Dehydrogenase

A dehydrogenase (also called DH or DHase in the literature) is an enzyme belonging to the group of oxidoreductases that oxidizes a substrate by reducing an electron acceptor, usually NAD+/NADP+ or a flavin coenzyme such as FAD or FMN. They also catalyze the reverse reaction, for instance alcohol dehydrogenase not only oxidizes ethanol to acetaldehyde in animals but also produces ethanol from acetaldehyde in yeast.

Cat. No.	Product name	CAS No.	Purity
T11238	Etamicastat	760173-05-5	98%
T11238	Etamicastat can be used in the research of cardiovascular diseases. Etamicastat (BIA 5-453) is a potent and reversible dopamine-β-hydroxylase (DBH) inhibitor wit...
T12614L	BMS-816336	1009583-20-3	98%
T12614L	BMS-816336 is a novel, orally bioavailable inhibitor, and potent against human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme with an IC50 of 3.0 nM[1...
T11611	IDH1 Inhibitor 2	2244895-42-7	98%
T11611	IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor via direct covalent modification of His315 (IC50: 110 nM).
T13453	CGRP antagonist 1	1123757-49-2	98%
T13453	CGRP antagonist 1 is a highly potent antagonist of CGRP receptor(Ki and IC50 of 35 and 57 nM, respectively).
T14780	BRD9185	2057420-29-6	98%
T14780	BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.
T12663	(Rac)-BMS-816336	T12663	98%
T12663	(Rac)-BMS-816336 (Compound 6n) is a racemate of BMS-816336. (Rac)-BMS-816336 is a potent inhibitor of human and mouse 11β-hydroxysteroid dehydrogenase type 1 (11...
T14383	AZD8329	1048668-70-7	98%
T14383	AZD8329 is a potent inhibitor of 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1)(IC50 of 9 nM for human 11β-HSD1), and displays excellent selectivity versus 1...
T2637	ADH-1	229971-81-7	98%
T2637	Exherin (ADH-1) is an N-cadherin antagonist, inhibits N-cadherin mediated cell adhesion with potential antineoplastic and antiangiogenic activities.
TN1298	6''-O-Acetylglycitin	134859-96-4	98%
TN1298	6''-O-Acetylglycitin is a potential nutriceutical, it is also a potent LDH inhibitor.
T15362	FX-11	213971-34-7	98%
T15362	FX-11 is a potent inhibitor of lactate dehydrogenase A (LDHA) (IC50: 23.3 μM for HeLa cell and Ki: 8 μM).
T11238L	Etamicastat hydrochloride	677773-32-9	98%
T11238L	Etamicastat can be used in the research of cardiovascular diseases.Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a potent and reversible dopamine-β-hydr...
T13054	T-3764518	1809151-56-1	98%
T13054	T-3764518 is a novel and potent inhibitor of stearoyl coenzyme A desaturase (SCD)(IC50 of 4.7 nM).
T10160	11β-HSD1-IN-1	1203956-47-1	98%
T10160	11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.
T14388	AZD 4017	1024033-43-9	98%
T14388	AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM).
T12196	NCT-505	2231079-74-4	98%
T12196	NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1)(IC50 of 7 nM).
T15551	IDH889	1429179-07-6	98%
T15551	IDH889 is a brain penetrant, an allosteric and mutant specific IDH1 inhibitor. IDH889 has effective selectivity for IDH1 R132* mutations (IC50s: 0.02 μM, 0.072 μ...
T9494	3-(IMIDAZOL-4-YL)PROPIONIC ACID	1074-59-5	98%
T9494	3-(IMIDAZOL-4-YL)PROPIONIC ACID is a product of histidine metabolism and may involve oxidation or transamination. 3-(IMIDAZOL-4-YL)PROPIONIC ACID is potent inhib...
T60149	11β-HSD1-IN-11	859721-81-6	98%
T60149	11β-HSD1-IN-11 is a competitive 11β-HSD1 inhibitor with IC50s of 0.34 μM and 0.13 μM against rat and human 11β-HSD1, respectively.
T16510	PF-915275	857290-04-1	98%
T16510	The dose-dependent effect of PF-915275 on the conversion of cortisone to cortisol in primary human and monkey hepatocytes (EC50: 20 and 100 nM, respectively). PF...
T40686	Tiazofurin	60084-10-8	98%
T40686	Tiazofurin is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotid...