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Search Results for " mmp "

20

Compounds

Cat No. Product Name Synonyms Targets
T21512 MMP-2/MMP-9 Inhibitor I MMP
MMP-2/MMP-9-IN-1 is a potent, highly selective and orally bioavailable inhibitor of type IV collagenases (MMP-9 and MMP-2) with an IC50 of 0.24 and 0.3 1 μM for MMP-9 and MMP-2, respectively. activity, which can be used ...
T37048 MMP-3 Inhibitor MMP
MMP-3 Inhibitor is a peptide matrix metalloproteinase-3 (MMP-3) inhibitor with a Ki value of 95 nM.MMP-3 inhibitor has anticancer and antitumor activity.
T36712 BPHA MMP-2/MMP-9 Inhibitor II MMP
BPHA (MMP-2/MMP-9 Inhibitor II) is a potent, selective and orally active inhibitor of MMP-2, MMP-9 and MMP-14 with IC50s of 12 nM, 16 nM and 17 nM, respectively.BPHA does not inhibit MMP-1, -3 and -7 (IC50s of 974, >1000...
T8310 MMP-9-IN-1 MMP
MMP-9-IN-1 is an inhibitor of specific matrix metalloproteinase-9 (MMP-9).
T77617 MMP-9-IN-6 MMP
MMP-9-IN-6 is an MMP-9 inhibitor with an IC50 value of 50 μM and good anti-ulcer efficacy.MMP-9-IN-6 has potential anti-tumor activity and can be used to study tissue remodeling, wound repair and atherosclerosis.
T78181 MMP-7-IN-2 MMP , Others
MMP-7-IN-2 acts as a selective and potent MMP7 inhibitor and can be used to study inflammatory responses and vascular-related diseases.
T72069 MMP-9-IN-7
Acetamide, N-[2-[(5-chloro-2 methoxyphenyl)amino]-4'-methyl[4,5'-bithiazol]-2'-yl]-inhibits pro-matrix metalloproteinase activation and can be used to prevent, treat or ameliorate MMP9 and/or MMP13-mediated syndromes.
T15055 DB04760 MMP-13 Inhibitor MMP
DB04760 is a highly selective, non-zinc-chelating inhibitor of MMP-13 (IC50: 8 nM). DB04760 obviously decreases paclitaxel neurotoxicity and has anticancer activity.
T14322 ARP-100 MMP-2 Inhibitor III MMP
ARP-100 (MMP-2 Inhibitor III) is a potent and selective matrix metalloproteinase MMP-2 inhibitor (IC50=12 nM). ARP-100 interacts with the S1' pocket of MMP-2 and exhibits anti-invasive properties in an in vitro invasion ...
T37048L MMP-3 Inhibitor acetate MMP-3 Inhibitor acetate(158841-76-0 Free base) MMP
MMP-3 Inhibitor acetate is a cell-permeable and potent inhibitor of human MMP-3.
T37172 MMP-9/MMP-13 Inhibitor I
MMP-9/MMP-13 Inhibitor I is a dual inhibitor of MMP-9 and MMP-13 with IC50 of both 0.9 nM. MMP-9/MMP-13 Inhibitor I is over 20 times more selective for MMP-9/MMP-13 than other MMPs.
T60083 MMP-12 Inhibitor MMP12,MMP408 MMP
MMP-12 Inhibitor is a selective inhibitor of MMP-12 with IC50s of 2, 160, 320, and 22.3 nM for human, mouse, rat, and sheep MMP-12.
T25825 MMP-145
MMP-145 is used as a protease inhibitor.
T37726 MMP-9 Inhibitor I
MMP-9 inhibitor I is an inhibitor of matrix metalloproteinase-9 (MMP-9) that is selective over MMP-1 and MMP-13 (IC50s = 5, 1,050, and 113 nM, respectively). It also decreases the activity of TNF-α converting enzyme (TAC...
T36962 MMP Inhibitor I (trifluoroacetate salt)
MMP inhibitor I is a peptide inhibitor of matrix metalloproteinase-1 (MMP-1), MMP-2, and MMP-3 (IC50s = 1.3, 30, and 150 μM, respectively). It is selective for MMP-1, MMP-2, and MMP-3 over the proteases thermolysin, urea...
T69666 MMP-8 Inhibitor I
MMP-8 Inhibitor I is a selective inhibitor of the neutrophil collagenase matrix metalloproteinase-8 (MMP-8) with an IC50 value of 4 nM.
T76077 MMP-13 Substrate
MMP-13 Substrate, a compound utilized in osteoarthritis (OA) research [1], functions as a substrate for MMP-13.
T16124 MMP13-IN-3 MMP
MMP13-IN-3 is >1000 selective over other MMPs. MMP13-IN-3 is an effective, selective, and orally active MMP-13 inhibitor (IC50=1 nM) for the potential treatment of osteoarthritis.
T63155 MMP-9-IN-3
MMP-9-IN-3 is an MMP-9 inhibitor (IC50: 5.56 nM) that forms hydrogen bonds with MMP-9. MMP-9-IN-3 inhibits AKT activity (IC50: 2.11 nM). mmp-9-IN-3 is cytotoxic and induces apoptosis. mmp-9-IN-3 can be used to study canc...
T63994 MMP-9-IN-4
MMP-9-IN-4 is an inhibitor of MMP-9 and interacts with MMP-9 to form H-π with an IC50 value of 7.46 nM. MMP-9-IN-4 also inhibits AKT activity with an IC50 value of 8.82 nM. MMP-9-IN-4 induces apoptosis, shows cytotoxicit...
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