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Results for "

antidepressant

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    455
    TargetMol | Inhibitors_Agonists
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    TargetMol | Compound_Libraries
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    TargetMol | Inhibitors_Agonists
bimu 8
T21946134296-40-5In house
BIMU 8 is a selective agonist of 5-HT4 with EC50s of 18 nM, 77 nM, and 540 nM for wild-type 5HT4 receptor, T3.36A, and W6.48A mutant 5-HT4.
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Methylene Blue trihydrate
Methylthionine chloride, Methylene Blue, Basic blue 9
T00067220-79-3
Methylene Blue trihydrate (Basic blue 9) is a compound consisting of dark green crystals or crystalline powder, having a bronze-like luster. Solutions in water or alcohol have a deep blue color. Methylene Blue trihydrate is used as a bacteriologic stain and as an indicator. It inhibits soluble guanylyl cyclase and has been used to treat cyanide poisoning and to lower levels of methemoglobin. It also inhibits tau filament formation (IC50: 1.9μM).
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Mirtazapine
Org3770, 6-Azamianserin
T013785650-52-8
Mirtazapine (6-Azamianserin) is a tetracyclic antidepressant with a somewhat unique mechanism of action. Mirtazapine therapy can be associated with transient asymptomatic elevations in serum aminotransferase levels and has been linked to rare instances of clinically apparent acute liver injury.
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Agomelatine
Valdoxan, Thymanax, S-20098
T1445138112-76-2
Agomelatine (Valdoxan) is structurally closely related to melatonin. Agomelatine is a potent agonist at melatonin receptors and an antagonist at serotonin-2C (5-HT2C) receptors, tested in an animal model of depression.
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Quetiapine hemifumarate
Quetiapine Fumarate, ICI-204636
T6241111974-72-2
Quetiapine hemifumarate (ICI-204636), an atypical antipsychotic, is used in the treatment of bipolar I mania, schizophrenia, bipolar II depression, bipolar I depression.
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TargetMol | Inhibitor Sale
(E)-3,4,5-Trimethoxycinnamic acid
O-Methylsinapic acid, 3,4,5-Trimethoxy-trans-cinnamic acid, 3,4,5-Trimethoxyphenylacrylic acid
TN286520329-98-0
(E)-3,4,5-Trimethoxycinnamic acid (O-Methylsinapic acid) is a natural compound derived from the roots and rhizomes of Notopterygium incisum.
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Escitalopram
Seroplex, S-(+)-Citalopram, (S)-Citalopram
T0185128196-01-0
Escitalopram (Seroplex) is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate this condition.
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1-2 weeks
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Quetiapine
Quetiapin, ICI204636
T0162111974-69-7
Quetiapine (ICI204636) is used for the therapy of schizophrenia, and for the treatment of acute manic episodes associated with bipolar I disorder. The mechanism of quetiapine' action is thought by mediated through antagonist activity at serotonin and dopamine receptors. Specifically, the D1 and D2 dopamine, the α1 adrenoreceptor and α2 adrenoreceptor, and 5-HT1A and 5-HT2 serotonin receptor subtypes are antagonized. Quetiapine also can inhibit the histamine H1 receptor.
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Gentisein
NSC-329491, NSC329491, NSC 329491
T19931529-49-7
Gentisein (NSC-329491), a primary metabolite of Mangiferin, exhibits significant inhibition of serotonin uptake, demonstrating potency with an IC50 value of 4.7 µM[1][2].
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6-8 weeks
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Bifemelane hydrochloride
T2260562232-46-6
Bifemelane hydrochloride is a MAO inhibitor
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S-Adenosyl-L-methionine
SAMe, S-Adenosyl methionine, AdoMet, Ademetionine
T747529908-03-0
S-Adenosyl-L-methionine (Ademetionine) is an intermediate metabolite of methionine,for treatment of primary biliary cirrhosis and major depressive disorder.
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Inquiry
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GSK163090
TQ0311844903-58-8
GSK163090 is a specific and orally active 5-HT1A B D receptor antagonist (pKis: 9.4 8.5 9.7, and 6.3 6.7 for 5-HT1A B D, and dopamine D2 D3).
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Antidepressant agent 5
T785561071049-42-7
Antidepressant agent 5 is a 7-substituted tetrahydroisoquinoline derivative with antidepressant activity.Antidepressant agent 5 acts similarly to magnoflorine in the study of depression and can be used for the prevention and treatment of depressive disorders.
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Antidepressant agent 1
T1033267411-41-0
Antidepressant agent 1, a pyrazidole-halogeno-derivative, exhibits antidepressant effects and can also be used to increase body temperature.
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7-10 days
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Antidepressant agent 8
T2052323066104-04-6
Antidepressant agent 8 (Compound 1f) acts as a selective antagonist for the NMDA receptor GluN1 2A (NMDA receptorGluN1 2A), with an IC50 of 2.94 μmol L. In a hydrocortisone-induced zebrafish depression model, it demonstrates antidepressant-like effects and shows good blood-brain barrier penetration.
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10-14 weeks
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Analgesic/antidepressant agent-1
T205604
Analgesic antidepressant agent-1 (Compound k1) is an orally active N-acetylamino chloro ketone derivative capable of crossing the blood-brain barrier. It exhibits high affinity for NMDA receptors and demonstrates analgesic, anti-inflammatory, and antidepressant properties, with low psychotomimetic activity.
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Antidepressant agent 9
T205640143899-90-5
Antidepressant agent 9 (Compound 24) is an orally active inhibitor of NMDAR and SERT, with IC50 values of 3.50 μM and 1044 nM, respectively. It exhibits good metabolic stability and plasma exposure, and demonstrates antidepressant-like effects in the forced swim test in mice.
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10-14 weeks
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Antidepressant agent 2
T62495
Antidepressant agent 2 showed significant antidepressant effects with a MED value of 0.1 mg kg.
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10-14 weeks
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Antidepressant agent 3
T75002
Antidepressant agent 3, an orally active compound, showcases multifaceted pharmacological properties including antidepressant, anxiolytic, performance-enhancing, and nootropic activities [1].
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Antidepressant agent 4
T75003
Antidepressant agent 4, an orally active compound, demonstrates efficacy as an antidepressant with additional anxiolytic, performance-enhancing, and nootropic activities [1].
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Tabernanthalog
TBG
T602212483829-58-7
Tabernanthalog (TBG) is a 5-HT2A agonist. In rodents,Tabernanthalog has been found to promote structural neuroplasticity, reduce alcohol-seeking and heroin-seeking behavior, and produce antidepressant effects.
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TargetMol | Inhibitor Hot
TAK-137
TAK137
T708801358749-55-9In house
TAK-137 is an AMPA receptor enhancer with antidepressant effects. TAK-137 has the ability to improve cognition and could be used to study schizophrenia.
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6-8 weeks
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TargetMol | Inhibitor Hot
EGLU
(2S)-α-Ethylglutamic acid, (2S)-α-EGLU
T11165170984-72-2In house
EGLU ((2S)-α-Ethylglutamic acid) is a competitive mGluR-2 receptor antagonist with antidepressant activity and anti-injury effects, which can be used in the study of arthritis.
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7-10 days
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EMDT
T11183263744-72-5In house
EMDT oxalate, a selective 5-HT6 agonist, exhibits antidepressant effects.
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6-8 weeks
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