c-11

C-11 is a tubulin inhibitor and functions as an ADC cytotoxin, exhibiting cytotoxicity for carcinoma cell lines.

Levetimide C-11 is a radiotracer.

MBC-11 is a first-in-class conjugate of the bone-targeting bisphosphonate etidronate covalently linked to the antimetabolite cytarabine (araC), with potential to treat tumor-induced bone disease (TIBD).

Boc-11-aminoundecanoic acid is an alkyl ether-based PROTAC linker used in the synthesis of [MS432].

SBC-115076 is a potent extracellular proprotein convertase subtilisin kexin type 9 (PCSK9) antagonist.

MBC-11 trisodium has potential to treat tumor-induced bone disease (TIBD).It is a first-in-class conjugate of the bone-targeting bisphosphonate HEDP covalently linked to the antimetabolite Ara-C.

11-Methoxyuncarine C is a useful organic compound for research related to life sciences and the catalog number is T124542.

JHU-75528 C-11 can be used as a Radiotracer for PET Imaging of CB1 Cannabinoid Receptors.

c-Met-IN-11 is a potent inhibitor of c-MET (IC50: 41.4 nM) and VEGFR-2 (IC50: 71.1 nM).

c-Myc inhibitor 11 (Compound 67e), a c-MYC inhibitor (p EC 50: 6.4), demonstrates high clearance, moderate volume of distribution, and a short half-life in rat pharmacokinetic assays, making it suitable for cancer research [1].

Glutaminase C Inhibitor 11 is a potent inhibitor specifically targeting Glutaminase C (GAC), demonstrating significant inhibition of GAC enzyme activity with an EC50 value of 10.64 nM. It effectively diminishes the viability of A549 non-small cell lung cancer (NSCLC) cells, presenting an IC50 of 4.025 nM. Moreover, at concentrations of 0.1 and 1 µM, it substantially impedes colony formation and reduces intracellular glutamate levels in A549 cells. Demonstrating efficacy in vivo, Glutaminase C Inhibitor 11 at a dosage of 100 mg/kg markedly curtails tumor growth in an A549 mouse xenograft model.

C-HEGA-11 is a useful organic compound for research related to life sciences. The catalog number is TF0102 and the CAS number is 864434-16-2.

MBC-11 triethylamine has potential to treat tumor-induced bone disease (TIBD), is a first-in-class conjugate of the bone-targeting bisphosphonate etidronate covalently linked to the antimetabolite cytarabine (araC).

UC-112 is a novel, potent IAP inhibitor that effectively inhibits cell growth in two human melanoma and two human prostate cancer cell lines (IC50=0.7-3.4 uM).

CP-LC-1143 is an ionizable cationic amino lipid employed for the delivery of various RNA forms, including mRNA, cRNA, and saRNA.

FAUC-113 is an antagonist of Dopamine D4 receptor.

AC-119 is a bamifylline metabolite in human plasma. It has been shown to induce apoptosis in cancer cells while having no effect on health cells in humans.

LNC-119 is an aminosteroid.

CC-115 is a inhibitor of mTOR DNA-PK (IC50= 21 13 nM).

SBC-110736 is an inhibitor of proprotein convertase subtilisin kexin type 9 (PCSK9).

SLEC-11 emerged as a synthetic lethal(SL) lead in E-cadherin-deficient cells which has potential for the treatment of gastric cancer.

CC-115 hydrochloride is a potent dual inhibitor of DNA-PK (IC50 = 13 nM) and mTOR kinase (IC50 = 21 nM), effectively blocking both mTORC1 and mTORC2 signaling pathways.

CYC116 is a potent inhibitor of Aurora A B with Ki of 8.0 nM 9.2 nM, is less potent to VEGFR2 (Ki of 44 nM), with 50-fold greater potency than CDKs, not active against PKA, Akt PKB, PKC, no effect on GSK-3α β, CK2, Plk1 and SAPK2A. Phase 1.

CGC-11047 free base is a second generation polyamine analogue of N1, N12-bisethylspermine (BESpm).