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Anti-CHK1 Monoclonal Antibody (5B258)
(Synonyms: CHEK1) Copy Product Info
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Synonyms: CHEK1
Catalog No. TMAT-0488 Copy Product Info
🥰Excellent
Anti-CHK1 Monoclonal Antibody (5B258) is a Mouse antibody targeting CHK1. Anti-CHK1 Monoclonal Antibody (5B258) can be used in WB.
Anti-CHK1 Monoclonal Antibody
(5B258)
| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 20 µL | Inquiry | 7-10 days | 7-10 days | |
| 50 µL | Inquiry | 7-10 days | 7-10 days | |
| 100 µL | Inquiry | 7-10 days | 7-10 days |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Stability & Storage
| Description | Anti-CHK1 Monoclonal Antibody (5B258) is a Mouse antibody targeting CHK1. Anti-CHK1 Monoclonal Antibody (5B258) can be used in WB. |
| Synonyms | CHEK1 |
| Ig Type | IgG1 |
| Clone | 5B258 |
| Reactivity | Human,Mouse |
| Application | |
| Recommended Dose | WB: 1/500-1/2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Purified by protein A or protein G |
| Appearance | Liquid |
| Formulation | PBS with 0.05% sodium azide |
| Concentration | 1 mg/ml |
| Research Background | CHK1, also known as CHEK1, it is a kinase that phosphorylates cdc25, an important phosphatase in cell cycle control, particularly for entry into mitosis. Cdc25, when phosphorylated on serine 216 by chk1 becomes bound by an adaptor protein in the cytoplasm. Therefore it is inhibited from removing the inhibiting phosphate from MPF (mitotic/maturation promoting factor) added by Wee1. Consequently, a cell is prevented from entering mitosis. Chk1 can also phosphorylate p53 at Ser20 in vitro. |
| Conjucates | Unconjugated |
| Immunogen | Purified recombinant fragment of CHK1 expressed in E. Coli. |
| Antigen Species | Human |
| Gene Name | CHEK1 |
| Gene ID | |
| Protein Name | Serine/threonine-protein kinase Chk1 |
| Uniprot ID |
| Stability & Storage | Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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