ca-1

Bucladesine sodium (DC2797) is a cAMP analog with cell-permeable properties. Bucladesine sodium is also a cAMP-dependent protein kinase (PKA) activator and a phosphodiester (PDE) inhibitor. Bucladesine sodium has anti-inflammatory activity.

Methocarbamol (AHR 85) is a centrally acting muscle relaxant whose mode of action has not been established. It is used as an adjunct in the symptomatic treatment of musculoskeletal conditions associated with painful muscle spasm.

CA-170 is an orally bioavailable dual inhibitor of VISTA and PD-L1 that selectively restores T-cell proliferation and effector function suppressed by immune checkpoint signaling, while demonstrating minimal off-target activity across a broad receptor and enzyme panel, making CA-170 a valuable compound for immuno-oncology research and immune checkpoint modulation studies.

ICA-105665 (PF-04895162) is a potent and orally active opener of neuronal Kv7.2/7.3 and Kv7.3/7.5 potassium channels. ICA-105665 had low cytotoxic potential in human hepatocytes but inhibited liver mitochondrial function and bile salt export protein (BSEP) transport (IC50 of 311 μM). ICA-105665 can penetrate the central nervous system (CNS) and has antiseizure effects [1][2][3][4].

4,9-dioxatricyclo[5.3.0.0^{3,5}]deca-1(10),7-diene-2,6-diol is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

3-hydroxy-9-methyl-8,17-dioxatricyclo[11.3.1.0^{5,16}]heptadeca-1(16),2,4-triene-7,15-dione is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

15-hydroxy-5,5-dimethyl-4,9-dioxatricyclo[9.4.0.0^{3,8}]pentadeca-1(15),3(8),11,13-tetraene-2,10-dione is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

methyl (10E,12Z)-9-oxooctadeca-10,12-dienoate is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(9Z)-heptadeca-1,9-dien-4,6-diyne-3,8,11-triol is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(10E,12E)-9-hydroxyoctadeca-10,12-dienoic acid is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

9-methoxy-4,4-dimethyl-13-phenyl-6,14-dioxatetracyclo[8.4.0.0^{2,7}.0^{3,5}]tetradeca-1,7,9-trien-11-one is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

15,16-dimethoxytricyclo[12.3.1.1^{2,6}]nonadeca-1(18),2,4,6(19),14,16-hexaene-3,9,17-triol is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(11E,15Z)-9,10,13-trihydroxyoctadeca-11,15-dienoic acid is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(3R,4R,5R)-3-[(11E)-hexadeca-11,15-dien-9-yn-1-yl]-4-hydroxy-5-methyloxolan-2-one is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

7-butyl-10,12-dihydroxy-3,7,9-trimethyl-2,6-dioxatricyclo[7.3.1.0^{5,13}]trideca-1(12),5(13)-diene-4,11-dione is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

15,17-dihydroxy-9-methyl-4,10-dioxatricyclo[11.4.0.0^{3,5}]heptadeca-1(17),13,15-triene-2,11-dione is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

(10Z,13Z)-15,16-dihydroxyoctadeca-10,13-dienoic acid is a high-purity biochemical reagent suitable for biochemical experiments and drug synthesis research.

Deca-1,5,9-triene is a biochemical.

GCA-186 is an effective non-nucleoside HIV-1 reverse transcriptase inhibitor.

KCA-1490 is an inhibitor of dual PDE3/4.

TPCA-1 (TPCA1) is an effective and specific IKK-2 inhibitor (IC50: 17.9 nM); shows >22-fold selectivity over IKK-1 and >550-fold selectivity over others kinases and enzymes.

Deca-1,4,9-triene is a biochemical.

ICA-121431 (2,2-Diphenyl-N-[4-(thiazol-2-ylsulfamoyl) is a nanomolar potent small molecule Nav1.7 channel inhibitor with IC50 of 19 nM for rat Nav1.7, with little or no activity against human Nav1.5 or Nav1.7 channels.

CYCA-117-70, a DCAF1 ligand with a dissociation constant (K D) of 70 μM, serves as an optimal chemical handle for the recruitment of DCAF1 in PROTACs [1].