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Search Result

Search Results for " myeloid "

236

Compounds

13

Natural Products

288

Recombinant Proteins

1

Libraries

Cat No. Product Name Synonyms Targets
T83738 SMAP 29 (ovine) TFA Sheep Myeloid Antimicrobial Peptide 29
SMAP 29, a bactericidal antimicrobial peptide and a cleavage product from the C-terminus of an ovine cathelicidin prepropeptide, is effective against P. aeruginosa strain PAO1 in both low- and high-salt conditions, as de...
T83706 BMAP 28 (bovine) TFA Cathelicidin-5 (132-158),Bovine Myeloid Antimicrobial Peptide 28
Bovine Myeloid Antimicrobial Peptide (BMAP) 28, a synthetic peptide derived from bovine cathelicidin-5 (amino acids 132-158), exhibits antimicrobial activity against E. coli, S. aureus, MRSA, S. epidermidis, and the fung...
T9919 Alemtuzumab Others
Alemtuzumab is a humanized monoclonal antibody against CD52 an antigen found on the surface of normal and malignant lymphocytes.
T9060 STM2457 Apoptosis , Others
STM2457 is an inhibitor of the RNA methyltransferase METTL3 (IC50=16.9 nM) with selective and oral activity.STM2457 can be used in acute myeloid leukemia (AML) studies.
T13950 UC-514321 Apoptosis , STAT
UC-514321 directly targets STAT3/5 and represses TET1 expression. UC-514321 has the potential to treat acute myeloid leukemia (AML) both in vitro and in vivo, with low toxicity.
T12253 Nrf2-IN-1 Others , Nrf2
Nrf2-IN-1 is an nuclear factor-erythroid 2-related factor 2 (Nrf2) inhibitor. Nrf2-IN-1 is developed for the research of acute myeloid leukemia (AML).
T7138 FB23-2 Apoptosis , Others
FB23-2 is a potent and selective mRNA N6-methyladenosine (m6A) demethylase FTO inhibitor(IC50 : 2.6 μM).
T12943 SNDX-5613 Epigenetic Reader Domain , Histone Methyltransferase
SNDX-5613 is a potent and specific inhibitor of Menin-MLL(Ki of 0.149 nM and a cell based IC50 of 10-20 nM). SNDX-5613 can be used for the research of MLL-rearranged (MLL-r) acute leukemias.
T9041 AES-350 Apoptosis , HDAC
AES-350 is a potent and orally active HDAC6 inhibitor(IC50 and a Ki of 0.0244 μM and 0.035 μM, respectively). It is also against HDAC-3, -8, and -11 in an enzymatic activity assay with IC50 values of 0.187 μM, 0.245 μM, ...
T13774 ML390 Others , Dehydrogenase
ML390 exerts its potent differentiation effect on multiple leukemia models.
T83698 Cathelicidin-2 (128-153) (chicken) TFA Fowlicidin-2 (128-153),CATH-2 (128-153),Myeloid Antimicrobial Peptide 27 (128-153)
Cathelicidin-2 (CATH-2) (128-153) is a synthetic antimicrobial peptide derived from amino acids 128-153 of chicken CATH-2, demonstrating activity against pathogens such as E. coli, S. aureus, S. enteritidis, and B. globi...
T8882 Vodobatinib K-0706 Bcr-Abl
Vodobatinib (K-0706) is a novel 3rd generation (3G) TKI effective against wild-type and mutated BCR-ABL1 with limited off-target activity.
T9014 SKI-178 Apoptosis , S1P Receptor
SKI-178 is a sphingosine kinase 1 (SphK1) inhibitor with IC50 of 0.1-1.8 μM. It induces prolonged mitosis followed by apoptotic cell death through the intrinsic apoptotic cascade. The sustained activation of CDK1 during ...
T64338 AKI603 AKI 603,AKI-603 Aurora Kinase
AKI603 is a novel small molecule inhibitor of Aurora kinase A (AurA)(IC50 = 12.3 nM). AKI603 is developed to overcome resistance mediated by BCR-ABL-T315I mutation. AKI603 exhibits strong anti-proliferative activity in l...
T24269 KPT-251 KPT251 Others
KPT-251 is a selective nuclear export inhibitor.
T8497 SX-682 CXCR
SX-682 is a potent, selective and orally bioavailable inhibitor of CXCR1/2 ,has the potential to treat castration-resistant prostate cancer.
T9765 TJ-M2010-5 MyD88
TJ-M2010-5 is a MyD88 inhibitor that binds to the TIR domain to interfere with its homodimerization and suppress MyD88 signaling. TJ-M2010-5 can be used in myocardial ischemia/reperfusion injury studies.
T11344 G150 DNA , cGAS
G150 inhibited interferon expression triggered by DSDNA with IC50 of 10.2 nM.G150 is an effective and highly selective inhibitor of human cyclic GMP-AMP synthase (H-CGAS).
T14919 CDKI-73 Apoptosis , CDK
CDKI-73 is a potent CDK9 inhibitor (Ki: 4 nM). It shows selective toxicity to CLL cells(LD50=80 nM) versus normal B cell and normal CD34+ cell(LD50>20 uM).The inhibition of CDK9 induces apoptosis and potentiates the effe...
T9705 TL-895 BTK
TL-895 is an ATP-competitive, and highly selective irreversible inhibitor of Bruton’s Tyrosine Kinase(BTK). TL-895 showed good potency with an IC50 of 1.5 nM and a Ki of 11.9 nM.
T16557 PNU-159682 Topoisomerase
PNU-159682 is a highly effective metabolite of the anthracycline nemorubicin. PNU-159682 has outstanding cytotoxicity. PNU-159682 is an effective ADCs cytotoxin.
T10606 BRD0705 GSK-3
BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor (IC50: 66 nM; Kd: 4.8 μM). BRD0705 displays increased selectivity for GSK3α (8-fold) versus GSK3β (IC50: 515 nM).
T38562 AKN-028 FLT
AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = 6 nM). AKN-028 causes dose-dependent inhibition of FLT3 autophosphorylation.
T2620 G-749 G749 Apoptosis , FLT , c-RET , TAM Receptor , Aurora Kinase
G-749, a new-type FLT3 inhibitor, exhibits effective and sustained inhibition of the FLT3 wild type and mutants.
T22553 Adaphostin 1-Adamantyl 4-((2,5-Dihydroxybenzyl)Amino)Benzoate,NSC 680410 Bcr-Abl
Adaphostin (NSC-680410) is a p210Bcr/Abl tyrosine kinase inhibitor with IC50 of 14 μM.
T10384 Farudodstat ASLAN003 Apoptosis , Dehydrogenase , DNA/RNA Synthesis
Farudodstat (ASLAN003) is an orally active and potent inhibitor of DHODH (Human Dihydroorotate Dehydrogenase) with antitumor activity. It has the potential to be a first-in-class candidate in AML.
T28475 Pyrazoloacridine PD-115934,NSC 366140,NSC-366140,PD 115,934,PD 115934 Apoptosis , Topoisomerase
Pyrazoloacridine (PD 115934) is a nucleic acid binding agent that inhibits the activity of topo I and II with an IC50 of 1.25 μM in K562 cells. Pyrazoloacridine shows anti-cancer activity.
T8978 DD1 3,3'-Diamino-4'-methoxyflavone,HUN85111 Proteasome
DD1 (HUN85111) is a proteasome inhibitor that induces human myeloid tumor-selective apoptosis.
T3184 Kevetrin hydrochloride Thioureidobutyronitrile HCl,thioureido butyronitrile hydrochloride,4-Isothioureidobutyronitrile hydrochloride Mdm2 , p53
Kevetrin hydrochloride (4-Isothioureidobutyronitrile hydrochloride) is a small molecule and activator of the tumor suppressor protein p53, with potential antineoplastic activity.
T1979 AVN-944 VX-944 Dehydrogenase
AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.
T16028 IMB-XH1 Mcl1-IN-2 BCL , Antibacterial
IMB-XH1 (Mcl1-IN-2) is a myeloid cell factor 1 (Mcl-1) inhibitor.
T2066 Quizartinib AC220 Apoptosis , FLT , Autophagy , Ligands for Target Protein for PROTAC
Quizartinib (AC220) is an inhibitor of FLT3 (Kd: 1.6 nM) and demonstrates high selectivity for FLT3 when tested against a panel of 227 additional kinases.
T0942 Quinacrine dihydrochloride Mepacrine dihydrochloride,SN-390,Quinacrine 2HCl Apoptosis , Mitophagy , DNA , Phospholipase , Parasite , Autophagy , Histamine Receptor
Quinacrine dihydrochloride (Mepacrine dihydrochloride) is the dihydrochloride salt of the 9-aminoacridine derivative quinacrine with potential antineoplastic and antiparasitic activities.
T2346L Enasidenib mesylate AG221 mesylate,AG 221 mesylate,AG-221 mesylate Dehydrogenase
Enasidenib mesylate (AG-221 mesylate) is a potent and selective IDH2 mutase inhibitor that promotes differentiation of leukemia myeloid cells for the treatment of acute myeloid leukemia.
T12629L MIK665 S-64315 BCL
MIK665 (S-64315) (S-64315) has an inhibitory effect on myeloid leukemia.
T25006 AGI-14100 AGI 14100 Dehydrogenase
AGI-14100 is a novel and orally available mIDH1 inhibitor.AGI-14100 is used for the treatment of primary human myeloid leukemia.
T12041 MIM1 Inhibitor of Mcl-1 BCL
MIM1 (Inhibitor of Mcl-1) is an myeloid cell factor 1 (Mcl-1) inhibitor.
T4231 MD2-IN-1 TLR
MD2-IN-1 is a Myeloid differentiation protein 2 (MD2) inhibitor with a KD of 189  μM for the recombinant human MD2 (rhMD2).
T6857 HLCL-61 hydrochloride HLCL61,HLCL-61 HCL Apoptosis , Histone Methyltransferase
HLCL-61 hydrochloride (HLCL-61 HCL) is a potent and selective PRMT5 inhibitor for the treatment of acute myeloid leukemia.
T9749 FHD-286 Epigenetic Reader Domain
FHD-286 is an inhibitor of BRM/BRG1 ATPase and can be used for studies on the treatment of BAF-related disorders such as acute myeloid leukemia.
T26828 BIT225 BIT 225,BIT-225
BIT-225 is a NCp7 zinc finger inhibitor. BIT225 inhibits HIV-1 replication in myeloid dendritic cells. BIT225 inhibits HIV-1 release from human macrophages. BIT225 inhibits bovine viral diarrhea virus in vitro and shows ...
T7672 MD2-TLR4-IN-1 TLR
MD2-TLR4-IN-1 is a myeloid differentiation protein 2/toll-like receptor 4 (MD2-TLR4) complex inhibitor.
T13519 6-Aminochrysene 6-Chrysenamine Others
6-Aminochrysene (6-Chrysenamine) is an inhibitor of the growth of several solid experimental tumors and can be used in studies about splenomegaly, breast cancer and myeloid leukemia.
T9843 FLT3-IN-16
FLT3-IN-16 exhibits potent inhibitory activity against FLT3 tyrosine kinase with an IC 50 of 1.1 μM. FLT3-IN-16 can be used for researching acute myeloid leukemia [1].
T40423 L48H37
L48H37 is a chemically stable analog of Curcumin. It exhibits potent inhibitory properties against myeloid differentiation protein 2 (MD2), acting as a specific inhibitor. Its mechanism involves inhibiting the interactio...
T7776 ADH-503 GB1275 Complement System
ADH-503 (GB1275) is a potent agonist of the integrin CD11b to mitigate myeloid cell immunosuppression.
T62750 TREM2 agonist-2 Others
TREM2 agonist-2 (I-192) is an orally active and potent myeloid triggered receptor 2 (TREM2) agonist for the study of neurodegenerative diseases.
T3099 Pinometostat EPZ-5676 Histone Methyltransferase
Pinometostat (EPZ-5676) has been used in trials studying the treatment of Leukemia, Acute Leukemias, Acute Myeloid Leukemia, Myelodysplastic Syndrome, and Acute Lymphocytic Leukemia, among others.
T6916 OICR-9429 OICR 9429 Histone Methyltransferase , JAK
OICR-9429 is a potent antagonist of the interaction that WDR5 effect with peptide regions of MLL and Histone 3. It reduces the viability of acute myeloid leukemia cells in vitro.
T14501 BAY-2402234 Dehydrogenase , DNA/RNA Synthesis
BAY-2402234 is an inhibitor of dihydroorotate dehydrogenase (DHODH) for the treatment of myeloid malignancies.BAY 2402234 is a selective low-nanomolar inhibitor of human DHODH enzymatic activity.

Compounds

SMAP 29 (ovine) TFA
T83738
Synonym: Sheep Myeloid Antimicrobial Peptide 29
Target:
BMAP 28 (bovine) TFA
T83706
Synonym: Cathelicidin-5 (132-158),Bovine Myeloid Antimicrobial Peptide 28
Target:
Alemtuzumab
T9919
Synonym:
Target: Others
STM2457
T9060
Synonym:
Target: Apoptosis, Others
UC-514321
T13950
Synonym:
Target: Apoptosis, STAT
Nrf2-IN-1
T12253
Synonym:
Target: Others, Nrf2
FB23-2
T7138
Synonym:
Target: Apoptosis, Others
SNDX-5613
T12943
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
AES-350
T9041
Synonym:
Target: Apoptosis, HDAC
ML390
T13774
Synonym:
Target: Others, Dehydrogenase
Cathelicidin-2 (128-153) (chicken) TFA
T83698
Synonym: Fowlicidin-2 (128-153),CATH-2 (128-153),Myeloid Antimicrobial Peptide 27 (128-153)
Target:
Vodobatinib
T8882
Synonym: K-0706
Target: Bcr-Abl
SKI-178
T9014
Synonym:
Target: Apoptosis, S1P Receptor
AKI603
T64338
Synonym: AKI 603,AKI-603
Target: Aurora Kinase
KPT-251
T24269
Synonym: KPT251
Target: Others
SX-682
T8497
Synonym:
Target: CXCR
TJ-M2010-5
T9765
Synonym:
Target: MyD88
G150
T11344
Synonym:
Target: DNA, cGAS
CDKI-73
T14919
Synonym:
Target: Apoptosis, CDK
TL-895
T9705
Synonym:
Target: BTK
PNU-159682
T16557
Synonym:
Target: Topoisomerase
BRD0705
T10606
Synonym:
Target: GSK-3
AKN-028
T38562
Synonym:
Target: FLT
G-749
T2620
Synonym: G749
Target: Apoptosis, FLT, c-RET, TAM Receptor, Aurora Kinase
Adaphostin
T22553
Synonym: 1-Adamantyl 4-((2,5-Dihydroxybenzyl)Amino)Benzoate,NSC 680410
Target: Bcr-Abl
Farudodstat
T10384
Synonym: ASLAN003
Target: Apoptosis, Dehydrogenase, DNA/RNA Synthesis
Pyrazoloacridine
T28475
Synonym: PD-115934,NSC 366140,NSC-366140,PD 115,934,PD 115934
Target: Apoptosis, Topoisomerase
DD1
T8978
Synonym: 3,3'-Diamino-4'-methoxyflavone,HUN85111
Target: Proteasome
Kevetrin hydrochloride
T3184
Synonym: Thioureidobutyronitrile HCl,thioureido butyronitrile hydrochloride,4-Isothioureidobutyronitrile hydrochloride
Target: Mdm2, p53
AVN-944
T1979
Synonym: VX-944
Target: Dehydrogenase
IMB-XH1
T16028
Synonym: Mcl1-IN-2
Target: BCL, Antibacterial
Quizartinib
T2066
Synonym: AC220
Target: Apoptosis, FLT, Autophagy, Ligands for Target Protein for PROTAC
Quinacrine dihydrochloride
T0942
Synonym: Mepacrine dihydrochloride,SN-390,Quinacrine 2HCl
Target: Apoptosis, Mitophagy, DNA, Phospholipase, Parasite, Autophagy, Histamine Receptor
Enasidenib mesylate
T2346L
Synonym: AG221 mesylate,AG 221 mesylate,AG-221 mesylate
Target: Dehydrogenase
MIK665
T12629L
Synonym: S-64315
Target: BCL
AGI-14100
T25006
Synonym: AGI 14100
Target: Dehydrogenase
MIM1
T12041
Synonym: Inhibitor of Mcl-1
Target: BCL
MD2-IN-1
T4231
Synonym:
Target: TLR
HLCL-61 hydrochloride
T6857
Synonym: HLCL61,HLCL-61 HCL
Target: Apoptosis, Histone Methyltransferase
FHD-286
T9749
Synonym:
Target: Epigenetic Reader Domain
BIT225
T26828
Synonym: BIT 225,BIT-225
Target:
MD2-TLR4-IN-1
T7672
Synonym:
Target: TLR
6-Aminochrysene
T13519
Synonym: 6-Chrysenamine
Target: Others
FLT3-IN-16
T9843
Synonym:
Target:
L48H37
T40423
Synonym:
Target:
ADH-503
T7776
Synonym: GB1275
Target: Complement System
TREM2 agonist-2
T62750
Synonym:
Target: Others
Pinometostat
T3099
Synonym: EPZ-5676
Target: Histone Methyltransferase
OICR-9429
T6916
Synonym: OICR 9429
Target: Histone Methyltransferase, JAK
BAY-2402234
T14501
Synonym:
Target: Dehydrogenase, DNA/RNA Synthesis
1 2 3 4 5
Cat No. Product Name Synonyms Targets
T6S1435 Notopterol Apoptosis , Others
1. Notopterol induces apoptosis and inhibits cell cycle-specific.
T1882 Meisoindigo N-Methylisoindigotin,Methylisoindigotin,Natura-α,Dian III Apoptosis
Meisoindigo (Natura-α) is a derivative of indigo natural, might induces apoptosis and myeloid differentiation of acute myeloid leukemia (AML).
TN1369 Alloimperatorin Prangenidin Others
Alloimperatorin (Prangenidin) exhibits in vitro antitumor activity in HL-60 acute myeloid leukemia cancer cells via inducing apoptosis, cell cycle disruption and inhibition of cell migration. It photosensitizes efficient...
T34398 Rotundifuran Others
Rotundifuran is extracted from the fruit of Vitex rotundifolia. Rotundifuran inhibits cell cycle progression and induces apoptosis in human myeloid leukemia cells.
T4036 Solasodine Solancarpidine,Purapuridine,Solasodin Apoptosis , Others , E1/E2/E3 Enzyme , Antifungal
Solasodine (Purapuridine)(Purapuridine) is a poisonous alkaloid chemical compound that occurs in plants of the Solanaceae family. Solasodine showed selective cytotoxicity against cervical cancer cell line (HeLa) and huma...
T11060 DMAPT Dimethylamino Parthenolide NF-κB
DMAPT (Dimethylamino Parthenolide) is a water-soluble analogue of Parthenolide (PTL). It is an orally active NF-κB inhibitor with an LD50 of 1.7 μM on primary acute myeloid leukemia cells.
TN1215 (2S)-2'-Methoxykurarinone 2'-Methoxykurarinone,2'-O-Methylkurarinone Akt , Antifection
(2S)-2'-Methoxykurarinone is isolated from the roots of Sophora flavescens. (2S)-2'-Methoxykurarinone has anti-inflammatory, antipyretic, antidiabetic, and antineoplastic effects. (2S)-2'-Methoxykurarinone inhibits osteo...
T4S1943 Kirenol Kirel Wnt/beta-catenin
1. Kirenol (Kirel) has anti-oxidant, anti-inflammatory, anti-allergic, and anti-arthritic activities. 2. Kirenol is effective against gram-positive bacteria. 3. Kirenol possesses antitumor action on human chronic myeloid...
TN2211 Silybin B Silibinin B Apoptosis , Beta Amyloid , Bcr-Abl
Silybin B (Silibinin B) is an effective inhibitor of raloxifene 4 '- and 6-glucosalylation, an effective anti-fibrinogenic and anti-oligomeric component of Silymarin, with free radical scavenging activity of 1, 1-dipheny...
TN5585 14-Deoxy-11-hydroxyandrographolide
14-Deoxy-11-hydroxyandrographolide shows potent cell differentiation-inducing activity towards mouse myeloid leukemia (M1) cells.
T80259 PMAP-23
PMAP-23 is an antimicrobial peptide (AMP) with biological activity, derived from porcine myeloid cells.
TN5593 Euphohelioscopin A
Euphohelioscopin A, an activator of protein kinase C (PKC), it inhibits proliferation and induces differentiation of the myeloid leukemia cell lines THP-1 and HL-60. Euphohelioscopin A has anti-inflammary activity, it ex...
T36417 Nargenicin Antibiotic 47444
Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S. aureus, methicilin resistant S. aureus (MRSA), and M. luteus (MICs = 0.6, 0.3, and 2.5 μg/ml, respectively) over a panel of 11 Gram-positive...

Natural Products

Notopterol
T6S1435
Synonym:
Target: Apoptosis, Others
Meisoindigo
T1882
Synonym: N-Methylisoindigotin,Methylisoindigotin,Natura-α,Dian III
Target: Apoptosis
Alloimperatorin
TN1369
Synonym: Prangenidin
Target: Others
Rotundifuran
T34398
Synonym:
Target: Others
Solasodine
T4036
Synonym: Solancarpidine,Purapuridine,Solasodin
Target: Apoptosis, Others, E1/E2/E3 Enzyme, Antifungal
DMAPT
T11060
Synonym: Dimethylamino Parthenolide
Target: NF-κB
(2S)-2'-Methoxykurarinone
TN1215
Synonym: 2'-Methoxykurarinone,2'-O-Methylkurarinone
Target: Akt, Antifection
Kirenol
T4S1943
Synonym: Kirel
Target: Wnt/beta-catenin
Silybin B
TN2211
Synonym: Silibinin B
Target: Apoptosis, Beta Amyloid, Bcr-Abl
14-Deoxy-11-hydroxyandrographolide
TN5585
Synonym:
Target:
PMAP-23
T80259
Synonym:
Target:
Euphohelioscopin A
TN5593
Synonym:
Target:
Nargenicin
T36417
Synonym: Antibiotic 47444
Target:

Recombinant Proteins

Species：
Human (150)
Mouse (71)
Rat (22)
Cynomolgus (17)
Canine (8)
Rhesus (5)
Cynomolgus,Rhesus (4)
HIV-2 (2)
Human (2)
Bovine (1)
Expression System：
HEK293 (196)
Human Cells (37)
E. coli (35)
Baculovirus-Insect Cells (12)
Yeast (5)
Baculovirus (1)
CHO (1)
E.coli (1)
Tag：
His (96)
hFc (42)
C-His-Avi (20)
C-6His (17)
C-His (15)
Tag Free (14)
C-Fc (8)
N-terminal 6xHis-SUMO-tagged (6)
N-terminal 10xHis-tagged and C-terminal Myc-tagged (5)
None (5)
Cat No. Product Name Species Expression System
TMPY-01148 TREM-2 Protein, Human, Recombinant (His) Human HEK293
Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b...
TMPY-00432 TREM-2 Protein, Mouse, Recombinant (hFc) Mouse HEK293
Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b...
TMPY-01774 TREM-1 Protein, Human, Recombinant (His) Human HEK293
TREM1 (triggering receptor expressed on myeloid cells) is a type I transmembrane protein with a single Ig-like domain, and is selectively expressed on blood neutrophils and a subset of monocytes. As a member of the growi...
TMPY-01703 TREM-2 Protein, Mouse, Recombinant (His) Mouse HEK293
Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b...
TMPY-01648 TREML2 Protein, Human, Recombinant (His) Human HEK293
Trem-like transcript 2 protein, also known as Triggering receptor expressed on myeloid cells-like protein 2, TREML2 and TLT2, is a single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like...
TMPY-06527 TREM-1 Protein, Mouse, Recombinant (His) Mouse HEK293
TREM1 (triggering receptor expressed on myeloid cells) is a type I transmembrane protein with a single Ig-like domain, and is selectively expressed on blood neutrophils and a subset of monocytes. As a member of the growi...
TMPY-00943 TREM-1 Protein, Human, Recombinant (His & hFc) Human HEK293
TREM1 (triggering receptor expressed on myeloid cells) is a type I transmembrane protein with a single Ig-like domain, and is selectively expressed on blood neutrophils and a subset of monocytes. As a member of the growi...
TMPY-04264 SF20 Protein, Human, Recombinant (mFc) Human HEK293
TMPY-00034 SF20 Protein, Human, Recombinant (His) Human HEK293
TMPY-06598 TREM-2 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b...
TMPY-06566 TREM-2 Protein, Human, Recombinant (hFc) Human HEK293
Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b...
TMPH-00230 Cathelicidin-6 Protein, Bovine, Recombinant (His & SUMO) Bovine E. coli
Exerts a potent antimicrobial activity against Gram-negative and Gram-positive bacteria, including methicillin-resistant Staphylococcus aureus, and fungi.
TMPJ-00115 TREM-2 Protein, Human, Recombinant (Avi & His), Biotinylated Human Human Cells
TREM2 is a cell surface receptor of the immunoglobulin superfamily. TREM2 is a type-1 transmembrane protein that shuttles to the plasma membrane where it exerts its cell autonomous biological functions. TREM2 undergoes r...
TMPJ-00117 TREM-2 Protein, Human, Recombinant (mFc) Human Human Cells
TREM2 is a cell surface receptor of the immunoglobulin superfamily. TREM2 is a type-1 transmembrane protein that shuttles to the plasma membrane where it exerts its cell autonomous biological functions. TREM2 undergoes r...
TMPJ-00537 Siglec-3/CD33 Protein, Human, Recombinant (hFc & His) Human Human Cells
CD33 is a type I Lectin belonging to the Ig superfamily. CD33 contains an N terminal Ig like V type domain, which mediates sialic acid binding, followed by one Ig like C2 type domain, a transmembrane region and a cytopla...
TMPJ-00589 TREML2 Protein, Human, Recombinant (hFc) Human Human Cells
Trem-like transcript 2 protein (TLT2), also known as Triggering receptor expressed on myeloid cells-like protein 2, TLT2 and C6orf76, is single-pass type I membrane protein. TREML2 contains one Ig-like V-type domain, whi...
TMPH-01106 CD300LB Protein, Human, Recombinant (His) Human E. coli
CD300LB Protein, Human, Recombinant (His) is expressed in E. coli.
TMPJ-01144 TREML2 Protein, Mouse, Recombinant (His) Mouse Human Cells
Trem-like transcript 2 protein (TLT2), also known as Triggering receptor expressed on myeloid cells-like protein 2, TLT2 and C6orf76, is single-pass type I membrane protein. TREML2 contains one Ig-like V-type domain, whi...
TMPJ-00193 TREML1 Protein, Human, Recombinant (hFc) Human Human Cells
Triggering Receptor Expressed on Myeloid Cells-Like Protein 1 (TREML1) is a single-pass type I membrane protein. TREML1 precursor contains a 15 amino acid signal peptide, a 147 amino acid extracellular domain with an Ig-...
TMPY-01840 TLT-1/TREML1 Protein, Human, Recombinant (His) Human HEK293
Trem-like transcript 1 protein, also known as Triggering receptor expressed on myeloid cells-like protein 1, TREML1 and TLT-1, is a cytoplasm and single-pass type I membrane protein. TREML1 / TLT-1 is expressed exclusive...
TMPJ-01193 CLM-9 Protein, Human, Recombinant (aa 19-247, His) Human Human Cells
CMRF35-Like Molecule 9 (CD300LG) is a single-pass type I membrane protein which belongs to the CD300 family. CD300LG has one Ig-like V-type domain which mediates binding to lymphocyte. CD300LG is highly expressed in hear...
TMPJ-00700 GADD45B Protein, Human, Recombinant (His) Human E. coli
Growth Arrest and DNA Damage-Inducible Protein GADD45 β (GADD45B) is a member of the GADD45 family. GADD45B has been shown to interact with MAP3K4, ASK1, MAP2K7, and GADD45GIP1. GADD45B is involved in the regulation of g...
TMPJ-00014 Resistin Protein, Human, Recombinant (His) Human E. coli
Resistin known as adipose tissue-specific secretory factor (ADSF) or C/EBP-epsilon-regulated myeloid-specific secreted cysteine-rich protein (XCP1) that seems to suppress insulin ability to stimulate glucose uptake into ...
TMPJ-01470 SCF Protein, Human, Recombinant Human E.coli
Stem Cell Factor (SCF) is a hematopoietic growth factor that exerts its activity at the early stages of hematopoiesis. SCF stimulates the proliferation of myeloid, erythroid, and lymphoid progenitors in bone marrow cultu...
TMPY-01302 CD200R Protein, Human, Recombinant (His) Human HEK293
The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules associating with the immu...
TMPY-02268 CD93/C1qR1 Protein, Human, Recombinant (His) Human HEK293
CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protei...
TMPY-06844 CD93/C1qR1 Protein, Mouse, Recombinant (hFc) Mouse HEK293
CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protei...
TMPY-06027 CD93/C1qR1 Protein, Mouse, Recombinant (His) Mouse HEK293
CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protei...
TMPY-02092 CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His) Human HEK293
CLEC12A is a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signaling, glycop...
TMPY-02409 Siglec-3/CD33 Protein, Cynomolgus, Rhesus, Recombinant (His) Cynomolgus,Rhesus HEK293
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-03805 Siglec-3/CD33 Protein, Human, Recombinant (His) Human HEK293
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-04952 Siglec-3/CD33 Protein, Human, Recombinant (His), Biotinylated Human HEK293
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-02304 Siglec-3/CD33 Protein, Mouse, Recombinant (His) Mouse HEK293
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPJ-00042 TSLP Protein, Human, Recombinant Human E. coli
Thymic stromal lymphopoietin (TSLP) is a novel member of the hemopoietic cytokine family that promotes the development of B cells and shares overlapping activity with IL-7. The human TSLP protein comprises a 28 amino aci...
TMPY-04805 Siglec-3/CD33 Protein, Human, Recombinant Human HEK293
Myeloid cell surface antigen CD33 also known as Sialic acid binding Ig-like lectin 3, CD33 antigen or Siglec-3, is a member of the immunoglobulin superfamily and SIGLEC (sialic acid binding Ig-like lectin) family. This S...
TMPY-05446 CD200 Protein, Human, Recombinant (hFc) Human HEK293
CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-02971 CLEC10A Protein, Human, Recombinant (hFc) Human HEK293
CLEC10A, also known as the macrophage galactose-type calcium-type lectins (MGLs; CD301) constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. MGLs/CD301 is ...
TMPY-02170 SCF Protein, Human, Recombinant (aa 1-189, His) Human Baculovirus-Insect Cells
Similar to Kit ligand precursor (C-kit ligand), also known as Stem cell factor (SCF), Mast cell growth factor (MGF), or Hematopoietic growth factor KL. SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encod...
TMPY-05423 C-MPL Protein, Rat, Recombinant (hFc) Rat HEK293
CD11, also known as c-MPL, is a 635 amino acid transmembrane domain, with two extracellular cytokine receptor domains and two intracellular cytokine receptor box motifs. It is expressed at a low level in a large number o...
TMPY-02105 SCF Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Similar to Kit ligand precursor (C-kit ligand), also known as Stem cell factor (SCF), Mast cell growth factor (MGF), or Hematopoietic growth factor KL. SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encod...
TMPY-03945 Latent TGF beta 1 Protein, Rat, Recombinant (His) Rat HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-04211 Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-00608 TGF beta 1 Protein, Rat/Mouse, Recombinant Mouse,Rat HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-00586 CLEC-2 Protein, Mouse, Recombinant (hFc) Mouse HEK293
CLEC1B, also known as CLEC2, is a C-type lectin-like receptor expressed in myeloid cells and NK cells. Natural killer (NK) cells express multiple calcium-dependent (C-type) lectin-like receptors, such as CD94 and NKG2D, ...
TMPY-02638 TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant Human,Rhesus,Cynomolgus,Canine CHO
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-01133 Latent TGF beta 1 Protein, Human, Recombinant (His) Human HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-00500 Latent TGF beta 1 Protein, Mouse, Recombinant (His) Mouse HEK293
TGF-beta 1 is a member of the transforming growth factor beta (TGF-beta) family. The transforming growth factor-beta family of polypeptides are involved in the regulation of cellular processes, including cell division, d...
TMPY-02709 P-Selectin Protein, Human, Recombinant (His) Human HEK293
P selectin (SELP) is a 140kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. SELP mediates rapid rolling of leukocyte rolling over vascular surfaces during the in...
TMPY-05274 IL-23R Protein, Human, Recombinant (His) Human HEK293
IL23R, also known as the IL23 receptor, belongs to the type I cytokine receptor family, Type 2 subfamily. It contains 2 fibronectin type-III domains and is expressed by monocytes, Th1, Th0, NK, and dendritic cells. Isofo...
TMPY-05039 LTBR Protein, Human, Recombinant (hFc) Human HEK293
LTBR (lymphotoxin beta receptor (TNFR superfamily, member 3)) is a member of the tumor necrosis factor (TNF) family of receptors. The tumor necrosis factor receptor is a trimeric cytokine receptor that binds tumor necros...
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TREM-2 Protein, Human, Recombinant (His)
TMPY-01148
Species: Human
Expression System: HEK293
TREM-2 Protein, Mouse, Recombinant (hFc)
TMPY-00432
Species: Mouse
Expression System: HEK293
TREM-1 Protein, Human, Recombinant (His)
TMPY-01774
Species: Human
Expression System: HEK293
TREM-2 Protein, Mouse, Recombinant (His)
TMPY-01703
Species: Mouse
Expression System: HEK293
TREML2 Protein, Human, Recombinant (His)
TMPY-01648
Species: Human
Expression System: HEK293
TREM-1 Protein, Mouse, Recombinant (His)
TMPY-06527
Species: Mouse
Expression System: HEK293
TREM-1 Protein, Human, Recombinant (His & hFc)
TMPY-00943
Species: Human
Expression System: HEK293
SF20 Protein, Human, Recombinant (mFc)
TMPY-04264
Species: Human
Expression System: HEK293
SF20 Protein, Human, Recombinant (His)
TMPY-00034
Species: Human
Expression System: HEK293
TREM-2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06598
Species: Human
Expression System: HEK293
TREM-2 Protein, Human, Recombinant (hFc)
TMPY-06566
Species: Human
Expression System: HEK293
Cathelicidin-6 Protein, Bovine, Recombinant (His & SUMO)
TMPH-00230
Species: Bovine
Expression System: E. coli
TREM-2 Protein, Human, Recombinant (Avi & His), Biotinylated
TMPJ-00115
Species: Human
Expression System: Human Cells
TREM-2 Protein, Human, Recombinant (mFc)
TMPJ-00117
Species: Human
Expression System: Human Cells
Siglec-3/CD33 Protein, Human, Recombinant (hFc & His)
TMPJ-00537
Species: Human
Expression System: Human Cells
TREML2 Protein, Human, Recombinant (hFc)
TMPJ-00589
Species: Human
Expression System: Human Cells
CD300LB Protein, Human, Recombinant (His)
TMPH-01106
Species: Human
Expression System: E. coli
TREML2 Protein, Mouse, Recombinant (His)
TMPJ-01144
Species: Mouse
Expression System: Human Cells
TREML1 Protein, Human, Recombinant (hFc)
TMPJ-00193
Species: Human
Expression System: Human Cells
TLT-1/TREML1 Protein, Human, Recombinant (His)
TMPY-01840
Species: Human
Expression System: HEK293
CLM-9 Protein, Human, Recombinant (aa 19-247, His)
TMPJ-01193
Species: Human
Expression System: Human Cells
GADD45B Protein, Human, Recombinant (His)
TMPJ-00700
Species: Human
Expression System: E. coli
Resistin Protein, Human, Recombinant (His)
TMPJ-00014
Species: Human
Expression System: E. coli
SCF Protein, Human, Recombinant
TMPJ-01470
Species: Human
Expression System: E.coli
CD200R Protein, Human, Recombinant (His)
TMPY-01302
Species: Human
Expression System: HEK293
CD93/C1qR1 Protein, Human, Recombinant (His)
TMPY-02268
Species: Human
Expression System: HEK293
CD93/C1qR1 Protein, Mouse, Recombinant (hFc)
TMPY-06844
Species: Mouse
Expression System: HEK293
CD93/C1qR1 Protein, Mouse, Recombinant (His)
TMPY-06027
Species: Mouse
Expression System: HEK293
CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His)
TMPY-02092
Species: Human
Expression System: HEK293
Siglec-3/CD33 Protein, Cynomolgus, Rhesus, Recombinant (His)
TMPY-02409
Species: Cynomolgus,Rhesus
Expression System: HEK293
Siglec-3/CD33 Protein, Human, Recombinant (His)
TMPY-03805
Species: Human
Expression System: HEK293
Siglec-3/CD33 Protein, Human, Recombinant (His), Biotinylated
TMPY-04952
Species: Human
Expression System: HEK293
Siglec-3/CD33 Protein, Mouse, Recombinant (His)
TMPY-02304
Species: Mouse
Expression System: HEK293
TSLP Protein, Human, Recombinant
TMPJ-00042
Species: Human
Expression System: E. coli
Siglec-3/CD33 Protein, Human, Recombinant
TMPY-04805
Species: Human
Expression System: HEK293
CD200 Protein, Human, Recombinant (hFc)
TMPY-05446
Species: Human
Expression System: HEK293
CLEC10A Protein, Human, Recombinant (hFc)
TMPY-02971
Species: Human
Expression System: HEK293
SCF Protein, Human, Recombinant (aa 1-189, His)
TMPY-02170
Species: Human
Expression System: Baculovirus-Insect Cells
C-MPL Protein, Rat, Recombinant (hFc)
TMPY-05423
Species: Rat
Expression System: HEK293
SCF Protein, Mouse, Recombinant (His)
TMPY-02105
Species: Mouse
Expression System: Baculovirus-Insect Cells
Latent TGF beta 1 Protein, Rat, Recombinant (His)
TMPY-03945
Species: Rat
Expression System: HEK293
Latent TGF beta 1 Protein, Cynomolgus, Recombinant (His)
TMPY-04211
Species: Cynomolgus
Expression System: HEK293
TGF beta 1 Protein, Rat/Mouse, Recombinant
TMPY-00608
Species: Mouse,Rat
Expression System: HEK293
CLEC-2 Protein, Mouse, Recombinant (hFc)
TMPY-00586
Species: Mouse
Expression System: HEK293
TGF beta 1 Protein, Human/Rhesus/Cynomolgus/Canine, Recombinant
TMPY-02638
Species: Human,Rhesus,Cynomolgus,Canine
Expression System: CHO
Latent TGF beta 1 Protein, Human, Recombinant (His)
TMPY-01133
Species: Human
Expression System: HEK293
Latent TGF beta 1 Protein, Mouse, Recombinant (His)
TMPY-00500
Species: Mouse
Expression System: HEK293
P-Selectin Protein, Human, Recombinant (His)
TMPY-02709
Species: Human
Expression System: HEK293
IL-23R Protein, Human, Recombinant (His)
TMPY-05274
Species: Human
Expression System: HEK293
LTBR Protein, Human, Recombinant (hFc)
TMPY-05039
Species: Human
Expression System: HEK293
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Cat No. Product Name
L2140 Cancer Cell Differentiation Compound Library

413 compounds
A unique collection of 413 cancer cell differentiation inducing compounds for high throughput and high content screening;

Libraries

Cancer Cell Differentiation Compound Library
L2140
Compounds: 413
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