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Results for "

mtor

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    367
    TargetMol | Inhibitors_Agonists
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    7
    TargetMol | Compound_Libraries
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    TargetMol | Inhibitors_Agonists
mTOR inhibitor-3
T121231207358-59-5In house
mTOR inhibitor-3 is a selective mTOR inhibitor (Ki= 1.5 nM). mTOR inhibitor-3 inhibits mTORC1 and mTORC2 in cellular and in vivo experiments.
  • $55
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mTOR/HDAC-IN-1 HCl
mTOR HDAC-IN-1 HCl(2815286-02-1 Free base)
T63399L In house
mTOR HDAC-IN-1 HCl is a potent dual inhibitor of mTOR and HDAC with potential anti-inflammatory, anti-proliferative, autophagy and apoptosis-inducing effects for cancer research.
  • $195
In Stock
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mTOR inhibitor-8
mTOR-IN-8
T363162489196-70-3
mTOR inhibitor-8 is a potent mTOR inhibitor and autophagy inducer with antiviral and antitumor activity. mTOR inhibitor-8 inhibits the growth of A549 cells, which can be used to study non-small cell lung cancer.
  • $48
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PI3K/Akt/mTOR-IN-2
T605642757804-89-8In house
PI3K Akt mTOR-IN-2 is a potent PI3K AKT mTOR inhibitor with anticancer effects and selectivity for MDA-MB-231 cells (IC50 2.29 μM). It induces cell cycle arrest and apoptosis in cancer cells.
  • $33
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mTOR inhibitor 9f
T677011144075-42-2In house
mTOR inhibitor 9f is a selective mTOR inhibitor with IC50 of 1.25nM and 82nM for mTOR and PI3Kα, respectively.
  • $118
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TargetMol | Inhibitor Sale
mTOR inhibitor 9d
T677021144075-38-6In house
mTOR inhibitor 9d is a dual inhibitor of the protein kinases mTOR and PI3K with an mTOR IC50 value of 0.31 nm, and can be used for the treatment of leukemia, skin cancer, breast cancer, lung cancer and colon cancer.
  • $210
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mTOR inhibitor 9b
T677031144075-34-2In house
mTOR inhibitor 9b is an enzyme inhibitor of protein kinase mTOR he phosphatidylinositol 3-kinase PIK3CA with IC50s of 0.76 nm and 1.262 µM, respectively.mTOR inhibitor 9b possesses anticancer activity and can be used to study leukemia, skin, breast, lung and colon cancers.
  • $210
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TargetMol | Inhibitor Sale
mTOR inhibitor 9e
T677041144075-40-0In house
mTOR inhibitor 9e is a selective mTOR inhibitor with IC50 of 0.68nM and 1359nM for mTOR and PI3Kα, respectively.
  • $197
In Stock
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mTOR inhibitor 9c
T677061144075-36-4In house
mTOR inhibitor 9c is a selective mTOR inhibitor with IC50 of 0.7nM and 825nM for mTOR and PI3Kα, respectively.
  • $197
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Rapamycin
Sirolimus, NSC-2260804, AY 22989
T153753123-88-9
Rapamycin (AY 22989) is a natural product of macrolides, an mTOR inhibitor with specificity (HEK293 cells: IC50=0.1 nM). Rapamycin has immunosuppressive activity and induces autophagy.
  • $30
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TargetMol | Inhibitor Hot
AZD-8055
T18591009298-09-2
AZD8055 is an ATP-competitive mTOR inhibitor (IC50: 0.8 nM in MDA-MB-468 cells). It is ~1,000-fold selective for mTOR over all PI3K isoforms.
  • $36
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TargetMol | Inhibitor Hot
MHY1485
T1908326914-06-1
MHY1485 is an mTOR activator that is cell-permeable. MHY1485 inhibits autophagosome and lysosome fusion, leading to accumulation of LC3II proteins and increased autophagosomes, thereby inhibiting cellular autophagy.
  • $43
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TargetMol | Inhibitor Hot
Torin 1
T60451222998-36-8
Torin 1 is an effective inhibitor of mTORC1 2 with (IC50: 2 nM 10 nM); has 1000-fold selectivity for mTOR than PI3K.
  • $30
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TargetMol | Inhibitor Hot
wye-132
WYE-125132, WYE125132, WYE 125132
T63461144068-46-1In house
WYE-125132 (WYE-132 (WYE-125132)) is a highly potent, ATP-competitive mTOR inhibitor with IC50 of 0.19 nM; highly selective for mTOR versus PI3Ks or PI3K-related kinases hSMG1 and ATR.
  • $39
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GDC-0349
RG-7603
T65101207360-89-1In house
GDC-0349 (RG-7603) is a potent and selective ATP-competitive inhibitor of mTOR with Ki of 3.8 nM, 790-fold inhibitory effect against PI3Kα and other 266 kinases. Phase 1.
  • $33
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way-600
WAY600
T67301062159-35-6In house
WAY-600 is a potent, ATP-competitive, and selective inhibitor of mTOR with an IC50 of 9 nM; it blocks mTORC1 P-S6K(T389) and mTORC2 P-AKT(S473) but not P-AKT(T308), and is selective for mTOR over PI3Kα (>100-fold) and PI3Kγ (>500-fold).
  • $32
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hSMG-1 inhibitor 11j
T88841402452-15-6In house
hSMG-1 inhibitor 11j is a pyrimidine derivative. hSMG-1 inhibitor 11j is a potent and selective inhibitor of hSMG-1, IC50 = 0.11 nM. hSMG-1 inhibitor 11j exhibits >455-fold selectivity for hSMG-1 over mTOR (IC50=50 nM), PI3Kα γ (IC50=92 60 nM) and CDK1 CDK2 (IC50=32 7.1 μM). hSMG-1 inhibitor 11j can be used for the research of cancer.
  • $163 TargetMol
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L-Leucine
Leu, (S)-Leucine
T3O274961-90-5
L-Leucine ((S)-Leucine) is one of nine essential amino acids in humans (provided by food), L-Leucine is important for protein synthesis and many metabolic functions. L-Leucine contributes to regulation of blood-sugar levels; growth and repair of muscle and bone tissue; growth hormone production; and wound healing. L-Leucine also prevents breakdown of muscle proteins after trauma or severe stress and may be beneficial for individuals with phenylketonuria. L-Leucine is available in many foods and deficiency is rare.
  • $42
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(+)-Usnic acid
D-Usnic Acid, (+)-Usniacin
T63547562-61-0
(+)-Usnic acid (D-Usnic Acid) is a naturally occurring dibenzofuran derivative found in several lichen species.
  • $29
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Vistusertib
AZD2014
T19611009298-59-2
Vistusertib (AZD2014) is an orally bioavailable inhibitor of the mammalian target of rapamycin (mTOR) with potential antineoplastic activity.
  • $31
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TargetMol | Inhibitor Sale
ETP-46464
T20841345675-02-6
ETP-46464 is an effective and specific ATR inhibitor (IC50: 25 nM).
  • $34
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Dactolisib
NVP-BEZ235, BEZ235
T2235915019-65-7
Dactolisib (BEZ235) is an orally bioavailable inhibitor of PI3K and mTOR, with IC50 values of 4 nM for p110α, 5 nM for p110γ, 7 nM for p110δ, 75 nM for p110β, and 20.7 nM for mTOR.
  • $39
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PP121
T24151092788-83-4
PP-121 is a multi-targeted inhibitor of PDGFR (IC50: 2 nM), Hck (IC50: 8 nM), mTOR (IC50: 10 nM), VEGFR2(IC50: 12 nM), Src (IC50: 14 nM) and Abl (IC50: 18 nM) , also inhibits DNA-PK (IC50: 60 nM).
  • $51
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TargetMol | Inhibitor Sale
KU-55933
ATM Kinase Inhibitor
T2685587871-26-9
KU-55933 (ATM Kinase Inhibitor) is an ATM inhibitor (IC50=12.9 nM; Ki=2.2 nM) that is selective and ATP-competitive. KU-55933 induces apoptosis and has antitumor effects.
  • $43
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