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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
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Elesclomol
STA-4783
T6170488832-69-5
Elesclomol (STA-4783) is an oxidative stress inducer and a highly lipophilic copper ion carrier. Elesclomol induces apoptosis in tumor cells and is used in copper death related studies. Elesclomol also inhibits FDX1-mediated Fe-S cluster biosynthesis.
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TargetMol | Citations Cited
Escin
Aescin
T02786805-41-0
Escin (Aescin) is biosynthesized from protoaescigenin and barringtogenol, occurring in the seeds of Aesculus.
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Sodium Aescinate
Escin sodium salt
T302720977-05-3
Sodium Aescinate (Escin sodium salt) is extracted from Aesculus wilsonii.
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4-Methylesculetin
4-Methyl-6,7-dihydroxycoumarin, Methylesculetin
TJS0338529-84-0
4-Methylesculetin (Methylesculetin) is one of the coumarin derivatives with great anti-oxidant and anti-inflammatory activities.
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Esculetin
Aesculetin, Cichorigenin
T2798305-01-1
Esculetin (Cichorigenin) is a coumarin derivative from various natural plant products with various biological and pharmaceutical properties including anti-edema, anti-inflammatory and anti-tumour effects. It inhibits lipoxygenases (LOs).
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TargetMol | Citations Cited
Fluorescein diacetate
Di-O-acetylfluorescein, 3,6-Diacetoxyfluoran
T19323596-09-8
Fluorescein diacetate (Di-O-acetylfluorescein) is a cell permeable esterase-substrate for hGSTP1-1.
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Escitalopram Oxalate
Cipralex, (S)-(+)Citalopram oxalate
T6493219861-08-2
Escitalopram Oxalate ((S)-(+)Citalopram oxalate) is a selective serotonin (5-HT) reuptake inhibitor (SSRI) with Ki of 0.89 nM.
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Esculin
Aesculin
T2885531-75-9
Esculin (Aesculin) is a glucoside found in horse chestnuts.
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TargetMol | Citations Cited
Escitalopram
Seroplex, S-(+)-Citalopram, (S)-Citalopram
T0185128196-01-0
Escitalopram (Seroplex) is a furancarbonitrile that is one of the SEROTONIN UPTAKE INHIBITORS used as an antidepressant. The drug is also effective in reducing ethanol uptake in alcoholics and is used in depressed patients who also suffer from tardive dyskinesia in preference to tricyclic antidepressants, which aggravate this condition.
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1-2 weeks
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TargetMol | Citations Cited
Lipopolysaccharides, Escherichiacoli
Lipopolysaccharide, E. coli O111:B4
T4107893572-42-0
Lipopolysaccharides, Escherichiacoli (E. coli O111:B4) are derived from Escherichia coli O111:B4 and are a unique component of the cell wall of Gram-negative bacteria. They are composed of three regions: lipid A, oligosaccharide core, and O-specific polysaccharide (O-antigen). Lipopolysaccharides, Escherichiacoli help maintain the integrity of the cell outer membrane and protect bacteria from bile salts and lipid antibiotics.
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TargetMol | Citations Cited
Desciclovir
BW A515U, 6-Deoxyacyclovir, DCV
T2230484408-37-7
Desciclovir (DCV), a prodrug of the antiherpetic agent acyclovir (ACV), is converted in humans to ACV, presumably by xanthine oxidase.
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TargetMol | Inhibitor Sale
Lushanrubescensin H
T124811
Lushanrubescensin H is a useful organic compound for research related to life sciences and the catalog number is T124811.
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Fluorescein-PEG5-NHS ester
T179442353409-62-6
Fluorescein-PEG5-NHS ester, a PEG-based PROTAC linker, facilitates PROTAC synthesis[1].
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N-(Azido-PEG3)-N-Fluorescein-PEG3-acid
T161912100306-50-9
N-(Azido-PEG3)-N-Fluorescein-PEG3-acid is a PEGylated PROTAC linker with azide, fluorescein, and carboxylic acid functional groups.
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Fluorescein-PEG6-bis-NHS ester
T152952055105-59-2
Fluorescein-PEG6-bis-NHS ester, a polyethylene glycol (PEG)-based linker, is utilized in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
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N-(Azido-PEG2)-N-Fluorescein-PEG3-acid
T161832086689-04-3
N-(Azido-PEG2)-N-Fluorescein-PEG3-acid is a polyethylene glycol (PEG)-derived PROTAC linker designed for PROTAC synthesis[1].
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Rescinnamidine
Reserpic acid
T34291110222-52-1
Rescinnamidine is an alkaloid.
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(±)-H3RESCA-TFP
(±)-H3L28
T195421919794-40-3
(±)-H3RESCA-TFP is a tetrafluorophenyl ester derivative of restrained complexing agent (RESCA).
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6-8 weeks
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Fluorescein-NAD+
T36304
Fluoroscein NAD+ is a substrate for ADP-ribosylation, providing a convenient non-isotopic alternative to radiolabelled NAD for use in PARP assays. Allows direct measurement of NAD-dependent enzymes, such as PARP, by fluorescence microscopy. This product is a replacement for R&D Systems product 4673-500-01 81 μg is supplied as 250 μl of a 0.25 mM solution in water.
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Deacetylescin Ia
TN8086254896-53-2
Deacetylescin Ia (compound 12) is an anti-hyperglycemic deacetylated saponin extracted from de-bittered Ginkgo biloba leaves by deacetylation at position C-22. In mice glucose tolerance tests, Deacetylescin Ia (100mg kg) demonstrated an ability to inhibit the increase in blood sugar levels.
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Rubescensin D
TN826288907-93-1
Rubescensin D is a diterpenoid compound.
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Escin IIB
TN1623158800-83-0
Escin IIB has positive effects on acute inflammation in animals, it can inhibit the induced by serotonin in rats, the hind paw edema induced by carrageenin, and the scratching behavior induced by compound 48 80 in mice.
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N-p-Coumaroyl-N'-caffeoylputrescine
TN60241138156-77-0
N-p-Coumaroyl-N'-caffeoylputrescine is a natural product of Exochorda, Rosaceae. The catalog number is TN6024 and the CAS number is 1138156-77-0. N-p-Coumaroyl-N'-caffeoylputrescine can be used as a reference standard.
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Esculentic acid
TN4013103974-74-9
Esculentic acid has anti-inflammatory effect, it has protective effects against LPS-induced endotoxic shock may be mediated, at least in part, by regulation the release of inflammatory cytokines and mediators, and protein expression of COX-2 in mice.
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