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Results for "

immunoglobulin

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    90
    TargetMol | Inhibitors_Agonists
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    1
    TargetMol | Compound_Libraries
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    TargetMol | Inhibitors_Agonists
Omalizumab
T9926242138-07-4
Omalizumab is a recombinant humanized monoclonal antibody against human immunoglobulin E IgE)
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Anti-Rat Kappa Immunoglobulin Light Chain Antibody
Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5)
T9901A-539
Anti-Rat Kappa Immunoglobulin Light Chain Antibody (MAR 18.5) is an IgG2a, κ antibody inhibitor derived from mice and specifically targets the rat κ immunoglobulin light chain.
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2-4 weeks
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Aducanumab
BIIB037
T770421384260-65-4
Aducanumab (BIIB037), A selective human immunoglobulin gamma-1 (IgG1) monoclonal antibody, targets the clustered form of amyloid beta (Aβ). Aducanumab shows brain permeability and may be used to treat Alzheimer's disease (AD).
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TargetMol | Inhibitor Hot
TargetMol
Anti-Mouse PD-1 Antibody (RMP1-14)
Anti-mouse PD-1 (CD279)
T78269
RMP1-14 is an IgG-like immunoglobulin antibody against mouse PD-1 that can block PD-1 PD-L1 signaling; its isotype control antibody is Mouse IgG2a kappa, Isotype Control.
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TargetMol | Inhibitor Hot
Reslizumab
Sch55700, DCP-835, DCP835, CEP-38072, CEP38072
T12706241473-69-8
Reslizumab (Sch 55700) is a humanized immunoglobulin G (IgG)4 κ monoclonal antibody that binds to human interleukin 5, thereby decreasing eosinophil production and survival.Reslizumab improves lung function, induces a decrease in eosinophil production and maturation, and may be used in the study of asthma.
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Tiragolumab
RO 7092284, RG6058-11, RG6058-10, RG-6058, MTIG-7192A
T353921918185-84-8
Tiragolumab(MTIG-7192A) is a monoclonal antibody that targets T-cell immunoglobulin and the ITIM structural domain (TIGIT).Tiragolumab is often used in combination with the PD-L1 inhibitor, Atezolizumab, for the treatment of solid malignant tumors such as non-small cell lung cancer.
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Rozanolixizumab
UCB7665
T390571584645-37-3
Rozanolixizumab (RYSTIGGO) is a high-affinity humanized immunoglobulin G4 monoclonal antibody targeting Fc receptors (FcRn) in human newborns for the study of pathogenic IgG in autoimmune and alloimmune diseases.
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Mosunetuzumab
BTCT-4465A
T766921905409-39-3
Mosunetuzumab (BCT-4465A) is a humanized antibody based on immunoglobulin G1 that targets CD20 (B cells) and CD3 (T cells). Mosunetuzumab redirects T cells to engage and eliminate malignant B cells and can be used to study relapsed or refractory (R R) B-cell non-Hodgkin lymphoma (B-NHL) and refractory follicular lymphoma.
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Sarilumab
Sarilumab (anti-IL-6Rα), SAR-153191, REGN-88
T767221189541-98-7
Sarilumab (SAR-153191)is a potent interleukin-6 IL-6 receptor antagonist and a human immunoglobulin G1 monoclonal antibody. Sarilumab inhibits IL-6-mediated signaling and reduces inflammation.Sarilumab is used for the prevention and treatment of rheumatoid arthritis.
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Galiximab
IDEC114-20, IDEC114, IDEC 114-20, IDEC 114
T76809357613-77-5
Galiximab (IDEC 114) is a primate-type anti-CD80 immunoglobulin G1 (IgG1)-like monoclonal antibody with antitumor activity that induces in vivo growth inhibition and prolongs survival of B-NHL tumor xenografts. Galiximab has been used in the study of hematologic malignancies.
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7-10 days
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Lirentelimab
Antolimab, Anti-Siglec-8 Reference Antibody, AK002, AK 002
T768692283348-97-8
Lirentelimab (AK002) is a humanized anti-sialic acid-binding immunoglobulin-like lectin-8 (Siglec-8) antibody that induces apoptosis of IL-5-activated eosinophils and inhibits IL-5-mediated mast cell activation, and is used in the study of refractory inert systemic mastocytosis and allergic conjunctivitis.
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Narsoplimab
OMS 721
T768702108782-45-0
Narsoplimab (OMS 721) is a selective whole-human immunoglobulin gamma-4 (IgG4) monoclonal antibody and a mannan-binding lectin-associated serine protease-2 (MASP-2) inhibitor that binds MASP-2 to prevent lectin pathway activation and inhibit the agglutinin pathway. It is used to study diseases associated with hematopoietic stem cell transplantation in adults.
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Burfiralimab
hzVSF-v13
T769372460809-80-5
Burfiralimab (hzVSF-v13) is a monoclonal immunoglobulin (IgG4) targeted against waveform proteins, exhibiting anti-HBV properties and potential applications in rheumatoid arthritis research.
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Tozorakimab
MEDI-3506, MEDI3506, MEDI 3506
T769722376858-66-9
Tozorakimab (MEDI-3506) is a human immunoglobulin G1 monoclonal antibody targeting IL-33. It inhibits IL-33 signaling through ST2 and RAGE EGFR, reduces inflammation and epithelial dysfunction, and can be used to study chronic obstructive pulmonary disease.
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7-10 days
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Tosatoxumab
T769731374419-41-6
Tosatoxumab (AR-301; KBSA301), a human immunoglobulin G1 monoclonal antibody, specifically targets and neutralizes S. aureus alpha-toxin (alpha-hemolysin; Hla) by binding to its N-terminal epitope. This interaction blocks the toxin's ability to form functional pore oligomers, crucial for its pathogenic activity. As a result, Tosatoxumab offers promising potential as an adjunctive passive immunotherapy alongside conventional antibiotics for S. aureus pneumonia [1] [2].
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2-4 weeks
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Cirevetmab
T770002473240-98-9
Cirevetmab (ZTS-00521426), a caninized monoclonal antibody targeting Canis lupus familiaris TGFB1, is classified as an immunoglobulin G2-kappa. It functions as an immunomodulator [1].
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Exbivirumab
T77001569658-80-6
Exbivirumab is an anti-hepatitis B virus monoclonal antibody (anti-HBV mAb) that amplifies the antiviral effects of hepatitis B immunoglobulin (HBIG) [1].
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2-4 weeks
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Inbakicept
T770342135939-52-3
Inbakicept is a dimer of IL-15 receptor alpha sushi domain and immunoglobulin G1 (human Fc fragment) fusion protein, which is an IL-15 super agonist protein complex. Inbakicept binds to IL-15 antibody Nogapendekin alfa to form the complex Nogapendekin alfa inbakicept (ALT-803) in a 1:2 ratio. ALT-803 has potential anticancer and anti-tumor activities, which can be used to study breast cancer.
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Lenvervimab
T770562055006-79-4
Lenvervimab (GC1102) is a recombinant human IgG1-type hepatitis B immunoglobulin designed for the research of hepatitis B virus infection [1] [2].
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2-4 weeks
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Spartalizumab
Spartalizumab(anti-PD-1), PDR001
T770751935694-88-4
Spartalizumab (PDR001) is a humanized immunoglobulin G4 monoclonal antibody that selectively binds to PD-1 at low concentrations, exhibiting high activity. It blocks the interaction with PD-L1 and PD-L2, making it suitable for studying undifferentiated thyroid cancer (ATC).
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Lutikizumab
T770771791411-57-8
Lutikizumab (ABT-981) is a dual variable domain immunoglobulin targeting and inhibiting both IL-1α and IL-1β. This compound is under investigation for its potential application in osteoarthritis research [1].
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2-4 weeks
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Dilpacimab
T771571791420-09-1
Dilpacimab (ABT165), a potent dual-variable domain immunoglobulin, targets both the delta-like ligand 4 (DLL4) and VEGF pathways. It has potential applications in cancer research [1].
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2-4 weeks
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Pucotenlimab
T77178
Pucotenlimab (HX008), a humanized immunoglobulin G4 (IgG4) monoclonal antibody targeting programmed cell death protein 1 (anti-PD-1), serves as a potential agent in tumor research [1].
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2-4 weeks
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Remtolumab
T771791791410-27-9
Remtolumab (ABT-122), a dual-variable domain immunoglobulin, neutralizes tumor necrosis factor α (TNFα) and IL-17A, demonstrating dual inhibition of both. This compound is utilized in rheumatoid arthritis (RA) research [1] [2].
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2-4 weeks
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