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Search Results for " immunoglobulin "

20

Compounds

Cat No. Product Name Synonyms Targets
T22865 immunoglobulin light chain variable region fragment [Homo sapiens] Others
Immunoglobulin light chain variable region fragment [Homo sapiens] is a fragment (Phe-Thr-Leu-Lys-Ile-Ser-Arg) on the variable region of the human immunoglobulin light chain.
TP2260 Immunoglobulin M heavy chain (IGHM) fragment [Homo sapiens] Others
Immunoglobulin M heavy chain (IGHM) fragment [Homo sapiens] is a fragment (Gly-Val-Ala-Leu-His-Arg-Pro-Asp-Val-Tyr-Leu-Leu-Pro-Pro-Ala-Arg) on the human immunoglobulin micro heavy chain. Immunoglobulins (Ig) are the anti...
TP2259 immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus] Others
Immunoglobulin light chain variable region fragment [Homo sapiens]/[Mus musculus] is a fragment on the variable region of the human and mouse immunoglobulin light chain. Immunoglobulins (Ig) are the antigen recognition m...
T9917 Denosumab RANKL/RANK
Denosumab is a monoclonal antibody given subcutaneously that inhibits osteoclast activity by targeting the RANK ligand
TP2385 Ige decapeptide Immunoglobulin E decapeptide
Ige decapeptide is a peptide.
T9926 Omalizumab Others
Omalizumab is a recombinant humanized monoclonal antibody against human immunoglobulin E IgE)
T30231 AVP-13358 Others
AVP-13358 is a CD23 antagonist (immunoglobulin ε-Fc receptor antagonist), an immunoglobulin E inhibitor. AVP-13358 has potent activity against IgE, cytokines and CD23 and is used in the treatment of immune system disorde...
T78269 Anti-Mouse PD-1 Antibody (RMP1-14) PD-1/PD-L1
RMP1-14 is an IgG1-like immunoglobulin and anti-Mouse PD-1 antibody that blocks PD-1/PD-L1 signaling.
T30480 BiP inducer X BIX Apoptosis
BiP inducer X (BIX) is a selective inducer of immunoglobulin heavy chain binding protein (BiP)/GRP78 and an ER chaperone inducer. BiP inducer X prevents cell death in neurons and retinal cell lines.
T22889 KF38789 KF 38789 Others
KF38789 is a selective inhibitor of P-selectin-mediated cell adhesion and P-selectin immunoglobulin G chimeric protein.
T76937 Burfiralimab hzVSF-v13 HBV
Burfiralimab (hzVSF-v13) is a monoclonal immunoglobulin (IgG4) directed against waveform proteins that has anti-HBV effects and can be used to study rheumatoid arthritis,
T9907 Nivolumab PD-1/PD-L1
Nivolumab (anti-PD-1) is a genetically engineered fully human immunoglobulin Ig) G4 monoclonal antibody directed against the negative immunoregulatory human cell surface receptor programmed death-1PD-1PCD-1) with immune ...
T39057 Rozanolixizumab UCB7665 Others
Rozanolixizumab (RYSTIGGO) is a high-affinity humanized immunoglobulin G4 monoclonal antibody targeting Fc receptors (FcRn) in human newborns for the study of pathogenic IgG in autoimmune and alloimmune diseases.
T77042 Aducanumab BIIB037 Beta Amyloid
Aducanumab (BIIB037), A selective human immunoglobulin gamma-1 (IgG1) monoclonal antibody, targets the clustered form of amyloid beta (Aβ). Aducanumab shows brain permeability and may be used to treat Alzheimer's disease...
T35392 Tiragolumab RO 7092284,RG6058-10,MTIG-7192A,RG6058-11,RG-6058 Others
Tiragolumab(MTIG-7192A) is a monoclonal antibody that targets T-cell immunoglobulin and the ITIM structural domain (TIGIT).Tiragolumab is often used in combination with the PD-L1 inhibitor, Atezolizumab, for the treatmen...
T76722 Sarilumab REGN-88,SAR-153191 IL Receptor
Sarilumab (SAR-153191)is a potent interleukin-6 IL-6 receptor antagonist and a human immunoglobulin G1 monoclonal antibody. Sarilumab inhibits IL-6-mediated signaling and reduces inflammation.Sarilumab is used for the pr...
T77075 Spartalizumab PDR001 PD-1/PD-L1
Spartalizumab (PDR001) is a humanized immunoglobulin 4 monoclonal antibody that selectively binds to PD-1 at low concentrations and shows high activity. Spartalizumab blocks the interaction with PD-L1 and PD-L2, and can ...
T73133 FGF22-IN-1 Others
FGF22-IN-1 is a potential CD4 N-terminal immunoglobulin variable region-like domain (CD4 D1) inhibitor.FGF22-IN-1 inhibits the interaction between CD4 and major histocompatibility complex (MHC) class II proteins and supp...
T77423 Lirilumab ONO-4483,IPH2102 Virus Protease
Lirilumab (IPH2102) is an antibody against the lethal immunoglobulin-like receptor antibody KIR2D with antitumor activity that enhances the anti-HPV + cervical cancer activity of natural killer cells through VAV1-depende...
T76692 Mosunetuzumab BTCT-4465A Others
Mosunetuzumab (BCT-4465A) is a humanized antibody based on immunoglobulin G1 that targets CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used to stu...
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