T0037 |
Halazone
|
80-13-7
|
90%
|
|
Halazone (Pantocid) is fine white powder with an odor of chlorine. It has been widely used to disinfect drinking water.
|
TN3910 |
Ecdysone
|
3604-87-3
|
100%
|
|
Ecdysone is a major steroid hormone in insects and herbs. Ecdysone triggers mineralocorticoid receptor activation and induces cellular apoptosis. Ecdysone signal...
|
T6782 |
Benzocaine hydrochloride
|
23239-88-5
|
|
|
Benzocaine hydrochloride (Ethyl 4-aminobenzoate hydrochloride) is a surface anesthetic that acts by preventing transmission of impulses along nerve fibers and at...
|
T3029 |
Sparteine sulfate
|
299-39-8
|
|
|
Sparteine sulfate (Tocosimplex) is a class 1a antiarrhythmic agent and a sodium channel blocker. It can chelate the bivalents calcium and magnesium.
|
TN3042 |
4-Hydroxycinnamamide
|
194940-15-3
|
98%
|
|
4-Hydroxycinnamamide has antioxidant activity. 4-Hydroxycinnamamide derivatives are specific inhibitors of tyrosine-specific protein kinases.
|
T78060 |
ProTx II TFA
|
|
98%
|
|
ProTx-II TFA is a potent and highly selective Nav1.7 sodium channel blocker, exhibiting an IC50 of 0.3 nM and demonstrating at least 100-fold selectivity over ot...
|
T78955 |
Analgesic agent-2
|
|
98%
|
|
Analgesic Agent-2, a selective orally active inhibitor of the NaV1.8 channel, demonstrates an IC50 of 50.18 nM in HEK293 cells that stably express the human NaV1...
|
T79246 |
6-Iodoamiloride
|
60398-23-4
|
98%
|
|
6-Iodoamiloride is a potent inhibitor of acid-sensing ion channel 1 (ASIC1), exhibiting an IC50 value of 88 nM. It also effectively inhibits ASIC3-mediated curre...
|
T79280 |
Nav1.3 channel inhibitor 1
|
|
98%
|
|
Nav1.3 Channel Inhibitor 1 (Compound 15b) is a state-dependent inhibitor of the voltage-gated sodium channel Na v 1.3, with an IC50 value of 20 nM. It has the ab...
|
T79398 |
Ancistrotecine B
|
|
98%
|
|
Ancistrotecine B (Compound 2), a Nav1.7 channel inhibitor (IC50: 0.73 μM), has been shown to alleviate inflammatory pain in mice [1].
|
T79834 |
Aneratrigine
|
2097163-74-9
|
98%
|
|
Aneratrigine is a blocker of the sodium channel protein type 9 subunit alpha, utilized in research on neuropathic pain diseases [1].
|
T80039 |
ATX-II
|
60748-45-0
|
98%
|
|
ATX-II, an Na+ channel modulator toxin derived from the sea anemone (Anemonia sulcata), causes delayed inactivation of the Na+ channels and has been linked to pu...
|
T80042 |
GpTx-1
|
1661050-12-9
|
98%
|
|
GpTx-1 exhibits potent selectivity as a NaV1.7 antagonist, demonstrating an inhibition concentration (IC50) of 10 nM [1].
|
T80043 |
µ-Conotoxin-CnIIIC
|
936616-33-0
|
98%
|
|
μ-Conotoxin-CnIIIC, a 22-residue conopeptide derived from Conus consors, acts as a potent and persistent NaV1.4 channel blocker, exhibiting analgesic, anaestheti...
|
T80049 |
µ-Conotoxin GIIIB
|
140678-12-2
|
98%
|
|
μ-Conotoxin GIIIB, a 22-residue polypeptide derived from the venom of the piscivorous cone snail Conus geographus, serves as an inhibitor of the Na V 1.4 channel...
|
T80159 |
µ-Conotoxin KIIIA
|
884469-67-4
|
98%
|
|
μ-Conotoxin KIIIA, an analgesic compound derived from Conus kinoshitai, selectively inhibits mammalian neuronal voltage-gated sodium channels (VGSCs) (Nav1.2), o...
|
T80162 |
Aah II
|
|
98%
|
|
Aah II, a sodium channel modulator, is a toxin derived from the venom of the scorpion Androctonus australis [1] [2].
|
T80163 |
μ-Conotoxin PIIIA
|
184840-20-8
|
98%
|
|
μ-Conotoxin PIIIA, isolated from Conus purpurascens [1] [2], is a blocker of the sodium channel NaV 1.4.
|
T80168 |
Scorpion toxin Tf2
|
|
98%
|
|
Scorpion toxin Tf2, a β-scorpion toxin first identified in the venom of the Brazilian scorpion Tityus fasciolatus, acts as an activator of the neuronal voltage-g...
|
T80169 |
ProTx-III
|
|
98%
|
|
ProTx-III, a spider venom peptide derived from the Peruvian green velvet tarantula, functions as a selective and potent inhibitor of the voltage-gated sodium cha...
|