non-selective — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T8580	Bupranolol		Adrenergic Receptor
	Bupranolol is an antagonist of β2-adrenergic receptor and has been used for angina pectoris, hypertension, glaucoma, cardiac arrhythmia and as an antithrombotic.		Adrenergic Receptor
T7538	Tetraethylammonium chloride		Potassium Channel
	Tetraethylammonium chloride is a quaternary ammonium compound. It is a non-selective potassium channel blocker. It is a good substrate for organic cation transporter proteins and has antitumor properties.		Potassium Channel
T3474	RO 46-8443		Endothelin Receptor
	RO 46-8443 is the first non-peptide endothelin ETB receptor selective antagonist. RO 46-8443 displays up to 2000-fold selectivity for ETB receptors both in terms of binding inhibitory potency and functional inhibition.		Endothelin Receptor
T8459	DNQX disodium salt	DNQX Disodium	NMDAR , iGluR
	DNQX disodium salt is a water-soluble form of selective antagonist of non-NMDA receptor		NMDAR , iGluR
T7304	DNQX	FG 9041	GluR , iGluR
	DNQX (FG 9041) is a competitive, non-NMDA glutamate receptor antagonist (IC50s = 0.5 and 0.1 μM for AMPA and kainate receptors, respectively)		GluR , iGluR
T60076	Oritinib	SH-1028	EGFR
	Oritinib (SH-1028) is an inhibitor of EGFR with IC50s of 18, 0.7, 4, 0.1, 1.4 and 0.89 nM for EGFR (wt), EGFR (L858R), EGFR (L861Q), EGFR (L858R/T790M), EGFR (d746-750), EGFR (d746-750/T790M), respectively. Oritinib can ...		EGFR
T9245	TRPM4-IN-1	CBA,4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid	TRP/TRPV Channel
	TRPM4-IN-1 (4-chloro-2-(2-(2-chlorophenoxy)acetamido)benzoic acid) is a potent and selective inhibitor of TRPM4 with an IC50 of 1.5 μM.		TRP/TRPV Channel
T10774	CFM-2		iGluR
	CFM-2, a potent and selective non-competitive antagonist of AMPAR (AMPAR), exhibits anticonvulsant activity across various seizure models.		iGluR
T16778	Rocastine	AHR-11325	Histamine Receptor
	Rocastine (AHR-11325) is a selective and potent non-sedating H1 receptor antagonist.		Histamine Receptor
T9967	MAGL-IN-5		Lipid
	MAGL-IN-5 is a non-selective lipase inhibitor.		Lipid
T22346	Indomethacin sodium hydrate	Indometacin Sodium	COX
	Indomethacin Sodium is the sodium salt of indomethacin, which is a non-selective, competitive, and reversible, inhibitor of cyclooxygenases 1 and 2 with analgesic-antipyretic, anti-inflammatory, and tocolytic effects.		COX
T23306	Salvinorin A		Opioid Receptor
	Salvinorin A is a non-nitrogenous κ-opioid selective agonist.		Opioid Receptor
T29096	Vapitadine dihydrochloride	Vapitadine 2HCl,R129160,R-129160 2HCl,Vapitadine HCl,R 129160 2HCl,R-129160,R 129160,R129160 2HCl	Histamine Receptor
	Vapitadine dihydrochloride(R-129160 2HCl) is a novel, potent, selective and non-sedating compound with inhibitory effects on histamine H1.		Histamine Receptor
T22092	Indomethacin heptyl ester		COX
	Indomethacin heptyl ester is a non-selective inhibitor of both COX-1 and COX-2		COX
T35898	Izencitinib
	Izencitinib (TD-1473) is an orally active, gut-restricted JAK inhibitor with non-selective properties. It is primarily employed in the investigation of ulcerative colitis [1].
TP1929L1	Saralasin acetate(34273-10-4 free base)		RAAS
	Saralasin acetate is a Non-selective angiotensin II antagonist.		RAAS
T2362	QNZ46		NMDAR , iGluR
	QNZ46 is a NR2C/NR2D-selective NMDA receptor non-competitive antagonist.		NMDAR , iGluR
T0327	Fendiline hydrochloride	Fendiline HCl	Calcium Channel
	Fendiline hydrochloride (Fendiline HCl) is a non-selective blocker of calcium channel.		Calcium Channel
T13689	Ethylene dimethanesulfonate		Apoptosis
	Ethylene dimethanesulfonate has selective pro-apoptotic effects on LCs. Ethylene dimethanesulfonate is a mild alkylating, non-volatile methanesulfonic diester of ethylene glycol.		Apoptosis
T22692	CPCCOEt		GluR
	CPCCOEt is a low affinity, selective, non-competitive and reversible antagonist of mGluR1b		GluR