Mesothelin

MSLN (Mesothelin) is a cell surface glycoprotein predominantly overexpressed in mesothelial cells and various tumour cells, including ovarian and pancreatic cancers. MSLN plays a crucial role in cell-cell adhesion and signal transduction. Due to its high expression in tumour cells, MSLN has emerged as a prominent target for tumour diagnosis and therapy. High MSLN expression correlates with tumour aggressiveness, drug resistance, and poor prognosis.