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Elimusertib (BAY-1895344) is a potent, highly selective, and orally available ATR inhibitor with an IC50 of 7 nM, demonstrating significant anti-tumor efficacy as a monotherapy and strong combination potential with targeted alpha therapy Radium-223 dichloride.

NVP-ADW742 (ADW) is an IGF-1R inhibitor with IC50 of 0.17 μM, >16-fold more potent against IGF-1R than InsR; little activity to HER2, PDGFR, VEGFR-2, Bcr-Abl and c-Kit.

CB-5083 is a potent, selective, and orally bioavailable p97 AAA ATPase inhibitor ( IC50=11 nM).

Flunisolide hemihydrate is a corticosteroid, an orally active Glucocorticoid receptor activator with anti-inflammatory effects. flunisolide hemihydrate induces apoptosis in eosinophils and can be used in asthma or rhinitis, inflammatory diseases. Can be used in studies related to asthma or rhinitis, inflammation.

Phomopsolide B is a useful organic compound for research related to life sciences. The catalog number is T123828 and the CAS number is 97529-84-5.

Achalensolide is a useful organic compound for research related to life sciences. The catalog number is T124039 and the CAS number is 87302-42-9.

Phomopsolidone B is a useful organic compound for research related to life sciences. The catalog number is T125670 and the CAS number is 1622333-85-0.

Carnegine (Pectenine, N-Methylsalsolidine) is a useful organic compound for research related to life sciences and the catalog number is T131396.

Isosalsolidine is a useful organic compound for research related to life sciences and the catalog number is T131573.

Flunisolide (Rhinalar) is a synthetic corticosteroid with anti-inflammatory and antiallergic properties.

(S)-Salsolidine, a chemical compound, functions as a weak inhibitor of monoamine oxidase (MAO), exhibiting an inhibition constant (K i ) of 63 μM. R enantiomer demonstrating a greater efficacy than (S)-Salsolidine, boasting a K i value of 26 μM compared to the S form.

Canadensolide, an antifungal metabolite of *Penicillium canadense*.

Solidagonic acid, by inhibiting HSET motor activity, promotes the conversion of abnormal monopolar spindles to bipolar configurations, effectively suppressing fission yeast cell death and facilitating the mitotic spindles' reversion from monopolar to bipolar morphology. Additionally, this compound demonstrates growth inhibitory effects on the seedlings of Lactuca sativa L. and Lolium multiflorum Lam [1] [2].

Solidagolactone III, an active compound, can be isolated from the genus Solidago [1].

Solidagolactone II, a chlorinated diterpene, has been isolated from Solidago virgaurea L. [1].

Pinusolide is a platelet activating factor ( PAF) antagonist, it may prove of therapeutic value in the treatment of hypotension, it has antileukemic potential, and could be used to treat neurodegenerative diseases. Pinusolide attenuates blockade of insulin signaling by enhancing IRS-1 tyrosine phosphorylation by the activating the AMPK pathway, indicates the targeting of AMPK represents a new therapeutic strategy for hyperglycemia-induced insulin resistance and type 2 diabetes.

Irisolidone is a potent volume-regulated anion channel (VRAC) current inhibitor, it exhibits high efficacy for VRAC blockade with IC50s of 5-13 μM.

15-Methoxypinusolidic acid has anti-inflammatory effects, it inhibits LPS-induced iNOS expression and NO production, independent on MAPK and NF-kappaB. 15-Methoxypinusolidic acid suppresses adipocyte differentiation through the inhibition of PPARgamma-dep

Pinusolidic acid shows a potent inhibitory effect on platelet activating factor (PAF) binding to rabbit platelets (IC50 = 2.3 x 10(-5) M, 7.48 + - 2.11 micrograms ml).

Irisolidone 7-O-β-D-glucopyranoside is a flavonoid compound derived from Pueraria lobata.

Irisolidone 7-O-glucoside is a natural product that can be used in related research in the field of life sciences. Its product number is TN8520.

Goyazensolide is a sesquiterpene lactone compound with anti-inflammatory and anticancer properties. It can be isolated and extracted from the Argentine herbaceous plant, Centratherum punctatum.

RMC-7977 is a highly selective inhibitor of the active (GTP-bound) forms of KRAS, HRAS, and NRAS with anticancer activity for the study of solid tumors with KRAS G12C mutations.

Osunprotafib (ABBV-CLS-484) is a potent, orally bioavailable PTP1B PTPN2 inhibitor in clinical trials for solid tumors. [1] Osunprotafib (ABBV-CLS-484) stimulates the tumor microenvironment and promotes natural killer cell and CD8 T cell function and enhances T cell anti-tumor immunity by enhancing JAK-STAT signaling and reducing T cell dysfunction. [2]