acat — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T10503	ACAT-IN-1 cis isomer		Acyltransferase
	ACAT-IN-1 cis isomer is a potent ACAT inhibitor (IC50: 100 nM) for the study of immune system-related diseases.		Acyltransferase
T40553	ACAT-IN-6
	ACAT-IN-6, an acyl-Coenzyme A: cholesterol acyltransferase (ACAT) inhibitor, displays potent inhibition of NF-κB mediated transcription.
T39415	ACAT-IN-9
	ACAT-IN-9, acts as an inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT). By doing so, it effectively suppresses NF-κB mediated transcription.
T39414	ACAT-IN-7
	ACAT-IN-7 is a compound that acts as an inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT) enzyme. It effectively suppresses the transcription process mediated by NF-κB.
T39412	ACAT-IN-5
	ACAT-IN-5 (example 19) is a compound that functions as an inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT). By inhibiting ACAT, this compound effectively suppresses the transcription mediated by NF-κB.
T40551	ACAT-IN-3
	ACAT-IN-3, a potent inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT), effectively suppresses NF-κB dependent transcription.
T40552	ACAT-IN-10
	ACAT-IN-10 is an acyl-Coenzyme A: cholesterol acyltransferase (ACAT) inhibitor. It inhibits NF-κB mediated transcription with a weak activity.
T40554	ACAT-IN-4
	ACAT-IN-4 (Example 208) is a chemical compound that functions as an inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT). Additionally, ACAT-IN-4 effectively inhibits the transcription process mediated by NF-...
T39417	ACAT-IN-2
	ACAT-IN-2 is a potent inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT). This compound effectively blocks NF-κB mediated transcription.
T39413	ACAT-IN-8
	ACAT-IN-8 (example 206) is a compound that functions as an inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT), an enzyme involved in cholesterol modulation. This compound also possesses the ability to inhib...
T39411	ACAT-IN-10 dihydrochloride
	ACAT-IN-10 dihydrochloride is a compound that serves as an inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT).ACAT-IN-10 dihydrochloride effectively hampers NF-κB mediated transcription, albeit to a lesser ...
T39416	ACAT-IN-4 hydrochloride
	ACAT-IN-4 hydrochloride (Example 208) is a hydrochloride salt of a potent inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT). This compound effectively hinders NF-κB mediated transcription.
T22665	PD 128042	CI 976	Acyltransferase
	PD 128042 (CI 976) is a potent orally active and selective ACAT inhibitor(IC50: 73 nM) and a potent lysophospholipid acyltransferase(LPAT) inhibitor. CI 976 inhibits Golgi-associated LPAT activity (IC50: 15 μM) and multi...		Acyltransferase
T2753	Avasimibe	PD-148515,CI-1011	P450 , Acyltransferase
	Avasimibe (PD-148515) is an orally bioavailable inhibitor of acyl-Coenzyme A: cholesterol acyltransferase (ACAT, IC50: 3.3 μM) that prevents cholesterol deposition in the arterial wall. It also inhibits human P450 isoenz...		P450 , Acyltransferase
T1239	Indacaterol maleate	QAB149	Adrenergic Receptor
	Indacaterol maleate (QAB149) is an ultra-long-acting β-adrenoceptor agonist.		Adrenergic Receptor
T2320	Indacaterol		Adrenergic Receptor
	Indacaterol (Onbrez; Arcapta) is a β2-Adrenergic Agonist. The mechanism of action of indacaterol is as an Adrenergic beta2-Agonist.		Adrenergic Receptor
T6078	Saracatinib	AZD0530	EGFR , Src , BTK , Autophagy
	Saracatinib (AZD0530) (AZD0530) is an effective Src inhibitor (IC50: 2.7 nM), and effective to Lck, Fyn, Lyn, Blk, Fgr and c-Yes.		EGFR , Src , BTK , Autophagy
T6035	Odanacatib	MK-0822	Cysteine Protease
	Odanacatib is an inhibitor of cathepsin K with potential anti-osteoporotic activity.		Cysteine Protease
T8010	Dibutyl sebacate	Dibutyl decanedioate	Others
	Dibutyl sebacate (Dibutyl decanedioate) is an organic chemical which is mainly used as a plasticizer in the production of plastics.		Others
T26548	Acaterin
	Acaterin, an inhibitor of acyl-CoA: cholesterol acyltransferase (ACAT), inhibits synthesis of cholesteryl ester in macrophage J774.