T13453 |
CGRP antagonist 1
|
1123757-49-2
|
98%
|
|
CGRP antagonist 1 is a highly potent antagonist of CGRP receptor(Ki and IC50 of 35 and 57 nM, respectively).
|
TN1298 |
6''-O-Acetylglycitin
|
134859-96-4
|
98%
|
|
6''-O-Acetylglycitin is a potential nutriceutical, it is also a potent LDH inhibitor.
|
T2637 |
ADH-1
|
229971-81-7
|
98%
|
|
Exherin (ADH-1) is an N-cadherin antagonist, inhibits N-cadherin mediated cell adhesion with potential antineoplastic and antiangiogenic activities.
|
T13054 |
T-3764518
|
1809151-56-1
|
98%
|
|
T-3764518 is a novel and potent inhibitor of stearoyl coenzyme A desaturase (SCD)(IC50 of 4.7 nM).
|
T14383 |
AZD8329
|
1048668-70-7
|
98%
|
|
AZD8329 is a selectable and potent inhibitor of human recombinant 11β-HSD1 and isolated human adipocyte 11ß-HSD1 and is an inhibitor of rat 11β-HSD1 (IC50 - 89nM...
|
T11238 |
Etamicastat
|
760173-05-5
|
98%
|
|
Etamicastat can be used in the research of cardiovascular diseases. Etamicastat (BIA 5-453) is a potent and reversible dopamine-β-hydroxylase (DBH) inhibitor wit...
|
T12663 |
(Rac)-BMS-816336
|
T12663
|
98%
|
|
(Rac)-BMS-816336 (Compound 6n) is a racemate of BMS-816336. (Rac)-BMS-816336 is a potent human and mouse 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzym...
|
T11611 |
IDH1 Inhibitor 2
|
2244895-42-7
|
98%
|
|
IDH1 Inhibitor 2 (compound 13) is a potent IDH1 inhibitor via direct covalent modification of His315 (IC50: 110 nM).
|
T12614L |
BMS-816336
|
1009583-20-3
|
98%
|
|
BMS-816336 is a novel, orally bioavailable inhibitor, and potent against human 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) enzyme with an IC50 of 3.0 nM[1...
|
T14780 |
BRD9185
|
2057420-29-6
|
98%
|
|
BRD9185 is an inhibitor of Dihydroorotate dehydrogenase (DHODH) with an EC50 of 16 nM against multidrug-resistant blood-stage parasites in vitro.
|
T10148 |
4-Hydroxynonenal
|
75899-68-2
|
98%
|
|
4-Hydroxynonenal (4-HNE) is an oxidative/nitrosative stress biomarker. It is a substrate and an inhibitor of acetaldehyde dehydrogenase 2 (ALDH2).
|
T14388 |
AZD 4017
|
1024033-43-9
|
98%
|
|
AZD 4017 is an inhibitor of 11β-Hydroxysteroid Dehydrogenase Type 1(11β-HSD1) (IC50: 7 nM).
|
T15551 |
IDH889
|
1429179-07-6
|
98%
|
|
IDH889 is a brain penetrant, an allosteric and mutant specific IDH1 inhibitor. IDH889 has effective selectivity for IDH1 R132* mutations (IC50s: 0.02 μM, 0.072 μ...
|
T9974 |
WAY-324168
|
663214-48-0
|
98%
|
|
WAY-324168 is a compound with antiproliferative activity.
|
T37190 |
L-Allylglycine
|
16338-48-0
|
98%
|
|
L-Allylglycine is an amino acid derivative that reduces glutamate decarboxylase (GAD) activity by 60% when administered at a dose of 39.8 μmol/g per hour ex vivo...
|
T40686 |
Tiazofurin
|
60084-10-8
|
98%
|
|
Tiazofurin is a synthetic nucleoside analogue with antineoplastic activity. Tiazofurin is anabolized intracellularly to tiazole-4-carboxamide adenine dinucleotid...
|
T77606 |
WAY-311610
|
314051-55-3
|
98%
|
|
WAY-311610 is an 11β-hydroxysteroid dehydrogenase HSD11B1 inhibitor that inhibits the 11β-HSD1 enzyme with an IC = 0.34 μM.It can be used to study neuropathic pa...
|
T10146 |
4-Hydroxyderricin
|
55912-03-3
|
98%
|
|
4-Hydroxyderricin, a potent and selective MAO-B inhibitor (IC50: 3.43 μM), is the main active ingredient of Angelica sinensis, which mildly inhibits dopamine β-h...
|
T77579 |
JC2-11
|
937820-89-8
|
98%
|
|
JC2-11 is an inhibitory compound for inflammation.JC2-11 inhibits the recruitment domain-containing proteins NLRC 4, atypical in melanoma 2 (AIM 2) and atypical ...
|
T12196 |
NCT-505
|
2231079-74-4
|
98%
|
|
NCT-505 is a potent and selective inhibitor of aldehyde dehydrogenase (ALDH1A1)(IC50 of 7 nM).
|