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Erythropoietin‑producing hepatocellular carcinoma cell surface type‑A receptor 3 (EPHA3) has been found to promote the proliferation and survival of prostate cancer (PCa) cell lines and prostate tumor development in nude mice. The interaction of AR and SP1 contributes to regulate EPHA3 expression, and the SP1 binding sites (‑295~‑261) in the EPHA3 core promoter region is crucial to the regulation of EPHA3 expression in response to androgen hormone stimuli.

Expression system: HEK293 Cells
Length: 1-541, Partial
Activity: ELISA

EphA3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60.3 kDa and the accession number is A0A140VJJ0.

Expression system: HEK293 Cells
Length: 1-541, Partial
Activity: ELISA

EphA3 Protein, Mouse, Recombinant (aa 569-984, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 74.3 kDa and the accession number is EDK98238.1.

EphA3 Protein, Mouse, Recombinant (aa 569-984) is expressed in Baculovirus insect cells. The predicted molecular weight is 46.6 kDa and the accession number is EDK98238.1.

Expression system: HEK293 Cells
Length: 20-497, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-223, Full Length
Activity: Not Tested

Expression system: HEK293 Cells
Length: 1-441, Full Length of Isoform Tau-F
Activity: ELISA

Expression system: HEK293 Cells
Length: 1-260, Full Length
Activity: Enzyme activity

Expression system: HEK293 Cells
Length: 1-340, Partial
Activity: Not Tested

SLC39A6 Protein, Rat, Recombinant (HEK293, His) is expressed in in vitro E. coli expression system. The accession number is Q4V887.

Myocilin Protein, Mouse, Recombinant (HEK293, His & Myc) is expressed in Mammalian cell. The accession number is O70624.

GAPDH Protein, Human, Recombinant (HEK293, His) is expressed in Mammalian cell. The accession number is P04406.

NPR2 Protein, Human, Recombinant (HEK293, His) is expressed in Mammalian cell. The accession number is P20594.

Expression system: HEK293 Cells
Length: 18-740, Extracellular Domain
Activity: Not Tested

Cerberus 1 is a secreted glycoprotein that forms disulfide-linked homodimers. It is a cytokine member of the DAN domain family of BMP antagonists that includes DAN (DAND1), Gremlin Drm (DAND2), PRDC (Protein Related to Dan and Cerberus, DAND3), and COCO Dante (DAND5). DAN family members contain a cysteine knot domain that is homologous to that found in other TGF-beta superfamily ligands. At the onset of gastrulation, Cerberus 1 is transiently expressed in anterior endodermal structures in response to Nodal and Shh. Cerberus 1 binds BMP-4 and Nodal and inhibits their activities. The inhibitory functions of Cerberus favor mesodermal development in the anterior region of the gastrula and suppresses posterior mesodermal differentiation. In chick and Xenopus, Cerberus 1 also regulates, but is not required for embryonic left-right polarization, neurulation, and head and heart induction.

SCF C-kit ligand is the ligand of the tyrosine-kinase receptor encoded by the KIT locus. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. KITLG SCF binding can activate several signaling pathways. Promotes phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and subsequent activation of the kinase AKT1. In phase I II clinical studies administration of the combination of SCF and G-CSF resulted in a two- to threefold increase in cells that express the CD34 antigen compared with G-CSF alone.

Small ubiquitin-like modifier (SUMO), also known as SUMO homologue and SMT3, is a member of the superfamily of ubiquitin-like polypeptides that become covalently attached to various intracellular target proteins as a way to alter their function, location, and or half-life. Small ubiquitin-like modifiers include SUMO1, SUMO2, SUMO3, and SUMO4. Except for SUMO4, all other SUMOs are ubiquitously expressed, including in the brain. In human, SUMO2 and SUMO3 are two highly homologous proteins, collectively called SUMO2 3. Several studies suggest that SUMO3 are associated with pathogenesis in several neurological diseases, including Alzheimer's disease, Parkinson's disease, and cerebral ischemia stroke.

Expression system: HEK293 Cells
Length: 27-349, Full Length of Mature Protein
Activity: Not Tested

Expression system: HEK293 Cells
Length: 22-182, Extracellular Domain
Activity: ELISA

Amphiregulin Protein, Human, Recombinant (HEK293) is expressed in HEK293 Cells. The accession number is Q5U026.

IFN-beta Protein, Human, Recombinant (HEK293) is expressed in HEK293 Cells. The accession number is P01574.

IL-1RA Protein, Human, Recombinant (HEK293) is expressed in HEK293 Cells. The accession number is P18510.