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Anti-IL-T4 Antibody (8Q805) is a Mouse antibody targeting IL-T4. Anti-IL-T4 Antibody (8Q805) can be used in ELISA.
Pack Size | Price | Availability | Quantity |
---|---|---|---|
100 μL | $199 | 7-10 days |
Description | Anti-IL-T4 Antibody (8Q805) is a Mouse antibody targeting IL-T4. Anti-IL-T4 Antibody (8Q805) can be used in ELISA. |
Alias | MIR-10, MIR10, LIR-2, LIR2, leukocyte immunoglobulin like receptor B2, ILT-4, ILT4, CD85D |
Ig Type | Monoclonal Mouse IgG1 |
Clone | 8Q805 |
Reactivity | Human |
Application | ELISA |
Recommended Dose | ELISA: 1:1000-1:2000 |
Antibody Type | Monoclonal |
Host Species | Mouse |
Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LILRB2 / ILT4 / LIR-2 (rh LILRB2 / ILT4 / LIR-2; TMPY-03284; AAH36827.1; Met1-Val461). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
Purification | Protein A |
Appearance | Liquid |
Formulation | 0.2 μm filtered solution in PBS |
Research Background | ILT4, also known as LILRB2, is a member of the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). ILT4 gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. Multiple transcript variants encoding different isoforms have been found for the ILT4 gene. ILT4 is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. |
Conjucates | Unconjugated |
Immunogen | Recombinant Human LILRB2 / ILT4 / LIR-2 Protein (TMPY-03284) |
Antigen Species | Human |
Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
Transport | Shipping with blue ice. |
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