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Search Results for " caspase "

Targets

296

Compounds

115

Natural Products

98

Recombinant Proteins

2

Libraries

Cat No. Product Name Synonyms Targets
T6005 Z-DEVD-FMK Caspase-3 Inhibitor Caspase
Z-DEVD-FMK (Caspase-3 Inhibitor) is a selective, irreversible Caspase-3 inhibitor, and also exhibits effective inhibition activity on caspase-6, caspase-7, caspase-8, and caspase-10.
T11696 Ivachtin Caspase-3 Inhibitor VII Caspase
Ivachtin (Caspase-3 Inhibitor VII) is a nonpeptide, noncompetitive and reversibl caspase-3 inhibitor(IC50 = 23 nM) and is a modest inhibitor of the remaining caspases.
T21871 MMPSI Caspase-3/7 Inhibitor I Apoptosis , Caspase
MMPSI (Caspase-3/7 Inhibitor I) is a novel, non-peptide small molecule caspase 3 and caspase 7 inhibitor that reduces ischemic injury in isolated rabbit heart or cardiomyocytes and inhibits apoptosis of H16c2 cells in a ...
T7019 Z-IETD-FMK Z-IE(OMe)TD(OMe)-FMK,Caspase-8 Inhibitor Caspase
Z-IETD-FMK (Z-IE(OMe)TD(OMe)-FMK) is a selective caspase 8 inhibitor, which has cell permeable.
T70650 Caspase-6-IN-1
Caspase-6-IN-1 is a novel Allosteric Inhibitor of Caspase-6 Activation, blocking the interaction between C6 and mHTT1-586.
T7020 Z-VAD-FMK Z-VAD(OH)-FMK,Caspase Inhibitor VI,Z-VAD Caspase
Z-VAD-FMK (Caspase Inhibitor VI) is a broad-spectrum inhibitor of caspases with irreversible properties. Z-VAD-FMK binds to activated caspases, thereby inhibiting apoptosis.
T72281 Caspase-9 Inhibitor III Ac-LEHD-cmk
Caspase-9 Inhibitor III (Ac-LEHD-cmk) is a caspase-9 inhibitor. Caspase-9 Inhibitor III exhibits protective effects on ischemia-reperfusion-induced myocardial injury .
T36347 Ac-YVAD-CMK Caspase-1 Inhibitor II,Ac-Tyr-Val-Ala-Asp-chloromethylketone,Ac-Tyr-Val-Ala-Asp-CMK IL Receptor , Caspase , Immunology/Inflammation related , Pyroptosis
Ac-YVAD-CMK (Ac-Tyr-Val-Ala-Asp-CMK) is a selective and irreversible inhibitor of Caspase-1 and inhibits pyroptosis, IL-1β and IL-18. Ac-YVAD-CMK shows neuroprotective and anti-inflammatory capacity.
T63479 Caspase-3-IN-1
Caspase-3-IN-1 is a potent inhibitor of Caspase-3 (IC50: 14.5 nM).
T82774 Caspase-3 activator 3 Caspase
Caspase-3 activator 3 (compound 2h) effectively induces apoptosis in HL-60 and K562 cells by substantially activating caspase-3, demonstrating antileukemic activity with IC50 values of 42.89 μM and 33.61 μM, respectively...
T76571 Caspase-8-IN-1
Caspase-8-IN-1 is a potent caspase-8 inhibitor [1] .
T82775 Caspase-3 activator 2 Caspase
Caspase-3 Activator 2 (Compound 2f) is a caspase 3 activator with cytotoxic effects on HL-60 and K562 cells, exhibiting IC 50 values of 33.52 μM and 76.90 μM, respectively [1]. It facilitates apoptosis, rendering it usef...
T79743 Caspase-3 activator 1 Pyroptosis
Caspase-3 activator 1 (compound 4b), a Ru(III) metal complex, effectively inhibits gastric tumor growth and metastasis by mediating caspase-3 cleavage. This cleavage enables Caspase-3 to process gasdermin E (GSDME), whic...
T72316 Caspase-3/7 activator 3
Caspase-3/7 activator 3 is an effective activator of Caspase-3/7 . Caspase-3/7 activator 3 has tumor selectivity, anti-proliferative activity and high Apoptosis -inducing ability .
T72315 Caspase-3/7 activator 2
Caspase-3/7 activator 2 is an effective activator of Caspase-3/7 . Caspase-3/7 activator 2 has tumor selectivity, anti-proliferative activity and high Apoptosis -inducing ability .
T83963 Z-DEVD-FMK Caspase-3 Inhibitor
Z-DEVD-FMK, a Caspase-3 Inhibitor, is an irreversible, cell-permeable inhibitor of caspase-3/CPP32 that impedes tumor cell apoptosis. In vivo studies show it offers neuroprotection in rat hippocampi post-seizures and con...
TP1466 Z-YVAD-FMK Caspase
AA-Z-YVAD-FMK is a Irreversible caspase-1 inhibitor,with anti-inflammatory and anti-tumor activities.
TQ0146L Ac-DEVD-CHO acetate Caspase-3 Inhibitor I,N-acetyl-asp-glu-val-asp-al,Ac-DEVD-CHO acetate (169332-60-9 free base) Caspase
Caspase-3 Inhibitor I (N-acetyl-asp-glu-val-asp-al) is a specific inhibitor of Caspase-3.
T7374 2-HBA Caspase , NADPH
2-HBA, a synthetic analog of curcumin, is an indirect inducer of enzymes that catalyze detoxification reactions through the Keap1-Nrf2-ARE pathway.
T10580 BOC-D-FMK Apoptosis , Caspase
Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 µM).
T10384 Farudodstat ASLAN003 Apoptosis , Dehydrogenase , DNA/RNA Synthesis
Farudodstat (ASLAN003) is an orally active and potent inhibitor of DHODH (Human Dihydroorotate Dehydrogenase) with antitumor activity. It has the potential to be a first-in-class candidate in AML.
T1724 SCR7 pyrazine SCR7 Apoptosis , DNA/RNA Synthesis , CRISPR/Cas9
SCR7 pyrazine (SCR7) enhances CRISPR-Cas9-mediated homology-directed repair (HDR) efficiency in vitro up to 19-fold. Inhibits nonhomologous end-joining (NHEJ).
T6090 Belnacasan VX-765 Caspase
Belnacasan (VX-765) is an orally active IL-converting enzyme/caspase-1 inhibitor.
T3103 L67 DNA Ligase Inhibitor DNA , DNA/RNA Synthesis
L67 (DNA Ligase Inhibitor) is a competitive human DNA ligase inhibitor, inhibits DNA ligases I and III (IC50: 10 μM).
T9118 KEA1-97 Apoptosis , Others , Caspase
Kea1-97 is a selective disruptor of interaction between thioredoxin and caspase-3 (IC50 = 10 μ M). Kea1-97 destroys the interaction between thioredoxin and caspase 3 and activates caspases without affecting the activity ...
T16104 ML-9 Myosin , Akt
ML-9 suppresses MLCK, PKA, and PKC activity with Ki values of 4, 32, and 54 μM, respectively. ML-9 is a selective and effective inhibitor of Akt kinase, inhibits myosin light-chain kinase (MLCK), and stromal interaction ...
T6993 Tauroursodeoxycholate sodium Sodium tauroursodeoxycholate,Tauroursodeoxycholic acid sodium salt,TUDC,Sodium Tauroursodeoxycholate (TUDC) Apoptosis , ERK , Caspase
Tauroursodeoxycholate sodium (TUDC) is an endoplasmic reticulum (ER) stress inhibitor, used for the treatment of gallstones and liver cirrhosis.
T22119 NS3694 Apoptosis
NS3694 is an inhibitor of apoptosis and inhibits apoptosome formation and caspase activation.
T1979 AVN-944 VX-944 Dehydrogenase
AVN-944 (VX-944)(VX-944) is a selective, noncompetitive inhibitor of human IMPDH with Ki of 6-10 nM for IMPDH1/IMPDH2.
T0432 Diclofenac diethylamine Apoptosis , COX
Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).
T0300 Pargyline Pargylamine,Paragyline MAO , Monoamine Oxidase
Pargyline (Pargylamine) is a monoamine oxidase inhibitor with antihypertensive properties.
T2065 Bioymifi DR5 Activator Apoptosis , TNF
Bioymifi (DR5 Activator) is a novel and potent small-molecule activator of the TRAIL receptor DR5 in human cancer cells.
T6738 Z-FA-FMK SARS-CoV , Cysteine Protease
Z-FA-FMK can irreversibly inhibit cysteine protease and also inhibit effector caspases.
T17011 TCH-165 Proteasome
TCH-165 is a small molecule modulator of proteasome assembly, resulting in an increase in 20S levels. The increase in the level of free 20S corresponds to enhanced proteolysis of IDPs.
T6258 Zibotentan ZD4054 Apoptosis , Endothelin Receptor
Zibotentan (ZD4054) (ZD4054) is a specific Endothelin (ET)A antagonist with IC50 of 21 nM, exhibiting no activity at ETB. Phase 3.
T0282 Q-VD-OPH Quinoline-Val-Asp-Difluorophenoxymethylketone Caspase , HIV Protease
Q-VD-OPH (Quinoline-Val-Asp-Difluorophenoxymethylketone) is a pan-caspase inhibitor with potent antiapoptotic properties.
T5104 BTSA1 Apoptosis , BCL
BTSA1 is a BAX activator that binds with high affinity and specificity to the N-terminal activation site and induces conformational changes to BAX leading to BAX-mediated apoptosis.
T8478 SC-43 Apoptosis , Phosphatase , STAT
SC-43 is a potent and orally active agonist of SHP-1 (PTPN6). SC-43 inhibits the phosphorylation of STAT3 and induces cell apoptosis, and with anti-fibrotic and anticancer effects.
T15771 Lobaplatin D-19466 DNA Alkylation
Lobaplatin (D-19466) (D-19466) is a diastereometric mixture of platinum(II) complexe. Lobaplatin (D-19466) is a third-generation platinum anti-neoplastic agent which shows activity for a variety of tumour types and is a ...
T1578 Pargyline hydrochloride Pargylamine hydrochloride MAO , Monoamine Oxidase
Pargyline hydrochloride (Pargylamine hydrochloride) is an irreversible monoamine oxidase(MAO) inhibitor with antihypertensive properties.
T16522 Phenoxodiol Dehydroequol,Idronoxil,Haginin E Apoptosis , IAP , Caspase , Topoisomerase , p53
Phenoxodiol (Idronoxil) activates the mitochondrial caspase system, inhibits X-linked inhibitor of apoptosis(XIAP), disrupts FLICE inhibitory protein(FLIP) expression, and sensitizes the cancer cells to Fas-mediated apop...
T6761 Ossirene AS101 IL Receptor , Caspase , Interleukin
Ossirene (AS101), a potent in vitro and in vivo immunomodulator, is a novel inhibitor of IL-1beta converting enzyme.
T1266 Terfenadine (±)-Terfenadine,MDL-991 Apoptosis , Potassium Channel , 5-HT Receptor , Caspase , Na+/Ca2+ Exchanger , HER , AChR , Histamine Receptor
Terfenadine ((±)-Terfenadine) is a prodrug that is metabolized by intestinal CYP3A4 to the active form fexofenadine, a selective histamine H1-receptor antagonist with antihistaminic and non-sedative effects.
T11793 KY-05009 Wnt/beta-catenin
KY-05009 pharmacologically inhibits TGF-β1-induced epithelial-to-mesenchymal transition (EMT) in human lung adenocarcinoma cells. KY-05009 inhibits the protein expression of TNIK and transcriptional activity of Wnt targe...
T0196 Diclofenac Diclofenacum,Voltaren Apoptosis , COX
Diclofenac (Diclofenacum) is a nonsteroidal benzeneacetic acid derivative with anti-inflammatory activity. Diclofenac binds and chelates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of a...
T2085 PQ401 IGF-1R Inhibitor II Apoptosis , IGF-1R
PQ401 (IGF-1R Inhibitor II) suppresses autophosphorylation of IGF-1R domain(IC50<1 μM).
T0859 Fenbufen CL-82204,Lederfen ATPase , Caspase , COX
Fenbufen (Lederfen) is a non-steroidal anti-inflammatory drug used primarily to treat inflammation in osteoarthritis, ankylosing spondylitis, and tendinitis. It can also be used to relieve backaches, sprains, and fractur...
T2503 PAC-1 Procaspase activating compound 1 Apoptosis , Caspase , Autophagy
PAC-1 (Procaspase activating compound 1) has been used in trials studying the treatment of Lymphoma, Melanoma, Solid Tumors, Breast Cancer, and Thoracic Cancers, among others.
T6826 Emricasan PF 03491390,IDN-6556 Influenza Virus , Caspase
Emricasan (IDN-6556) is an effective and irreversible pan-caspase inhibitor.
T38562 AKN-028 FLT
AKN-028 is an orally active and potent FLT3 tyrosine kinase inhibitor ( IC 50 = 6 nM). AKN-028 causes dose-dependent inhibition of FLT3 autophosphorylation.

Compounds

Z-DEVD-FMK
T6005
Synonym: Caspase-3 Inhibitor
Target: Caspase
Ivachtin
T11696
Synonym: Caspase-3 Inhibitor VII
Target: Caspase
MMPSI
T21871
Synonym: Caspase-3/7 Inhibitor I
Target: Apoptosis, Caspase
Z-IETD-FMK
T7019
Synonym: Z-IE(OMe)TD(OMe)-FMK,Caspase-8 Inhibitor
Target: Caspase
Caspase-6-IN-1
T70650
Synonym:
Target:
Z-VAD-FMK
T7020
Synonym: Z-VAD(OH)-FMK,Caspase Inhibitor VI,Z-VAD
Target: Caspase
Caspase-9 Inhibitor III
T72281
Synonym: Ac-LEHD-cmk
Target:
Ac-YVAD-CMK
T36347
Synonym: Caspase-1 Inhibitor II,Ac-Tyr-Val-Ala-Asp-chloromethylketone,Ac-Tyr-Val-Ala-Asp-CMK
Target: IL Receptor, Caspase, Immunology/Inflammation related, Pyroptosis
Caspase-3-IN-1
T63479
Synonym:
Target:
Caspase-3 activator 3
T82774
Synonym:
Target: Caspase
Caspase-8-IN-1
T76571
Synonym:
Target:
Caspase-3 activator 2
T82775
Synonym:
Target: Caspase
Caspase-3 activator 1
T79743
Synonym:
Target: Pyroptosis
Caspase-3/7 activator 3
T72316
Synonym:
Target:
Caspase-3/7 activator 2
T72315
Synonym:
Target:
Z-DEVD-FMK Caspase-3 Inhibitor
T83963
Synonym:
Target:
Z-YVAD-FMK
TP1466
Synonym:
Target: Caspase
Ac-DEVD-CHO acetate
TQ0146L
Synonym: Caspase-3 Inhibitor I,N-acetyl-asp-glu-val-asp-al,Ac-DEVD-CHO acetate (169332-60-9 free base)
Target: Caspase
2-HBA
T7374
Synonym:
Target: Caspase, NADPH
BOC-D-FMK
T10580
Synonym:
Target: Apoptosis, Caspase
Farudodstat
T10384
Synonym: ASLAN003
Target: Apoptosis, Dehydrogenase, DNA/RNA Synthesis
SCR7 pyrazine
T1724
Synonym: SCR7
Target: Apoptosis, DNA/RNA Synthesis, CRISPR/Cas9
Belnacasan
T6090
Synonym: VX-765
Target: Caspase
L67
T3103
Synonym: DNA Ligase Inhibitor
Target: DNA, DNA/RNA Synthesis
KEA1-97
T9118
Synonym:
Target: Apoptosis, Others, Caspase
ML-9
T16104
Synonym:
Target: Myosin, Akt
Tauroursodeoxycholate sodium
T6993
Synonym: Sodium tauroursodeoxycholate,Tauroursodeoxycholic acid sodium salt,TUDC,Sodium Tauroursodeoxycholate (TUDC)
Target: Apoptosis, ERK, Caspase
NS3694
T22119
Synonym:
Target: Apoptosis
AVN-944
T1979
Synonym: VX-944
Target: Dehydrogenase
Diclofenac diethylamine
T0432
Synonym:
Target: Apoptosis, COX
Pargyline
T0300
Synonym: Pargylamine,Paragyline
Target: MAO, Monoamine Oxidase
Bioymifi
T2065
Synonym: DR5 Activator
Target: Apoptosis, TNF
Z-FA-FMK
T6738
Synonym:
Target: SARS-CoV, Cysteine Protease
TCH-165
T17011
Synonym:
Target: Proteasome
Zibotentan
T6258
Synonym: ZD4054
Target: Apoptosis, Endothelin Receptor
Q-VD-OPH
T0282
Synonym: Quinoline-Val-Asp-Difluorophenoxymethylketone
Target: Caspase, HIV Protease
BTSA1
T5104
Synonym:
Target: Apoptosis, BCL
SC-43
T8478
Synonym:
Target: Apoptosis, Phosphatase, STAT
Lobaplatin
T15771
Synonym: D-19466
Target: DNA Alkylation
Pargyline hydrochloride
T1578
Synonym: Pargylamine hydrochloride
Target: MAO, Monoamine Oxidase
Phenoxodiol
T16522
Synonym: Dehydroequol,Idronoxil,Haginin E
Target: Apoptosis, IAP, Caspase, Topoisomerase, p53
Ossirene
T6761
Synonym: AS101
Target: IL Receptor, Caspase, Interleukin
Terfenadine
T1266
Synonym: (±)-Terfenadine,MDL-991
Target: Apoptosis, Potassium Channel, 5-HT Receptor, Caspase, Na+/Ca2+ Exchanger, HER, AChR, Histamine Receptor
KY-05009
T11793
Synonym:
Target: Wnt/beta-catenin
Diclofenac
T0196
Synonym: Diclofenacum,Voltaren
Target: Apoptosis, COX
PQ401
T2085
Synonym: IGF-1R Inhibitor II
Target: Apoptosis, IGF-1R
Fenbufen
T0859
Synonym: CL-82204,Lederfen
Target: ATPase, Caspase, COX
PAC-1
T2503
Synonym: Procaspase activating compound 1
Target: Apoptosis, Caspase, Autophagy
Emricasan
T6826
Synonym: PF 03491390,IDN-6556
Target: Influenza Virus, Caspase
AKN-028
T38562
Synonym:
Target: FLT
1 2 3 4 5 6
Cat No. Product Name Synonyms Targets
T5S2076 Senkyunolide I Others , Caspase
1. Senkyunolide I has neuroprotective effect, associated with its anti-oxidation and anti-apoptosis properties.
T5S2283 Sesamolin p38 MAPK , Caspase , JNK
1. Sesamolin and Sesamin has neuroprotective effect. 2. Sesamolin protects microglia against H2O2-induced cell injury, by inhibiting of p38 MAPK and caspase-3 activation and ROS production. 3. Sesamolin and Sesamin can s...
T13815 Penicillic acid Apoptosis , Caspase , Antibacterial , Antibiotic
Penicillic acid, a polyketide mycotoxin, synthesized by various species of Aspergillus and Penicillium, acts as an inhibitor of Fas ligand-induced apoptosis by impeding self-processing of caspase-8. Additionally, in vitr...
T2532 Tauroursodeoxycholate Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA Apoptosis , ERK , P450 , Caspase , Endogenous Metabolite
Tauroursodeoxycholate (UR 906), also known as ursodoxicoltaurine, is a highly hydrophilic tertiary bile acid that is produced in humans at a low concentration. Tauroursodeoxycholate is the more hydrophilic form of ursode...
T9503 PHYTOSPHINGOSINE Apoptosis
Phytosphingosine is a phospholipid with anticancer properties. In cancer cells, Phytosphingosine induces cell apoptosis through activation of caspase 8 and translocation of Bax.
T7982 3,6-Dihydroxyflavone Others
3,6-Dihydroxyflavone suppresses the epithelial-mesenchymal transition in breast cancer cells by inhibiting the Notch signaling pathway.
T2A2481 Taurochenodeoxycholic Acid Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine Apoptosis , TNF , Caspase , Endogenous Metabolite
Taurochenodeoxycholic Acid (12-Deoxycholyltaurine) is one of the main bioactive substances of animals' bile acid.
TN2215 Taurochenodeoxycholic acid sodium Sodium taurochenodeoxycholate Apoptosis , Endogenous Metabolite
Taurochenodeoxycholic acid sodium (Sodium taurochenodeoxycholate) is one of the main bioactive substances of animals' bile acid. Taurochenodeoxycholic acid sodium induces apoptosis and shows obvious anti-inflammatory and...
T3S1227 Aristolactam I Aristolactam,Aristololactam I,Aristololactum Apoptosis , Caspase
1.Aristolactam I (Aristololactum) has cytotoxic potency, mediated through the induction of apoptosis in a caspase 3-dependent pathway. 2. The effects of Aristololactam I may be mediated by different mechanisms except TGF...
T2698 Asperosaponin VI Akebia saponin D,Asperosaponin Ⅵ Apoptosis , Others , Caspase
Asperosaponin VI (Akebia saponin D) , the most abundant constituent of the rhizome of Dipsacus asper, has been used for the treatment of lower back pain, traumatic hematoma and bone fractures.
T5A2461 Bufotalin Bufotaline Apoptosis , Others , Reactive Oxygen Species
1. Bufotalin (Bufotaline)e is a kind of poisonous secretions of toads.
T5S2358 Dehydrocorydaline Dehydrocorydalin,13-Methylpalmatine BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimeriz...
T21936 M50054 Caspase
Apoptosis Inhibitor was a novel inhibitor of programmed cell death associate with caspase-3 inhibition.
T3384 Wedelolactone IKK Inhibitor II Apoptosis , NF-κB , Lipoxygenase , Caspase
Wedelolactone (IKK Inhibitor II) inhibits NF-κB-mediated gene transcription in cells by blocking the phosphorylation and degradation of IκBα.
T5574 Guggulsterone Guggulsterone E&Z Apoptosis , FXR , Akt , Caspase , JNK , Autophagy
Guggulsterone (Guggulsterone E&Z) E&Z is a 3-hydroxy steroid. It has a role as an androgen.
T2S0500 Ilexsaponin A Ilexsaponin A1 Others
1. Ilexsaponin A (Ilexsaponin A1) shows protective effects on ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway.
TN1405 Arnicolide D Akt , Caspase , PI3K , STAT , mTOR
Arnicolide D is a sesquiterpene lactone. Arnicolide D isolates from Centipeda minima. Arnicolide D modulates the cell cycle, activates the caspase signaling pathway and inhibits the PI3K/AKT/mTOR and STAT3 signaling path...
T10990 Dehydrocorydaline chloride 13-Methylpalmatine chloride BCL , PARP , p38 MAPK , Caspase , Parasite , Autophagy
Dehydrocorydaline chloride (13-Methylpalmatine chloride) is an alkaloid with anti-inflammatory and anti-cancer activity. Can improve the activation of p38 MAPK.
T2S2362 Dehydrocorydaline nitrate BCL , Others , PARP , p38 MAPK , Caspase , Parasite , Autophagy
1. Dehydrocorydaline(DHC) not only inhibits antibody-mediated allergic reactions but also influences cell-mediated allergic reactions, and the inhibitory effect of Corydalis Tuber on allergic reactions may be partially a...
T1079 Metronidazole Flagyl,Metronidazol,Anagiardil Apoptosis , NADPH , Hydrogenase , Antibacterial , Antibiotic , Parasite , Antifection
Metronidazole (Metronidazol) is a synthetic nitroimidazole derivative with antiprotozoal and antibacterial activities.
T2764 (S)-10-Hydroxycamptothecin 10-Hydroxycamptothecin,10-HCPT Apoptosis , Topoisomerase
(S)-10-Hydroxycamptothecin (10-HCPT) is a DNA topoisomerase I inhibitor, utilized as a clinical therapy agent against hepatoma.
TJA2398 Taurodeoxycholic acid sodium hydrate Sodium taurodeoxycholate monohydrate,Taurodeoxychloic Acid sodium hydrate,Taurohyodeoxycholic acid sodium salt Apoptosis , Caspase
Taurodeoxycholic acid sodium hydrate (Sodium taurodeoxycholate monohydrate), a hydrophilic bile salt, on bile salt and biliary lipid secretion in the rat.
T2959 Ginsenoside Rh2 20(S)-Rh2,20S-Ginsenoside Rh2,20(S)-Ginsenoside Rh2 Apoptosis , EGFR , Caspase , Endogenous Metabolite
Ginsenoside Rh2 (20(S)-Ginsenoside Rh2), an extract of red Panax ginseng, is a potent anti-inflammatory and anticancer drug.
T5S1805 5,7-Dihydroxychromone 5,7-Dihydroxy-4H-Chromen-4-One Others , Virus Protease , PARP , Caspase , Nrf2
1. 5,7-Dihydroxychromone (5,7-Dihydroxy-4H-Chromen-4-One) isolated from DME is one of the active compounds that may contribute to regulate blood glucose levels. 2. 5,7-Dihydroxychromone exerts neuroprotective effect agai...
T1152 Albendazole SKF-62979 HIF/HIF Prolyl-Hydroxylase , Microtubule Associated , Antibiotic , Parasite
Albendazole (SKF-62979) is used as a drug indicated for the treatment of a variety of worm infestations.
T5558 Chelidonic acid Jervaic acid,Jerva acid,γ-Pyrone-2,6-dicarboxylic acid NF-κB , Caspase
Chelidonic acid (Jervaic acid) is a component of Chelidonium majus L., used as a mild analgesic, an antimicrobial, an acentral nervous system sedative. Chelidonic acid (Jervaic acid) also shows anti-inflammatory activity...
T7727 Se-Methylselenocysteine Se MSC,SeMCys,MSeC,Se-MSC,SeMSC BCL , IAP , Caspase
Se-Methylselenocysteine (Se-MSC) is a potent chemopreventive agent in many test systems and has been shown to inhibit tumor promotion and induce apoptosis.
T8296 5,​7,​4'-​Trimethoxyflavone 4',5,7-Trimethoxyflavone Apoptosis , PARP , Caspase
5,7,4'-Trimethoxyflavone (4',5,7-Trimethoxyflavone) is isolated from Kaempferia parviflora (KP) which is a medicinal plant from Thailand.
T2881 Crustecdysone Commisterone,B-ecdysone,Commisterone,20-Hydroxyecdysone,Ecdysterone,B-ecdysone,Hydroxyecdysone Others , Caspase , Endogenous Metabolite , Autophagy
Crustecdysone (Hydroxyecdysone) is a steroid hormone that regulates the processes of molting or ecdysis in insects.
T2163 Dihydrocapsaicin CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide Others , TRP/TRPV Channel
Dihydrocapsaicin (CCRIS1589) is isolated from Capsicum fruit. Capsaicin is the primary active component of the heat and pain-eliciting lipid soluble fraction of the Capsicum pepper. Like capsaicin, dihydrocapsaicin is an...
T2851 Daphnetin 7,8-Dihydroxycoumarin,Daphnetol EGFR , PKA , PKC , Parasite , Autophagy
Daphnetin (7,8-Dihydroxycoumarin), a natural coumarin derivative, is a protein kinase inhibitor with inhibitory for EGFR (IC50: 7.67 μM), PKA (IC50: 9.33 μM), and PKC (IC50: 25.01 μM), also exhibit anti-oxidant and anti-...
T4085 Paris saponin VII Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII Apoptosis , BCL , Others , PARP , p38 MAPK , Akt , Caspase , P-gp , Autophagy
Paris saponin VII (Dioscini) shows inhibitory effects on cell proliferation.
TN1086 Dehydrotrametenolic acid Dehydroeburicoic acid Apoptosis , TNF , NOS , Caspase , NO Synthase
Dehydrotrametenolic acid (Dehydroeburicoic acid) induces necrotic cell death that involves Ca(2+) overload, mitochondrial dysfunction, and calpain activation in human glioblastomas.
T5S2083 Puerarin 6''-O-Xyloside Apoptosis , Caspase
Puerarin 6''-O-xyloside possesses significant anti-osteoporotic activity on ovariectomy mice, it has significant antitumour activities, the mechanisms are related to increased levels of caspase-3, caspase-7, caspase-9 an...
T3914 Saikosaponin C Beta Amyloid , Caspase
Saikosaponin C efficiently inhibited LPS-induced apoptotic cell death via inhibition of caspase-3 activation and caspase-3-mediated-FAK degradation.
T8092 Taurohyodeoxycholic acid sodium salt Sodium taurohyodeoxycholate hydrate Caspase
Taurohyodeoxycholic acid sodium salt (Sodium taurohyodeoxycholate hydrate) prevents apoptosis by blocking a calcium-mediated apoptotic pathway as well as caspase-12 activation.
T3892 Isoacteoside Isoverbascoside NF-κB
Isoacteoside has the anti-inflammatory effect, mediated by action on caspase-1, mitogen-activated protein kinases (c-Jun N-terminal kinase, p38, extracellular signal-regulated protein kinase) and nuclear factor-kappa B p...
TN1880 Lucidenic acid B Lucidenicacid B Apoptosis , Caspase
Lucidenic acid B (Lucidenicacid B), a natural compound extracted from Ganoderma lucidum, induces activation of caspase-9 and caspase-3 and cleavage of PARP, which can induce apoptosis in human leukemia cells through mito...
T3857 Magnolin (+)-Magnolin ERK
Magnolin reduces the renal oxidative stress, suppresses caspase-3 activity, and increases Bcl-2 expression in vivo and in vitro. Magnolin has anti-inflammatory and antioxidative effects.
T16791 Rottlerin Mallotoxin,NSC 56346,NSC 94525 CaMK , Apoptosis , Others , HIV Protease , PKA , PKC , Autophagy
Rottlerin (NSC-56346) is a natural product purified from Mallotus Philippinensis and is a specific PKC inhibitor (IC50: PKCδ of 3-6 μM, PKCα,β,γ of 30-42 μM, PKCε,η,ζ of 80-100 μM). Rottlerin causes apoptosis via caspase...
T3240 Citronellol dihydrogeraniol,(±)-β-Citronellol Reactive Oxygen Species
Citronellol ((±)-β-Citronellol) is used in insect repellents and perfumes and as a mite attractant.
T4S1335 Daphnoretin Dephnoretin,Thymelol Influenza Virus , Caspase , PKC
1. Daphnoretin (Thymelol) has strong antiviral activity, mainly on the later phase of the replication cycle. 2. Daphnoretin has anticancer effects on leukemia, osteosarcoma and uterine cervix cancer cells, might through ...
T3771 Methyl protodioscin Smilax saponin B,NSC-698790 Apoptosis
Methyl protodioscin (Smilax saponin B) potentially increase HDL cholesterol while reducing LDL cholesterol and triglycerides. Methyl protodioscin has antitumor property. Methyl protodioscin induced apoptotic process in h...
T3S0335 Soyasaponin Bb Soyasaponin I NF-κB , Caspase
1. Soyasaponin Bb (Soyasaponin I) can suppress Eca-976 cell growth, reverse effects on over expression of c-met, VEGF, and induce cell apoptosis through inhibiting HDAC1-NF-kappaB and activating PETEN and caspase-3 signa...
T7452 2-methoxycinnamaldehyde O-methoxycinnamaldehyde Apoptosis , Others
2-methoxycinnamaldehyde is a natural compound of Cinnamomum cassia,has been widely studied with regard to its antitumor activity.
TN1711 Gossypetin Antioxidant , p38 MAPK , MAPK , Antibacterial
Gossypetin, a hexahydroxylated flavonoid extractable from Rhodiola rosea Linn. is a potent MKK3 and MKK6 inhibitor that strongly attenuates the MKK3/6-p38 signaling pathway.Gossypetin exhibits antimutagenic, antiatherosc...
TN1393 (-)-Anonaine Apoptosis , Antioxidant , Parasite , Antifungal
(-)-Anonaine can be extracted from several species of Magnoliaceae and Annelidae and has antimalarial, antibacterial, antifungal, antioxidant, anticancer, antidepressant and vasodilatory activities. (-)-Anonaine induces ...
T75319 Taurodeoxycholic acid Taurodeoxychloic acid Apoptosis , Calcium Channel , Caspase
Taurodeoxycholic acid (Taurodeoxychloic acid) is a bile acid taurine conjugate of deoxycholic acid, a human metabolite that stabilizes mitochondrial membranes and reduces the formation of free radicals.Taurodeoxycholic a...
T6S1597 Mulberroside A TNF , Tyrosinase , Interleukin
1. Mulberroside has nephroprotective, hypoglycemic, and antidiabetic effects. 2. Mulberroside A is a glycosylated stilbene of oxyresveratrol; thus, the deglycosylation of Mulberroside A resulted in enhanced inhibition of...
TN1620 Eriocalyxin B Apoptosis , cAMP , NF-κB , STAT
Eriocalyxin B induces apoptosis and cell cycle arrest in pancreatic adenocarcinoma cells through caspase- and p53-dependent pathways, should be considered a candidate for pancreatic cancer treatment; it is a specific inh...
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Natural Products

Senkyunolide I
T5S2076
Synonym:
Target: Others, Caspase
Sesamolin
T5S2283
Synonym:
Target: p38 MAPK, Caspase, JNK
Penicillic acid
T13815
Synonym:
Target: Apoptosis, Caspase, Antibacterial, Antibiotic
Tauroursodeoxycholate
T2532
Synonym: Taurolite,Tauroursodeoxycholic Acid,UR 906,Ursodeoxycholyltaurine,TUDCA
Target: Apoptosis, ERK, P450, Caspase, Endogenous Metabolite
PHYTOSPHINGOSINE
T9503
Synonym:
Target: Apoptosis
3,6-Dihydroxyflavone
T7982
Synonym:
Target: Others
Taurochenodeoxycholic Acid
T2A2481
Synonym: Chenodeoxycholyltaurine,TCDCA,Chenyltaurine,Taurochenodeoxycholate,12-Deoxycholyltaurine
Target: Apoptosis, TNF, Caspase, Endogenous Metabolite
Taurochenodeoxycholic acid sodium
TN2215
Synonym: Sodium taurochenodeoxycholate
Target: Apoptosis, Endogenous Metabolite
Aristolactam I
T3S1227
Synonym: Aristolactam,Aristololactam I,Aristololactum
Target: Apoptosis, Caspase
Asperosaponin VI
T2698
Synonym: Akebia saponin D,Asperosaponin Ⅵ
Target: Apoptosis, Others, Caspase
Bufotalin
T5A2461
Synonym: Bufotaline
Target: Apoptosis, Others, Reactive Oxygen Species
Dehydrocorydaline
T5S2358
Synonym: Dehydrocorydalin,13-Methylpalmatine
Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy
M50054
T21936
Synonym:
Target: Caspase
Wedelolactone
T3384
Synonym: IKK Inhibitor II
Target: Apoptosis, NF-κB, Lipoxygenase, Caspase
Guggulsterone
T5574
Synonym: Guggulsterone E&Z
Target: Apoptosis, FXR, Akt, Caspase, JNK, Autophagy
Ilexsaponin A
T2S0500
Synonym: Ilexsaponin A1
Target: Others
Arnicolide D
TN1405
Synonym:
Target: Akt, Caspase, PI3K, STAT, mTOR
Dehydrocorydaline chloride
T10990
Synonym: 13-Methylpalmatine chloride
Target: BCL, PARP, p38 MAPK, Caspase, Parasite, Autophagy
Dehydrocorydaline nitrate
T2S2362
Synonym:
Target: BCL, Others, PARP, p38 MAPK, Caspase, Parasite, Autophagy
Metronidazole
T1079
Synonym: Flagyl,Metronidazol,Anagiardil
Target: Apoptosis, NADPH, Hydrogenase, Antibacterial, Antibiotic, Parasite, Antifection
(S)-10-Hydroxycamptothecin
T2764
Synonym: 10-Hydroxycamptothecin,10-HCPT
Target: Apoptosis, Topoisomerase
Taurodeoxycholic acid sodium hydrate
TJA2398
Synonym: Sodium taurodeoxycholate monohydrate,Taurodeoxychloic Acid sodium hydrate,Taurohyodeoxycholic acid sodium salt
Target: Apoptosis, Caspase
Ginsenoside Rh2
T2959
Synonym: 20(S)-Rh2,20S-Ginsenoside Rh2,20(S)-Ginsenoside Rh2
Target: Apoptosis, EGFR, Caspase, Endogenous Metabolite
5,7-Dihydroxychromone
T5S1805
Synonym: 5,7-Dihydroxy-4H-Chromen-4-One
Target: Others, Virus Protease, PARP, Caspase, Nrf2
Albendazole
T1152
Synonym: SKF-62979
Target: HIF/HIF Prolyl-Hydroxylase, Microtubule Associated, Antibiotic, Parasite
Chelidonic acid
T5558
Synonym: Jervaic acid,Jerva acid,γ-Pyrone-2,6-dicarboxylic acid
Target: NF-κB, Caspase
Se-Methylselenocysteine
T7727
Synonym: Se MSC,SeMCys,MSeC,Se-MSC,SeMSC
Target: BCL, IAP, Caspase
5,​7,​4'-​Trimethoxyflavone
T8296
Synonym: 4',5,7-Trimethoxyflavone
Target: Apoptosis, PARP, Caspase
Crustecdysone
T2881
Synonym: Commisterone,B-ecdysone,Commisterone,20-Hydroxyecdysone,Ecdysterone,B-ecdysone,Hydroxyecdysone
Target: Others, Caspase, Endogenous Metabolite, Autophagy
Dihydrocapsaicin
T2163
Synonym: CCRIS1589,6,7-Dihydrocapsaicin,8-Methyl-N-vanillylnonanamide
Target: Others, TRP/TRPV Channel
Daphnetin
T2851
Synonym: 7,8-Dihydroxycoumarin,Daphnetol
Target: EGFR, PKA, PKC, Parasite, Autophagy
Paris saponin VII
T4085
Synonym: Chonglou Saponin VII,Polyphyllin-VII,Dioscinin,Paris saponin-VII
Target: Apoptosis, BCL, Others, PARP, p38 MAPK, Akt, Caspase, P-gp, Autophagy
Dehydrotrametenolic acid
TN1086
Synonym: Dehydroeburicoic acid
Target: Apoptosis, TNF, NOS, Caspase, NO Synthase
Puerarin 6''-O-Xyloside
T5S2083
Synonym:
Target: Apoptosis, Caspase
Saikosaponin C
T3914
Synonym:
Target: Beta Amyloid, Caspase
Taurohyodeoxycholic acid sodium salt
T8092
Synonym: Sodium taurohyodeoxycholate hydrate
Target: Caspase
Isoacteoside
T3892
Synonym: Isoverbascoside
Target: NF-κB
Lucidenic acid B
TN1880
Synonym: Lucidenicacid B
Target: Apoptosis, Caspase
magnolin
T3857
Synonym: (+)-Magnolin
Target: ERK
Rottlerin
T16791
Synonym: Mallotoxin,NSC 56346,NSC 94525
Target: CaMK, Apoptosis, Others, HIV Protease, PKA, PKC, Autophagy
Citronellol
T3240
Synonym: dihydrogeraniol,(±)-β-Citronellol
Target: Reactive Oxygen Species
Daphnoretin
T4S1335
Synonym: Dephnoretin,Thymelol
Target: Influenza Virus, Caspase, PKC
Methyl protodioscin
T3771
Synonym: Smilax saponin B,NSC-698790
Target: Apoptosis
Soyasaponin Bb
T3S0335
Synonym: Soyasaponin I
Target: NF-κB, Caspase
2-methoxycinnamaldehyde
T7452
Synonym: O-methoxycinnamaldehyde
Target: Apoptosis, Others
Gossypetin
TN1711
Synonym:
Target: Antioxidant, p38 MAPK, MAPK, Antibacterial
(-)-Anonaine
TN1393
Synonym:
Target: Apoptosis, Antioxidant, Parasite, Antifungal
Taurodeoxycholic acid
T75319
Synonym: Taurodeoxychloic acid
Target: Apoptosis, Calcium Channel, Caspase
Mulberroside A
T6S1597
Synonym:
Target: TNF, Tyrosinase, Interleukin
Eriocalyxin B
TN1620
Synonym:
Target: Apoptosis, cAMP, NF-κB, STAT

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01824 Caspase-14 Protein, Human, Recombinant (His) Human E. coli
Caspase 14 is a member of the caspase family. Caspases are a kind of cysteine proteinase consisting of a prodomain plus large and small catalytic subunits, that play a central role in cell apoptosis. Caspase 14 possesses...
TMPY-02831 Caspase-7 Protein, Human, Recombinant (His) Human E. coli
Caspase 7, also known as caspase-7 and MCH3, belongs to the cysteine-aspartic acid protease (caspase) family. Caspases play a role in the signal transduction pathways of apoptosis, necrosis and inflammation. There are tw...
TMPJ-01256 Caspase-10 Protein, Human, Recombinant (His) Human E. coli
Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granz...
TMPH-01056 Caspase-3 Protein, Human, Recombinant (His) Human E. coli
TMPH-01055 Caspase-1 Protein, Human, Recombinant (HA) Human E. coli
TMPH-01057 Caspase-8 Protein, Human, Recombinant (His) Human E. coli
TMPJ-01059 CRADD Protein, Human, Recombinant Human E. coli
Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues, with particularly high expression in the adult heart, testis, liver, skeletal muscle, fetal liver, and kidney. CRADD contains one CARD do...
TMPY-00817 Granzyme B/GZMB Protein, Human, Recombinant (His) Human HEK293
Granzyme B, also known as GZMB, is the most prominent member of the granzyme family of cell death-inducing serine proteases expressed in the granules of cytotoxic T lymphocytes (CTLs) and NK cells. Granzyme B enters the ...
TMPY-02078 HtrA2/Omi Protein, Human, Recombinant (His) Human E. coli
Serine protease HTRA2, also known as high-temperature requirement protein A2, Omi stress-regulated endoprotease, Serine protease 25, Serine proteinase OMI and HTRA2, is a single-pass membrane protein that belongs to the ...
TMPY-01928 IL-18 Protein, Rhesus, Recombinant (His) Rhesus E. coli
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-g...
TMPY-03273 IL-18 Protein, Mouse, Recombinant Mouse E. coli
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-g...
TMPY-00277 IL-18 Protein, Human, Recombinant Human E. coli
Interleukin-18 (IL-18, also known as interferon-gamma inducing factor) is a proinflammatory cytokine that belongs to the IL-1 superfamily and is produced by macrophages and other cells. This cytokine can induce the IFN-g...
TMPY-01289 DDR1 Protein, Human, Recombinant (His) Human HEK293
Discoidin domain receptor family, member 1 (DDR1), also known as or CD167a (cluster of differentiation 167a), and Mammary carcinoma kinase 10 (MCK10), belongs to a subfamily of tyrosine kinase receptors with an extracell...
TMPY-00382 Thioredoxin/TRX Protein, Mouse, Recombinant Mouse E. coli
Thioredoxin, also known as ATL-derived factor, Surface-associated sulphydryl protein, SASP and TXN, is a nucleus, cytoplasm and secreted protein that belongs to the thioredoxin family. Thioredoxins are proteins that act ...
TMPY-02700 BCL2 Protein, Human, Recombinant (His) Human E. coli
BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family a...
TMPY-02431 BCL-XL Protein, Human, Recombinant (His) Human E. coli
B-cell lymphoma-extra large (Bcl-xl) is a transmembrane molecule in the mitochondria. Bcl-xL (BCL2L1), belongs to the Bcl-2 family. Members of the bcl-2 family encode proteins that function either to promote or to inhibi...
TMPY-02213 RAIDD Protein, Human, Recombinant (His) Human E. coli
Death domain-containing protein CRADD, also known as Caspase and RIP adapter with death domain, RIP-associated protein with a death domain, CRADD and RAIDD, is a protein which is constitutively expressed in most tissu...
TMPJ-00697 NOL3 Protein, Human, Recombinant (GST) Human E. coli
Nucleolar Protein 3 is encoded by NOL3 gene; multiple transcript variants encoding different isoforms have been found for this gene. So far, Nucleolar protein 3 has show to have two Isoforms. Isoform 1 may be involved in...
TMPJ-00718 AIF Protein, Human, Recombinant (His) Human E. coli
Apoptosis-Inducing Factor 1, Mitochondrial (AIFM1) is a flavoprotein essential for nuclear disassembly in apoptotic cells that is found in the mitochondrial intermembrane space in healthy cells. During apoptosis, it is t...
TMPJ-00358 DR6 Protein, Mouse, Recombinant (hFc & His) Mouse Human Cells
Tumor necrosis factor receptor superfamily member 21(DR6) is a single-pass type I membrane protein and contains 1 death domain and 4 TNFR-Cys repeats. The protein may activate NF-kappa-B and promote apoptosis and it may ...
TMPK-00277 TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc) Human HEK293
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter mol...
TMPH-01274 ZNRF3 Protein, Human, Recombinant (His & SUMO) Human E. coli
Abundant protease in the cytosolic granules of cytotoxic T-cells and NK-cells which activates caspase-independent pyroptosis when delivered into the target cell through the immunological synapse. It cleaves after Asp. On...
TMPY-02027 BID Protein, Human, Recombinant Human E. coli
The BH3 interacting domain death agonist (BID) is a pro-apoptotic member of the Bcl-2 protein family, which contains only the BH3 domain, and is required for its interaction with the Bcl-2 family proteins and for its pro...
TMPY-02065 BID Protein, Mouse, Recombinant (His & GST) Mouse E. coli
The BH3 interacting domain death agonist (BID) is a pro-apoptotic member of the Bcl-2 protein family, which contains only the BH3 domain, and is required for its interaction with the Bcl-2 family proteins and for its pro...
TMPJ-00215 Fas/CD95 Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Mouse Apoptosis-mediating surface antigen FAS (Fas) belongs to the death receptor subfamily of the TNF receptor superfamily and is designated TNFRSF6. Mouse Fas contains 1 death domain and 3 TNFR-Cys repeats. It detected...
TMPJ-00246 TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (hFc) Mouse Human Cells
Mouse tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) is a member of the TNFR family which contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10B exhibits high structural and functional homology to T...
TMPJ-00696 NOL3 Protein, Human, Recombinant Human E. coli
Nucleolar protein 3 is encoded by NOL3 gene. Multiple transcript variants encoding different isoforms have been found for this gene. So far, Nucleolar protein 3 has show to have two Isoforms. Isoform 1 may be involved in...
TMPJ-00245 TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (Avi & His), Biotinylated Mouse Human Cells
Mouse tumor necrosis factor receptor superfamily member 10B (TNFRSF10B) is a member of the TNFR family which contains 1 death domain and 3 TNFR-Cys repeats. TNFRSF10B exhibits high structural and functional homology to T...
TMPY-02922 XIAP Protein, Human, Recombinant (His) Human E. coli
E3 ubiquitin-protein ligase XIAP / BIRC4, also known as an inhibitor of apoptosis protein 3, X-linked inhibitor of apoptosis protein, and IAP-like protein, is a protein that belongs to a family of apoptotic suppressor pr...
TMPH-00021 Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His) Acinetobacter baumannii Yeast
Functions as a porin. Induces apoptosis in human cell lines through caspase-dependent and AIF-dependent pathways. Purified Omp38 enters host cell and localizes to the mitochondria, which presumably leads to a release of ...
TMPY-00507 UNC5B Protein, Human, Recombinant (hFc) Human HEK293
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPY-04003 UNC5B Protein, Rat, Recombinant (hFc) Rat HEK293
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPY-01216 XIAP Protein, Human, Recombinant (Avi) Human E. coli
E3 ubiquitin-protein ligase XIAP / BIRC4, also known as an inhibitor of apoptosis protein 3, X-linked inhibitor of apoptosis protein, and IAP-like protein, is a protein that belongs to a family of apoptotic suppressor pr...
TMPY-04133 UNC5B Protein, Human, Recombinant (His) Human HEK293
The netrin-1 receptor, UNC-5 Homology B, or UNC5B plays vital roles in angiogenesis, inflammation, embryonic development and carcinogenesis. Overexpression of UNC5B human colon epithelial cells suppressed dextran sodium ...
TMPY-01775 AIM2 Protein, Human, Recombinant (GST) Human Baculovirus-Insect Cells
AIM2, Absent In Melanoma 2 is a member of the interferon-inducible HIN-200 protein family that contains an amino-terminal pyrin domain and a carboxy-terminal oligonucleotide/oligosaccharide-binding domain, senses cytopla...
TMPK-00555 CDH17 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00473 CDH17 Protein, Rhesus macaque, Recombinant (His) Rhesus macaque HEK293
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-01224 CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated Mouse HEK293
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00952 CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc) Human HEK293
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPY-03572 PTRH2 Protein, Human, Recombinant (His) Human E. coli
PTH2, also known as PTRH2, is a mitochondrial protein that belongs to the PTH2 family. PTH 2 is released during apoptosis from the mitochondria to the cytoplasm. The natural substrate for PTH 2 may be peptidyl-tRNAs whic...
TMPK-00948 CDH17 Protein, Human, Recombinant (hFc) Human HEK293
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00162 IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated Human E. coli
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1...
TMPK-00950 CDH17 Domain 6-7 Protein, Human, Recombinant (hFc) Human HEK293
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00947 CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00951 CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated Human HEK293
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00515 IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His) Cynomolgus E. coli
Interleukin-1 beta (IL-1β) is induced by inflammatory signals in a broad number of immune cell types. IL-1β (and IL-18) are the only cytokines which are processed by caspase-1 after inflammasome-mediated activation. IL-1...
TMPK-00276 TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (His & Avi) Human HEK293
DR5, also called TRAIL R2, TRICK 2, TNFRSF10B, and MK is a type 1 TNF R superfamily, membrane protein which is a receptor for TRAIL (APO2 ligand). DR5 is a receptor for the cytotoxic ligand TNFSF10/TRAIL. The resulting d...
TMPK-00949 CDH17 Domain 7 Protein, Human, Recombinant (hFc) Human HEK293
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-00953 CDH17 Domain 6-7 Protein, Human, Recombinant (mFc) Human HEK293
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
TMPK-01223 CDH17 Protein, Mouse, Recombinant (His) Mouse HEK293
Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating...
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Caspase-14 Protein, Human, Recombinant (His)
TMPY-01824
Species: Human
Expression System: E. coli
Caspase-7 Protein, Human, Recombinant (His)
TMPY-02831
Species: Human
Expression System: E. coli
Caspase-10 Protein, Human, Recombinant (His)
TMPJ-01256
Species: Human
Expression System: E. coli
Caspase-3 Protein, Human, Recombinant (His)
TMPH-01056
Species: Human
Expression System: E. coli
Caspase-1 Protein, Human, Recombinant (HA)
TMPH-01055
Species: Human
Expression System: E. coli
Caspase-8 Protein, Human, Recombinant (His)
TMPH-01057
Species: Human
Expression System: E. coli
CRADD Protein, Human, Recombinant
TMPJ-01059
Species: Human
Expression System: E. coli
Granzyme B/GZMB Protein, Human, Recombinant (His)
TMPY-00817
Species: Human
Expression System: HEK293
HtrA2/Omi Protein, Human, Recombinant (His)
TMPY-02078
Species: Human
Expression System: E. coli
IL-18 Protein, Rhesus, Recombinant (His)
TMPY-01928
Species: Rhesus
Expression System: E. coli
IL-18 Protein, Mouse, Recombinant
TMPY-03273
Species: Mouse
Expression System: E. coli
IL-18 Protein, Human, Recombinant
TMPY-00277
Species: Human
Expression System: E. coli
DDR1 Protein, Human, Recombinant (His)
TMPY-01289
Species: Human
Expression System: HEK293
Thioredoxin/TRX Protein, Mouse, Recombinant
TMPY-00382
Species: Mouse
Expression System: E. coli
BCL2 Protein, Human, Recombinant (His)
TMPY-02700
Species: Human
Expression System: E. coli
BCL-XL Protein, Human, Recombinant (His)
TMPY-02431
Species: Human
Expression System: E. coli
RAIDD Protein, Human, Recombinant (His)
TMPY-02213
Species: Human
Expression System: E. coli
NOL3 Protein, Human, Recombinant (GST)
TMPJ-00697
Species: Human
Expression System: E. coli
AIF Protein, Human, Recombinant (His)
TMPJ-00718
Species: Human
Expression System: E. coli
DR6 Protein, Mouse, Recombinant (hFc & His)
TMPJ-00358
Species: Mouse
Expression System: Human Cells
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (hFc)
TMPK-00277
Species: Human
Expression System: HEK293
ZNRF3 Protein, Human, Recombinant (His & SUMO)
TMPH-01274
Species: Human
Expression System: E. coli
BID Protein, Human, Recombinant
TMPY-02027
Species: Human
Expression System: E. coli
BID Protein, Mouse, Recombinant (His & GST)
TMPY-02065
Species: Mouse
Expression System: E. coli
Fas/CD95 Protein, Mouse, Recombinant (hFc)
TMPJ-00215
Species: Mouse
Expression System: Human Cells
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (hFc)
TMPJ-00246
Species: Mouse
Expression System: Human Cells
NOL3 Protein, Human, Recombinant
TMPJ-00696
Species: Human
Expression System: E. coli
TRAIL R2/DR5/TNFRSF10B Protein, Mouse, Recombinant (Avi & His), Biotinylated
TMPJ-00245
Species: Mouse
Expression System: Human Cells
XIAP Protein, Human, Recombinant (His)
TMPY-02922
Species: Human
Expression System: E. coli
Outer membrane protein Omp38, Acinetobacter baumannii, Recombinant (His)
TMPH-00021
Species: Acinetobacter baumannii
Expression System: Yeast
UNC5B Protein, Human, Recombinant (hFc)
TMPY-00507
Species: Human
Expression System: HEK293
UNC5B Protein, Rat, Recombinant (hFc)
TMPY-04003
Species: Rat
Expression System: HEK293
XIAP Protein, Human, Recombinant (Avi)
TMPY-01216
Species: Human
Expression System: E. coli
UNC5B Protein, Human, Recombinant (His)
TMPY-04133
Species: Human
Expression System: HEK293
AIM2 Protein, Human, Recombinant (GST)
TMPY-01775
Species: Human
Expression System: Baculovirus-Insect Cells
CDH17 Protein, Cynomolgus, Recombinant (His)
TMPK-00555
Species: Cynomolgus
Expression System: HEK293
CDH17 Protein, Rhesus macaque, Recombinant (His)
TMPK-00473
Species: Rhesus macaque
Expression System: HEK293
CDH17 Protein (Primary Amine Labeling), Mouse, Recombinant (His), Biotinylated
TMPK-01224
Species: Mouse
Expression System: HEK293
CDH17 Domain 3 & 4 Protein, Human, Recombinant (mFc)
TMPK-00952
Species: Human
Expression System: HEK293
PTRH2 Protein, Human, Recombinant (His)
TMPY-03572
Species: Human
Expression System: E. coli
CDH17 Protein, Human, Recombinant (hFc)
TMPK-00948
Species: Human
Expression System: HEK293
IL-1 beta/IL-1F2 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00162
Species: Human
Expression System: E. coli
CDH17 Domain 6-7 Protein, Human, Recombinant (hFc)
TMPK-00950
Species: Human
Expression System: HEK293
CDH17 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00947
Species: Human
Expression System: HEK293
CDH17 Domain 5-7 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TMPK-00951
Species: Human
Expression System: HEK293
IL-1 beta/IL-1F2 Protein, Cynomolgus, Recombinant (His)
TMPK-00515
Species: Cynomolgus
Expression System: E. coli
TRAIL R2/DR5/TNFRSF10B Protein, Human, Recombinant (His & Avi)
TMPK-00276
Species: Human
Expression System: HEK293
CDH17 Domain 7 Protein, Human, Recombinant (hFc)
TMPK-00949
Species: Human
Expression System: HEK293
CDH17 Domain 6-7 Protein, Human, Recombinant (mFc)
TMPK-00953
Species: Human
Expression System: HEK293
CDH17 Protein, Mouse, Recombinant (His)
TMPK-01223
Species: Mouse
Expression System: HEK293
Cat No. Product Name
L8720 Pyroptosis Compound Library

1077 compounds
1077 types of active small molecules associated with pyroptosis for high-throughput and high-content screening.
L9700 Endoplasmic Reticulum Stress Compound Library

193 compounds
A unique collection of 193 endoplasmic reticulum stress (ER stress) related compounds used for high throughput screening (HTS) and high content screening (HCS);
TargetMol