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Immunology/Inflammation

Aryl Hydrocarbon Receptor

Immunology/Inflammation related

NOD-like Receptor (NLR)

Prostaglandin Receptor

Reactive Oxygen Species

Thrombopoietin Receptor

TMV

Tobacco mosaic virus (TMV) is a plant virus belonging to the genus Tobamovirus. TMV is a positive-strand single-stranded RNA virus exhibiting high stability and infectivity, capable of infecting numerous plant species, including tobacco, tomato, and pepper. Infection by TMV induces mottled leaf symptoms such as chlorosis, deformation, and necrosis, severely impairing plant growth and yield.

Filter HomeSignaling PathwaysImmunology/InflammationTMV

Yadanziolide A

TN113095258-14-3

Yadanziolide A is a natural product isolated from the cultivated dry seeds of Brucea javanica, has strong antiviral activities with IC50 of 5.5 μM against tobacco mosaic virus. Yadanziolide A shows significant antitumor effects.

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DL-Serine

T8363302-84-1

DL-Serine is a non-essential amino acid and a natural ligand and allosteric activator of pyruvate kinase M2.

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Chaparrinone

T7998422611-34-3

Chaparrinone, a bittersweet analog from Ailanthus altissima (Mill.), has antimalarial, antitumor, and antiviral activities and has been used in the study of tobacco mosaic virus infections and SARS virus infections.

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Antiviral agent 14

T623092755814-80-1

Antiviral agent 14 is an antiviral compound that inhibits tobacco mosaic virus (TMV) with an EC50 of 135.5 μg mL and cucumber mosaic virus (CMV) with an EC50 of 178.6 μg mL.

$1,520

6-8 weeks

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TMV-IN-8

T875383023856-56-3

TMV-IN-8 (compound 7d) is an anti-tobacco mosaic virus (TMV) agent with an antiviral EC50 of 157.6 μg mL. TMV-IN-8 blocks the assembly of TMV by binding with coat protein (Kd = 0.7 μM) and suppresses TMV coat protein gene expression and biosynthesis process [1].

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10-14 weeks

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TMV-IN-1

T733792883408-27-1

TMV-IN-1, a chalcone derivative, serves as an inhibitor of the tobacco mosaic virus (TMV), demonstrating effective therapeutic and protective activities, with EC50 values of 70.7 μg mL and 60.8 μg mL, respectively. This compound is applicable in research related to infection, inflammation, and tumor [1].

$1,520

6-8 weeks

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Rubinaphthin A

TN2162448962-05-8

Rubinaphthin A is a natural product from Rubia cordifolia.

$398

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TMV-IN-5

T792691207318-92-0

TMV-IN-5 (compound 1a) is an antiviral and antifungal agent that inhibits the assembly of the tobacco mosaic virus (TMV) by binding to its coat protein (CP), making it a potential candidate for pesticide formulations [1].

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8-10 weeks

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TMV-IN-9

T88492412315-55-0

TMV-IN-9 (compound A6) is an antiviral agent that exhibits exceptional inactivation effects against Tobacco Mosaic Virus (TMV), with an EC50 of 62.8 μg/mL. It demonstrates strong binding capabilities to the TMV capsid protein, with a binding affinity of 1.862 μM. Moreover, TMV-IN-9 significantly disrupts the integrity of TMV particles, thereby preventing the virus from infecting the host.

$1,520

4-6 weeks

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3-Hydroxy-3-acetonyloxindole

TN293833417-17-3

3-Hydroxy-3-acetonyloxindole is a natural product of Marsdenia, Asclepiadaceae. The catalog number is TN2938 and the CAS number is 33417-17-3. 3-Hydroxy-3-acetonyloxindole can be used as a reference standard.

$1,189

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(±)-Phrymarolin II

T3991823720-86-7

(±)-Phrymarolin II is a promising class of inhibitors that target the tobacco mosaic virus, representing a novel approach in plant virus suppression.

$970

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TMV-IN-4

T750281820823-40-2

TMV-IN-4 (Compound 3), a tobacco mosaic virus (TMV) inhibitor, effectively strengthens plant resistance and tolerance to TMV by binding with the TMV helicase. Furthermore, it boosts activities of peroxidase and superoxide dismutase, augmenting tobacco's resilience to TMV infection [1].

$1,370

8-10 weeks

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TMV-IN-2

T747122883408-32-8

TMV-IN-2, a chalcone derivative, functions as an inhibitor of the tobacco mosaic virus (TMV), exhibiting antiviral properties with an EC50 of 89.9 μg mL. This compound is utilized in investigating infection, inflammation, and tumor research [1].

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8-10 weeks

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7-Deoxy-trans-dihydronarciclasine

T79994145987-74-2

7-Deoxy-trans-dihydronarciclasine is an alkaloid that functions as a tobacco mosaic virus (TMV) inhibitor with an IC50 of 1.80 μM and also serves as an anti-neuroinflammatory agent. This compound reduces Aβ and APP levels in the cerebral cortex of Tg2576 mice [1] [2] [3].

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Yadanzioside L

TN232199132-97-5

Yadanzioside L shows strong antiviral activity.

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Yadanzioside I

TN526799132-95-3

Yadanzioside I shows strong antiviral activity.

$820

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TMV-IN-3

T747132883408-35-1

TMV-IN-3, a chalcone derivative, functions as a tobacco mosaic virus (TMV) inhibitor, exhibiting antiviral activity against TMV with an EC50 of 120.3 μg mL. This compound is applicable for research in infection, inflammation, and tumor [1].

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8-10 weeks

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6-O-Methacrylate

TN3187950685-51-5

6-O-Methacrylate is a natural product for research related to life sciences. The catalog number is TN3187 and the CAS number is 950685-51-5.

$2,500

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trans-3-(3-Pyridyl)acrylic acid

T8755719337-97-4

Trans-3-(3-Pyridyl)acrylic acid (compound 15) is a trans-3-aryl acrylic acid demonstrating antiviral activity against tobacco mosaic virus (TMV) [1].

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10-14 weeks

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TMV-IN-6

T79270

TMV-IN-6 (Compound 4g) is a novel antiviral and fungicidal agent that obstructs tobacco mosaic virus (TMV) assembly by binding to the TMV coat protein (CP) and disrupting the interaction between TMV CP and RNA [1].

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