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Search Results for " dna/rna synthesis "

20

Compounds

Cat No. Product Name Synonyms Targets
T12019 Methylproamine Others
Methylproamine is a DNA-binding radioprotector , acts by repair of transient radiation-induced oxidative species on DNA.
T13969 Xanthopterin (hydrate) Others , DNA/RNA Synthesis
Xanthopterin Hydrate is isolated from butterfly wings and could replace folic acid in the nutrition of many animal species.
T21498 Phleomycin DNA/RNA Synthesis , Antibacterial , Antibiotic
Phleomycin is one of the anticancer glycopeptide antibiotics which cause DNA cleavage. It is similar to Bleomycin which binds and intercalates DNA to damage the integrity of the double helix.
T14522 Beaucage reagent DNA/RNA Synthesis
Beaucage reagent, which is found to be effective in causing DNA cleavage.
T36757 DMT-dU-CE Phosphoramidite DNA/RNA Synthesis
DMT-dU-CE Phosphoramidite is a nucleoside molecule commonly used for the synthesis and sequencing of DNA.
T8873 Bractoppin Others , DNA/RNA Synthesis
Bractoppin is a drug-like inhibitor of phosphopeptide recognition by the human BRCA1 tandem (t)BRCT domain (IC50 = 0.074 μM), which selectively inhibits substrate binding with nanomolar potency in vitro. Structure-activi...
T40179 Sodium Camptothecin DNA/RNA Synthesis
Sodium Camptothecin is a plant alkaloid with antitumor activity. Sodium Camptothecin is a reversible RNA synthesis inhibitor. Sodium Camptothecin is an effective adenovirus replication inhibitor. Sodium Camptothecin i...
TP1115 L-Asparaginase L-​ASNase Others
L-Asparaginase (L-ASNase) (L-ASNase), a hydrolase that catalyzes the conversion of L-asparagine, used in acute lymphoblastic leukemia treatment.Asparaginase is an enzyme that is used as a medication. As a medication, L-a...
T7520 Deoxycytidine triphosphate Nucleoside Antimetabolite/Analog , DNA/RNA Synthesis , Endogenous Metabolite
Deoxycytidine triphosphate is a nucleoside triphosphate.It is a raw material in DNA synthesis. Deoxycytidine triphosphate has many applications, such as real-time PCR, cDNA synthesis, and DNA sequencing.
T6801 CeMMEC13 Carboxypeptidase , DNA/RNA Synthesis
CeMMEC13 is an isoquinolinone that selectively inhibits the second bromodomain of TAF1 (IC50 = 2.1 μM).
T1154 Rifaximin DNA/RNA Synthesis , Antibacterial , Antibiotic
Rifaximin is an orally administered, semi-synthetic, nonsystemic antibiotic derived from rifamycin SV with antibacterial activity. Rifaximin binds to the beta-subunit of bacterial DNA-dependent RNA polymerase, inhibiting...
T2S1635 3-Isomangostin MTH1
3-Isomangostin is a potent human aldose reductase inhibitor with an IC50 of 3.48 uM; it is also an acetylcholinesterase selective inhibitor. 3-Isomangostin has free radical scavenging activity; it shows antiplasmodial ac...
T8354 Triazavirin Nucleoside Antimetabolite/Analog , Influenza Virus , DNA/RNA Synthesis
Triazavirin is a nucleoside analogue of nucleic acid and an antiviral agent.
T15611 JH-RE-06 DNA/RNA Synthesis
JH-RE-06 disrupts mutagenic translesion synthesis (TLS) by preventing the recruitment of mutagenic POLζ. JH-RE-06 is an effective REV1-REV7 interface inhibitor (IC50=0.78 μM; Kd=0.42 μM), which targets REV1 that interact...
T37101 1-Hydroxyanthraquinone DNA/RNA Synthesis
1-Hydroxyanthraquinone is an anthraquinone that has been found in Morinda officinalis and has genotoxic and carcinogenic activities. 1-Hydroxyanthraquinone generates strong DNA repair response.
T1767 BMH-21 BMH21 DNA/RNA Synthesis
BMH-21, a small molecule DNA intercalator, binds ribosomal DNA and inhibits RNA polymerase I (Pol I) transcription and not affects phosphorylation of H2AX.
TN1134 Euscaphic acid Apoptosis , LDL , PI3K , DNA/RNA Synthesis , NO Synthase , Prostaglandin Receptor
Euscaphic acid has anti-diabetic, and anti-inflammatory activities, it inhibits LPS-induced inflammatory responses by interference with the clustering of TRAF6 with IRAK1 and TAK1, resulting in blocking the activation of...
T36756 DMT-dG(ib) Phosphoramidite DNA/RNA Synthesis
DMT-dG(ib) Phosphoramidite can be used to synthesize DNA.
T5901 3-Hydroxy-2-methylpyridine Others
3-Hydroxy-2-methylpyridine could as a promising molecular scaffold for the future development of novel fibrillization inhibitors.
T5270 5-Methylcytosine Others , DNA/RNA Synthesis , Endogenous Metabolite
5-Methylcytosine is a methylated nucleotide base found in eukaryotic DNA. In animals, the DNA methylation of cytosine to form 5-methylcytosine is found primarily in the palindromic sequence CpG. In plants, the methylated...
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