13cd3

Alogliptin-13CD3 is the deuterium-labeled Alogliptin. Alogliptin (T6192) is a selective inhibitor of DPP-4.

Apixaban 13C,D3 is a deuterium labeling of Apixaban (T1736) for isotopic tracing. Apixaban 13C,D3 is a selective inhibitor of coagulation factor Xa and is used in thromboembolism studies

PSI-6206 13C,D3 is the deuterium labeled PSI-6206. PSI-6206 (T2117) is a potent and selective HCV NS5B polymerase inhibitor.

Tiopronin-13C,D3 is deuterium labeled Tiopronin (T1630).

4-Acetyl-N-methylaniline-13C-D3 is an isotopically labeled version of 4-Acetyl-N-methylaniline, featuring both 13C and tritium (D3) markers. Compounds marked with stable or radioactive isotopes are utilized in metabolic analysis to precisely trace and quantify the movement of individual atoms.

Methylcobalamin-13C-D3 the 13C and deuterated compound of Methylcobalamin (T3136). Methylcobalamin has a CAS number of 13422-55-4. Methylcobalamin is one active form of vitamin B12 which can directly participate in homocysteine metabolism. It is used to treat some nutritional diseases and other diseases in clinic, such as Alzheimer's disease and rheumatoid arthritis.

Rifampicin-13C-D3 the 13C and deuterated compound of Rifampicin (T0681). Rifampicin has a CAS number of 13292-46-1. Rifampicin is an antibacterial drug of the class of rifamycin.

Tadalafil-13C-D3 is a carboline-based compound with vasodilatory activity. Tadalafil (T1398) selectively inhibits the cyclic guanosine monophosphate (cGMP)-specific type 5 phosphodiesterase- (PDE-5)-mediated degradation of cGMP, which is found in the smooth muscle of the corpus cavernosa and corpus spongiosum of the penis. Inhibition of cGMP degradation by tadalafil results in prolonged muscle relaxation, vasodilation, and blood engorgement of the corpus cavernosa, and, so, prolonged penile erection.

Sildenafil-13C-D3 the 13C and deuterated compound of Sildenafil. Sildenafil has a CAS number of 139755-83-2. Sildenafil is a phosphodiesterase type 5 (PDE5) inhibitor, used to treat erectile dysfunction and reduce symptoms of pulmonary arterial hypertension (PAH).

Moxifloxacin-13C-D3 is a fourth-generation fluoroquinolone that has been shown to be effective against Gram-positive, Gram-negative, and atypical strains, as well as multi-drug resistant Streptococcus pneumoniae.

(S)-Alogliptin Benzoate Salt-13C-D3 is the 13C and deuterated compound of (S)-Alogliptin Benzoate Salt.

13C-D3-AOH1996 is the 13C and deuterated compound of AOH1996. 13C-AOH1996 (T77520) has a CAS number of 2089314-64-5. AOH1996 is an orally active ligand for the replicasome component PCNA (proliferating cell nuclear antigen), targeting the transcription-replication conflict (TRC).AOH1996 interferes with the interaction of PCNA with its binding proteins, leading to DNA replication stress and apoptosis.AOH1996 causes proteasome-dependent rpb1 degradation and lethal DNA damage by stabilizing the interaction between PCNA and RNA polymerase II.AOH1996 acts synergistically with DNA damaging agents to inhibit tumor cell growth. AOH1996 inhibits tumor cell growth by stabilizing the interaction between PCNA and RNA polymerase II, leading to proteasome-dependent rpb1 degradation and lethal DNA damage.AOH1996 acts synergistically with DNA damaging agents.

Apalutamide-13C-D3 is a 13C and 2H-labeled version of Apalutamide. Apalutamide (T2339) is an efficient androgen receptor (AR) antagonist used in the study of prostate diseases.

Binimetinib-13C-D3 is an isotopically labelled compound of Binimetinib for use as a tracer.Binimetinib (ARRY-162) is a selective MEK1/2 inhibitor for the treatment of melanoma.

Binimetinib Isomer Impurity-13C-D3 is the 13C and deuterated compound of Binimetinib Isomer Impurity (T7990).

Prasugrel Metabolite Derivative-13C-D3 is the 13C and deuterated compound of Prasugrel Metabolite Derivative.

cis-Clopidogrel-MP-13C-D3 Derivative is-Clopidogrel-MP-13C-D3 Derivative is the 13C and deuterated compound of cis-Clopidogrel-MP Derivative (T38506).

Eluxadoline-13C-D3 is the 13C and deuterated compound of Eluxadoline. Eluxadoline (T68510) has a CAS number of 864825-13-8.

Erythromycin-13C-D3 is a 13C- and deuterated erythromycin that can be used to study the metabolic pathways of erythromycin in vivo.

Nintedanib-13C-D3 is the 13C and deuterated compound of Nintedanib. Nintedanib (T1777) has a CAS number of 656247-17-5. Nintedanib (T1777) is an inhibitor of the receptor tyrosine kinases VEGFR/FGFR/PDGFR (IC50s: 13-34/37-610/59/65 nM for VEGFR1-3, FGFR1-4, and PDGFRα/β, respectively).

Prucalopride-13C-D3 is the 13C and deuterated compound of Prucalopride. Prucalopride (T2542) has a CAS number of 179474-81-8. Prucalopride (T2542) is a selective, high-affinity 5-HT4A/4B receptor agonist (Ki: 2.5/8 nM). It has >290-fold selectivity for 5-HT4A/4B receptor than other 5-HT receptor subtypes.

Sofosbuvir-13C-D3 is the 13C and deuterated compound of Sofosbuvir. Sofosbuvir (T6676) has a CAS number of 1190307-88-0. Sofosbuvir (T6676) is a uridine monophosphate analog inhibitor of hepatitis C virus (HCV) polymerase NS5B that is used as an antiviral agent in the treatment of chronic hepatitis C.

Taltirelin-13C-D3 is the 13C and deuterated compound of Taltirelin. Taltirelin (T7590) has a CAS number of 103300-74-9. Taltirelin (T7590) is at thyrotropin-releasing hormone receptor (TRH-R) superagonist (IC50 of 910 nM and EC50 of 36 nM for stimulating an increase in cytosolic Ca2+ concentration (Ca2+ release))[1].

Trelagliptin-13C-D3 is the 13C and deuterated compound of Trelagliptin. Trelagliptin (T6237) has a CAS number of 865759-25-7. Trelagliptin (T6237) is a highly specific and long-acting DPP-4 inhibitor.