adc antibody

Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab has been clinically used to treat HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastric Cancer.

Sacituzumab is a humanized IgG1 monoclonal antibody utilized in the synthesis of antibody-active small-molecule couplings (naked antibody to Sacituzumab govitecan). It exhibits potential antitumor activity and is employed in tumor research.

Enfortumab is a monoclonal antibody against Nectin-4.Enfortumab can be used to synthesize antibody-drug couplings (enfortumab vedotin) and can also be used in conjunction with platinum compounds to study uroepithelial cancers.

Brentuximab, a chimeric antibody targeting CD30, is a naked antibody to Brentuximab vedotin. It possesses antitumor activity and may be used to study relapsed or refractory Hodgkin's lymphoma.

Turmetabart is an IgG1 monoclonal antibody targeting SEZ6, which can be used for the synthesis of antibody-drug conjugates (ADCs), such as ABBV-011.

Moxetumomab is a monoclonal antibody targeting CD22, which can be used to synthesise the antibody-drug conjugate (ADC) Moxetumomab pasudotox for the study of hairy cell leukaemia (HCL).

Inebilizumab is a humanized anti-CD19 monoclonal antibody with enhanced antibody-dependent cell-mediated cytotoxicity against B cells. Inebilizumab can be used to treat a range of autoimmune diseases associated with CD19 B cells, such as multiple sclerosis and optic neuromyelitis.

Camidanlumab (HuMax-TAC) is a humanised monoclonal antibody against CD25/IL-2Rα, commonly utilised in the synthesis of the ADC molecule Camidanlumab tesirine.

Pivekimab is a high-affinity humanised monoclonal antibody targeting CD123 (IL-3RA), which can be used to synthesise the ADC molecule pivekimab sunirine, for the study of acute myeloid leukaemia and blast plasmacytoid dendritic cell neoplasm (BPDCN).

Inotuzumab (Humanized Anti-CD22 Recombinant Antibody) is a humanized IgG4 antibody targeting CD22. This naked antibody can be used to synthesize antibody-active molecule conjugators [Inotuzumab ozogamicin] and to study acute lymphoblastic leukemia and non-Hodgkin's lymphoma.

Denintuzumab (hBU 12) is a humanized monoclonal antibody targeting CD19, used in the synthesis of ADC compound Denintuzumab Mafodotin and in the study of acute lymphoblastic leukemia.

Lonigutamab (hz208F2-4) is a humanized monoclonal antibody targeting the insulin-like growth factor-1 receptor (IGF-1R) for the study of thyroid eye disease.

Praluzatamab is a monoclonal antibody targeting an activated white blood cell adhesion molecule (ALCAM/CD116). It is a naked antibody used to synthesize antibody active molecule conjugates (Praluzatamab ravtansine) and can be employed to study breast cancer.

Belantamab (GSK2857914) is a humanized IgG1 monoclonal antibody against BCMA (TNFRSF17). Belantamab is a naked antibody to Belantamab mafodotin and can be used to synthesize antibody-active molecule conjugates (Belantamab mafodotin).

Disitamab Vedotin (RC48-0) is a humanized monoclonal antibody that targets HER2 and can be utilized in creating antibody-drug conjugates (ADCs), specifically referred to as Disitamab Vedotin [1].

Tisotumab (Anti-Human F3 Recombinant Antibody) is a human IgG1 monoclonal antibody targeting tissue factor (TF), utilized in antibody-conjugating drugs for cancer research.

Lorvotuzumab (Anti-NCAM1/CD56 Reference Antibody (lorvotuzumab)) is a humanized monoclonal antibody that binds to CD56 (NCAM1) and can be used to synthesize the antibody-drug conjugate Lorvotuzumab mertansine.

Lupartumab (BAY 1112623) is a monoclonal antibody targeting LYPD3 (C4.4A) and is employed in the synthesis of antibody-active molecular couplers for studying LYPD3-associated tumor diseases.

LadiratuzumAb (hLIV22) is a humanized monoclonal antibody targeting LIV-1/ZIP6.LadiratuzumAb is a naked antibody to SGN-LIV1A and is capable of synthesizing an antibody-activated molecule coupling (ADC), SGN-LIV1A.LadiratuzumAb can be used for the prevention and treatment of breast cancer.

Glembatumumab is a fully human IgG2 monoclonal antibody targeting the extracellular structural domain of GPNMB expressed in human breast cancer and melanoma. It is a naked antibody to Glembatumumab vedotin and can be used to study antibody-activated molecule couplings (Glembatumumab vedotin).

Tamrintamab (SC-003 mAb) is an antibody targeting dipeptidase 3 (DPEP3), a potential cytotoxic agent for ovarian cancer research.

Polatuzumab is a monoclonal antibody that targets CD79b and carries chemotherapeutically active molecules.Polatuzumab adheres to CD79b proteins and transports the chemotherapeutically active molecules into cells to kill them.Polatuzumab can be used to synthesize the antibody-compound coupling, Polatuzumab Vedotin.

Upifitamab is a naked antibody to upifitamab rilsodotin, which can be used to synthesize the antibody-coupled active molecule UPRI, which can be used to study cancer.

Ozuriftamab (BA302) is a human immunoglobulin IgG1 kappa monoclonal antibody specifically designed to target the receptor tyrosine kinase-like orphan receptor 2 (ROR2), and this antibody serves as the foundational targeting moiety for the synthesis of antibody-drug conjugates (ADCs), such as Ozuriftamab vedotin.