T11238 |
Etamicastat
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760173-05-5
|
98%
|
|
Etamicastat can be used in the research of cardiovascular diseases. Etamicastat (BIA 5-453) is a potent and reversible dopamine-β-hydroxylase (DBH) inhibitor wit...
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T12614L |
BMS-816336
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1009583-20-3
|
98%
|
|
BMS-816336 is a novel, orally bioavailable inhibitor, and potent against human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme with an IC50 of 3.0 nM[1...
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T11611 |
IDH1 Inhibitor 2
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2244895-42-7
|
98%
|
|
IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor via direct covalent modification of His315 (IC50: 110 nM).
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T13453 |
CGRP antagonist 1
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1123757-49-2
|
98%
|
|
CGRP antagonist 1 is a highly potent antagonist of CGRP receptor(Ki and IC50 of 35 and 57 nM, respectively).
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T14780 |
BRD9185
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2057420-29-6
|
98%
|
|
BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.
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T12663 |
(Rac)-BMS-816336
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T12663
|
98%
|
|
(Rac)-BMS-816336 (Compound 6n) is a racemate of BMS-816336. (Rac)-BMS-816336 is a potent inhibitor of human and mouse 11β-hydroxysteroid dehydrogenase type 1 (11...
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T14383 |
AZD8329
|
1048668-70-7
|
98%
|
|
AZD8329 is a potent inhibitor of 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1)(IC50 of 9 nM for human 11β-HSD1), and displays excellent selectivity versus 1...
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T2637 |
ADH-1
|
229971-81-7
|
98%
|
|
Exherin (ADH-1) is an N-cadherin antagonist, inhibits N-cadherin mediated cell adhesion with potential antineoplastic and antiangiogenic activities.
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TN1298 |
6''-O-Acetylglycitin
|
134859-96-4
|
98%
|
|
6''-O-Acetylglycitin is a potential nutriceutical, it is also a potent LDH inhibitor.
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T15362 |
FX-11
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213971-34-7
|
98%
|
|
FX-11 is a potent inhibitor of lactate dehydrogenase A (LDHA) (IC50: 23.3 μM for HeLa cell and Ki: 8 μM).
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T11238L |
Etamicastat hydrochloride
|
677773-32-9
|
98%
|
|
Etamicastat can be used in the research of cardiovascular diseases.Etamicastat hydrochloride (BIA 5-453 hydrochloride) is a potent and reversible dopamine-β-hydr...
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T13054 |
T-3764518
|
1809151-56-1
|
98%
|
|
T-3764518 is a novel and potent inhibitor of stearoyl coenzyme A desaturase (SCD)(IC50 of 4.7 nM).
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T10160 |
11β-HSD1-IN-1
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1203956-47-1
|
98%
|
|
11β-HSD1-IN-1 is an inhibitor of 11β-hydroxydehydrogenase 1 (11β-HSD1, IC50: 52 nM), and used for the treatment of pain.
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T14388 |
AZD 4017
|
1024033-43-9
|
98%
|
|
AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM).
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T12196 |
NCT-505
|
2231079-74-4
|
98%
|
|
NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1)(IC50 of 7 nM).
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T15551 |
IDH889
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1429179-07-6
|
98%
|
|
IDH889 is a brain penetrant, an allosteric and mutant specific IDH1 inhibitor. IDH889 has effective selectivity for IDH1 R132* mutations (IC50s: 0.02 μM, 0.072 μ...
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T9494 |
3-(IMIDAZOL-4-YL)PROPIONIC ACID
|
1074-59-5
|
98%
|
|
3-(IMIDAZOL-4-YL)PROPIONIC ACID is a product of histidine metabolism and may involve oxidation or transamination. 3-(IMIDAZOL-4-YL)PROPIONIC ACID is potent inhib...
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T60149 |
11β-HSD1-IN-11
|
859721-81-6
|
98%
|
|
11β-HSD1-IN-11 is a competitive 11β-HSD1 inhibitor with IC50s of 0.34 μM and 0.13 μM against rat and human 11β-HSD1, respectively.
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T16510 |
PF-915275
|
857290-04-1
|
98%
|
|
The dose-dependent effect of PF-915275 on the conversion of cortisone to cortisol in primary human and monkey hepatocytes (EC50: 20 and 100 nM, respectively). PF...
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T40686 |
Tiazofurin
|
60084-10-8
|
98%
|
|
Tiazofurin is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotid...
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