TN3541 |
Broussonin E
|
90902-21-9
|
98%
|
|
Broussonin E could suppress inflammation by modulating macrophages activation state via inhibiting the ERK and p38 MAPK and enhancing JAK2-STAT3 signaling pathwa...
|
T14330 |
Ascochlorin
|
26166-39-2
|
98%
|
|
Ascochlorin (Ilicicolin D), an isoprenoid antibiotic, mediates its anti-tumor effects predominantly through the suppression of STAT3 signaling cascade. Ascochlor...
|
TN1013 |
Cucurbitacin D
|
3877-86-9
|
98%
|
|
Cucurbitacin D has anticancer effects, it induces apoptosis through caspase-3 and phosphorylation of JNK in hepatocellular carcinoma cells.
|
T4571 |
Balsalazide
|
80573-04-2
|
98%
|
|
Balsalazide is an anti-inflammatory compound used in the treatment of Inflammatory Bowel Disease.
|
T11449L |
Golotimod
|
229305-39-9
|
98%
|
|
Golotimod is an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and spl...
|
TN4490 |
Manassantin B
|
88497-88-5
|
98%
|
|
Manassantin B is a potent inhibitor of NF-κB activation by the suppression of transciptional activity of RelA/p65 subunit of NF-κB. It also possesses anti-EBV ...
|
TN4604 |
Myricanone
|
32492-74-3
|
98%
|
|
Myricanone has antioxidant, and anticancer activities, it has apoptosis-promoting ability by triggering caspase activation, and suppression of cell proliferation...
|
TN2775 |
2-Methoxystypandrone
|
85122-21-0
|
98%
|
|
2-Methoxystypandrone displays an immunomodulatory effect in a cellular model, it blocks inflammatory responses by impairing NF-κB signaling to limit the inflamm...
|
TN4356 |
Jolkinolide A
|
37905-07-0
|
98%
|
|
Jolkinolide A has anti-tumor activity. It inhibited VEGF expression in A549 cells through the inhibition of the Akt-STAT3-mTOR signaling pathway, and directly in...
|
TN1631 |
Eupalinolide K
|
108657-10-9
|
98%
|
|
Eupalinolide K is a natural product
|
T15234 |
ENMD-1198
|
864668-87-1
|
98%
|
|
ENMD-119 is a 2-methoxyestradiol analog with antiproliferative and antiangiogenic activity. It is suitable for inhibiting HIF-1α and STAT3 in human HCC cells.
|
TN4489 |
Manassantin A
|
88497-87-4
|
98%
|
|
Manassantin A is a high potent HIF-1 inhibitor, it protects the gastric mucosa from ethanol-induced acute gastric injury, and suggest that these protective effec...
|
T11449 |
Golotimod hydrochloride (229305-39-9 free base)
|
T11449
|
98%
|
|
Golotimod hydrochloride (SCV 07 hydrochloride), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis...
|
TMA1743 |
Ergosterol peroxide
|
2061-64-5
|
98%
|
|
Ergosterol peroxide is an inhibitor of osteoclast differentiation, which has antiviral, trypanocidal, antitumor, and antiangiogenic actions, it can stimulate Fox...
|
TN1775 |
Isocryptotanshinone
|
22550-15-8
|
98%
|
|
Isocryptotanshinone inhibits protein tyrosine phosphatase 1B (PTP1B) activity with 50% inhibitory concentration values of 56.1±6.3 μM, PTP1B acts as a negative r...
|
T12905 |
SI-109
|
T12905
|
98%
|
|
SI-109 is a potent inhibitor of STAT3 SH2 domain (Ki=9 nM),and with antitumor activity.
|
TN4774 |
Physalin A
|
23027-91-0
|
98%
|
|
Physalin A exerts anti-tumor activity in non-small cell lung cancer cell lines by suppressing JAK/STAT3 signaling, it inhibits androgen-independent prostate canc...
|
T11449L2 |
Golotimod (TFA) (229305-39-9 free base)
|
T11449L2
|
98%
|
|
Golotimod (TFA), an immunomodulating peptide with antimicrobial activity, significantly increases the efficacy of antituberculosis therapy, stimulates thymic and...
|
TN2511 |
Britannilactone diacetate
|
1286694-67-4
|
98%
|
|
1,6-O,O-Diacetylbritannilactone(OODBL) has anti-inflammatory activity, it has a potential therapeutic efficacy on inflammatory diseases especially allergic airwa...
|
TN3525 |
Boehmenan
|
57296-22-7
|
98%
|
|
(±)-Boehmenan shows potent protein-tyrosine phosphatase 1B (PTP1B) inhibitory activity in vitro with the IC(50) values of 43.5 uM, it inhibits PTP1B activity in ...
|