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Results for "

obesity

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    403
    TargetMol | Inhibitors_Agonists
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    5
    TargetMol | Compound_Libraries
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    46
    TargetMol | Peptide_Products
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    TargetMol | Inhibitory_Antibodies
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    TargetMol | Natural_Products
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    TargetMol | Inhibitors_Agonists
GSK1940029
SCD inhibitor 1
T54271150701-66-8In house
GSK1940029 (SCD inhibitor 1) is an inhibitor of stearoyl-CoA desaturase (SCD).
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7-10 days
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β-Aminopropionitrile
BAPN, 3-Aminopropionitrile
T13475151-18-8
β-Aminopropionitrile (3-Aminopropionitrile) is a selective inhibitor of lysyl oxidase.
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β-Nicotinamide mononucleotide
β-NM, NMN
T47211094-61-7
β-nicotinamide mononucleotide (NMN) is a natural nucleotide and a key intermediate in the synthesis of coenzyme I (NAD+). β-nicotinamide mononucleotide is involved in a number of biochemical reactions in the human body, which are related to immunity and metabolism.
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Sucrose
D(+)-Sucrose, D-(+)-Saccharose
T473357-50-1
Sucrose (D-(+)-Saccharose) is a nonreducing disaccharide composed of glucose and fructose linked via their anomeric carbons.
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(-)-Hydroxycitric acid
Garcinia acid
T1159027750-10-3
(-)-Hydroxycitric acid (Garcinia acid) is the principal acid found in the fruit rinds of Garcinia cambogia. It acts as a potent and competitive inhibitor of ATP citrate lyase, suppressing fatty acid synthesis, food intake, lipogenesis, and inducing weight loss.
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TargetMol | Inhibitor Sale
Voacamine
Voacanginine
T2S02713371-85-5
Voacamine (Voacanginine) is an indole alkaloid. Voacamine exhibits potent cannabinoid CB1 receptor antagonistic activity. Voacamine also inhibits P-glycoprotein (P-gp) action in multidrug-resistant tumor cells.Voacanginine may have rhythmic effects.
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3-chloro-5-hydroxybenzoic Acid
T748253984-36-4
3-chloro-5-hydroxy Benzoic Acid (3-chloro-5-hydroxy BA) is an agonist of GPR81 (EC50 : 16 μM)
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3,5,7,3′,4′-Pentamethoxyflavone
Quercetin 3,5,7,3,4-pentamethyl ether
TN21211247-97-8
3,5,7,3′,4′-Pentamethoxyflavone (Quercetin 3,5,7,3,4-pentamethyl ether) is a natural product that induces adipogenesis in 3T3-L1 preadipocytes by regulating transcription factors during the early stages of differentiation.
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beta-Amyrone
β-Amyron
TN3500638-97-1
beta-Amyrone (β-Amyron) has antifungal activity against Chikungunya virus replication with an EC50 of 86 uM. beta-Amyrone has anti-inflammatory activity through inhibiting the expression of COX-2. beta-Amyrone exhibits anti-α-glucosidase inhibitory activity and moderate AChE activity. β-Amyrone can be used in the research of disease like inflammation, infection, and obesity.
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AG-1478
Tyrphostin AG-1478, NSC 693255, AG1478
T2047153436-53-4
AG-1478 (NSC-693255) (Tyrphostin AG-1478) is a selective EGFR inhibitor.
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Anti-obesity agent 1
T204516
Compound 4 (Anti-obesity agent 1) demonstrates potential for enhanced lipolysis, highlighting its anti-obesity characteristics.
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Agrimol B
T4S117355576-66-4
1. Agrimol B is a main active ingredient isolated from Agrimonia pilosa Ledeb.
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CL 316243
T10830138908-40-4In house
CL316243 is a highly potent selective agonist of β3-adrenoceptor, with a EC50 of 3 nM. CL316243 is an effective stimulant of adipocyte lipolysis and increases brown adipose tissue thermogenesis and metabolic rate. CL316243 has the potential for the treatment obesity, diabetes and urge urinary incontinence.
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6-8 weeks
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TargetMol | Inhibitor Hot
KDM4-IN-4
T603542230475-63-3In house
KDM4-IN-4 (compound 47) is a potent inhibitor of histone lysine demethylase 4 (KDM4), with a binding constant of approximately 80 μM for the KDM4A-Tudor domain. It inhibits H3K4Me3 binding to the Tudor domain in cellular contexts with an EC50 value of 105 μM, holding potential for anticancer research applications [1].
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8-10 weeks
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TargetMol | Inhibitor Hot
Liraglutide
Victoza, NN2211, Liraglutidum, Liraglutida
T6876204656-20-2
Liraglutide (Liraglutida) is a synthetic analog of glucagon-like peptide-1 (GLP-1), an agonist of the GLP-1 receptor. Liraglutide can be used to treat type 2 diabetes and chronic obesity.
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TargetMol | Inhibitor Hot
tirzepatide
LY-3298176
TP11112023788-19-2
Tirzepatide (LY-3298176) is a dual agonist of glucose-dependent polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor with neuroprotective activity for the study of diabetes and obesity.
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TargetMol | Inhibitor Hot
Tirzepatide monosodium salt
Tirzepatide sodium salt(2023788-19-2 free base), LY-3298176 sodium salt
TP1111L1
Tirzepatide sodium salt (LY3298176 sodium salt) is a GIP and GLP-1 receptor agonist with neuroprotective activity and can be used to treat obesity.
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TargetMol | Inhibitor Hot
DGAT-1 inhibitor 2
T11016942999-61-3In house
DGAT-1 inhibitor 2 is an effective DGAT-1 inhibitor and anti-obesity drug. DGAT-1 (acyl-CoA: diacylglycerol acyltransferase 1) is one of two known DGAT enzymes that catalyze the final step of triglyceride synthesis. Transgenic mice and pharmacological studies indicate that inhibiting DGAT1 is a promising strategy for treating obesity and type 2 diabetes.
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8-10 weeks
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TargetMol | Inhibitor Sale
L-692429
MK-0751
T11798145455-23-8In house
L-692429 (MK-0751) is a potent nonpeptidyl growth hormone secretagogue (GHS) agonist and benzolactam derivative, known for reversing glucocorticoid-induced inhibition of GH secretion. L-692429 exhibits high affinity for the G protein-coupled receptor and is useful in studying acromegaly and obesity.
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6-8 weeks
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Pradigastat
LCQ908-NXA, LCQ908A, LCQ-908, ANJ908
T11827956136-95-1In house
Pradigastat (LCQ-908) is an orally active, potent and selective diacylglycerol acyltransferase 1 (DGAT1) inhibitor for the treatment of constipation, which may be used in the study of obesity and diabetes.
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4-6 weeks
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Peliglitazar racemate
BMS 426707-01 racemate, (Rac)-Peliglitazar, (Rac)-BMS 426707-01
T12400331744-72-0In house
Peliglitazar racemate(BMS 426707-01 racemate) is the racemate of Peliglitazar.Peliglitazar racemate may be used as a potential antidiabetic and anti-obesity agent.
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6-8 weeks
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(Rac)-WAY-161503
T1333275704-24-4In house
(Rac)-WAY-161503 is a selective and high-affinity agonist of the 5-HT2C receptor [Ki: 4 nM; EC50: 12 nM], exhibiting anti-obesity and antidepressant effects.
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6-8 weeks
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(2R,3S)-Azelaprag
T14390L2049979-31-7In house
(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5-methylpyrimidin-2-yl)butane-2-sulfonamide is an Apelin receptor agonist with an EC50 for Apelin receptors of 0.012 µM.(2R,3S)-N-(4-(2,6-dimethoxyphenyl)-5-(5-methylpyridin-3-yl)-4H-1,2,4-triazol-3-yl)-3-(5- methylpyrimidin-2-yl)butane-2-sulfonamide is used in the treatment of heart failure, atherosclerosis, obesity, diabetes mellitus, amyotrophic lateral sclerosis, coronary artery disease, hypertension, stroke and myocardial infarction.
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10-14 weeks
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KHK-IN-1
KHK-IN-8, Ketohexokinase inhibitor 8
T156601303469-70-6In house
KHK-IN-1 (KHK-IN-8) is a selective and cell membrane permeable inhibitor of ketohexokinase (KHK, IC50=12 nM; F=34%). KHK-IN-1 inhibits F1P production in HepG2 cell lysates with IC50 of 400 nM. KHK-IN-1 has potential for the study of obesity and diabetes.
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