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Results for "

dc-a

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    84
    TargetMol | Inhibitors_Agonists
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    1
    TargetMol | Peptide_Products
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    1
    TargetMol | Dye_Reagents
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    TargetMol | PROTAC
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    TargetMol | Inhibitors_Agonists
ddC-AZT dimer
ddC-AZT-dimer, ddCAZT dimer, ddC AZT-dimer, ddC AZTdimer
T31231121892-89-5
ddC-AZT dimer is a biochemical.
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Deoxycholic acid
Desoxycholic acid, Deoxycholate, DCA, Cholorebic, Cholerebic, Cholanoic Acid
T296583-44-3
Deoxycholic acid (Cholanoic Acid) is a bile acid formed by bacterial action from cholate. It is usually conjugated with glycine or taurine. Deoxycholic acid acts as a detergent to solubilize fats for intestinal absorption, is reabsorbed itself, and is used as a choleretic and detergent.
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sodium dichloroacetate
Sodium Dichloroacetate, Sodium dichloroacetate (DCA), Sodium bichloroacetic acid, DCA sodium salt
T36042156-56-1
Sodium dichloroacetate (BCA) , a specific inhibitor of pyruvate dehydrogenase kinase (PDK) with IC50 values of 183 and 80 μM for PDK2 and PDK4 respectively, has been shown to derepress a mitochondrial potassium-ion channel axis, trigger apoptosis in cancer cells, and inhibit tumor growth.
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Bucladesine sodium
Sodium dibutyryl cAMP, Dibutyryl-cAMP sodium salt, Dibutyryl-cAMP, DC2797, dbcAMP, Bucladesine sodium salt, Bucladesine
T141816980-89-5
Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties. Bucladesine sodium is also a cAMP-dependent protein kinase (PKA) activator and a phosphodiester (PDE) inhibitor. Bucladesine sodium has anti-inflammatory activity.
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TargetMol | Inhibitor Hot
SJ6986
T412572765625-93-0In house
SJ6986 is a potent, selective, and orally active GSPT1 2 degrader, effectively degrading GSPT1 with a DC50 of 2.1 nM (D max 99%) [1].
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10-14 weeks
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DC 07090
DC-07090, DC07090
T85337879070-72-1In house
DC 07090 is a human enterovirus 71 3C protease inhibitor with antiviral activity for the study of nucleic acid virus infections.
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MS170
T399282376136-61-5In house
MS170 is a highly effective and specific PROTAC AKT degrader compound that exhibits potent activity. It efficiently reduces the levels of total AKT (T-AKT) within cells, with a DC 50 value of 32 nM. Furthermore, MS170 demonstrates strong binding affinity towards AKT isoforms, specifically AKT1, AKT2, and AKT3, with respective dissociation constants (Kd) of 1.3 nM, 77 nM, and 6.5 nM.This compound is unstable in powder form and other related salt forms are recommended.
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3-6 months
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N4-Benzoyl-2′-deoxycytidine
T79614836-13-9
N4-Benzoyl-2′-deoxycytidine is a synthetic nucleoside analog of the natural nucleoside deoxycytidine (dC), a competitive inhibitor of DNA polymerase. In vitro studies have shown that it inhibits replication in viruses, bacteria and eukaryotic cells. It has also been shown to inhibit tumor cell growth in animal models.
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TargetMol | Inhibitor Sale
Glutathione synthesis-IN-1
T99782632968-72-8
Glutathione synthesis-IN-1 (DC-1) is an inhibitor of glutathione synthesis[1].
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6-8 weeks
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TargetMol | Inhibitor Sale
DC-5163
T10966897771-47-0
DC-5163 is a potent inhibitor of glyceraldehyde 3-phosphate dehydrogenase (GAPDH) with IC50 of 176.3 nM and Kd of 3.192 μM. DC-5163 selectively inhibits cancer cell proliferation and induces apoptosis, and partially inhibits the glycolysis pathway.
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6-8 weeks
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DC-05
T15080890643-16-0
DC-05 is an inhibitor of DNA methyltransferase 1 (DNMT1) (IC50 and a Kd: 10.3 μM and 1.09 μM, respectively).
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PROTAC FGFR2 degrader 1
T200117
PROTAC FGFR2 degrader 1 (compound N5) is a potent PROTAC that efficiently targets FGFR2, boasting a DC 50 value of 6.46 nM and an FGFR2 IC 50 of 0.08 nM. This compound exhibits significant anti-proliferative effects and high selectivity. It induces G0 G1 arrest in the cell cycles of KATOIII and SNU16 and inhibits apoptosis by diminishing the activation of p-ERK and p-PLCγ, the downstream proteins of FGFR2. Additionally, PROTAC FGFR2 degrader 1 maintains over 50% inhibition of gastric cancer cells at a concentration of 0.17 nM and effectively suppresses the growth of SNU16 xenograft tumors in a mouse model.
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HPK1-IN-47
T2003202893885-42-0
HPK1-IN-47, a PROTAC HPK1 degrader (DC 50: 23 nM in PBMCs), serves as a precursor for the synthesis of compounds like PROTAC HPK1 Degrader-2. It is utilized in research focused on diseases mediated by HPK1, including cancer.
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DC-159a
T204310931411-93-7
DC-159a, an 8-methoxy fluoroquinolone, possesses broad-spectrum antibacterial activity, with a particular efficacy against Gram-positive pathogens. The MIC90 values for DC-159a are 0.5 μg mL against Streptococcus anginosus group, 4 μg mL against Clostridium difficile, and 2 μg mL against Bacteroides fragilis.
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10-14 weeks
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di-Val-L-dC
diVal-LdC
T27185380886-96-4
Di-Val-L-dC, a reverse transcriptase inhibitor, is used potentially for treatment of HBV infection.
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Calonyctin A-2b
DC-2b
T30696151864-97-0
Calonyctin A-2b is one of two components of calonyctin A.
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Calonyctin A-2d
DC-2d
T30697151864-96-9
Calonyctin A-2d is one of two components of calonyctin.
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Triocacarcinone A
Trioxacarcin A(sub 2), DC-45 A(sub 2), Antibiotic DC 45 A(sub 2)
T3495381552-35-4
Triocacarcinone A is a biochemical.
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DC-Chol hydrochloride
DC-Cholesterol hydrochloride, DC-Chol (hydrochloride)
T35941166023-21-8
DC-Chol hydrochloride(DC-Cholesterol hydrochloride) inhibited the formation of Aβ40 fibrils under appropriate experimental conditions and significantly inhibited amyloid formation from oxidized hCT in a dose-dependent manner.DC-Chol hydrochloride induces an improved and balanced immunity, which could contribute to hepatitis B vaccine research.
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7-10 days
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DMT-dC(ac) Phosphoramidite
T36753154110-40-4
DMT-dC(ac) Phosphoramidite is a modified phosphoramidite monomer designed for oligonucleotide synthesis.
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7-10 days
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5'-O-DMT-N4-Ac-2'-F-dC
5'-O-DMT-N4-Ac-2'-F-dC
T37136159414-98-9
5'-O-DMT-N4-Ac-2'-F-dC, a modified nucleoside, is utilized for synthesizing DNA or RNA.
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5'-O-DMT-N4-Bz-2'-F-dC
5'-O-DMT-N4-Bz-2'-F-dC
T37137146954-77-0
5'-O-DMT-N4-Bz-2'-F-dC is a nucleoside with protective and modification effects.
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5'-O-DMT-N4-Bz-5-Me-dC
DMT-NBZ-5-METHYL DC
T37138104579-03-5
5'-O-DMT-N4-Bz-5-Me-dC (DMT-NBZ-5-METHYL DC) is a modified nucleoside used in the synthesis of nucleoside phosphoramidites.
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7-10 days
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5'-O-DMT-N4-Ac-dC
5'-O-DMT-N4-Ac-dC
T37147100898-63-3
5'-O-DMT-N4-Ac-dC (N4-Acetyl-2'-deoxy-5'-O-DMT-cytidine, compound 7) is a deoxynucleoside used in synthesizing dodecyl phosphoramidite, a crucial precursor for dod-DNA production. Dod-DNA is amphiphilic DNA with dodecyl phosphotriester linkages, featuring an internal hydrophobic region[1][2].
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7-10 days
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