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Anti-DAPK1 Antibody (8G920)
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Catalog No. TMAB-04976
Anti-DAPK1 Antibody (8G920) is a Mouse antibody targeting DAPK1. Anti-DAPK1 Antibody (8G920) can be used in WB.
Anti-DAPK1 Antibody (8G920)
Anti-DAPK1 Antibody (8G920)
Copy Product Info😃Good
Catalog No. TMAB-04976
Anti-DAPK1 Antibody (8G920) is a Mouse antibody targeting DAPK1. Anti-DAPK1 Antibody (8G920) can be used in WB.
| Pack Size | Price | USA Warehouse | Global Warehouse | Quantity |
|---|---|---|---|---|
| 50 μL | $223 | 7-10 days | 7-10 days | |
| 100 μL | $373 | 7-10 days | 7-10 days |
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In Stock Estimated shipping dateUSA Warehouse[1-2 days] Global Warehouse[5-7 days]
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Antigen Details
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| Description | Anti-DAPK1 Antibody (8G920) is a Mouse antibody targeting DAPK1. Anti-DAPK1 Antibody (8G920) can be used in WB. |
| Ig Type | IgG2a, κ |
| Clone | 8G920 |
| Reactivity | Human (predicted:Mouse) |
| Verified Activity | Sample: Lane 1: A549 cell lysates Primary: Anti-DAPK1 (TMAB-04976) at 1/4000 dilution Secondary: IRDye800CW Goat Anti-Mouse IgG at 1/20000 dilution Predicted band size: 160 kD Observed band size: 160 kD |
| Application | |
| Recommended Dose | WB: 1:500-2000 |
| Antibody Type | Monoclonal |
| Host Species | Mouse |
| Subcellular Localization | Cytoplasm. Colocalizes with the actin filament system. |
| Tissue Specificity | Isoform 2 is expressed in normal intestinal tissue as well as in colorectal carcinomas. |
| Construction | Hybridoma Monoclonal Antibody |
| Purification | Protein G purified |
| Appearance | Liquid |
| Formulation | 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol. |
| Concentration | 1mg/ml |
| Research Background | DAPK1 expression is frequently lost in human carcinomas and B-cell leukemia, and lower levels of expression correlates with high rates of metastasis. The loss of DAPK expression provides a link between suppression of apoptosis and metastasis. DAPK1 is thought be involved in an early apoptotic checkpoint which eliminates premalignant cells from cancer formation. Studies in bladder cancer patients have also shown that hypermethylation of DAPK1 correlates to high recurrence rates and thus DAPK1 may be used as a prognostic marker. DAPK1 is also reportedly a molecular regulator of neuronal death in epilepsy. |
| Immunogen | KLH conjugated synthetic peptide: human DAPK1 |
| Antigen Species | Human |
| Gene Name | DAPK1 |
| Gene ID | |
| Protein Name | Death-associated protein kinase 1 |
| Uniprot ID | |
| Function | Calcium/calmodulin-dependent serine/threonine kinase which acts as a positive regulator of apoptosis. |
| Molecular Weight | Theoretical: 160 kDa. |
| Stability & Storage | Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles. |
| Transport | Shipping with blue ice. |
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