T28918 |
Talviraline
|
163451-80-7
|
98%
|
|
Talviraline is an RNA-induced DNA polymerase inhibitor.Talviraline is a potent inhibitor of HIV-1-induced cell killing and HIV-1 replication in a variety of huma...
|
T27112 |
Cytembena
|
21739-91-3
|
98%
|
|
Cytembena is a cytostatic and a carcinogenic compound that may increase the incidence of fibroadenomas.Cytembena broadly inhibits DNA biosynthesis.
|
T77520 |
AOH1996
|
2089314-64-5
|
98%
|
|
AOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen), targeting the transcription-replication conflict (TRC...
|
T25466 |
GS-9191
|
859209-84-0
|
98%
|
|
GS-9191 is a potent inhibitor of DNA polymerase alpha and ß , a prodrug of the novel nucleoside analogue 9-(2-phosphonomethoxyethyl)guanine (PMEG) , which penetr...
|
T67731 |
Holomycin
|
488-04-0
|
98%
|
|
Holomycin is a secondary metabolite of dithiopyrrolidone. HolomycinHolomycin, an antibiotic secondary metabolite, is required for the biofilm formation of natura...
|
T12935 |
SMN-C3
|
1449597-34-5
|
98%
|
|
SMN-C3 is an orally active modulator of SMN2 splicing, and has the potential to treat spinal muscular atrophy (SMA).
|
T28762 |
Setrobuvir
|
1071517-39-9
|
98%
|
|
Setrobuvir is an orally active non-nucleoside HCV NS5B polymerase inhibitor with inhibitory effects on de novo RNA synthesis and primer extension with IC50s betw...
|
T14313 |
Apricitabine
|
160707-69-7
|
98%
|
|
Apricitabine is a highly selective and orally active HIV-1 reverse transcriptase inhibitor (Ki=0.08 μM), the (-) enantiomer of 2′-deoxy-3′-oxy-4′-thiocytidine (d...
|
T22319 |
DTP3
|
1809784-29-9
|
98%
|
|
DTP3 is a selective MKK7/GADD45β inhibitor, which inhibits cancer-selective NF-κB survival pathway.
|
T2627 |
Nolatrexed dihydrochloride
|
152946-68-4
|
98%
|
|
Nolatrexed Dihydrochloride is the dihydrochloride salt of nolatrexed, a water-soluble lipophilic quinazoline folate analog with antineoplastic activity. Nolatrex...
|
T4187 |
Gemcitabine monophosphate sodium salt hydrate
|
1638288-31-9
|
98%
|
|
Gemcitabine monophosphate disodium salt is a monophosphate derivative of Gemcitabine.
|
T3340 |
SCR7
|
1533426-72-0
|
98%
|
|
SCR7, a specific DNA Ligase IV inhibitor, blocks nonhomologous end-joining (NHEJ).
|
T5539 |
GS-443902
|
1355149-45-9
|
98%
|
|
GS-441524 was shown to be a safe and effective treatment for feline infectious peritonitis (FIP). The optimum dosage was found to be 4.0 mg/kg SC q24h for at lea...
|
TN4394 |
Kobophenol A
|
124027-58-3
|
98%
|
|
Kobophenol A has antimicrobial, and anti-inflammatory activities, it might be a candidate for treatment of inflammatory bone diseases relevant to osteoblast cell...
|
TN4938 |
Samidin
|
477-33-8
|
98%
|
|
Samidin has anti-inflammatory properties through suppression of NF-κB and AP-1-mediated-genes in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells.
|
TN4038 |
Eupatolide
|
6750-25-0
|
98%
|
|
Eupatolide is isolated from the flowers of Inula japonica with anti-inflammatory activity. Eupatolide can be used in studies about TRAIL resistance in breast can...
|
TN3587 |
Capillarisin
|
56365-38-9
|
98%
|
|
Capillarisin is a novel blocker of STAT3 activation and thus may have a potential in negative regulation of growth, metastasis, and chemoresistance of tumor cell...
|
T7429 |
Datelliptium chloride
|
105118-14-7
|
98%
|
|
Datelliptium chloride is a DNA-intercalating agent derived from ellipticine. Datelliptium chloride shows anti-tumor activities.
|
TN4913 |
Riddelline
|
23246-96-0
|
98%
|
|
Riddelline is a potent genotoxic agent in vitro and induces significant elevations in unscheduled DNA synthesis and S-phase synthesis in rat liver.
|
TN3691 |
Communic acid
|
2761-77-5
|
98%
|
|
Communic acid has antibacterial activity, including against mycobacterial. trans-Communic acid has potential to be utilized as anti-wrinkling agents and cosmetic...
|