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Search Result

Search Results for " epigenetic "

Targets

Epigenetic Reader Domain

147

Compounds

6

Natural Products

33

Recombinant Proteins

5

Libraries

Cat No. Product Name Synonyms Targets
T72013 Epigenetic Multiple Ligand
Epigenetic Multiple Ligand is a cell-permeable inhibitor of substrate processing by several chromatin-associated enzymes, including SIRT1/2, H3/SET7, H3/p300/CBP, H4/RmtA, PABP1/CARM1, and H4/PRMT1. It acts by inducing e...
T82458 Epigenetic factor-IN-1 Sirtuin
Epigenetic factor-IN-1 (40569Z) is an epigenetic factor inhibitor that exhibits potent binding affinity for SIRT7. It is utilized in the study of liver cancer [1].
T15424 GSK1379725A Epigenetic Reader Domain
GSK1379725A is a selective BPTF ligand (Kd: 2.8 uM). It also shows no binding activity for Brd4.
T2072 BET bromodomain inhibitor Epigenetic Reader Domain
BET bromodomain inhibitor is a potent BET inhibitor.
T11925 M‑89 Epigenetic Reader Domain , Histone Methyltransferase
M-89, a highly potent and specific inhibitor of the menin-mixed lineage leukemia (Menin-MLL) protein-protein interaction, exhibits a Kd of 1.4 nM for menin binding. This compound holds potential for treating MLL leukemia...
T5440 Dbet57 Epigenetic Reader Domain
dBET57 is heterobifunctional degrader of BRD4 based on the PROTAC technology, exhibits significant degradation of BRD4BD1 with a DC50/5h of 500 nM ,and inactive on BRD4BD2
T4495 DBET1 Epigenetic Reader Domain
dBET1 is a hybrid molecule that combines (+)-JQ1 and thalidomide. It induces cereblon-dependent BET protein degradation in vitro (EC50: 430 nM) and induces apoptosis.
T6668 SGC-CBP30 Epigenetic Reader Domain , Histone Acetyltransferase
SGC-CBP30 is an effective CREBBP/EP300 inhibitor (IC50: 21/38 nM).
T5130 DBET6 Apoptosis , Epigenetic Reader Domain
dBET6 is a selective and cell-permeable degrader of BET based on PROTAC (IC50: 14 nM). It has antitumor activity.
T1854 MS436 Epigenetic Reader Domain
MS436 is a selective, small-molecule inhibitor for the BRD4 bromodomains.
T3311 GSK6853 Epigenetic Reader Domain
GSK6853 is a potent, soluble, cell-active, and highly selective inhibitor of the BRPF1 bromodomain.
TQ0058 MI-463 Epigenetic Reader Domain , Histone Methyltransferase
MI-463 is a potent and orally bioavailable inhibitor of the menin-mLL interaction (IC50: 15.3 nM).
T16072 MI-538 Epigenetic Reader Domain , Histone Methyltransferase
MI-538 is an interaction between menin and MLL fusion proteins inhibitor(IC50 of 21 nM).
T5362 Y06036 Epigenetic Reader Domain
Y06036, a potent and selective BET inhibitor, can bind to the BRD4(1) bromodomain (Kd: 82 nM).
T19935 XD14 Epigenetic Reader Domain
XD14 is an inhibitor of BET bromodomain (Kd of 160 nM, 170 nM, 380 nM, 490 nM, 830 nM and 850 nM for BRD4(1), BRD2(1), BRD3(1), BRD3(2), BRD2(2) and BRD4(2), respectively).
T3973 PF-CBP1 Epigenetic Reader Domain
PF-CBP1 HCl is a highly selective inhibitor of the bromodomain of CREB-binding protein(CREBBP). It inhibits CREBBP (IC50: 125 nM) and p300 bromodomains (IC50: 363 nM).
T14685 BMS-986158 Epigenetic Reader Domain
BMS-986158 is a highly effective BET inhibitor, demonstrating IC50 values of 6.6 nM in NCI-H211 small cell lung cancer (SCLC) cells and 5 nM in MDA-MB231 triple negative breast cancer (TNBC) cells.
T13363 Y06137 Epigenetic Reader Domain , PKC
Y06137 is an effective and selective BET inhibitor with a Kd of 81 nM for BRD4(1) bromodomain. Y06137 can be used for research on the treatment of castration-resistant prostate cancer.
T6783 BI-7273 Epigenetic Reader Domain
BI-7273 is an effective, specific, BRD9 BD Inhibitor, which can infiltrate cell.
TQ0083 NI-57 Epigenetic Reader Domain
NI-57 is an inhibitor of proteins of bromodomain and plant homeodomain finger-containing (BRPF) family, with IC50s of 3.1, 46 and 140 nM for BRPF1, BRPF2 (BRD1) and BRPF3, respectively.
TQ0253 PLX51107 Epigenetic Reader Domain
PLX51107 is a potent and selective BET inhibitor (Kds: 1.6, 2.1, 1.7, and 5 nM for BRD2-BD1, BRD3-BD1, BRD4-BD1, and BRDT-BD1).
T12112 MS402 Epigenetic Reader Domain
MS402 is a novel BD1-selective BET BrD inhibitor.
TQ0069 MI-503 Epigenetic Reader Domain , Histone Methyltransferase
MI-503 is a highly effective and orally bioavailable inhibitor of the menin-mLL interaction.
T16321 NI-42 Epigenetic Reader Domain
NI-42 is a structurally orthogonal chemical probe for the BRPFs and is biased. It effective inhibitor of the BRD of the BRPFs (IC50s of BRPF1/2/3=7.9/48/260 nM; Kds of BRPF1/2/3=40/210/940 nM). It also has excellent sele...
T9749 FHD-286 Epigenetic Reader Domain
FHD-286 is an inhibitor of BRM/BRG1 ATPase and can be used for studies on the treatment of BAF-related disorders such as acute myeloid leukemia.
T2127 OF-1 Epigenetic Reader Domain
OF-1 is a potent inhibitor of BRPF1B and BRPF2 bromodomain.
T17697 BRD7-IN-1 Epigenetic Reader Domain
BRD7-IN-1, a modified derivative of BI7273 (BRD7/9 inhibitor), forms PROTAC VZ185 through linkage to a VHL ligand, demonstrating potent activity against BRD7/9 with DC50 values of 4.5 and 1.8 nM, respectively [1].
T11136 E-7386 E7386 Epigenetic Reader Domain
E-7386 is an oral active CBP/ -catenin modulator.
T17311 (+)-JQ1 PA Epigenetic Reader Domain
(+)-JQ1 PA is a derivative of the Bromodomain and extra-terminal (BET) inhibitor JQ1(IC50 of 10.4 nM).
T9568 SGC-SMARCA-BRDVIII Epigenetic Reader Domain
SGC-SMARCA-BRDVIII is a potent and selective inhibitor of SMARCA2, SMARCA4, PB1(2), PB1(3) and PB1(5) with Kds of 35 nM, 36 nM, 3.7 μM, 2.0 μM and 13 nM, respectively.
T5417 INCB-057643 Apoptosis , Epigenetic Reader Domain
INCB057643 is a potent, selective and orally bioavailable BET inhibitor.
T5434 ARV-825 Epigenetic Reader Domain
ARV-825, a heterobifunctional PROTAC (Proteolysis Targeting Chimera) that recruits BRD4 to the E3 ubiquitin ligase cereblon leading to fast, efficient, and prolonged degradation of BRD4 in all BL cell lines tested.
T5442 A1874 Epigenetic Reader Domain , PROTACs
A1874 is a nutlin-based and BRD4-degrading PROTAC which induces BRD4 degradation in cells. Effective in inhibiting many cancer cell lines proliferation.
T5435 ARV-771 Epigenetic Reader Domain
ARV-771 is a potent BET degrader based on PROTAC technology with Kds of 34, 4.7, 8.3, 7.6, 9.6, and 7.6 nM for BRD2(1), BRD2(2), BRD3(1), BRD3(2), BRD4(1), and BRD4(2), respectively[1].
T6939 PFI-3 PFI 3 Epigenetic Reader Domain
PFI-3 is a selective chemical inhibitor for SMARCA (2/4) (Kd = 89 nM)and PBI (5) bromodomains which may result in the delay and prevention of breast cancer.
T3624 A-366 A 366,A366 Epigenetic Reader Domain , Histone Methyltransferase
A-366 is a highly selective peptide-competitive histone methyltransferase G9a inhibitor with IC50s of 3.3 and 38 nM for G9a and GLP, respectively.It is more than 1,000-fold selective for G9a and GLP over the other 21 met...
T6786 BI-9564 BI 9564,BI9564 Epigenetic Reader Domain
BI-9564, a specific cell-permeable BRD9 BD inhibitor. The Kd for BRD9 is 5.9 nM, and IC50 for BET family is > 100 μM.
T9703 GSK778 Epigenetic Reader Domain
GSK778 is a potent and selective inhibitor of BD1 bromodomain such as BRD2 BD1 (IC50s = 75 nM), BRD3 BD1 (IC50s = 41 nM), BRD4 BD1 (IC50s = 41 nM), and BRDT BD1 (IC50s = 143 nM). GSK778 inhibits proliferation, induces a ...
T6026 CPI-203 CPI 203,CPI203 Apoptosis , Epigenetic Reader Domain
CPI-203 is an effective BET bromodomain inhibitor (IC50: 37 nM for BRD4).
T15405 GNE-781 Epigenetic Reader Domain
GNE-781 is a highly potent and selective inhibitor of CBP (IC50: 0.94 nM in TR-FRET assay). GNE-781 also inhibits BRET and BRD4(1) (IC50s: 6.2 nM and 5100 nM, respectively).
T14073 A-485 Epigenetic Reader Domain , Histone Acetyltransferase
A-485 is a potent and selective catalytic p300/CBP inhibitor(IC50s of 9.8 nM and 2.6 nM for p300 and CBP, respectively).
T5318 666-15 CREB inhibitor Epigenetic Reader Domain
666-15 (CREB inhibitor) is a potent and selective CREB inhibitor (IC50: 81 nM).
T15216 EML 425 Epigenetic Reader Domain , Histone Acetyltransferase
EML 425 is a potent and selective inhibitor of CREB binding protein (CBP)/p300 (IC50s: 2.9 and 1.1 μM, respectively).
T17350 ACBI1 Apoptosis , Epigenetic Reader Domain , PROTACs
ACBI1 is a potent PROTAC degrader of BAF ATPase subunits SMARCA2 and SMARCA4, also degrades the polybromo-associated BAF (PBAF) complex member PBRM1, with DC50s of 6 nM, 11 nM and 32 nM for SMARCA2, SMARCA4 and PBRM1 in ...
T14776 BRD4 Inhibitor-10 Epigenetic Reader Domain
BRD4 Inhibitor-10 is an inhibitor of BRD4-BD1 (IC50: 8 nM).
T9194 UMB298 Epigenetic Reader Domain
UMB298 is a potent and selective CBP/P300 bromodomain inhibitor. UMB298 inhibits BRD4 with IC50 of 5193nM.
T9629 BRD4 Inhibitor-24 Epigenetic Reader Domain
BRD4 Inhibitor-24 is a BRD4 small molecule inhibitor with antitumor activity.
T8890 653-47 hydrochloride Epigenetic Reader Domain
653-47 hydrochloride is a potentiator, significantly potentiates the cAMP-response element binding protein (CREB) inhibitory activity of 666-15. It is also a very weak CREB inhibitor with IC50 of 26.3 μM.
T4345 CeMMEC1 CeMMEC1 HCl Epigenetic Reader Domain , Carboxypeptidase , DNA/RNA Synthesis
CeMMEC1 is an inhibitor of BRD4, and also has a great affinity for TAF1(IC50=0.9 μM).
T7264 CBP/EP300-IN-1 Epigenetic Reader Domain
CBP/EP300-IN-1 is a CBP/EP300 bromodomain inhibitor.

Compounds

Epigenetic Multiple Ligand
T72013
Synonym:
Target:
Epigenetic factor-IN-1
T82458
Synonym:
Target: Sirtuin
GSK1379725A
T15424
Synonym:
Target: Epigenetic Reader Domain
BET bromodomain inhibitor
T2072
Synonym:
Target: Epigenetic Reader Domain
M‑89
T11925
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
Dbet57
T5440
Synonym:
Target: Epigenetic Reader Domain
dBET1
T4495
Synonym:
Target: Epigenetic Reader Domain
SGC-CBP30
T6668
Synonym:
Target: Epigenetic Reader Domain, Histone Acetyltransferase
dBET6
T5130
Synonym:
Target: Apoptosis, Epigenetic Reader Domain
MS436
T1854
Synonym:
Target: Epigenetic Reader Domain
GSK6853
T3311
Synonym:
Target: Epigenetic Reader Domain
MI-463
TQ0058
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
MI-538
T16072
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
Y06036
T5362
Synonym:
Target: Epigenetic Reader Domain
XD14
T19935
Synonym:
Target: Epigenetic Reader Domain
PF-CBP1
T3973
Synonym:
Target: Epigenetic Reader Domain
BMS-986158
T14685
Synonym:
Target: Epigenetic Reader Domain
Y06137
T13363
Synonym:
Target: Epigenetic Reader Domain, PKC
BI-7273
T6783
Synonym:
Target: Epigenetic Reader Domain
NI-57
TQ0083
Synonym:
Target: Epigenetic Reader Domain
PLX51107
TQ0253
Synonym:
Target: Epigenetic Reader Domain
MS402
T12112
Synonym:
Target: Epigenetic Reader Domain
MI-503
TQ0069
Synonym:
Target: Epigenetic Reader Domain, Histone Methyltransferase
NI-42
T16321
Synonym:
Target: Epigenetic Reader Domain
FHD-286
T9749
Synonym:
Target: Epigenetic Reader Domain
OF-1
T2127
Synonym:
Target: Epigenetic Reader Domain
BRD7-IN-1
T17697
Synonym:
Target: Epigenetic Reader Domain
E-7386
T11136
Synonym: E7386
Target: Epigenetic Reader Domain
(+)-JQ1 PA
T17311
Synonym:
Target: Epigenetic Reader Domain
SGC-SMARCA-BRDVIII
T9568
Synonym:
Target: Epigenetic Reader Domain
INCB-057643
T5417
Synonym:
Target: Apoptosis, Epigenetic Reader Domain
ARV-825
T5434
Synonym:
Target: Epigenetic Reader Domain
A1874
T5442
Synonym:
Target: Epigenetic Reader Domain, PROTACs
ARV-771
T5435
Synonym:
Target: Epigenetic Reader Domain
PFI-3
T6939
Synonym: PFI 3
Target: Epigenetic Reader Domain
A-366
T3624
Synonym: A 366,A366
Target: Epigenetic Reader Domain, Histone Methyltransferase
BI-9564
T6786
Synonym: BI 9564,BI9564
Target: Epigenetic Reader Domain
GSK778
T9703
Synonym:
Target: Epigenetic Reader Domain
CPI-203
T6026
Synonym: CPI 203,CPI203
Target: Apoptosis, Epigenetic Reader Domain
GNE-781
T15405
Synonym:
Target: Epigenetic Reader Domain
A-485
T14073
Synonym:
Target: Epigenetic Reader Domain, Histone Acetyltransferase
666-15
T5318
Synonym: CREB inhibitor
Target: Epigenetic Reader Domain
EML 425
T15216
Synonym:
Target: Epigenetic Reader Domain, Histone Acetyltransferase
ACBI1
T17350
Synonym:
Target: Apoptosis, Epigenetic Reader Domain, PROTACs
BRD4 Inhibitor-10
T14776
Synonym:
Target: Epigenetic Reader Domain
UMB298
T9194
Synonym:
Target: Epigenetic Reader Domain
BRD4 Inhibitor-24
T9629
Synonym:
Target: Epigenetic Reader Domain
653-47 hydrochloride
T8890
Synonym:
Target: Epigenetic Reader Domain
CeMMEC1
T4345
Synonym: CeMMEC1 HCl
Target: Epigenetic Reader Domain, Carboxypeptidase, DNA/RNA Synthesis
CBP/EP300-IN-1
T7264
Synonym:
Target: Epigenetic Reader Domain
1 2 3
Cat No. Product Name Synonyms Targets
T6389 Anacardic Acid 6-pentadecylsalicylic Acid,Hydroginkgolic acid Others , Epigenetic Reader Domain , Histone Acetyltransferase , Antibacterial
Anacardic Acid (6-pentadecylsalicylic Acid) is an effective inhibitor of p300 and p300/CBP-associated factor histone acetyltranferases. It also has antimicrobial activity, antibacterial activity, and inhibits prostagland...
T1516 Curcumin Diferuloylmethane,Natural Yellow 3,Indian Saffron,Turmeric yellow Mitophagy , Epigenetic Reader Domain , Ferroptosis , Influenza Virus , Nrf2 , Histone Acetyltransferase , HDAC , Autophagy
Curcumin (Natural Yellow 3) is a phenolic natural product, an inhibitor of histone acetyltransferase p300/CREB (IC50=25 μM) with specificity. Curcumin has a wide range of pharmacological activities such as antitumor, ant...
T5270 5-Methylcytosine Others , DNA/RNA Synthesis , Endogenous Metabolite
5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals, the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In plants, the methylated...
T19127 3-Phosphoglyceric acid Others
3-Phosphoglyceric acid is a metabolic intermediate in both glycolysis and the Calvin cycle. It is involved in alveolar macrophage epigenetic regulation.
T66903 Gallic Acid Monohydrate
Gallic acid may be used as a standard in the photometric determination of total phenolics content by Folin-Ciocalteu method with potential role in epigenetic therapy of human cancers.
T13749 L-2-Hydroxyglutaric acid (S)-2-Hydroxyglutaric acid Others
L-2-Hydroxyglutaric acid, an epigenetic modifier and potential oncometabolite in renal cancer, impedes mitochondrial creatine kinase (Mi-CK) activity, exhibiting Km and Ki values of 2.52 mM and 11.13 mM, respectively. Ad...

Natural Products

Anacardic Acid
T6389
Synonym: 6-pentadecylsalicylic Acid,Hydroginkgolic acid
Target: Others, Epigenetic Reader Domain, Histone Acetyltransferase, Antibacterial
Curcumin
T1516
Synonym: Diferuloylmethane,Natural Yellow 3,Indian Saffron,Turmeric yellow
Target: Mitophagy, Epigenetic Reader Domain, Ferroptosis, Influenza Virus, Nrf2, Histone Acetyltransferase, HDAC, Autophagy
5-Methylcytosine
T5270
Synonym:
Target: Others, DNA/RNA Synthesis, Endogenous Metabolite
3-Phosphoglyceric acid
T19127
Synonym:
Target: Others
Gallic Acid Monohydrate
T66903
Synonym:
Target:
L-2-Hydroxyglutaric acid
T13749
Synonym: (S)-2-Hydroxyglutaric acid
Target: Others

Recombinant Proteins

Species：
Human (27)
Mouse (4)
Arabidopsis thaliana (1)
Sus scrofa (Pig) (1)
Expression System：
E. coli (14)
Baculovirus-Insect Cells (11)
HEK293 (4)
Yeast (2)
Baculovirus (1)
Human Cells (1)
Tag：
His (12)
GST (3)
His,GST (3)
Tag Free (3)
N-terminal 10xHis-tagged and C-terminal Myc-tagged (2)
N-terminal 6xHis-SUMO-tagged (2)
N-terminal 6xHis-tagged (2)
(1)
C-mFc (1)
N-10His-Flag (1)
Cat No. Product Name Species Expression System
TMPY-00365 GALNT7 Protein, Human, Recombinant (His) Human HEK293
GalNAc-transferase-7 (GALNT7) is essential for the regulation of cell proliferation and has been implicated in tumorigenesis. Colorectal cancer (CRC) arises in a multistep molecular network process, which is from either ...
TMPY-01478 HSP90 alpha Protein, Human, Recombinant Human E. coli
Heat shock protein 90 (90 kDa heat-shock protein, HSP90) is a molecular chaperone involved in the trafficking of proteins in the cell. It is a remarkably versatile protein involved in the stress response and normal homoe...
TMPY-02030 CD82 Protein, Human, Recombinant (His) Human HEK293
CD82, also known as KAI-1, structurally belongs to tetraspanin family while categorised as metastasis suppressor gene on functional grounds. KAI1/CD82 is localized on cell membrane and form interactions with other tetras...
TMPH-00095 HDT2 Protein, Arabidopsis thaliana, Recombinant (His) Arabidopsis thaliana Yeast
Probably mediates the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcr...
TMPJ-00694 BRD4 Protein, Human, Recombinant (His & Flag) Human E. coli
Bromodomain-containing protein 4 (BRD4) is a member of the BET class chromatin reader proteins that bind acetylated histones and play a key role in transcriptional regulation and transmission of epigenetic memory. Remain...
TMPY-02378 14‑3‑3 theta/YWHAQ Protein, Human, Recombinant (GST) Human E. coli
The recently identified 14-3-3 tau, whose corresponding gene name is YWHAQ, is in a hypoxia-treated human trophoblast cell line. YWHAQ may play a role in epigenetic regulation of placental genes in the onset of Preeclamp...
TMPH-02908 AICDA Protein, Mouse, Recombinant (His & Myc) Mouse E. coli
Single-stranded DNA-specific cytidine deaminase. Involved in somatic hypermutation (SHM), gene conversion, and class-switch recombination (CSR) in B-lymphocytes by deaminating C to U during transcription of Ig-variable (...
TMPK-00710 Claudin-4 Protein-VLP, Human, Recombinant Human HEK293
Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been asso...
TMPH-01088 CBX5 Protein, Human, Recombinant (His & Myc) Human E. coli
Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphor...
TMPH-02175 TAF5L Protein, Human, Recombinant (GST) Human E. coli
Functions as a component of the PCAF complex. The PCAF complex is capable of efficiently acetylating histones in a nucleosomal context. The PCAF complex could be considered as the human version of the yeast SAGA complex....
TMPH-02311 WDR5 Protein, Human, Recombinant (His & SUMO) Human E. coli
Contributes to histone modification. May position the N-terminus of histone H3 for efficient trimethylation at 'Lys-4'. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histon...
TMPY-01464 USP7 Protein, Human, Recombinant (aa 208-560) Human Baculovirus-Insect Cells
Ubiquitin carboxyl-terminal hydrolase 7, also known as Ubiquitin thioesterase 7, Herpesvirus-associated ubiquitin-specific protease, Ubiquitin-specific-processing protease 7, USP7 and HAUSP, is a widely expressed protein...
TMPY-01465 USP7 Protein, Human, Recombinant (His & GST) Human Baculovirus-Insect Cells
Ubiquitin carboxyl-terminal hydrolase 7, also known as Ubiquitin thioesterase 7, Herpesvirus-associated ubiquitin-specific protease, Ubiquitin-specific-processing protease 7, USP7 and HAUSP, is a widely expressed protein...
TMPH-01235 APOBEC3A Protein, Human, Recombinant (His & SUMO) Human E. coli
DNA deaminase (cytidine deaminase) with restriction activity against viruses, foreign DNA and mobility of retrotransposons. Exhibits antiviral activity against adeno-associated virus (AAV) and human T-cell leukemia virus...
TMPY-01463 USP7 Protein, Human, Recombinant (aa 208-560, His & GST) Human Baculovirus-Insect Cells
Ubiquitin carboxyl-terminal hydrolase 7, also known as Ubiquitin thioesterase 7, Herpesvirus-associated ubiquitin-specific protease, Ubiquitin-specific-processing protease 7, USP7 and HAUSP, is a widely expressed protein...
TMPJ-00986 CTCF Protein, Human, Recombinant Human E. coli
Transcriptional Repressor CTCF (CTCF) belongs to the CTCF Zinc-Finger Protein family. CTCF contains twelve C2H2-type zinc fingers and interacts with CHD8. CTCF is widely expressed in many tissues, and it is absent in pri...
TMPY-02573 IL-17RC Protein, Human, Recombinant (aa 1-454, His) Human Baculovirus-Insect Cells
IL17RC (Interleukin 17 Receptor C) is a Protein Coding gene. This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). IL17RC is widely expressed in the pr...
TMPY-03332 PRTFDC1 Protein, Human, Recombinant (His) Human E. coli
PRTFDC1 is a member of the purine/pyrimidine phosphoribosyltransferase family. It can bind GMP, IMP and alpha-D-5-phosphoribosyl 1-pyrophosphate (PRPP). The epigenetic silencing of PRTFDC1 by hypermethylation of the CpG ...
TMPY-00519 Gastrokine 1 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Gastrokine 1 (GKN1) belongs to the BRICHOS domain family and plays a major role in maintaining gastric mucosa integrity. GKN1 is highly expressed in gastric tissue and is secreted into the stomach but is not expressed in...
TMPY-02691 IL-17RC Protein, Human, Recombinant(aa 1-454, hFc) Human HEK293
IL17RC (Interleukin 17 Receptor C) is a Protein Coding gene. This gene encodes a single-pass type I membrane protein that shares similarity with the interleukin-17 receptor (IL-17RA). IL17RC is widely expressed in the pr...
TMPJ-00790 GSN Protein, Human, Recombinant (mFc) Human Human Cells
Gelsolin is a calcium-activated actin filament severing and capping protein found in many cell types and as a secreted form in the plasma of vertebrates. Gelsolin is composed of six of these domains, termed G1-6. Some re...
TMPY-02979 HMGN3 Protein, Human, Recombinant (His) Human E. coli
HMGN3 belongs to the HMGN family and is expressed in the kidney, lung, pancreas, testis, skeletal muscle, heart, thyroid gland, pituitary gland, prostate, and uterus. Members of the HMGN family bind to nucleosomes withou...
TMPY-06752 HK2 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Hexokinase 2 (HK2), a rate-limiting enzyme in the first step of the glycolysis pathway, expresses at a high level in cancer cells compared with normal cells. HK2 provides a new target for cancer therapy due to its pivota...
TMPY-06763 HK2 Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Hexokinase 2 (HK2), a rate-limiting enzyme in the first step of the glycolysis pathway, expresses at a high level in cancer cells compared with normal cells. HK2 provides a new target for cancer therapy due to its pivota...
TMPY-02957 DYDC2 Protein, Human, Recombinant (GST) Human E. coli
DPY30 domain containing 2 belongs to the dpy-30 family. Dumpy-30 family members act as determinants of male fertility and interaction partners of metal-responsive transcription factor 1 (MTF-1) in Drosophila. MTF-1 plays...
TMPY-01657 SUV420H2 Protein, Human, Recombinant (His & GST) Human E. coli
Histone-lysine N-methyltransferase SUV42H2, also known as Suppressor of variegation 4-2 homolog 2, Su(var)4-2 homolog 2, Lysine N-methyltransferase 5C, SUV42H2 and KMT5C, is nucleus protein that belongs to the histone-ly...
TMPY-02317 HDAC8 Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Histone deacetylase 8, also known as HDAC8 and HDACL1, is a nucleus and cytoplasm protein that belongs to the histone deacetylase family and HD type 1 subfamily. Histone deacetylases (HDACs) are a growing family of enzym...
TMPY-06845 HSP90 alpha Protein, Human, Recombinant (His) Human Baculovirus-Insect Cells
Heat shock protein 90 (90 kDa heat-shock protein, HSP90) is a molecular chaperone involved in the trafficking of proteins in the cell. It is a remarkably versatile protein involved in the stress response and normal homoe...
TMPY-01333 HDAC8 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
Histone deacetylase 8, also known as HDAC8 and HDACL1, is a nucleus and cytoplasm protein that belongs to the histone deacetylase family and HD type 1 subfamily. Histone deacetylases (HDACs) are a growing family of enzym...
TMPY-06846 HSP90 alpha Protein, Mouse, Recombinant (His) Mouse Baculovirus-Insect Cells
Heat shock protein 90 (90 kDa heat-shock protein, HSP90) is a molecular chaperone involved in the trafficking of proteins in the cell. It is a remarkably versatile protein involved in the stress response and normal homoe...
TMPY-00585 Annexin A8 Protein, Human, Recombinant (His) Human E. coli
We have previously shown that Annexin A8 (ANXA8) is strongly associated with the basal-like subgroup of breast cancers, including BRCA1-associated breast cancers, and poor prognosis; while in the mouse mammary gland AnxA...
TMPY-00150 IGF2/IGF-II Protein, Human, Recombinant Human Yeast
Insulin-like growth factor 2 (IGF-2/IGF-II) is a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele,...
TMPH-03113 HSP90AA1 Protein, Pig, Recombinant (His) Sus scrofa (Pig) Baculovirus
Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle...
GALNT7 Protein, Human, Recombinant (His)
TMPY-00365
Species: Human
Expression System: HEK293
HSP90 alpha Protein, Human, Recombinant
TMPY-01478
Species: Human
Expression System: E. coli
CD82 Protein, Human, Recombinant (His)
TMPY-02030
Species: Human
Expression System: HEK293
HDT2 Protein, Arabidopsis thaliana, Recombinant (His)
TMPH-00095
Species: Arabidopsis thaliana
Expression System: Yeast
BRD4 Protein, Human, Recombinant (His & Flag)
TMPJ-00694
Species: Human
Expression System: E. coli
14‑3‑3 theta/YWHAQ Protein, Human, Recombinant (GST)
TMPY-02378
Species: Human
Expression System: E. coli
AICDA Protein, Mouse, Recombinant (His & Myc)
TMPH-02908
Species: Mouse
Expression System: E. coli
Claudin-4 Protein-VLP, Human, Recombinant
TMPK-00710
Species: Human
Expression System: HEK293
CBX5 Protein, Human, Recombinant (His & Myc)
TMPH-01088
Species: Human
Expression System: E. coli
TAF5L Protein, Human, Recombinant (GST)
TMPH-02175
Species: Human
Expression System: E. coli
WDR5 Protein, Human, Recombinant (His & SUMO)
TMPH-02311
Species: Human
Expression System: E. coli
USP7 Protein, Human, Recombinant (aa 208-560)
TMPY-01464
Species: Human
Expression System: Baculovirus-Insect Cells
USP7 Protein, Human, Recombinant (His & GST)
TMPY-01465
Species: Human
Expression System: Baculovirus-Insect Cells
APOBEC3A Protein, Human, Recombinant (His & SUMO)
TMPH-01235
Species: Human
Expression System: E. coli
USP7 Protein, Human, Recombinant (aa 208-560, His & GST)
TMPY-01463
Species: Human
Expression System: Baculovirus-Insect Cells
CTCF Protein, Human, Recombinant
TMPJ-00986
Species: Human
Expression System: E. coli
IL-17RC Protein, Human, Recombinant (aa 1-454, His)
TMPY-02573
Species: Human
Expression System: Baculovirus-Insect Cells
PRTFDC1 Protein, Human, Recombinant (His)
TMPY-03332
Species: Human
Expression System: E. coli
Gastrokine 1 Protein, Human, Recombinant (His)
TMPY-00519
Species: Human
Expression System: Baculovirus-Insect Cells
IL-17RC Protein, Human, Recombinant(aa 1-454, hFc)
TMPY-02691
Species: Human
Expression System: HEK293
GSN Protein, Human, Recombinant (mFc)
TMPJ-00790
Species: Human
Expression System: Human Cells
HMGN3 Protein, Human, Recombinant (His)
TMPY-02979
Species: Human
Expression System: E. coli
HK2 Protein, Mouse, Recombinant (His)
TMPY-06752
Species: Mouse
Expression System: Baculovirus-Insect Cells
HK2 Protein, Human, Recombinant (His)
TMPY-06763
Species: Human
Expression System: Baculovirus-Insect Cells
DYDC2 Protein, Human, Recombinant (GST)
TMPY-02957
Species: Human
Expression System: E. coli
SUV420H2 Protein, Human, Recombinant (His & GST)
TMPY-01657
Species: Human
Expression System: E. coli
HDAC8 Protein, Mouse, Recombinant (His)
TMPY-02317
Species: Mouse
Expression System: Baculovirus-Insect Cells
HSP90 alpha Protein, Human, Recombinant (His)
TMPY-06845
Species: Human
Expression System: Baculovirus-Insect Cells
HDAC8 Protein, Human, Recombinant (GST)
TMPY-01333
Species: Human
Expression System: Baculovirus-Insect Cells
HSP90 alpha Protein, Mouse, Recombinant (His)
TMPY-06846
Species: Mouse
Expression System: Baculovirus-Insect Cells
Annexin A8 Protein, Human, Recombinant (His)
TMPY-00585
Species: Human
Expression System: E. coli
IGF2/IGF-II Protein, Human, Recombinant
TMPY-00150
Species: Human
Expression System: Yeast
HSP90AA1 Protein, Pig, Recombinant (His)
TMPH-03113
Species: Sus scrofa (Pig)
Expression System: Baculovirus
Cat No. Product Name
L1200 Epigenetics Compound Library

960 compounds
Well-chosen 960 compounds related to epigenetic regulation for research in epigenetics, high throughput screening (HTS) and high content screening (HCS) for new drugs;
L3500 Histone Modification Compound Library

480 compounds
A unique collection of 480 histone modification related compounds for high throughput screening (HTS) and high content screening (HCS);
L8300 Chromatin Modification Compound Library

256 compounds
A unique collection of 256 compounds targeting chromatin remodeling pathway for high throughput screening (HTS) and high content screening (HCS);
L8200 Anti-Aging Compound Library

3324 compounds
A unique collection of 3324 anti-aging compounds for high throughput screening (HTS) and high content screening (HCS);
L2140 Cancer Cell Differentiation Compound Library

413 compounds
A unique collection of 413 cancer cell differentiation inducing compounds for high throughput and high content screening;

Libraries

Epigenetics Compound Library
L1200
Compounds: 960
Histone Modification Compound Library
L3500
Compounds: 480
Chromatin Modification Compound Library
L8300
Compounds: 256
Anti-Aging Compound Library
L8200
Compounds: 3324
Cancer Cell Differentiation Compound Library
L2140
Compounds: 413
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