a(2)c

A(2)C is a biochemical.

Anticancer Agent 141 (Compound AE), an antimycin alkaloid, exhibits inhibitory potential against HPV-infected cervical cancer. It impedes HeLa cell proliferation by arresting the cell cycle at the S phase and induces caspase-dependent apoptosis through mitochondrial disruption. This disruption activates the ROS-mediated ubiquitin-dependent proteasome system, leading to the degradation of E6/E7 oncoproteins [1].

c-Fms-IN-2 is an inhibitor of c-FMS kinase (IC50 = 24 nM).

Antifolate C2 (AGF 154) has antitumor activity with an IC of 0.14 nM measured in a growth inhibition assay of human tumor cells.Antifolate C2 can be used for the study of cancer and autoimmune diseases.

NCGC00135472 (DRV1 (GPR32) agonist C2A) is a human Resolvin DI receptor DRV1 agonist with pro-catabolic properties that activates the human soluble protein D1 receptor DRV1/GPR32 receptor in beta-blocker and cAMP assays with EC50s of 0.37 uM and 0.05 uM, respectively.NCGC00135472 induces in cells overexpressing recombinant DRV1 rapid impedance changes that stimulate phagocytosis of serum-treated zymoglycans.

6-fluorinated inated-aristeromycin2c showed antiviral activity against heat virus, Zika virus and Sars coronavirus.

SMN-C2 is a selective regulator of SMN2 gene splicing, a risdiplam analogue, a selective RNA-binding ligand that regulates pre-mRNA splicing and acts by binding to SMN2 pre-mRNA.SMN-C2 has the potential to be used in the study of spinal muscular atrophy (SMA).

N3-PEG3-C2-NHS ester (Azido-PEG3-NHS ester) is an indestructible ADC linker containing 3 PEG units, used to synthesize ADC compounds.

N3-PEG4-C2-NHS ester is a noncleavable, four-unit polyethylene glycol (PEG) linker essential for the synthesis of antibody-drug conjugates (ADCs).

NH2-C6-NH-Boc is a PROTAC linker used in the synthesis of the Mcl-1 inhibitor [based on PROTAC].

2′-C-Methyl-6-O-methylinosine (2′-C-Methyl-6-O-methylinosine) is a hypoxanthine analog exhibiting diverse physical activities for researching various tumor diseases.

Fmoc-NH-PEG12-CH2CH2COOH is a PEG-based PROTAC linker that can be used in PROTAC synthesis.

Mal-PEG2-C2-Boc (Mal-PEG2-T-Butyl Ester) is a PEG-based PROTAC linker. Mal-PEG2-C2-Boc can be used in the synthesis of PROTACs.

Pomalidomide-C2-acid is a PROTAC building block.

PSI-6130 (R 1656) is a potent and selective HCV NS5B polymerase inhibitor. PSI-6130 inhibits HCV replication with a mean IC50 of 0.6 μM.

Thalidomide-O-amido-C3-NH2 TFA (Cereblon Ligand-Linker Conjugates 16 TFA) is a synthesized E3 ligase ligand-linker conjugate incorporating a Thalidomide-based cereblon ligand and a linker used in PROTAC technology.

7H-Pyrrolo[2,3-c]pyridin-7-one,1,6-dihydro-(9CI), with CAS No. 259684-36-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 7H-Pyrrolo[2,3-c]pyridin-7-one,1,6-dihydro-(9CI) provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

5-Chloro-3-iodo-1H-pyrrolo[2,3-c]pyridine, with CAS No. 1190310-51-0, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 5-Chloro-3-iodo-1H-pyrrolo[2,3-c]pyridine provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

c-Kit-IN-2 is a c-KIT inhibitor (IC50: 82 nM) exhibiting superior antiproliferative activities against all three GIST cell lines, GIST430, GIST882, and GIST48 (GI50s: 1, 3, and 2 nM).

c-Met-IN-2 is a selective and orally available c-Met inhibitor (IC50: 0.6 nM) exhibiting antitumor activity.

8-C-(2-Rhamnosyl-6-deoxyhexopyranosulyl)luteolin is a useful organic compound for research related to life sciences. The catalog number is T123914 and the CAS number is 933463-03-7.

Apigenin 6-C-(2-O-feruloyl)glucoside 8-C-glucoside is a useful organic compound for research related to life sciences and the catalog number is T126101.

T338C Src-IN-2 is a potent inhibitor of the mutant c-Src T338C kinase (IC50 of 317 nM), and it also inhibits T338C/V323A and T338C/V323S with IC50 values of 57 nM and 19 nM, respectively.

1-(2'-O-4-C-Methylene-beta-D-ribofuranosyl)thymine is a bicyclic nucleoside.