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Anti-IL-T4 Antibody (5V475)
😃Good
Catalog No. TMAY-02690
Alias MIR-10, MIR10, LIR-2, LIR2, leukocyte immunoglobulin like receptor B2, ILT-4, ILT4, CD85D
Anti-IL-T4 Antibody (5V475) is a Mouse antibody targeting IL-T4. Anti-IL-T4 Antibody (5V475) can be used in ELISA,FCM.
Anti-IL-T4 Antibody (5V475)
Anti-IL-T4 Antibody (5V475)
😃Good
Catalog No. TMAY-02690Alias MIR-10, MIR10, LIR-2, LIR2, leukocyte immunoglobulin like receptor B2, ILT-4, ILT4, CD85D
Anti-IL-T4 Antibody (5V475) is a Mouse antibody targeting IL-T4. Anti-IL-T4 Antibody (5V475) can be used in ELISA,FCM.
| Pack Size | Price | Availability | Quantity |
|---|---|---|---|
| 20 μL | $92 | 7-10 days | |
| 100 μL | $199 | 7-10 days |
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
| Description | Anti-IL-T4 Antibody (5V475) is a Mouse antibody targeting IL-T4. Anti-IL-T4 Antibody (5V475) can be used in ELISA,FCM. |
| Alias | MIR-10, MIR10, LIR-2, LIR2, leukocyte immunoglobulin like receptor B2, ILT-4, ILT4, CD85D |
| Ig Type | Monoclonal Mouse IgG2b |
| Clone | 5V475 |
| Reactivity | Human |
| Verified Activity | Flow cytometric analysis of Human LILRB2(CD85d) expression on human whole blood monocytes. Cells were stained with purified anti-Human LILRB2(CD85d), then a FITC-conjugated second step antibody. The fluorescence histograms were derived from gated events with the forward and side light-scatter characteristics of viable monocytes. |
| Application | ELISA,FCM |
| Recommended Dose | ELISA: 1:1000-1:2000; FCM: 1:25-1:100 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Construction | This antibody was produced from a hybridoma resulting from the fusion of a mouse myeloma with B cells obtained from a mouse immunized with purified, recombinant Human LILRB2 / ILT4 / LIR-2 (rh LILRB2 / ILT4 / LIR-2; TMPY-03284; AAH36827.1; Met1-Val461). The IgG fraction of the cell culture supernatant was purified by Protein A affinity chromatography. |
| Purification | Protein A |
| Appearance | Liquid |
| Formulation | 0.2 μm filtered solution in PBS |
| Research Background | ILT4, also known as LILRB2, is a member of the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). ILT4 gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family. Multiple transcript variants encoding different isoforms have been found for the ILT4 gene. ILT4 is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. |
| Conjucates | Unconjugated |
| Others Formats | APC/FITC/PE |
| Antibody Types Available | 4 |
| Immunogen | Recombinant Human LILRB2 / ILT4 / LIR-2 Protein (TMPY-03284) |
| Antigen Species | Human |
| Biology Area | ITIM/ITAM Immunoreceptors and Related Molecules |
Stability & Storage
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. Preservative-Free. |
| Transport | Shipping with blue ice. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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