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lorvotuzumab
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Catalog No. T77406 Copy Product Info
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Lorvotuzumab (Anti-NCAM1/CD56 Reference Antibody (lorvotuzumab)) is a humanized monoclonal antibody that binds to CD56 (NCAM1) and can be used to synthesize the antibody-drug conjugate Lorvotuzumab mertansine.
Cas No. 339306-30-8
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| Pack Size | Price | USA Stock | Global Stock | Quantity |
|---|---|---|---|---|
| 1 mg | $313 | - | In Stock | |
| 5 mg | $793 | - | In Stock | |
| 10 mg | $1,290 | - | In Stock | |
| 25 mg | $1,890 | - | In Stock | |
| 50 mg | $2,580 | - | In Stock |
For In stock only · Estimated delivery: USA Stock (1-2 days) Global Stock (5-7 days)
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For research use only—not for human use. No sales to individuals. Use as intended only.
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Purity:> 95%
Appearance:Liquid
Color:Transparent
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Product Introduction
Bioactivity
Related Conjugates and Formulations
Antigen Details
Chemical Properties
Antibody Information
Storage & Solubility Information
| Description | Lorvotuzumab (Anti-NCAM1/CD56 Reference Antibody (lorvotuzumab)) is a humanized monoclonal antibody that binds to CD56 (NCAM1) and can be used to synthesize the antibody-drug conjugate Lorvotuzumab mertansine. |
| In vivo | Lorvotuzumab mertansine (IMGN901) is an antibody-drug conjugate (ADC) that utilizes a disulfide linker to connect the potent anti-mitotic agent DM1 to the CD56-targeting antibody (Lorvotuzumab). Lorvotuzumab mertansine is effective against Wilms' tumor, rhabdomyosarcoma, and neuroblastoma. |
| Endotoxin | <1.0 EU/mg |
| Reactivity | Human |
| Verified Activity | Immobilized Human NCAM1 Protein (His) (TMPY-00480) at 1 μg/mL (100 μL/well) can bind lorvotuzumab. The EC50 is 9.8 ng/mL.  |
| Application | Functional assay |
| Antibody Type | Monoclonal |
| Formulation | Supplied as a sterile solution in a buffered formulation system (e.g., phosphate-, citrate-, or amino acid-based). Please refer to the CoA for lot-specific composition. |
| Endotoxin | <1.0 EU/mg |
| Conjucates | Unconjugated |
| Gene ID | |
| Uniprot ID | |
| Target | NCAM1/CD56 |
| Molecular Weight | 146.44 kDa |
| Cas No. | 339306-30-8 |
| Isotype | Human IgG1 kappa |
| Recommended Isotype Control |
| Storage | Store at low temperature -20°C for 1 year Shipping with blue ice/Shipping at ambient temperature. |
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Please see Inhibitor Handling Instructions for more frequently ask questions. Topics include: how to prepare stock solutions, how to store products, and cautions on cell-based assays & animal experiments, etc
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Related Tags: lorvotuzumab chemical structure | lorvotuzumab in vivo | lorvotuzumab molecular weight
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