adp

Prasugrel (CS-747) is a piperazine derivative and PLATELET AGGREGATION INHIBITOR that is used to prevent THROMBOSIS in patients with ACUTE CORONARY SYNDROME; UNSTABLE ANGINA and MYOCARDIAL INFARCTION, as well as in those undergoing PERCUTANEOUS CORONARY INTERVENTIONS.

Adenosine 5'-diphosphate (ADP) is a naturally occurring nucleotide derived from the dephosphorylation of ATP. Adenosine 5'-diphosphate is essential for cellular metabolism and induces platelet aggregation.

Tirofiban(MK383) hydrochloride monohydrate is a non-peptide glycoprotein IIb/IIIa antagonist.

Limaprost (17α,20-dimethyl-δ2-PGE1) is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency.It is a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost (17α,20-dimethyl-δ2-PGE1) can be used for pain relief, has antianginal effects, and has potential for ischaemic symptoms treatment.

Ticlopidine (PCR 5332) is an antiplatelet drug in the thienopyridine family which is an adenosine diphosphate (ADP) receptor inhibitor.

Cyclic ADP-ribose (cADPR) is an effective calcium mobilization second messenger synthesized from NAD+ by ADP-ribosyl cyclase. It mainly increases cytosolic calcium through Ryanodine receptor-mediated endoplasmic reticulum release and extracellular influx via the opening of TRPM2 channels.

2-Chloro-ADP (2-Chloroadenosine 5′-diphosphate) is a derivative of Adenosine 5'-diphosphate (ADP) that induces platelet aggregation and inhibits stimulated adenylate cyclase. Additionally, 2-Chloro-ADP can inhibit the nucleotide-binding domain (NBD) of Mortalin with a Ki value of 45.05 μM.

ADP-β-S (trisodium) is an analog of ADP and acts as a partial agonist. It can induce human platelet aggregation and inhibit PGE1-stimulated adenylate cyclase.

ADP-ribose/PARP-IN-1 (Compound Ex.16) is a conjugated compound composed of a disease-targeting segment, a PARP inhibitor section, a cleavable linker, and a chelating agent. It targets specific sites via its disease-targeting part, delivering the PARP inhibitor selectively to tumor cells. Under suitable conditions, the cleavable linker releases the PARP inhibitor to hinder DNA damage repair by inhibiting PARP, while the chelating agent transports a radionuclide for cytotoxic action. This compound is applicable in prostate cancer research.

6-Bn-ADP (N6-benzyl ADP) sodium is a derivative of Adenosine 5'-diphosphate (ADP) that inhibits ATP hydrolysis. It also suppresses the ATPase activity of the proteins Mortalin, Hsc70, and Hsp70, with Ki values of 86.51 μM, 294.5 μM, and 1612 μM, respectively.

Cyclic ADP-ribose diammonium (cADPR diammonium) serves as a potent calcium mobilization second messenger, synthesized from NAD+ by ADP-ribosyl cyclase. It primarily enhances cytosolic calcium levels by triggering release from the endoplasmic reticulum via Ryanodine receptors, and by facilitating extracellular influx through TRPM2 channels.

2-Fluoro-ADP is a bioactive chemical.

ADP-2341 is a soluble analog of FiVe1.

ADP-Ribosylarginine can regulate cell proliferation and tumorigenesis.

ADP-Glucose (ADPG) is an immediate precursor used in the biosynthesis, by glucose addition, of storage polysaccharides in plants, green algae, and cyanobacteria, as well as structural polysaccharides in certain bacteria.[1],[2] It is used by amylose synthases or starch synthases in plastids in the production of amylose, amylopectins, starch, and other polysaccharides. ADPG is normally generated within plastids, although it can be biosynthesized in the cytoplasm of certain grasses and imported into plastids by a membrane-bound transporter.[3]

Cyclic ADP-Ribose (ammonium salt) (cADPR) is an endogenous NAD⁺ metabolite that triggers Ca²⁺ release from ER stores via ryanodine receptors and is synthesized by CD38 and CD157. It may also activate TRPM2 in a temperature-dependent manner. Showing potential in research related in inflammation and immunology.

Cyclic ADP-ribose ammonium (cADPR ammonium) is a potent calcium mobilization second messenger synthesized from NAD+ by ADP-ribosyl cyclase. It raises cytosolic calcium levels through Ryanodine receptor-mediated release from the endoplasmic reticulum and facilitates extracellular influx via TRPM2 channels [1][2][3].

8-Azido-ADP (disodium) is a covalently bound inhibitor of mitochondrial adenine nucleotide translocation that prevents the ADP-induced 4 to 3 shift in mitochondrial respiration. Additionally, in a light-dependent reaction, 8-Azido-ADP (disodium) irreversibly inhibits adenine nucleotide exchange.

2'-Deoxy-3',5'-ADP (pdAp) is a monomer used in nucleic acid synthesis.

8-Azido-ADP (sodium) is a derivative of ATP precursor and purine receptor ligand ADP that can undergo click chemistry reactions.

ADP-ribose pyrophosphatase is an enzyme that catalyzes the hydrolysis of ADP-ribose into AMP and ribose 5-phosphate.

2′-OMe-ADP is a nucleotide analogue used in oligonucleotide synthesis.

2'-F-ADP is a nucleotide analogue employed in the synthesis of oligonucleotides.

N6-4-aminobutyl-ADP (6-AB-ADP) trisodium is an ADP derivative that serves as a nucleotide analog or conjugating agent. It is used for labeling enzyme substrates, such as kinases, constructing biological probes, or functionalizing nucleotide chains.