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CNTO4088
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Catalog No. T9901A-1010
CNTO4088 is a highly specialized monoclonal antibody target the human interleukin-23 cytokine with exceptional binding affinity and selectivity, neutralization of the p19 subunit-mediated biological activities across various preclinical experimental models of autoimmune inflammation to evaluate the functional role of the Th17 signaling axis in pathological tissue remodeling during strictly monitored laboratory observation periods.
CNTO4088
CNTO4088
Copy Product Info😃Good
Catalog No. T9901A-1010
CNTO4088 is a highly specialized monoclonal antibody target the human interleukin-23 cytokine with exceptional binding affinity and selectivity, neutralization of the p19 subunit-mediated biological activities across various preclinical experimental models of autoimmune inflammation to evaluate the functional role of the Th17 signaling axis in pathological tissue remodeling during strictly monitored laboratory observation periods.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 1 mg | Inquiry | Inquiry | Inquiry | |
| 5 mg | Inquiry | Inquiry | Inquiry |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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| Description | CNTO4088 is a highly specialized monoclonal antibody target the human interleukin-23 cytokine with exceptional binding affinity and selectivity, neutralization of the p19 subunit-mediated biological activities across various preclinical experimental models of autoimmune inflammation to evaluate the functional role of the Th17 signaling axis in pathological tissue remodeling during strictly monitored laboratory observation periods. |
| In vitro | In X-ray crystallography and binding assays, CNTO4088 exhibited a noncanonical conformation of the CDR L1 loop while maintaining high binding affinity for the IL-23 cytokine [1]. |
| Reactivity | Human |
| Application | FACS Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Uniprot ID | |
| Target | IL-23 |
| Isotype | IgG1 |
| Storage | store at low temperature | store at -20°C | Shipping with blue ice/Shipping at ambient temperature. |
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