dap

N-Boc-Val-Dil-Dap-Doe is used in the synthesis of Dolastatin 10, a potent antimitotic peptide that inhibits tubulin polymerization.

Fmoc-Dap(Boc)-OH, an amino acid derivative featuring an Fmoc protecting group, is utilized in the synthesis of bicyclic peptide tachykinin NK2 antagonists.

Mal-L-Dap(Boc)-Osu is an ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs).

Boc-Dap-NE used in the synthesis of antibody-drug conjugates (ADCs).It is a cleavable ADC linker

Boc-Dap(Z)-OH is an amino acid derivative and has a wide range of applications in life science related research.

Fmoc-Dap(Alloc)-OH is a useful organic compound for research related to life sciences. The catalog number is T66725 and the CAS number is 188970-92-5.

Z-Dap-OH is an amino acid derivative and has a wide range of applications in life science related research.

DAP-81 is a diaminopyrimidine derivative that targets PLKs, destabilizing kinetochore microtubules. Other spindle tubules are stabilized, resulting in monopolar mitotic spindles. In vitro, DAP-81 inhibits Plk1 at an IC50 of 0.9 nM. DAP-81 is currently in ongoing preclinical evaluations.

18:0 DAP can be utilized in the formulation of lipid nanoparticles (LNPs) that encapsulate mRNA within their core [1].

1,2-Dimyristoyl-3-dimethylammonium-propane (14:0 DAP) is a cationic lipid utilized in drug delivery [1].

iE-DAP is a biologically active peptide that functions as a NOD1 agonist.

Mca-(endo-1a-Dap(Dnp))-TNF-Alpha (-5 to +6) amide (human) is a peptide used as a fluorescence resonance energy transfer (FRET) based substrate for proteolytic activity assays, with cleavage-induced changes in fluorescence intensity indicating enzymatic activity [1].

Boc-Val-Dil-Dap-OH is a cleavable linker utilized in the synthesis of antibody-drug conjugates (ADCs), facilitating the connection between the antibody and the therapeutic drug [1].

Dap-NE hydrochloride, a dipeptide hydrochloride and cleavable ADC linker, facilitates the synthesis of Antibody-Drug Conjugates (ADCs) by connecting antibody molecules to cytotoxins [1].

Boc-NMe-Val-Val-Dil-Dap-OH serves as a cleavable ADC linker, facilitating the synthesis of antibody-drug conjugates (ADCs).

Boc-Val-Dil-Dap-Phe-OMe serves as a cleavable ADC linker in the production of antibody-drug conjugates (ADCs) [1].

Fmoc-L-Dap(Poc)-OH is an amino acid building block equipped with an azide group, designed for side-chain Click conjugation using standard protocols and for copper-free Click conjugation with tetrazine linkers through the Diels-Alder method [1].

Fmoc-DAP-N3 is an azide-containing click chemistry reagent characterized by a short linear spacer molecule with an Fmoc-protected amine function. It is utilized for click coupling with small molecules and the formation of amide bonds or for bioconjugation with proteins and antibodies.

Fmoc-L-Dap(Pentynoyl)-OH is a click chemistry reagent featuring an alkyne group, which facilitates the introduction of alkyne functionality into peptide sequences through standard Fmoc tBu procedures. As an amino acid building block, this compound enables copper-catalyzed azide-alkyne cycloaddition (CuAAC) with azide-containing organic molecules or copper-free coupling reactions with tetrazines. The presence of the pentynoyl group allows for versatile applications in peptide synthesis and modification.

Z-L-Dap(N3)-OH is a click chemistry reagent that features an azido group. Click chemistry is widely utilized in the conjugation between nucleic acids, lipids, proteins, and other molecules due to its high yield, high specificity, and simplicity, making it immensely beneficial across various research domains.

N3-L-Dap(Boc)-OH is a click chemistry reagent featuring an azide group. Click chemistry is a robust set of reactions known for excellent biocompatibility, rapidity, and high specificity in biological environments. This reagent can participate in copper-catalyzed azide-alkyne cycloaddition reactions (CuAAc) with molecules that contain an alkyne group. It is also capable of strain-promoted alkyne-azide cycloaddition reactions (SPAAC) with molecules possessing DBCO or BCN groups.

N3-D-Dap(Fmoc)-OH is a click chemistry reagent employed both as a component in copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions and as an orthogonal protective derivative of diamino carboxylic acids. This dual functionality facilitates its use in diverse synthetic applications.

Fmoc-D-Dap(Boc)-OH, an amino acid derivative featuring an Fmoc protecting group, is utilized in the synthesis of bioactive peptide mimetics, including DOTA-modified peptides and their metal chelates, which are noted for their cancer diagnostic capabilities.

16:0 DAP is a cationic lipid that can serve as a drug delivery vector.