ABX-MA1 is a humanized IgG2 monoclonal antibody inhibitor targeting MCAM/MUC18. It significantly reduces homotypic aggregation and heterotypic adhesion with HUVEC, as well as the formation of experimental lung metastasis. In A375SM/WM2664 xenograft mouse models, ABX-MA1 effectively suppresses tumor growth, angiogenesis, and MMP-2 expression, indicating potential for melanoma research.
ABX-MA1
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Catalog No. T9901A-1757
ABX-MA1 is a humanized IgG2 monoclonal antibody inhibitor targeting MCAM/MUC18. It significantly reduces homotypic aggregation and heterotypic adhesion with HUVEC, as well as the formation of experimental lung metastasis. In A375SM/WM2664 xenograft mouse models, ABX-MA1 effectively suppresses tumor growth, angiogenesis, and MMP-2 expression, indicating potential for melanoma research.
ABX-MA1
Cas No. 561063-60-3
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1 mg
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For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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ABX-MA1 is a humanized IgG2 monoclonal antibody inhibitor targeting MCAM/MUC18. It significantly reduces homotypic aggregation and heterotypic adhesion with HUVEC, as well as the formation of experimental lung metastasis. In A375SM/WM2664 xenograft mouse models, ABX-MA1 effectively suppresses tumor growth, angiogenesis, and MMP-2 expression, indicating potential for melanoma research.
Chemical Properties
Cas No.
561063-60-3
Storage & Solubility Information
Storage
Store at low temperature | Store at -20°C | Shipping with blue ice/Shipping at ambient temperature.
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