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Search Result

Search Results for "antidepressant"

Libraries

Antidepressant Compound Library
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Compounds

Cat No. Product Name
T75003 Antidepressant agent 4
Antidepressant agent 4 是一种具有口服活性的抗抑郁剂。Antidepressant agent 4 具有抗抑郁，抗焦虑，性能增强和促智活性。
T75002 Antidepressant agent 3
Antidepressant agent 3 是一种具有口服活性的抗抑郁剂。Antidepressant agent 3 具有抗抑郁，抗焦虑，性能增强和促智活性。
T62495 Antidepressant agent 2
Antidepressant agent 2 表现出明显的抗抑郁作用，其 MED 值为 0.1 mg/kg。
T10332 Antidepressant agent 1 Others
Antidepressant agent 1 is a pyrazidole-halogeno-derivative with antidepressant effects. It also can be used to increase ...
T3886 Rosavin 络塞维,Rosavidin P450
Rosavin 是从R. rosea 中获得的，在小鼠模型中表现出抗抑郁、适应原性和抗焦虑样作用。
T15090 Decoglurant RO4995819 GluR
Decoglurant 是 mGluR2和 mGluR3的负变构调制器，有抗抑郁作用。
T9787 Suvn-911 AChR
SUVN-911 是高选择性的，大脑通透性的和口服有效的神经元烟碱乙酰胆碱 α4β2 受体拮抗剂，Ki 为 1.5 nM。SUVN-911显示出抗抑郁作用。
T13318 VU0650786 GluR
VU0650786 是能透过中枢神经系统的，选择性谷氨酸受体亚型 3 的一种负变构调节剂，IC50值为 392 nM，有抗抑郁和抗焦虑活性。
T39341 FCPR03 PDE
FCPR03 是一种特异性磷酸二酯酶 4 (PDE4) 抑制剂，对 PDE4B1、PDE4D7 和 PDE4 催化结构域的 IC50 分别为 31 nM、47 nM 和 60 nM。 FCPR03 具有神经保护、抗炎和抗抑郁样作用。
T16421 P-MPPI hydrochloride 5-HT Receptor
p-MPPI hydrochloride 是一种选择性的，具有高亲和力的5-HT1A 受体拮抗剂，能穿过血脑屏障，具有抗抑郁和抗焦虑样作用。
T15795 Luzindole N-0774,N-乙酰-2-苄基色胺 MT Receptor , Melatonin Receptor
Luzindole 是一种选择性褪黑素受体拮抗剂，可抑制实验性自身免疫性脑脊髓炎，有抗抑郁样活性。它优先靶向 MT2 (Mel1b)，对于人 MT2 和 MT1 的 Ki 值分别为 10.2 和 158 nM。
T22051 BU 224 hydrochloride Imidazoline Receptor
BU 224 hydrochloride 是一种选择性的咪唑啉 I(2) 结合位点配体，具有镇痛和抗抑郁样活性。
T0185 Escitalopram Seroplex,S-(+)-Citalopram,(S)-Citalopram,依他普仑,艾司西酞普兰 Serotonin Transporter , Adrenergic Receptor , Dopamine Receptor , Histamine Receptor , 5-HT Receptor , Norepinephrine , AChR
Escitalopram 是一种外消旋 Citalopram 的 S-对映体，是一种选择性 5-羟色胺再摄取抑制剂，Ki=0.89 nM，比 R(-)-enantiomer 结合亲和力高 30 倍。它对多巴胺转运体和去甲肾上腺素转运体均有选...
T4274 Melitracen hydrochloride 盐酸美利曲辛,盐酸美力他欣,Melixeran,Thymeol hydrochloride 5-HT Receptor , Dopamine Receptor
Melitracen hydrochloride 是一种可口服的双相抗抑郁药和抗焦虑药。它可以通过突触前膜抑制去甲肾上腺素和5-羟色胺(5-HT)的吸收，从而诱导突触空间中单胺递质的增加。
T26375 (S)-Amisulpride (S)-氨磺必利,Esamisulpride,SEP-4199 Dopamine Receptor , 5-HT Receptor
(S)-Amisulpride 是一种有效的多巴胺D2/D3受体拮抗剂，具有抗精神和抗抑郁作用。它是5-HT7受体的拮抗剂，KI 值为 900 nM。
T0137 Mirtazapine 米氮平,6-Azamianserin,Org3770 Histamine Receptor , Adrenergic Receptor , 5-HT Receptor , Opioid Receptor , Dopamine Receptor
Mirtazapine 是一种有效的具有口服活性的去甲肾上腺素能和特异性血清素能抗抑郁剂 (NaSSA)。它也是一种5-HT2、5-HT3、组胺 H1 受体和 α2-肾上腺素受体拮抗剂，pKi 值分别为 8.05、8.1、9.3 和 6.9...
T0255 Clomipramine hydrochloride Anafranil,Clomipramine HCl,盐酸氯米帕明 GST , Dopamine Receptor , 5-HT Receptor , Norepinephrine , Serotonin Transporter
Clomipramine hydrochloride 是一种5-羟色胺转运体(Ki:0.14 nM)、去甲肾上腺素转运体(Ki:54 nM)和多巴胺转运体(Ki:3 nM)阻断剂。
T3275 Nefazodone hydrochloride 萘法唑酮盐酸盐,BMY-13754-1,BMY-13754,Dutonin,Serzone,MJ-13754-1 Adrenergic Receptor , 5-HT Receptor
Nefazodone hydrochloride 是一种强效和选择性的5HT2A 拮抗剂，Ki 为5.8 nM，对 5-HT 和去甲肾上腺素摄取具有中度抑制作用，IC50分别为 290 和 300 nM。它是一种苯哌嗪类抗抑郁药，具有微弱的...
T21013 Clomipramine Anafranil (free base),Clomicalm,Clomipramina,Chlorimipramine,Anafranil,氯米帕明 5-HT Receptor
Clomipramine 是一种三环类抗抑郁药，能够有效阻断 5-HT 再摄取 (IC50:1.5 nM) ，可用于研究强迫症 (OCD) 及抑郁症。
T4297 Flibanserin Girosa,BIMT-17BS,BIMT-17,氟立班丝氨 5-HT Receptor , Dopamine Receptor
Flibanserin 一种具有口服活性的 5-HT1A 受体激动剂和 5-HT2A 受体拮抗剂，Ki 值分别为 1 和 49 nM。它与多巴胺 D4 受体结合，Ki 值在 4 到 24 nM 之间。它是一种血清素能抗抑郁药，用于治疗性欲减...
Antidepressant agent 4
T75003
synonym:
Target:
Antidepressant agent 3
T75002
synonym:
Target:
Antidepressant agent 2
T62495
synonym:
Target:
Antidepressant agent 1
T10332
synonym:
Target:
Rosavin
T3886
synonym: 络塞维,Rosavidin
Target:
Decoglurant
T15090
synonym: RO4995819
Target:
suvn-911
T9787
synonym:
Target:
VU0650786
T13318
synonym:
Target:
FCPR03
T39341
synonym:
Target:
p-MPPI hydrochloride
T16421
synonym:
Target:
Luzindole
T15795
synonym: N-0774,N-乙酰-2-苄基色胺
Target:
BU 224 hydrochloride
T22051
synonym:
Target:
Escitalopram
T0185
synonym: Seroplex,S-(+)-Citalopram,(S)-Citalopram,依他普仑,艾司西酞普兰
Target:
Melitracen hydrochloride
T4274
synonym: 盐酸美利曲辛,盐酸美力他欣,Melixeran,Thymeol hydrochloride
Target:
(S)-Amisulpride
T26375
synonym: (S)-氨磺必利,Esamisulpride,SEP-4199
Target:
Mirtazapine
T0137
synonym: 米氮平,6-Azamianserin,Org3770
Target:
Clomipramine hydrochloride
T0255
synonym: Anafranil,Clomipramine HCl,盐酸氯米帕明
Target:
Nefazodone hydrochloride
T3275
synonym: 萘法唑酮盐酸盐,BMY-13754-1,BMY-13754,Dutonin,Serzone,MJ-13754-1
Target:
Clomipramine
T21013
synonym: Anafranil (free base),Clomicalm,Clomipramina,Chlorimipramine,Anafranil,氯米帕明
Target:
Flibanserin
T4297
synonym: Girosa,BIMT-17BS,BIMT-17,氟立班丝氨
Target:
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