Search Result

Search Results for " proteasome "

Targets

Libraries

Ubiquitination Compound Library Protease Inhibitor Library HIF-1 Signaling Pathway Compound Library NF-κB Signaling Compound Library

------------------------More------------------------

Compounds

Cat No.	Product Name
T21854	Proteasome inhibitor IX	PS-IX,AM114	Proteasome
	AM 114 is an inhibitor of chymotrypsin-like activity of the 20S proteasome (IC50 ~1 μM). AM 114 shows potent anticancer ...		Proteasome
T63321	20S Proteasome activator 1		Proteasome
	20S Proteasome activator 1 is a 20S proteasome activator with IC50 of 0.3 μM for trypsin-like sites, 0.7 μM for chymotry...		Proteasome
T12561	Proteasome-IN-1		Proteasome
	Proteasome-IN-1 is an inhibitor of proteasome.		Proteasome
T71092	Proteasome-IN-3
	Proteasome-IN-3 is an inhibitor of proteasome-associated DUBs.
T72762	Proteasome-IN-4
	Proteasome-IN-4 is an excellent and non-covalent proteasome inhibitor ( IC 50 =8.39 nM). Proteasome-IN-4 has potent anti...
T62255	20S Proteasome-IN-4
	20S Proteasome-IN-4 (Compound 7) is a brain-penetrant, parasite-selective, orally active 20S proteasome inhibitor with a...
T76243	Proteasome-activating peptide 1 TFA
	Proteasome-activating peptide 1 TFA is a peptide and a potent proteasome activator. Proteasome-activating peptide 1 TFA ...
T9710	Dazcapistat		Cysteine Protease
	Dazcapistat is a potent calpain inhibitor, with IC50s of <3 μM for calpain 1, calpain 2 and calpain 9, respectively.		Cysteine Protease
T9090	MUN57694		Proteasome
	MUN57694 is an inhibitor of 26S proteasome.		Proteasome
T6432	Calpeptin		Apoptosis , Cysteine Protease , Proteasome
	Calpeptin is a potent, cell-permeable calpain inhibitor.		Apoptosis , Cysteine Protease , Proteasome
T13858	RA190		Proteasome
	RA190 inhibits proteasome function by covalently binding to cysteine 88 of ubiquitin receptor RPN13.		Proteasome
T7016	VR23		Caspase , Apoptosis , Proteasome
	VR23 is a potent proteasome inhibitor. Data shows IC50 =1 nM for trypsin-like proteasomes, IC50=50-100 nM for chymotryps...		Caspase , Apoptosis , Proteasome
T2470	MDL-28170	Calpain Inhibitor III	Cysteine Protease , Proteasome
	Calpain Inhibitor III is a Cysteine protease.		Cysteine Protease , Proteasome
T2122	Ixazomib	MLN2238	Caspase , Proteasome , Autophagy
	MLN2238, a second generation, boron-containing peptide proteasome inhibitor (PI), inhibits the chymotrypsin-like proteol...		Caspase , Proteasome , Autophagy
T8978	DD1	HUN85111,3,3'-Diamino-4'-methoxyflavone	Proteasome
	DD1 is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.		Proteasome
T1795	Carfilzomib	PR-171	Proteasome , Apoptosis , Autophagy
	Carfilzomib is an irreversible proteasome inhibitor and antineoplastic agent that is used in treatment of refractory mul...		Proteasome , Apoptosis , Autophagy
T3786	Tomatine	lycopersicin	Apoptosis , Proteasome
	An antiproliferatve agent of breast adenocarcinoma cells.		Apoptosis , Proteasome
T7814	Alloxan monohydrate		Proteasome
	Alloxan Monohydrate is a glucose analog used to induce diabetes by destroying beta-cells.		Proteasome
T0372	Gabexate mesylate	FOY	Serine Protease , Proteasome , Factor Xa
	Gabexate mesylate is a serine proteinase inhibitor used therapeutically in the treatment of pancreatitis, disseminated i...		Serine Protease , Proteasome , Factor Xa
T3028	Tripterin	Celastrol,Tripterine	Autophagy , Proteasome , Mitophagy , Apoptosis
	Celastrol is an effective proteasome inhibitor for the chymotrypsin-like activity of a purified 20S proteasome(IC50=2.5 ...		Autophagy , Proteasome , Mitophagy , Apoptosis