T cells are one of the important types of white blood cells of the immune system and play a central role in the adaptive immune response. T cells are born from hematopoietic stem cells, found in the bone marrow. Developing T cells then migrate to the thymus gland to develop (or mature).After migration to the thymus, the precursor cells mature into several distinct types of T cells. T cell differentiation also continues after they have left the thymus.CD4 and CD8 T cells are selected in the thymus, but undergo further differentiation in the periphery to specialized cells which have different functions. Groups of specific, differentiated T cell subtypes have a variety of important functions in controlling and shaping the immune response. One of these functions is immune-mediated cell death, and it is carried out by two major subtypes: CD8+ "killer" (cytotoxic) and CD4+ "helper" T cells. Regulatory T cells are yet another distinct population of T cells that provide the critical mechanism of tolerance, whereby immune cells are able to distinguish invading cells from "self".
Cat No. | product name / Synonyms | Species | Expression System |
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TMPJ-00089 | CD3 epsilon/CD3e Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD3 epsilon/CD3e Protein, Human, Recombinant (hFc & Avi), Biotinylated
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Human | Human Cells |
T-Cell Surface Glycoprotein CD3 ε Chain (CD3ε) is a single-pass type I membrane protein. CD3ε contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. ... | |||
TMPJ-00092 | CD8B Protein, Human, Recombinant (His)
CD8B Protein, Human, Recombinant (His)
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Human | Human Cells |
T-Cell Surface Glycoprotein CD8β Chain (CD8 Antigen) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell inter... | |||
TMPJ-00097 | NKG2D/CD314 Protein, Cynomolgus, Recombinant (hFc)
NKG2D/CD314 Protein, Cynomolgus, Recombinant (hFc)
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Cynomolgus | Human Cells |
NKG2-D type II integral membrane protein (NKG2D) is a type II transmembrane glycoprotein which belongs to the CD94/NKG2 family. NKG2D is expressed on natural kil... | |||
TMPJ-00099 | CD28 Protein, Mouse, Recombinant (hFc & His)
CD28 Protein, Mouse, Recombinant (hFc & His)
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Mouse | Human Cells |
T-cell-specific surface glycoprotein CD28, contains an Ig-like V-type domain. CD28 is one of the proteins expressed on T cells that provide co-stimulatory signal... | |||
TMPJ-00102 | CD28 Protein, Human/Cynomolgus, Recombinant (hFc & Avi), Biotinylated
CD28 Protein, Human/Cynomolgus, Recombinant (hFc & Avi), Biotinylated
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Human,Cynomolyus | Human Cells |
T-cell-specific surface glycoprotein CD28(CD28) is a single-pass typeI membrane protein which contains one Ig-likeV-type (immunoglobulin-like) domain. It belon... | |||
TMPJ-00107 | CTLA-4 Protein, Human, Recombinant (Flag)
CTLA-4 Protein, Human, Recombinant (Flag)
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Human | Human Cells |
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. Human or mouse CTLA4 cDNA enc... | |||
TMPJ-00108 | CTLA-4 Protein, Human, Recombinant (GST)
CTLA-4 Protein, Human, Recombinant (GST)
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Human | Human Cells |
Cytotoxic Tlymphocyte 4(CTLA-4,CD152), is a type I transmembrane T cell inhibitory molecule that is a member of the Ig superfamily. Human or mouse CTLA4 cDNA enc... | |||
TMPJ-00122 | NKG2D/CD314 Protein, Mouse, Recombinant (His)
NKG2D/CD314 Protein, Mouse, Recombinant (His)
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Mouse | Human Cells |
NKG2-D type II integral membrane protein (NKG2D) is a type II transmembrane glycoprotein which belongs to the CD94/NKG2 family. NKG2D is expressed on natural kil... | |||
TMPJ-00140 | 4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
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Cynomolgus | Human Cells |
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pas... | |||
TMPJ-00141 | 4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc)
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc)
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Cynomolgus | Human Cells |
Tumor necrosis factor receptor superfamily member 9(TNFRSF9), also known as CD137 and 4-1BB, is an inducible T cell surface protein belonging to the tumor necros... | |||
TMPJ-00142 | 4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His)
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His)
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Cynomolgus | Human Cells |
Tumor necrosis factor receptor superfamily member 9(TNFRSF9), also known as CD137 and 4-1BB, is an inducible T cell surface protein belonging to the tumor necros... | |||
TMPJ-00143 | 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (aa 24-186, His & Avi), Biotinylated
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (aa 24-186, His & Avi), Biotinylated
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Human | Human Cells |
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pas... | |||
TMPJ-00144 | 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His)
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His)
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Human | Human Cells |
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pas... | |||
TMPJ-00145 | 4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (hFc)
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (hFc)
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Mouse | Human Cells |
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte acti... | |||
TMPJ-00150 | CD40 Ligand Protein, Human, Recombinant (Mammalian)
CD40 Ligand Protein, Human, Recombinant (Mammalian)
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Human | Human Cells |
CD40 Ligand (CD40LG) is a type II transmembrane glycoprotein that belongs to the TNF superfamily. Like other TNF superfamily members, CD40LG exists as a trimer i... | |||
TMPJ-00151 | CD40 Ligand Protein, Human, Recombinant
CD40 Ligand Protein, Human, Recombinant
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Human | E. coli |
CD40 Ligand (CD40LG) is a type II transmembrane glycoprotein that belongs to the TNF superfamily. Like other TNF superfamily members, CD40LG exists as a trimer i... | |||
TMPJ-00152 | CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated
CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | Human Cells |
CD40 Ligand (CD40LG) is a type II transmembrane glycoprotein that belongs to the TNF superfamily. Like other TNF superfamily members, CD40LG exists as a trimer i... | |||
TMPJ-00153 | CD40 Ligand Protein, Human, Recombinant (His & Flag)
CD40 Ligand Protein, Human, Recombinant (His & Flag)
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Human | Human Cells |
CD40 Ligand (CD40LG) is a type II transmembrane glycoprotein that belongs to the TNF superfamily. Like other TNF superfamily members, CD40LG exists as a trimer i... | |||
TMPJ-00181 | PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated
PD-1 Protein, Human, Recombinant (His & Avi), Biotinylated
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Human | Human Cells |
Programmed cell death protein 1(PDCD1) is a single-pass type I membrane protein and contains 1 Ig-like V-type domain. PD-1 is a member of the extended CD28/CTLA-... | |||
TMPJ-00190 | CD38 Protein, Mouse, Recombinant (hFc)
CD38 Protein, Mouse, Recombinant (hFc)
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Mouse | Human Cells |
CD38, also called ADP-ribosyl cyclase, is a Type II integral membrane protein with 301 amino acids in length that belongs to the ADP-ribosyl cyclase family.It sy... |