ec-1

Afatinib (BIBW 2992) is an irreversible inhibitor of the EGFR family (EGFR-wt, EGFR-L858R, EGFR-L858R T790M, and HER2) with IC50s of 0.5 nM, 0.4 nM, 10 nM, and 14 nM, respectively.

Dodec-1-ene is toxic to MIAPaCa2 cells, Pseudokirchneriella subcapitata, and Daphnia magna. Dodec-1-enehas antibacterial activity and can be used in the synthesis of surfactants.

EC-17 (disodium salt), a folate receptor alpha (FRα) targeting contrast agent, exhibits fluorescent properties within the visible light spectrum, characterized by peak excitation and emission wavelengths of 470 520 nm, respectively.

Undec-1-Ene is an alkene widely used in biochemical experiments and drug synthesis research.

EC17 is a FITC conjugated folic acid, also known as Folate-FITC. It also acts as an FRα-targeting agent that fluoresces at 500nm. EC17 is a conjugate consisting of fluorescein isothiocyanate (FITC) conjugated with folate with potential antineoplastic acti

Dec-1-enylsuccinic acid is a biochemical.

EC-19 induces differentiation of EC cells and directs the formation of epithelial-like derivatives.

SLEC-11 emerged as a synthetic lethal(SL) lead in E-cadherin-deficient cells which has potential for the treatment of gastric cancer.

2,2,3,3-Tetramethyl-4,7,10,13,16-pentaoxa-3-silanonadec-18-yne is a useful organic compound for research related to life sciences and the catalog number is T64752.

Isopropyl dodec-11-enylfluorophosphonate (IDEFP) is an organophosphorus ester that serves as a central cannabinoid receptor (CB1) antagonist and equally inhibits fatty acid amide hydrolase (FAAH), both with an IC50 value of 2 nM [1].

Tert-butyl undec-10-enoate (Tert-Butyl 10-undecenoate) is an organic synthesis intermediate.

(E)-hexadec-11-en-1-ol ((E)-11-Hexadecenol) is the pheromone of the spotted stem borer Chilo partellus. It is a long-chain fatty acid found in the volatile oil of Daphne genkwa and has potential antibacterial activity.

(Z)-Tetradec-12-en-1-yl acetate (cis-12-Tetradecenylacetate) is a pheromone of the corn borer.

(E)-tetradec-12-enyl acetate (12E-Tetradecenyl acetate) is a synthetic surfactant and a pheromone of the corn borer, commonly used in the chemical industry.

(E)-1-(4-Hydroxyphenyl)dec-1-en-3-one is a natural product for research related to life sciences. The catalog number is TN3905 and the CAS number is 958631-84-0.

EC-1456 is a folate-microtubule targeting agent that exhibits significant antiproliferative activity against folate receptor (FR) positive tumors, including models resistant to anticancer drugs. EC-1456 is utilized in cancer research.

N-3-oxo-Hexadec-11Z-enoyl-L-homoserine lactone is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.

Sp-cAMPS sodium salt is an analog of cAMP that serves as a potent activator of cAMP-dependent PKA I and PKA II, and as a competitive phosphodiesterase (PDE3A) inhibitor with a Ki of 47.6 μM. It also binds the PDE10 GAF domain with an EC50 of 40 μM [1] [2] [3].

Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity towards 5-HT 2C receptors while acting as an antagonist for 5-HT 2B receptors, with respective potency values of EC 50 = 32 μM and IC 50 = 27 μM. Its primary mechanism of action involves the modulation of serotonergic and noradrenergic pathways. Viloxazine is commonly employed in depression research [1] [2].

(Rac)-EC5026 ((Rac)-BPN-19186) is a potent piperidine inhibitor of soluble epoxide hydrolase (sEH) with a Ki of 0.06 nM, useful for research on Parkinson's disease and dementia with Lewy Bodies (DLB) [1].

Afatinib Dimaleate (BIBW 2992MA2) is an orally bioavailable anilino-quinazoline derivative and inhibitor of the receptor tyrosine kinase (RTK) epidermal growth factor receptor (ErbB; EGFR) family, with antineoplastic activity.

GW3965 is a potent and selective agonist of liver X receptor (LXR) with EC50 values of 190 nM for hLXRα and 30 nM for hLXRβ [1] [2] [3].

Pyrimorph is a fungicide with high activity against the plant pathogen Phytophthora capsici. Pyrimorph inhibited different stages in the life cycle of P. capsici including mycelial growth, sporangium production, zoospore release, and cystospore germination with EC(50) values of 1.84, 0.17, 4.92, and 0.09 microg mL(-1), respectively.

FEN1-IN-3 is a human flap endonuclease-1 ( hFEN1 ) inhibitor that stabilizes hFEN1 with an EC 50 of 6.8 μM .