Nectin-4

Nectin-4 is a cell adhesion molecule belonging to the Nectin family, primarily expressed in epithelial and neural cells. Through interactions with other Nectin family members, Nectin-4 participates in intercellular adhesion and polarity formation. In oncology, Nectin-4 exhibits high expression in multiple cancers, including bladder, breast, and lung cancers, making it a potential target for tumour diagnosis and therapy.