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Results for "

dc-a

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    196
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Deoxycholic acid
Desoxycholic acid, Deoxycholate, DCA, Cholorebic, Cholerebic, Cholanoic Acid
T296583-44-3
Deoxycholic acid (Cholanoic Acid) is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.
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Sodium dichloroacetate
Sodium Dichloroacetate, Sodium dichloroacetate (DCA), Sodium bichloroacetic acid, DCA sodium salt
T36042156-56-1
Sodium dichloroacetate (BCA) , a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion channel axis, trigger apoptosis in cancer cells, and inhibit tumor growth.
  • $31
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1β-Hydroxydeoxycholic acid
1β-OH-DCA
TN759280434-32-8
1β-Hydroxydeoxycholic acid (1β-OH-DCA), recognized as a secondary bile acid, serves as a biomarker for CYP3A. This compound is metabolized from deoxycholic acid specifically by CYP3A4 and CYP3A7 through recombinant human CYP450 enzymes [1].
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(-)-Epigallocatechin Gallate
Epigallocatechol Gallate, EGCG
T2988989-51-5
(-)-Epigallocatechin Gallate (EGCG) is a phenolic antioxidant polyphenol flavonoid found in plants such as green and black tea, which inhibits telomerase and DNA methyltransferase, blocks the activation of EGF receptors and HER-2 receptors, inhibits cellular oxidation, and prevents free radical damage to cells.
  • $43
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Tauroursodeoxycholate
Ursodeoxycholyltaurine, UR 906, TUDCA, Tauroursodeoxycholic Acid, Taurolite
T253214605-22-2
Tauroursodeoxycholate (UR 906), also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. Tauroursodeoxycholate is the more hydrophilic form of ursodeoxycholic acid, which is the more abundant naturally produced bile acid in humans.Tauroursodeoxycholate is being investigated for use in several conditions such as Primary Biliary Cirrhosis (PBC), insulin resistance, amyloidosis, Cystic Fibrosis, Cholestasis, and Amyotrophic Lateral Sclerosis.
  • $37
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Glycochenodeoxycholic Acid
Lithocholylglycine, Glycochenodeoxycholate, Glycine chenodeoxycholate, GCDCA, Chenodeoxycholylglycine
T4588640-79-9
Glycochenodeoxycholic Acid (Lithocholylglycine) is a glycine conjugate of lithocholic acid, a bile acid. It is increased in livers of mice that are fed diets supplemented with ursadeoxycholic acid. Glycolithocholic acid levels are decreased in lean mice treated with obestatin. Serum glycolithocholic acid levels increase with age in children.
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Ursodeoxycholic acid sodium
Ursodiol sodium, Ursodeoxycholic Acid (sodium salt), Ursodeoxycholate sodium, UDCA sodium, UDCA Na, Sodium Ursodeoxycholate
T290782898-95-5In house
Ursodeoxycholic acid sodium (Sodium Ursodeoxycholate) is a naturally occurring secondary bile acid with anti-inflammatory and cytoprotective activities. Ursodeoxycholic acid sodium acts as signaling molecule, exerting its effects by interacting with bile acid activated receptors,
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Folinic acid calcium
Wellcovorin, Leucovorin Calcium, Folinic acid calcium salt, Calcium folinate
T01481492-18-8
Folinic acid calcium (Leucovorin Calcium) is the active metabolite of folic acid. Leucovorin is used principally as an antidote to folic acid antagonists.
  • $42
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Ursodeoxycholic acid
Ursodiol, UDCA
T0700128-13-2
Ursodeoxycholic acid (UDCA) is a potent inhibitor of liver-specific fatty acid transporter 5 (FATP5). Ursodeoxycholic acid inhibits cholesterol absorption and is used to dissolve gallstones.
  • $42
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Catechin
D-Catechin, Cianidanol, Catechuic acid, Catechinic acid, (+)-Catechin
T0822154-23-4
Catechin (Cianidanol) is a flavan-3-ol, a type of natural phenol and antioxidant.
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Chenodeoxycholic acid
Chenodiol, CDCA
T0847474-25-9
Chenodeoxycholic acid (CDCA) is a bile acid that inhibits 11β-HSD2 with an IC50 value of 22 mM. Chenodeoxycholic acid acts as a detergent to dissolve fat for intestinal absorption and is reabsorbed by the small intestine. Chenodeoxycholic acid is used as a choledocholithiasis, choledocholithiasis and laxative, as well as to prevent or dissolve gallstones.
  • $31
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(+)-Camphor
D-Camphor, D-(+)-Camphor, (1R)-(+)-Camphor
T0882464-49-3
(+)-Camphor (D-Camphor) is the oil extracted from the wood of the Camphor tree Cinnamomum Camphora with anti-inflammatory and analgesic properties.
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D-Carnitine hydrochloride
(S)-Carnitine Hydrochloride
T220310017-44-4
D-Carnitine hydrochloride ((S)-Carnitine Hydrochloride) is a component of striated muscle and liver, used therapeutically to stimulate gastric and pancreatic secretions and to treat hyperlipoproteinemias.
  • $38
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Tanshinone IIA sulfonate sodium
Tanshinone IIA sulfonate, Tanshinone IIA sodium sulfonate, Sodium Tanshinone IIA sulfonate
T294669659-80-9
Tanshinone IIA sulfonate sodium (Tanshinone IIA sodium sulfonate) is a water-soluble derivative of tanshinone IIA extracted from Savia miltiorrhiza; a potent negative allosteric modulator of the human purinergic receptor P2X7. Tanshinone IIA sulfonate sodium (12.5 μM) inhibits hypoxia-induced PKG and PPAR-γ downregulation in PASMCs and distal pulmonary arteries of rats.
  • $39
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Hyodeoxycholic acid
α-Hyodeoxycholic Acid, NSC 60672, HDCA
T296883-49-8
Hyodeoxycholic acid (NSC 60672) has been used in trials studying the treatment of Hypercholesterolemia.
  • $35
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Taurochenodeoxycholic Acid
TCDCA, Taurochenodeoxycholate, Chenyltaurine, Chenodeoxycholyltaurine, 12-Deoxycholyltaurine
T2A2481516-35-8
Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.
  • $39
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D-Pantothenic acid hemicalcium salt
Vitamin B5 calcium salt, D-Pantothenic Acid Calcium, Calpanate, Calcium pantothenate, Calcium D-pantothenate, Calcium D-Panthotenate
T3551137-08-6
D-Pantothenic acid hemicalcium salt (Calcium pantothenate), a kind of water soluble vitamin, can reduce the patulin content of the apple juice.
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Calcium 2-hydroxy-4-(methylthio)butanoate
calcium hydroxymethionine, 2-Hydroxy-4-(methylthio)butyric acid calcium salt
T50824857-44-7
Calcium 2-hydroxy-4-(methylthio)butanoate (Calcium 2-hydroxy-4-(calcium hydroxymethionine)) is a solid, water-soluble, weakly acidic nutrition enhancer (based on its pKa). This compound, also known as 2-Hydroxy-4-(methylthio)butanoic acid, has been primarily detected in urine and is mainly located in the cytoplasm and adiposome of cells.
  • $41
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Calcium L-Threonate
L-Threonic acid Calcium Salt
T521670753-61-6
L-Threonic acid Calcium Salt is an anti-osteoporotic that stimulates ascorbic acid absorption and is commonly used in calcium supplements.
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Glycoursodeoxycholic acid
Ursodeoxycholylglycine, GUDCA
T523464480-66-6
Glycoursodeoxycholic acid (Ursodeoxycholylglycine) is an acyl glycine and a bile acid-glycine conjugate. It is a secondary bile acid produced by the action of enzymes existing in the microbial flora of the colonic environment. In hepatocytes, both primary and secondary bile acids undergo amino acid conjugation at the C-24 carboxylic acid on the side chain, and almost all bile acids in the bile duct, therefore, exist in a glycine conjugated form. Bile acids are steroid acids found predominantly in bile of mammals.
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2,5-Furandicarboxylic acid
Dehydromucic Acid, 2,5-Dicarboxyfuran
T52753238-40-2
2,5-Furandicarboxylic acid (Dehydromucic Acid) is a normal urinary metabolite in humans. 2,5-Furandicarboxylic acid is also a microbial metabolite, a product of the oxidation of hydroxymethylfurfural (HMF) by the enzyme furfural/HMF oxidoreductase which is found in the bacterium Cupriavidus basilensis.
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Mupirocin calcium hydrate
BRL-4910A calcium hydrate
T8148115074-43-6
Mupirocin calcium hydrate is an antibiotic produced by Pseudomonas fluorescens, showed a high level of activity against staphylococci and streptococci and against certain gram-negative bacteria
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Tauroursodeoxycholate dihydrate
UR 906 dihydrate, TUDCA dihydrate, Tauroursodeoxycholic acid dihydrate, Taurolite dihydrate
T16998117609-50-4
Tauroursodeoxycholate (TUDCA ,Taurolite) dihydrate is a water-soluble bile acid with endoplasmic reticulum stress inhibitory, mitochondrial stabilizing, and anti-apoptotic effects, which significantly reduces the expression of apoptotic molecules, such as Caspase-3 and Caspase-12, and inhibits ERK, reducing endoplasmic reticulum stress mediated cell death.
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Isochenodeoxycholic acid
isoCDCA
T207107566-24-5
Isochenodeoxycholic acid (isoCDCA), a bile acid and primary metabolite of ursodeoxycholic acid (UDCA), Isochenodeoxycholic acid exerts protective effects against ethanol-induced damage in HepG2 hepatocytes.
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