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Search Result

Search Results for "mcf-7"

Compounds

Cat No. Product Name
TN1768 Iriflophenone Estrogen/progestogen Receptor , Estrogen Receptor/ERR
Iriflophenone 是从 Aquilaria sinensis 中分离得到，能诱导 MCF-7 和 T-47D 人乳腺癌细胞增殖。
T8724 6-Methoxydihydrosanguinarine Others
6-Methoxydihydrosanguinarine 是一种从M. cordata 果实中分离出的生物碱，它对 MCF-7 细胞系(IC50:0.61 μM)和 SF-268 细胞系(IC50:0.54 μM)具有强的细胞毒性。
T9541 CTB Epigenetic Reader Domain
CTB 是一种 p300 组蛋白乙酰转移酶的激活剂，可诱导 MCF-7 细胞凋亡。
T2085 PQ401 IGF-1R Inhibitor II IGF-1R , Apoptosis
PQ401 是一种IGF-IR 抑制剂。在 MCF-7 细胞中，它抑制 IGF-I 刺激的 IGF-IR 自磷酸化，可有效抑制 IGF-I 刺激的 MCF-7 细胞生长。它诱导 caspase 介导的细胞凋亡，有用于乳腺癌和其他对 IGF-...
T6010 Idarubicin hydrochloride 盐酸伊达比星,伊达比星盐酸盐,Zavedos,Idarubicin HCl,4-demethoxydaunorubicin (NSC256439, 4-DMDR) HCl,Idamycin,4-Demethoxydaunorubicin hydrochloride Autophagy , Antibacterial , Topoisomerase , Antifungal
Idarubicin HCl 是一种蒽环类抗白血病药物，能抑制细菌和酵母菌生长，还抑制拓扑异构酶 II，干扰 DNA 复制和 RNA 转录。
T5724 Neogambogic acid 新藤黄酸,neo-gambogic acid Antibacterial , Apoptosis , Others
neo-gambogic acid 是藤黄的有效成分，可诱导细胞凋亡并具有抗癌作用。它有效抑制耐甲氧西林的金黄色葡萄球菌。
T12581 Puerarin-4'-O-β-D-glucopyranoside Puerarin4'-O-glucoside,葛根素-4'-Β-D-葡萄糖苷 Others
Puerarin-4'-O-β-D-glucopyranoside 是一种从葛根 (PLR) 中提取的异黄酮。它具有雌激素活性和抗 MCF-7 人乳腺癌细胞增殖作用。
T9244 σ1 Receptor antagonist-1 Sigma receptor
σ1 Receptor antagonist-1 是高选择性的 sigma 1受体拮抗剂，pKi 为10.28。它抑制细胞生长，在 G0/G1 期阻滞细胞周期并诱导 MCF-7/ADR 细胞凋亡。
T11929 M2N12 Phosphatase
M2N12 是一种高度选择性的细胞分裂周期蛋白磷酸酶 25C 抑制剂，IC50值为 0.09 μM。它还抑制 Cdc25A 和 Cdc25B 的活性，IC50值分别为 0.53 μM 和 1.39 μM。它具有抗肿瘤活性，可研究癌症。
T1933 NVP 231 ERK , Apoptosis
NVP 231 是一种强效、特异、可逆的神经酰胺激酶抑制剂，IC50值为12 nM，可竞争性地抑制神经酰胺与 CerK 的结合。它通过增加 DNA 片段和 caspase-3 和 caspase-9 的裂解来诱导细胞凋亡。
T9119 SU0268 Others
SU0268 是有效的 8-8-氧鸟嘌呤 DNA 糖基化酶1的选择性抑制剂，具有调控铜绿假单胞杆菌感染免疫反应的能力。
TN7060 Methyl oleanonate PPAR
Methyl oleanonate 是从柃木中分离得到的一种三萜类天然产物，是齐墩果酸衍生物，是一种PPARγ激动剂，具有抗癌作用。
T0308 Etidronic acid HEDP,HEDPA,Etidronate,羟乙磷酸 Apoptosis , Phosphatase , Others , HBV
Etidronate 是一种影响钙代谢的二膦酸盐，抑制异位钙化并减缓骨吸收和骨转换，可应用于洗涤，水处理，化妆品和制药业。
T9973 WAY-311677 FAK
WAY-311677 有潜在的抗增殖活性，是一种 FAK 抑制剂。
T8954 ML179 ML-179 Others
ML179 是一种有效的选择性肝受体同源物 1 (LRH1, NR5A2) 反向激动剂，IC50 为 320 nM。
TN7059 Deoxylimonin 脱氧柠檬苦素,NSC 314317,desoxylimonin Others
Desoxylimonin 是一种分离自葡萄柚籽中的三萜化合物。它是一种母体衍生物，其抗癌、缓解疼痛和抗炎活性比母体化合物强。
T8973 HS-1793 Others
HS-1793 是 resveratrol 类似物，可以诱导细胞凋亡，在多种癌细胞中有抗肿瘤的能力。
T22288 (1E)-CFI-400437 dihydrochloride CFI-400437 dihydrochloride PLK
(1E)-CFI-400437 dihydrochloride 是一种选择性和有效的 polo 样激酶 4 (PLK4) 抑制剂，IC50为 0.6 nM。它还抑制 Aurora A、 Aurora B、 KDR 和 FLT-3，IC5...
T41248 Thiocolchicine Microtubule Associated
Thiocolchicine 是一种有效的微管蛋白聚合抑制剂，IC50 为 2.5 µM，Ki 为 0.7 µM。 Thiocolchicine 诱导细胞凋亡。 Thiocolchicine 可用作 ADC 技术中的 ADC 细胞毒素。
T1166 Ellipticine Elliptisine,NSC 71795,玫瑰树碱 Topoisomerase
Ellipticine 是一种有效的抗肿瘤剂，抑制 DNA 拓扑异构酶 II 活性，对白血病、神经母细胞瘤和胶质母细胞瘤有部分活性。
Iriflophenone
TN1768
synonym:
Target:
6-Methoxydihydrosanguinarine
T8724
synonym:
Target:
CTB
T9541
synonym:
Target:
PQ401
T2085
synonym: IGF-1R Inhibitor II
Target:
Idarubicin hydrochloride
T6010
synonym: 盐酸伊达比星,伊达比星盐酸盐,Zavedos,Idarubicin HCl,4-demethoxydaunorubicin (NSC256439, 4-DMDR) HCl,Idamycin,4-Demethoxydaunorubicin hydrochloride
Target:
Neogambogic acid
T5724
synonym: 新藤黄酸,neo-gambogic acid
Target:
Puerarin-4'-O-β-D-glucopyranoside
T12581
synonym: Puerarin4'-O-glucoside,葛根素-4'-Β-D-葡萄糖苷
Target:
σ1 Receptor antagonist-1
T9244
synonym:
Target:
M2N12
T11929
synonym:
Target:
NVP 231
T1933
synonym:
Target:
SU0268
T9119
synonym:
Target:
Methyl oleanonate
TN7060
synonym:
Target:
Etidronic acid
T0308
synonym: HEDP,HEDPA,Etidronate,羟乙磷酸
Target:
WAY-311677
T9973
synonym:
Target:
ML179
T8954
synonym: ML-179
Target:
Deoxylimonin
TN7059
synonym: 脱氧柠檬苦素,NSC 314317,desoxylimonin
Target:
HS-1793
T8973
synonym:
Target:
(1E)-CFI-400437 dihydrochloride
T22288
synonym: CFI-400437 dihydrochloride
Target:
Thiocolchicine
T41248
synonym:
Target:
Ellipticine
T1166
synonym: Elliptisine,NSC 71795,玫瑰树碱
Target:
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