TN2257 |
Tanshinone IIB
|
17397-93-2
|
98%
|
|
Co-treatment with Tanshinone IIB (TSB) significantly inhibits the DNA laddering, cytotoxicity and apoptosis of rat cortical neurons induced by staurosporine in a...
|
T16042 |
Metaldehyde
|
108-62-3
|
98%
|
|
Metaldehyde is used for snails and other gastropods pesticide against.
|
TN3404 |
Altholactone
|
65408-91-5
|
98%
|
|
Altholactone may be a potential antimicrobial agent, particularly in ciprofloxacin-refractory S. aureus and E. faecalis infections. It can inhibit the growth of ...
|
T10434L2 |
AZD-5991 (S-enantiomer)
|
2143061-82-7
|
98%
|
|
AZD-5991 S-enantiomer is the less active enantiomer of AZD-5991. AZD-5991 S-enantiomer is an Mcl-1 inhibitor (IC50: 6.3 μM in FRET assay; Kd: 0.98 μM in SPR assa...
|
TN4604 |
Myricanone
|
32492-74-3
|
98%
|
|
Myricanone has antioxidant, and anticancer activities, it has apoptosis-promoting ability by triggering caspase activation, and suppression of cell proliferation...
|
TN4307 |
Isolimonexic acid
|
73904-93-5
|
98%
|
|
Isolimonexic acid exhibits cytotoxicity on MCF-7 cell lines, it also inhibits Panc-28 cancer cell growth.
|
T16694 |
Pyridoclax
|
1651890-44-6
|
98%
|
|
Pyridoclax is an inhibitor of potential Mcl-1.
|
TN1393 |
(-)-Anonaine
|
1862-41-5
|
98%
|
|
(-)-Anonaine has some anticancer activity, it induces apoptosis through Bax- and caspase-dependent pathways in human cervical cancer (HeLa) cells, it induces DNA...
|
TN3614 |
Cearoin
|
52811-37-7
|
98%
|
|
Cearoin has anti-inflammatory, and antiallergic activities, it can markedly inhibit inflammatory responses including LPS-induced NO production by suppressing the...
|
TN1093 |
Ginsenoside F4
|
181225-33-2
|
98%
|
|
Ginsenoside F4 has inhibitory effect on human lymphocytoma JK cell by inducing its apoptosis, the mechanism is related to the mitochondrial dysfunction and the i...
|
T14846 |
Bz 423
|
216691-95-1
|
98%
|
|
Bz 423 is a pro-apoptotic 1,4-benzodiazepine with selectivity for autoreactive lymphocytes and activates Bax and Bak.
|
TN2063 |
Physalin B
|
23133-56-4
|
98%
|
|
Physalin B shows antimalarial, anti-Trypanosoma cruzi, anti-bacterial, anti- leukemia activities, it has the potential to be developed as an effective chemothera...
|
TN2149 |
Reynosin
|
28254-53-7
|
98%
|
|
Reynosin has hepatoprotective, and anti-inflammatory effects, it has protective effect against dopamine-induced neuronal cell death, which may be due to the reci...
|
TN5263 |
1-[2,4-Dihydroxy-6-methoxy-3-(3-methyl-2-buten-1-yl)phenyl]-3-(4-hydroxyphenyl)-2-propen-1-one
|
569-83-5
|
98%
|
|
Xanthohumol, prenylchacone flavonoid, is a natural product with multi-biofunctions purified from Hops Humulus lupulus. Xanthohumol is effective against HIV-1 and...
|
TN3931 |
Ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid
|
57719-81-0
|
98%
|
|
Ent-11alpha-Hydroxy-15-oxokaur-16-en-19-oic acid has anti-cancer activity, it induces apoptosis of human malignant cancer cells, it also inhibits hepatocellular ...
|
TN5100 |
Taspine
|
602-07-3
|
98%
|
|
Taspine shows antitumor activity by modulating the EGFR signaling pathway of Erk1/2 and Akt in vitro and in vivo, it can inhibit growth and induce apoptosis of H...
|
T6650 |
Sabutoclax
|
1228108-65-3
|
98%
|
|
Sabutoclax(BI-97C1) is a pan-Bcl-2 inhibitor, including Bcl-xL, Bcl-2, Mcl-1 and Bfl-1 with IC50 of 0.31 μM, 0.32 μM, 0.20 μM and 0.62 μM, respectively.
|
TN3653 |
Cimidahurinine
|
142542-89-0
|
98%
|
|
Cimidahurinine can attenuate Doxorubicin (DOX)-induced cardiotoxicity in a dose-dependent manner with EC50 values of 45.79 uM; it protects against cardiotoxicity...
|
T10434 |
AZD-5991
|
2143061-81-6
|
98%
|
|
AZD-5991 is a potent and selective Mcl-1 inhibitor (IC50: 0.7 nM in FRET assay; Kd: 0.17 nM in SPR assay).
|
T14499 |
Bax activator-1
|
1638526-94-9
|
98%
|
|
Bax activator-1 (compound 106) is a Bax activator. It induces Bax-dependent tumor cell apoptosis[1].
|