Dehydrogenase

A dehydrogenase (also called DH or DHase in the literature) is an enzyme belonging to the group of oxidoreductases that oxidizes a substrate by reducing an electron acceptor, usually NAD+/NADP+ or a flavin coenzyme such as FAD or FMN. They also catalyze the reverse reaction, for instance alcohol dehydrogenase not only oxidizes ethanol to acetaldehyde in animals but also produces ethanol from acetaldehyde in yeast.

Cat. No.	Product name	CAS No.	Purity
T13453	CGRP antagonist 1	1123757-49-2	98%
T13453	CGRP antagonist 1 is a highly potent antagonist of CGRP receptor(Ki and IC50 of 35 and 57 nM, respectively).
TN1298	6''-O-Acetylglycitin	134859-96-4	98%
TN1298	6''-O-Acetylglycitin is a potential nutriceutical, it is also a potent LDH inhibitor.
T2637	ADH-1	229971-81-7	98%
T2637	Exherin (ADH-1) is an N-cadherin antagonist, inhibits N-cadherin mediated cell adhesion with potential antineoplastic and antiangiogenic activities.
T13054	T-3764518	1809151-56-1	98%
T13054	T-3764518 is a novel and potent inhibitor of stearoyl coenzyme A desaturase (SCD)(IC50 of 4.7 nM).
T14383	AZD8329	1048668-70-7	98%
T14383	AZD8329 is a selectable and potent inhibitor of human recombinant 11β-HSD1 and isolated human adipocyte 11ß-HSD1 and is an inhibitor of rat 11β-HSD1 (IC50 - 89nM...
T11238	Etamicastat	760173-05-5	98%
T11238	Etamicastat can be used in the research of cardiovascular diseases. Etamicastat (BIA 5-453) is a potent and reversible dopamine-β-hydroxylase (DBH) inhibitor wit...
T12663	(Rac)-BMS-816336	T12663	98%
T12663	(Rac)-BMS-816336 (Compound 6n) is a racemate of BMS-816336. (Rac)-BMS-816336 is a potent human and mouse 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzym...
T11611	IDH1 Inhibitor 2	2244895-42-7	98%
T11611	IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor via direct covalent modification of His315 (IC50: 110 nM).
T12614L	BMS-816336	1009583-20-3	98%
T12614L	BMS-816336 is a novel, orally bioavailable inhibitor, and potent against human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme with an IC50 of 3.0 nM[1...
T14780	BRD9185	2057420-29-6	98%
T14780	BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.
T10148	4-Hydroxynonenal	75899-68-2	98%
T10148	4-Hydroxynonenal (4-HNE) is an oxidative/nitrosative stress biomarker. It is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2).
T14388	AZD 4017	1024033-43-9	98%
T14388	AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM).
T15551	IDH889	1429179-07-6	98%
T15551	IDH889 is a brain penetrant, an allosteric and mutant specific IDH1 inhibitor. IDH889 has effective selectivity for IDH1 R132* mutations (IC50s: 0.02 μM, 0.072 μ...
T9974	WAY-324168	663214-48-0	98%
T9974	WAY-324168 is a compound with antiproliferative activity.
T37190	L-Allylglycine	16338-48-0	98%
T37190	L-Allylglycine is an amino acid derivative that reduces glutamate decarboxylase (GAD) activity by 60% when administered at a dose of 39.8 μmol/g per hour ex vivo...
T40686	Tiazofurin	60084-10-8	98%
T40686	Tiazofurin is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotid...
T77606	WAY-311610	314051-55-3	98%
T77606	WAY-311610 is an 11β-hydroxysteroid dehydrogenase HSD11B1 inhibitor that inhibits the 11β-HSD1 enzyme with an IC = 0.34 μM.It can be used to study neuropathic pa...
T10146	4-Hydroxyderricin	55912-03-3	98%
T10146	4-Hydroxyderricin, a potent and selective MAO-B inhibitor (IC50: 3.43 μM), is the main active ingredient of Angelica sinensis, which mildly inhibits dopamine β-h...
T77579	JC2-11	937820-89-8	98%
T77579	JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical ...
T12196	NCT-505	2231079-74-4	98%
T12196	NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1)(IC50 of 7 nM).