Soluble

Soluble epoxide hydrolase inhibitor is a soluble epoxide hydrolase inhibitor (human soluble epoxide hydrolase (h-sEH) with pIC50 of 8.4).

Soluble epoxide hydrolase (sEH) PROTAC 1a is a proteolysis-targeting chimera (PROTAC) comprising a cereblon ligand linked to the sEH inhibitor t-TUCB via a linker, promoting selective sEH degradation and inhibiting its hydrolase activity (IC50 = 0.8 nM) significantly more than its phosphatase activity (IC50 = >10,000 nM). This compound preferentially targets cytosolic sEH for lysosomal rather than proteasomal degradation. Furthermore, it mitigates thapsigargin-induced upregulation of phosphorylated inositol-requiring enzyme 1α (IRE1α) and X-box binding protein 1 (XBP1) splicing in HepG2 and 293T cells, thereby reducing endoplasmic reticulum stress.

Cholesterol (Water Soluble) is a water-soluble cholesterol preparation used in experimental studies to investigate the specific effects of cholesterol enrichment or depletion on the biophysical properties and functional characteristics of inner hair cells (IHCs) with regard to potassium currents. As an essential component of the plasma membrane, cholesterol has the ability to modulate the activity and kinetics of ion channels embedded in the lipid bilayer. (Note: This product is a mixture of cholesterol and methyl-β-cyclodextrin.)

EC5026 (BPN-19186) has the potential to relieve pain by stabilizing natural analgesic and anti-inflammatory mediators.

BI-1935 is an inhibitor of soluble epoxide hydrolase (sEH). For diseases related to cardiovascular disease.

CUDA is an effective soluble cyclohydrolase inhibitor with IC50 of 11.1 nM and 112 nM for mouse sEH and human sEH, respectively. CUDA selectively increases the activity of peroxisome proliferator-activated receptor (PPAR) alpha. CUDA may be valuable for the study of cardiovascular diseases.

Oleuropeinic acid, initially present in olive tissues or produced through the thermal oxidation of oleuropein, is an antioxidant-soluble fiber.

trans-AUCB (t-AUCB) is an effective and selective soluble epoxide hydrolase inhibitor, with IC50 values of 1.3 nM for hsEH, 8 nM for mouse sEH, and 8 nM for rat sEH.

Ataciguat (HMR-1766) (HMR-1766) is a potent and specific soluble guanylate cyclase (sGC) activator.

BAY 41-8543 is a nitric oxide (NO)-independent stimulator of soluble guanylyl cyclase (sGC).

AUDA is an inhibitor of sEH(IC50 values of 18 and 69 nM for the mouse and human enzymes, respectively)

Vazegepant hydrochloride (Vazegepant HCl) is the first intranasal gepant for the acute treatment of migraine and has announced a positive phase II/III study.

Biotin (Vitamin H) is a water-soluble B-vitamin and is necessary for cell growth, the production of fatty acids, and the metabolism of fats and amino acids.

N-(3-methoxybenzyl)-octadecanamide deverts from Maca (Lepidium meyenii Walp.).

MGV354 is a soluble activator of guanylate cyclase(sGC) with EC 50 s of <0.5 nM, and 5 nM in CHO and GTM-3 E cells, respectively [1] [2].

Sulfamerazine sodium salt is a sulfonamide antibacterial.

AR-9281 (APAU) is a potent and selective inhibitor of soluble epoxide hydrolase (s-EH) potentially for the treatment of hypertension and type 2 diabetes

NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor (IC50: 30 nM and 200 nM for basal and NO-stimulated enzyme activity) commonly used in nitric oxide signaling pathway research. It inhibits sGC activity in mouse cerebellum homogenates and neuronal NO synthase (IC50: 17 nM and 20 nM), inhibits 3-morpholino-sydnonimine (SIN-1)-elicited cyclic GMP formation in human cultured umbilical vein endothelial cells (IC50: 30 nM), and completely inhibits NO-dependent relaxant responses in non-vascular smooth muscle (1 μM). NS-2028 also decreases vascular endothelial growth factor-induced angiogenesis and permeability.

Water Soluble Silk Fibroin is a type of silk fibroin known for its biocompatibility and biodegradability. It is applicable in 3D bioprinting.

Fat Soluble Vitamins Mix-3 In Ethanol（0.1%Bht） (Standard) is a reference standard of Fat Soluble Vitamins Mix-3 In Ethanol（0.1%Bht） intended for quantitative analysis, quality control, and related biochemical research applications.

Starch soluble is a biochemical reagent utilized as a biomaterial or organic compound in life science research.

Aniline blue (alcohol soluble) can be utilized as a biomaterial or organic compound relevant to life sciences research.

Prussian Blue Soluble serves as an excellent adsorbent and is employed as an antidote for poisoning by cesium or thallium ions. Additionally, it exhibits anticancer and antibacterial properties. Prussian Blue Soluble is also used as a contrast agent in photoacoustic and magnetic resonance imaging (MRI).

Mix-8 Fat-Solublevitamins In Methanol With 0.4%Bht+0.4%Vc (Standard) is a reference standard of Mix-8 Fat-Solublevitamins In Methanol With 0.4%Bht+0.4%Vc intended for quantitative analysis, quality control, and related biochemical research applications.