level — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T5S0246	Pseudoprotodioscin		Others , Fatty Acid Synthase
	1. Pseudoprotodioscin has moderate cytotoxicity.		Others , Fatty Acid Synthase
T8869	B355252		Others
	B355252 protects against cell death caused by glutamate-evoked oxidative stress. B355252 shows neuroprotective effect, potentiating nerve growth factor (NGF)-induced neurite outgrowth.		Others
T14943	CGP60474		VEGFR , CDK , PKC
	CGP60474 is an inhibitor of VEGFR-2 (IC50 = 84 nM) and an inhibitor of ATP-competitive PKC. CGP60474 is also a highly potent anti-endotoxemic agent and inhibits cyclin-dependent kinase (CDK) potently.		VEGFR , CDK , PKC
T11660	Insulin levels modulator		COX
	Insulin level regulators can be used to treat diabetes.		COX
T67767	HIF-1 inhibitor-4	HIF-1 inhibitor-4	HIF
	HIF-1 inhibitor-4 (HIF-1 inhibitor-4) is a HIF-1 inhibitor with IC50 of 560 nM. HIF-1 inhibitor-4 reduces the HIF-1α protein level without affecting its mRNA level.		HIF
T11131	DW14800		Histone Methyltransferase
	DW14800 is an inhibitor of PRMT5 (IC50 = 17 nM), enhances the transcription of HNF4α, and reduces the level of H4R3me2s.		Histone Methyltransferase
T6S1918	Schisantherin B	Gomisin-B,Wuweizi ester-B,Schizantherin-B	Beta Amyloid , Others
	1. Schisantherin B (Schizantherin-B) shows good effect in lowering the serum glutamic-pyruvic transaminase level of the patients suffering from chronic virus hepatitis.		Beta Amyloid , Others
T38173	Propargylcholine	Propargylcholine (bromide)	Antibacterial
	Propargylcholine (Propargylcholine (bromide)) is an alkyne-modified choline analog and inhibits choline catabolism at the level of Dgc enzyme-catalyzed dimethylglycine demethylation in Pseudomonas aeruginosa.		Antibacterial
T25969	Poloxin-2	Poloxin2,Poloxin 2	PLK
	Poloxin-2 is a potent and selective Plk1 PBD inhibitor with anti-tumour activity that reduces the protein level of Plk1 in HeLa cells.		PLK
T21980	PD 198306		MEK
	PD 198306 is a selective inhibitor of MAPK/ERK-kinase (MEK) with antihyperalgesic effects. PD 198306 reduces the Streptozocin-induced increase in the level of active ERK1.		MEK
T3415	Secoisolariciresinol diglucoside	LGM2605	ROS
	Secoisolariciresinol diglucoside (LGM2605) was cytoprotective in an in vitro model of iron overload-induced redox-inflammatory damage. Secoisolariciresinol diglucoside (25 mg/kg b.w.) exerts the antihyperglycemic effect ...		ROS
T39039	FSCPX		Adenosine Receptor
	FSCPX is a potent and selective irreversible antagonist of the A1 adenosine receptor (A1AR), exhibiting low nanomolar binding potency. Additionally, FSCPX can effectively decrease the interstitial adenosine level in the ...		Adenosine Receptor
T0496	Creatinine	NSC13123	Endogenous Metabolite
	Creatinine (NSC-13123) is the breakdown product of creatine, a constituent of muscle tissue, that is excreted by the kidney and whose serum level is used to evaluate kidney function.		Endogenous Metabolite
T32511	L-796,778	L 796,778	Somatostatin
	L-796,778 is an SST3 agonist and a selective ligand of SST3, which can increase the level of cAMP in the body.		Somatostatin
T0254	Probucol	DH-581	Virus Protease , ABC , Lipid
	Probucol (DH-581), an anti-hyperlipidemic drug, can lower the level of cholesterol in the bloodstream by increasing the LDL catabolic rate.		Virus Protease , ABC , Lipid
T5422	CID 1375606	CID-1375606,CID1375606	Others
	CID 1375606 is a surrogate agonist of orphan G protein-coupled receptor GPR27. characterized by a high level of conservation among vertebrates and a predominant expression in the central nervous system.		Others
T20003	Acridone		Antibacterial , ABC
	Acridone could induce cell apoptosis, inhibited ABCG2 (ATP-binding cassette sub-family G member 2) protein, and adjusted hormone level.		Antibacterial , ABC
T1148	Menbutone	Naftobil,Genabilic acid,Genabilin	Others
	Menbutone (Genabilin) is a derivative of oxobutyric acid, and is a choleretic. Menbutone shows a rapid onset of action, reaching its maximum plasma level within 1 hour and lasting for roughly 10 hours.		Others
T20545	Benzarone	Benzarona,Vasoc,Venagil,Benzaronum	OAT
	Benzarone (Benzarona) is a potent inhibitor of human uric acid transporter 1 (URAT1, IC50 = 2.8 μM in oocyte). Benzarone lowers the level of uric acid serum.		OAT
T5735	Methyl deacetylasperulosidate	Deacetyl asperulosidic acid methyl ester,6α-Hydroxygeniposide	Others
	Methyl deacetylasperulosidate (6α-Hydroxygeniposide) is a natual product isolated from the herbs of Hedyotis diffusa Willd,it can lower the blood glucose level in normal mice.		Others