: Others
Fosfomycin sodium
T8262
Synonym: Fosfomycin Disodium
Target: Antibacterial, Antibiotic
D(+)-Galactosamine hydrochloride
T3999
Synonym: D-Galactosamine HCl
Target: Others
Deoxycorticosterone acetate
T3033
Synonym: DOC acetate,Cortexone acetate,11-Deoxycorticosterone acetate
Target: Glucocorticoid Receptor, Endogenous Metabolite, Adrenergic Receptor
Nudifloramide
T8150
Synonym: 1-Methyl-6-oxo-1,6-dihydropyridine-3-carboxamide
Target: PARP, Endogenous Metabolite
DL-Adrenaline Hydrochloride
T1071L
Synonym:
Target: Adrenergic Receptor
Isocuparenal
TN4258
Synonym:
Target: Others
(-)-Isobicyclogermacrenal
TN6974
Synonym:
Target:
Chamigrenal
T3P2855
Synonym:
Target: EGFR, NOS, PAFR, COX, Prostaglandin Receptor
Noradrenaline tartrate
T20173
Synonym: NSC 169106,NSC-169106,l-Noradrenaline d-bitartrate,NSC169106,Norepinephrine bitartrate
Target:
Glycocyamine
T4238
Synonym: 2-Guanidinoacetic acid,Guanidoacetic acid
Target: Others, Endogenous Metabolite
Cirsimaritin
TQ0119
Synonym:
Target: GABA Receptor
DL-Mannitol
T4959
Synonym: Mannitol
Target: Others
Glucodigifucoside
TN2430
Synonym:
Target:
SDMA
T7344
Synonym: NG,NG'-Dimethyl-L-arginine,Symmetric dimethylarginine
Target: Endogenous Metabolite
D-Mannitol
T0414
Synonym: Mannite,Mannitol,Osmitrol
Target: Apoptosis, Dehydrogenase, Endogenous Metabolite
N-Acetyl-L-arginine dihydrate
T5289
Synonym: N-Ac-L-arg-OH
Target: Others, Endogenous Metabolite
4-Aminohippuric Acid
T1436
Synonym: p-Aminohippuric acid
Target: Amino Acids and Derivatives, Endogenous Metabolite
Medroxyprogesterone
T5040
Synonym:
Target: Estrogen/progestogen Receptor, Progesterone Receptor
Skimmin
T3869
Synonym: Skimmine
Target: Others
Malic acid
T2S0850
Synonym: E 296,2-Hydroxysuccinic acid,Hydroxybutanedioic acid,FDA 2018,Deoxytetraric acid,Pomalus acid
Target: Others, Endogenous Metabolite
magnolin
T3857
Synonym: (+)-Magnolin
Target: ERK
Angiotensin II human
T7040
Synonym: DRVYIHPF,Angiotensin II,Hypertensin II,Ang II
Target: Apoptosis, RAAS
4-Hydroxychalcone
T3005
Synonym: P-Cinnamoylphenol
Target: Others, NF-κB
Hydrocortisone
T1614
Synonym: Cortisol
Target: Glucocorticoid Receptor, Endogenous Metabolite
Magnesium Lithospermate B
T20793
Synonym: Monomethyl lithospermate B,Lithospermate B
Target: Others
1-Methylguanidine hydrochloride
T4904
Synonym:
Target: Others, Endogenous Metabolite
Aristolactam I
T3S1227
Synonym: Aristolactam,Aristololactam I,Aristololactum
Target: Apoptosis, Caspase
3-Methylxanthine
PDK0014
Synonym:
Target: Endogenous Metabolite
Nitidine chloride
T5S0761
Synonym:
Target: Apoptosis, ERK, FAK, p38 MAPK, NF-κB, Topoisomerase, STAT, Parasite
Morroniside
T3414
Synonym:
Target: Apoptosis, MMP, Pyroptosis
Dracorhodin perchlorate
T2S2043
Synonym: Dracorhodin perochlorate,Dracohodin perochlorate
Target: Apoptosis, Others
(R)-3-Hydroxybutanoic acid
T5248
Synonym:
Target: Others, Endogenous Metabolite
Esculentoside A
T3877
Synonym:
Target: NF-κB, COX
Schisandrol B
T6S1917
Synonym: Gomisin A,TJN-101,Besigomsin,Gamma-Schisandrin,Schizandrol B,Wuweizi alcohol-B
Target: P450, Reactive Oxygen Species, Autophagy
N-Acetyl-L-arginine
T8053
Synonym: Ac-Arg-OH
Target: Endogenous Metabolite
Potassium 1H-indol-3-yl sulfate
T4938
Synonym: Indoxyl sulfate potassium salt,Potassium 3-indoxyl sulfate
Target: AhR, Endogenous Metabolite
(E)-Ligustilide
T13670
Synonym:
Target: Others
Marinobufogenin
TN1912
Synonym: Marinobufagenin
Target: ATPase, EGFR
Ganodermaones B
T72798
Synonym:
Target:
Angulatin K
T83110
Synonym:
Target:
Karounidiol
TN4381
Synonym:
Target: Others
Gum arabic
T11513
Synonym: Arabic gum
Target: Others
L-2-Hydroxyglutaric acid
T13749
Synonym: (S)-2-Hydroxyglutaric acid
Target: Others
Alloisoimperatorin
TN3380
Synonym:
Target: AChR
Ergosterol peroxide
TMA1743
Synonym:
Target: ERK, VEGFR, p38 MAPK, Wnt/beta-catenin, Akt, JAK, CDK, JNK, STAT, Antifection
Englerin A
T38484
Synonym: (-)-Englerin A
Target: TRP/TRPV Channel
Dalbergioidin
TN3753
Synonym:
Target: Tyrosinase, ROS, Akt, PI3K, TGF-beta/Smad

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPJ-00797 LDHB Protein, Human, Recombinant (His) Human E. coli
L-Lactate Dehydrogenase B Chain (LDH-B) is a member of the lactate dehydrogenase family that consists of three members, LDH-A, LDH-B and LDH-C; members of this family function as powerful markers for germ cell tumors. LD...
TMPJ-00724 LDHA Protein, Human, Recombinant (His) Human E. coli
L-Lactate Dehydrogenase A Chain (LDHA) is an enzyme that catalyzes the conversion of L-lactate and NAD+ to pyruvate and NADH in the final step of anaerobic glycolysis. LDHA contains an N-terminal coenzyme binding region,...
TMPJ-00755 CRYAB Protein, Human, Recombinant (His) Human E. coli
α Crystallin B Chain (CRYAB) is a cytoplasmic protein that belongs to the small heat shock protein (HSP20) family. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectiv...
TMPJ-01010 PLA2G16 Protein, Human, Recombinant (His) Human E. coli
Group XVI Phospholipase A1/A2 (PLA2G16) belongs to the H-rev 107 family. PLA2G16 is expressed in a number of human tumors including ovarian carcinomas, lung carcinomas. PLA2G16 is involved in the regulation of differenti...
TMPH-02880 Renalase Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
TMPY-02881 RAGE Protein, Human, Recombinant Human HEK293
Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certai...
TMPY-02927 RAGE Protein, Human, Recombinant (His) Human HEK293
Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certai...
TMPY-02956 Apolipoprotein L/APOL1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
APOL1, also known as apolipoprotein L1, is a minor apoprotein component of HDL (High-density lipoprotein) or 'good cholesterol' which is synthesized in the liver and also in many other tissues, including pancreas, kidney...
TMPY-01735 Carbonic Anhydrase 2 Protein, Human, Recombinant (His) Human E. coli
The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bi...
TMPY-01050 Cadherin 6/CDH6 Protein, Human, Recombinant (His) Human HEK293
Cadherins are a family of calcium-dependent, cell-cell adhesion molecules that play an important morpho regulatory role in a wide variety of tissues. Alterations in cadherin function have been implicated in tumor progres...
TMPY-03014 Osteoactivin/GPNMB Protein, Mouse, Recombinant (His) Mouse HEK293
GPNMB belongs to the PMEL / NMB family, also known as Osteoactivin and Hematopoietic growth factor-inducible neurokinin 1 ( HGFIN ), is a transmembrane glycoprotein that is expressed in numerous cells, including osteocla...
TMPY-00767 Cystatin C Protein, Human, Recombinant (His) Human HEK293
Cystatin C, also known as Cystatin-3 (CST3) is a secreted type 2 cysteine protease inhibitor synthesized in all nucleated cells, has been proposed as a replacement for serum creatinine for the assessment of renal functio...
TMPY-01691 Clusterin Protein, Human, Recombinant (CLU34, His) Human HEK293
Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted prot...
TMPY-01694 Clusterin Protein, Mouse, Recombinant (His) Mouse HEK293
Clusterin, also known as complement-associated protein SP-40, Complement cytolysis inhibitor, Apolipoprotein J, Testosterone-repressed prostate message 2, Aging-associated gene 4 protein, CLU and APOJ, is a secreted prot...
TMPY-00988 Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His) Mouse HEK293
Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells,...
TMPY-00873 Lipocalin-2/LCN2 Protein, Human, Recombinant (His) Human HEK293
Lipocalin-2 (LCN2), also known as neutrophil gelatinase-associated lipocalin (NGAL), is a 25 kDa protein belonging to the lipocalin superfamily. It was initially found in activated neutrophils, however, many other cells,...
TMPY-00665 Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His) Human HEK293
Aminopeptidase N (ANPEP or APN), also known as CD13, is a cell-surface metalloprotease located in the small-intestinal and renal microvillar membrane, as well as other plasma membranes. It belongs to the peptidase M1 fam...
TMPJ-00071 EPO/Erythropoietin Protein, Human, Recombinant (His) Human Human Cells
Erythropoietin (EPO) is a glycoprotein hormone that is principally known for its role in erythropoiesis, where it is responsible for stimulating proliferation and differentiation of erythroid progenitor cells. Erythropoi...
TMPY-00639 EPO/Erythropoietin Protein, Human, Recombinant (hFc) Human HEK293
Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting...
TMPY-00443 EPO/Erythropoietin Protein, Mouse, Recombinant Mouse HEK293
Erythropoietin is a member of the EPO / TPO family. It is a secreted, glycosylated cytokine composed of four alpha helical bundles. Erythropoietin can be found in the plasma and regulates red cell production by promoting...
TMPY-01727 GLA/alpha-Galactosidase A Protein, Human, Recombinant (His) Human HEK293
Alpha-galactosidase A, also known as Alpha-D-galactoside galactohydrolase, Alpha-D-galactosidase A, Melibiase and GLA, is a member of the glycosyl hydrolase 27 family. GLA is used as a long-term enzyme replacement therap...
TMPY-01882 HE4 Protein, Human, Recombinant (His) Human HEK293
WAP four-disulfide core domain protein 2, also known as Epididymal secretory protein E4, Major epididymis-specific protein E4, Putative protease inhibitor WAP5, WFDC2 and HE4, is a secreted protein that contains two WAP ...
TMPY-00853 IL-1RA Protein, Human, Recombinant Human E. coli
Interleukin-1 receptor antagonist (IL-1RA) also known as IL1RN is a member of the interleukin 1 cytokine family. This protein inhibits the activities of interleukin 1, alpha (IL1A), and interleukin 1, beta (IL1B), and mo...
TMPY-04483 IRAK4 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Interleukin-1 receptor-associated kinase 4, also known as Renal carcinoma antigen NY-REN-64, IRAK-4, and IRAK4, is a member of the protein kinase superfamily, TKL Ser/Thr protein kinase family, and Pelle subfamily. IRAK4...
TMPY-01167 E-Selectin/CD62E Protein, Human, Recombinant (His) Human HEK293
E-selectin, also known as endothelial leukocyte adhesion molecule-1 (ELAM-1) and CD62E, is an inducible adhesion molecule that is expressed on the surfaces of stimulated vascular endothelial cells and is sometimes involv...
TMPY-05053 ANGPTL2 Protein, Human, Recombinant (His) Human HEK293
The angiopoietin-like protein (ANGPTL) family is homologous to angiopoietins but does not bind to the Tie2 receptor. The function of ANGPTLs has been elucidated largely in the context of angiogenesis and lipid metabolism...
TMPY-02788 IL-2 Protein, Mouse, Recombinant Mouse E. coli
Interleukin-2, also known as a T-cell growth factor, TCGF, Aldesleukin, and IL2, is a secreted protein that belongs to the IL-2 family. Interleukin-2 / IL-2 was the first interleukin molecule to be discovered. Interleuki...
TMPY-02457 IL-2 Protein, Rat, Recombinant Rat E. coli
Interleukin-2, also known as a T-cell growth factor, TCGF, Aldesleukin, and IL2, is a secreted protein that belongs to the IL-2 family. Interleukin-2 / IL-2 was the first interleukin molecule to be discovered. Interleuki...
TMPH-02270 Tyrosinase/TYR Protein, Human, Recombinant (His & SUMO) Human E. coli
Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient. Plays an essential rol...
TMPY-01675 RAGE Protein, Mouse, Recombinant (His) Mouse HEK293
Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certai...
TMPY-01716 RAGE Protein, Human, Recombinant (hFc) Human HEK293
Receptor for Advanced Glycosylation End Products (RAGE, or AGER) is a member of the immunoglobulin super-family transmembrane proteins, as a signal transduction receptor which binds advanced glycation endproducts, certai...
TMPJ-00504 Serpin A8 Protein, Human, Recombinant (His) Human Human Cells
Angiotensinogen is involved in maintaining blood pressure and in the pathogenesis of essential hypertension and preeclampsia. Genetic variations in Angiotensinogen are associated with susceptibility to essential hyperten...
TMPY-00089 TMIGD1 Protein, Human, Recombinant (His) Human HEK293
The transmembrane and immunoglobulin domain-containing 1 (TMIGD1) is a novel tumor suppressor that is highly expressed in normal renal tubular epithelial cells, but it is downregulated in human renal cancer. TMIGD1 is a ...
TMPK-00526 LRG1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Diabetic nephropathy (DN) is an important public health concern of increasing proportions and the leading cause of end-stage renal disease (ESRD) in diabetic patients. It is one of the most common long-term microvascular...
TMPY-04872 TMIGD1 Protein, Human, Recombinant (mFc) Human HEK293
The transmembrane and immunoglobulin domain-containing 1 (TMIGD1) is a novel tumor suppressor that is highly expressed in normal renal tubular epithelial cells, but it is downregulated in human renal cancer. TMIGD1 is a ...
TMPK-01128 LRG1 Protein, Mouse, Recombinant (His) Mouse HEK293
Diabetic nephropathy (DN) is an important public health concern of increasing proportions and the leading cause of end-stage renal disease (ESRD) in diabetic patients. It is one of the most common long-term microvascular...
TMPH-02818 Osteocalcin Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption.
TMPH-02743 Klk1b5 Protein, Mouse, Recombinant (His & SUMO) Mouse E. coli
Data support a completely novel mechanism in which miR-382 targets kallikrein 5 and contributes to the development of renal inner medullary interstitial fibrosis. PMID: 22202692
TMPH-00269 GPR52 Protein, Bovine, Recombinant (His & KSI) Bovine E. coli
Data support a completely novel mechanism in which miR-382 targets kallikrein 5 and contributes to the development of renal inner medullary interstitial fibrosis. PMID: 22202692
TMPH-03018 MeTAP1 Protein, Mycobacterium tuberculosis, Recombinant (His) Mycobacterium tuberculosis E. coli
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
TMPH-02191 Tetraspanin-2/TSPAN2 Protein, Human, Recombinant Human E. coli
PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
TMPH-03269 COMMD5 Protein, Rat, Recombinant (His & Myc) Rat E. coli
Hcarg localizes to the rat chromosome 7 between the markers Mit3 and Mit4. We identified a BglII RFLP between BN.lx and SHR rats. PMID: 11871861 HCaRG regulates renal epithelial cell growth and differentiation causing G(...
TMPJ-00931 Serpin A4 Protein, Human, Recombinant (His) Human Human Cells
Serpin Peptidase Inhibitor, Clade A (α-1 Antiproteinase, Antitrypsin), Member 4 (Serpin A4) is a member of the Serpin family. Serpin A4 exists as a monomer and some homodimers. Serpin A4 is expressed by the liver and sec...
TMPH-01456 Human herpesvirus 6B (HHV-6 variant B) (strain Z29) Glycoprotein Q1 (His & Myc) HHV-6B E. coli
Multiligand endocytic receptor. Acts together with CUBN to mediate endocytosis of high-density lipoproteins. Mediates receptor-mediated uptake of polybasic drugs such as aprotinin, aminoglycosides and polymyxin B. In the...
TMPY-03460 DCXR Protein, Human, Recombinant (His) Human E. coli
DCXR, also known as HCR2, belongs to the short-chain dehydrogenases/reductases (SDR) family. It is highly expressed in kidney, liver and epididymis. In the epididymis, DCXR is mainly expressed in the proximal and dist...
TMPY-02111 Carbonic Anhydrase 2 Protein, Mouse, Recombinant (His) Mouse E. coli
The carbonic anhydrases (or carbonate dehydratases) are classified as metalloenzyme for its zinc ion prosthetic group and form a family of enzymes that catalyze the rapid interconversion of carbon dioxide and water to bi...
TMPY-02418 Kynureninase/KYNU Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
KYNU (Kynureninase) is a Protein Coding gene. KYNU is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranili...
TMPY-02479 Kynureninase/KYNU Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
KYNU (Kynureninase) is a Protein Coding gene. KYNU is a pyridoxal-5'-phosphate (pyridoxal-P) dependent enzyme that catalyzes the cleavage of L-kynurenine and L-3-hydroxykynurenine into anthranilic and 3-hydroxyanthranili...
TMPY-02931 Cadherin 6/CDH6 Protein, Mouse, Recombinant (His) Mouse HEK293
Cadherins are a family of calcium-dependent, cell-cell adhesion molecules that play an important morpho regulatory role in a wide variety of tissues. Alterations in cadherin function have been implicated in tumor progres...
TMPH-01695 MLKL Protein, Human, Recombinant (His) Human Yeast
Component of a heteromeric calcium-permeable ion channel formed by PKD1 and PKD2 that is activated by interaction between PKD1 and a Wnt family member, such as WNT3A and WNT9B. Both PKD1 and PKD2 are required for channel...
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LDHB Protein, Human, Recombinant (His)
TMPJ-00797
Species: Human
Expression System: E. coli
LDHA Protein, Human, Recombinant (His)
TMPJ-00724
Species: Human
Expression System: E. coli
CRYAB Protein, Human, Recombinant (His)
TMPJ-00755
Species: Human
Expression System: E. coli
PLA2G16 Protein, Human, Recombinant (His)
TMPJ-01010
Species: Human
Expression System: E. coli
Renalase Protein, Mouse, Recombinant (His & SUMO)
TMPH-02880
Species: Mouse
Expression System: E. coli
RAGE Protein, Human, Recombinant
TMPY-02881
Species: Human
Expression System: HEK293
RAGE Protein, Human, Recombinant (His)
TMPY-02927
Species: Human
Expression System: HEK293
Apolipoprotein L/APOL1 Protein, Human, Recombinant (His)
TMPY-02956
Species: Human
Expression System: Baculovirus-Insect Cells
Carbonic Anhydrase 2 Protein, Human, Recombinant (His)
TMPY-01735
Species: Human
Expression System: E. coli
Cadherin 6/CDH6 Protein, Human, Recombinant (His)
TMPY-01050
Species: Human
Expression System: HEK293
Osteoactivin/GPNMB Protein, Mouse, Recombinant (His)
TMPY-03014
Species: Mouse
Expression System: HEK293
Cystatin C Protein, Human, Recombinant (His)
TMPY-00767
Species: Human
Expression System: HEK293
Clusterin Protein, Human, Recombinant (CLU34, His)
TMPY-01691
Species: Human
Expression System: HEK293
Clusterin Protein, Mouse, Recombinant (His)
TMPY-01694
Species: Mouse
Expression System: HEK293
Lipocalin-2/LCN2 Protein, Mouse, Recombinant (His)
TMPY-00988
Species: Mouse
Expression System: HEK293
Lipocalin-2/LCN2 Protein, Human, Recombinant (His)
TMPY-00873
Species: Human
Expression System: HEK293
Aminopeptidase N/CD13 Protein, Human, Recombinant (I603M, His)
TMPY-00665
Species: Human
Expression System: HEK293
EPO/Erythropoietin Protein, Human, Recombinant (His)
TMPJ-00071
Species: Human
Expression System: Human Cells
EPO/Erythropoietin Protein, Human, Recombinant (hFc)
TMPY-00639
Species: Human
Expression System: HEK293
EPO/Erythropoietin Protein, Mouse, Recombinant
TMPY-00443
Species: Mouse
Expression System: HEK293
GLA/alpha-Galactosidase A Protein, Human, Recombinant (His)
TMPY-01727
Species: Human
Expression System: HEK293
HE4 Protein, Human, Recombinant (His)
TMPY-01882
Species: Human
Expression System: HEK293
IL-1RA Protein, Human, Recombinant
TMPY-00853
Species: Human
Expression System: E. coli
IRAK4 Protein, Human, Recombinant (His)
TMPY-04483
Species: Human
Expression System: Baculovirus-Insect Cells
E-Selectin/CD62E Protein, Human, Recombinant (His)
TMPY-01167
Species: Human
Expression System: HEK293
ANGPTL2 Protein, Human, Recombinant (His)
TMPY-05053
Species: Human
Expression System: HEK293
IL-2 Protein, Mouse, Recombinant
TMPY-02788
Species: Mouse
Expression System: E. coli
IL-2 Protein, Rat, Recombinant
TMPY-02457
Species: Rat
Expression System: E. coli
Tyrosinase/TYR Protein, Human, Recombinant (His & SUMO)
TMPH-02270
Species: Human
Expression System: E. coli
RAGE Protein, Mouse, Recombinant (His)
TMPY-01675
Species: Mouse
Expression System: HEK293
RAGE Protein, Human, Recombinant (hFc)
TMPY-01716
Species: Human
Expression System: HEK293
Serpin A8 Protein, Human, Recombinant (His)
TMPJ-00504
Species: Human
Expression System: Human Cells
TMIGD1 Protein, Human, Recombinant (His)
TMPY-00089
Species: Human
Expression System: HEK293
LRG1 Protein, Cynomolgus, Recombinant (His)
TMPK-00526
Species: Cynomolgus
Expression System: HEK293
TMIGD1 Protein, Human, Recombinant (mFc)
TMPY-04872
Species: Human
Expression System: HEK293
LRG1 Protein, Mouse, Recombinant (His)
TMPK-01128
Species: Mouse
Expression System: HEK293
Osteocalcin Protein, Mouse, Recombinant (His & SUMO)
TMPH-02818
Species: Mouse
Expression System: E. coli
Klk1b5 Protein, Mouse, Recombinant (His & SUMO)
TMPH-02743
Species: Mouse
Expression System: E. coli
GPR52 Protein, Bovine, Recombinant (His & KSI)
TMPH-00269
Species: Bovine
Expression System: E. coli
MeTAP1 Protein, Mycobacterium tuberculosis, Recombinant (His)
TMPH-03018
Species: Mycobacterium tuberculosis
Expression System: E. coli
Tetraspanin-2/TSPAN2 Protein, Human, Recombinant
TMPH-02191
Species: Human
Expression System: E. coli
COMMD5 Protein, Rat, Recombinant (His & Myc)
TMPH-03269
Species: Rat
Expression System: E. coli
Serpin A4 Protein, Human, Recombinant (His)
TMPJ-00931
Species: Human
Expression System: Human Cells
Human herpesvirus 6B (HHV-6 variant B) (strain Z29) Glycoprotein Q1 (His & Myc)
TMPH-01456
Species: HHV-6B
Expression System: E. coli
DCXR Protein, Human, Recombinant (His)
TMPY-03460
Species: Human
Expression System: E. coli
Carbonic Anhydrase 2 Protein, Mouse, Recombinant (His)
TMPY-02111
Species: Mouse
Expression System: E. coli
kynureninase/KYNU Protein, Mouse, Recombinant (His)
TMPY-02418
Species: Mouse
Expression System: Baculovirus-Insect Cells
kynureninase/KYNU Protein, Human, Recombinant (His)
TMPY-02479
Species: Human
Expression System: Baculovirus-Insect Cells
Cadherin 6/CDH6 Protein, Mouse, Recombinant (His)
TMPY-02931
Species: Mouse
Expression System: HEK293
MLKL Protein, Human, Recombinant (His)
TMPH-01695
Species: Human
Expression System: Yeast
Cat No. Product Name
L8700 Ferroptosis Compound Library

800 compounds
A unique collection of 800 ferroptosis signaling pathway related compounds, a powerful tool for new target identification, drug discovery, and mechanism study;
TargetMol