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Cat No. | Product Name | Synonyms | Targets |
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T11020 | DHODH-IN-11 | Dehydrogenase , DNA/RNA Synthesis | |
DHODH-IN-11 is a leflunomide derivative and weak dihydroorotate dehydrogenase (DHODH) inhibitor with a pKa of 5.03. | |||
T22358 | Etalocib | LY293111,VML295 | Apoptosis , Leukotriene Receptor , LTR |
Etalocib (LY293111) is a novel diaryl ether carboxylic acid derivative, is a selective and potent inhibitor of the lipoxygenase pathway either via antagonism of the leukotriene B4 (LTB4) receptor or directly through 5'-l... | |||
T21606L | Anti-Inflammatory Peptide 1 Acetate | Anti-Inflammatory Peptide 1 Acetate(118850-70-8 Free base) | Phospholipase |
Anti-Inflammatory Peptide 1 Acetate (C45H82N12O14S2) possesses a potent anti-inflammatory activity in vivo and is a strong inhibitor of phospholipase A2 (PLA2), whose increased presence and activity results in inflammati... | |||
T41302 | Itaconate-alkyne | ITalk | Others |
Itaconate-alkyne (ITalk) is a bioorthogonal probe for quantitative and site-specific chemoproteomic profiling of itaconate in inflammatory macrophages and enables biochemical evaluation and proteomic analysis of its dire... | |||
T12856 | SC-26196 | Others | |
SC-26196 is an orally active inhibitor of Delta6 desaturase (D6D) with IC50 of 0.2 µM in a rat liver microsomal assay, with antiinflammatory properties. | |||
T1163 | Betamethasone valerate | Betnovate,Betaderm,Betamethasone 17-valerate,Luxiq | Glucocorticoid Receptor |
Betamethasone valerate (Luxiq) is a synthetic glucocorticoid with metabolic, immunosuppressive and anti-inflammatory actions. | |||
T0383 | Fenspiride hydrochloride | Fenspiride HCl,Pneumorel,Fluiden,Decaspiride | Adrenergic Receptor , PDE , Histamine Receptor |
Fenspiride hydrochloride (Decaspiride) , an oxazolidinone spiro compound, is a drug used in the therapy of certain respiratory diseases. It is approved for use in Russia for the therapy of chronic and acute inflammatory ... | |||
T10091 | Anti-inflammatory agent 1 | Others | |
Anti-inflammatory agent 1 is an anti-inflammatory compound. | |||
T40380 | 17α-Hydroxyprogesterone acetate | Others | |
17α-Hydroxyprogesterone acetate possesses progestational activity. 17α-Hydroxyprogesterone acetate shows antiinflammatory effects at the murine maternal-fetal interface. | |||
T64332 | Glimepiride sulfonamide | Immunology/Inflammation related | |
Glimepiride sulfonamide is an antiinflammatory agent. | |||
T19694 | Hydronidone | F351,F-351,F 351 | Others |
Hydronidone (F-351) is Non-Steroidal Antiinflammatory Drugs. It potentially for the treatment of hepatic fibrosis. | |||
T0270 | Hydrocortisone 17-butyrate | Cortisol 17-butyrate,Hydrocortisone butyrate | Glucocorticoid Receptor , Annexin A , Adrenergic Receptor |
Hydrocortisone 17-butyrate (Cortisol 17-butyrate) is a synthetic glucocorticoid receptor agonist with antiinflammatory, antipruritic and vasoconstrictive effects. | |||
T1586 | Tenoxicam | Ro-12-0068,Tenoxicamum,Mobiflex,Tilcotil | COX |
Tenoxicam (Tilcotil), an antiinflammatory agent with analgesic and antipyretic properties, is used to treat osteoarthritis and control acute pain. | |||
T15126 | Diflumidone | R807 | Others |
Diflumidone, a non-steroidal, is an antiinflammatory drug. | |||
T11196 | Enazadrem | Lipoxygenase | |
Enazadrem is a 5-lipoxygenase inhibitor with antiinflammatory activities. | |||
T12535 | Prednisolone Tebutate | Others | |
Prednisolone Tebutate is a synthetic glucocorticoid, and is an antiinflammatory and immunosuppressant. | |||
T26912 | Broperamole | ||
Broperamole, an antiinflammatory, has been found to help with gastrointestinal microbleeding. | |||
T7710L | Mofebutazone sodium | BRN0213056,BRN 0213056,BRN-0213056 | |
Mofebutazone sodium is, a nonsteroidal antiinflammatory drug (NSAID), is used to treat joint and muscular pain. | |||
T27573 | Ibuproxam | Ibuproxamum,G-277 | |
Ibuproxam, a nonsteroidal antiinflammatory drug (NSAID), is used for the treatment of musculoskeletal pain, arthritis, and soft-tissue disorders. | |||
T12063 | MK-447 | Others | |
MK-447 is a nonsteroidal antiinflammatory agent. | |||
T15774 | Losmiprofen | Others | |
Losmiprofen is a nonsteroidal compound of antiinflammatory. | |||
T11271 | Fenclozine | Others | |
Fenclozine is a non-steroidal antiinflammatory drug. | |||
T27658 | JNJ-10191584 | VUF-6002,JNJ10191584 | |
JNJ-10191584, a potent and selective antagonist at the histamine H4 receptor, has antiinflammatory and analgesic effects in animal studies of acute inflammation. | |||
T68926 | Indomethacin salicylate | ||
Indomethacin salicylate is an antiinflammatory drug. It has shown remarkable inhibitory effects on carrageenin edema, ultraviolet erythema and adjuvant arthritis. | |||
T60816 | Protizinic acid | ||
Protizinic acid inhibits phospholipase A2 (PLA2) with an IC 50 of 210 μM. Protizinic acid has antiinflammatory and antipyretic activity which is an orally active non-steroidal antiinflammatory agent [1] [2]. | |||
T40461 | Ibuprofen alcohol | ||
Ibuprofen alcohol, a nonsteroidal antiinflammatory drug (NSAID), exhibits very little activity for acid-sensing ion channels (ASICs). | |||
T15021 | CV-159 | Others | |
CV-159 is a unique dihydropyridine Ca2+ antagonist with antiinflammatory activities. It has an anti-calmodulin (CaM) action. | |||
T27167 | Diclofenac Acyl Glucuronide | ||
Diclofenac Acyl Glucuronide is a major biliary metabolite of Diclofenac (GLXC-07892), a nonsteroidal antiinflammatory drug and COX inhibitor. | |||
T11998 | Meloxicam-d3 | Meloxicam D4 | Others |
Meloxicam D4 is deuterium labeled Meloxicam. Meloxicam is a non-steroidal antiinflammatory agent, inhibits COX activity,(Target:COX-1; IC50: 36.6 μM ;(Target:COX-2; IC50: 0.49 μM). | |||
T69491 | (E/Z)-Ensifentrine | ||
(E/Z)-Ensifentrine is a potent and selective PDE3/4 inhibitor. (E/Z)-Ensifentrine acts as a long-acting inhibitor of the phosphodiesterase enzymes PDE-3 and PDE-4, producing both bronchodilator and antiinflammatory effec... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
TN1006 | Tirucallol | NOS , NO Synthase , Prostaglandin Receptor | |
Tirucallol is an antiinflammatory agent isolated from Euphorbia lactea.Tirucallol exerts a topical anti-inflammatory effect in vivo, via a mechanism of action related to the neutrophil migration. | |||
TN1712 | Gossypin | NF-κB , S6 Kinase | |
Gossypin has antidiabetic, antioxdiant, anticonvulsant, anti-allergic, antiinflammatory, antinociceptive, cytotoxic and antibacterial activities; it inhibits the NF-kappaB activation pathway, which may explain its role i... | |||
T6S2384 | Poliumoside | Reductase | |
Poliumoside is a natural compound which exhibits significant inhibition of advanced glycation end product formation with IC50 value of 4.6-25.7 μM, it also exhibits great inhibitory effects on rat lens aldose reductase w... | |||
TL0007 | Bisdemethoxycurcumin | Curcumin III,Didemethoxycurcumin | Epigenetic Reader Domain , Wnt/beta-catenin |
Bisdemethoxycurcumin (Curcumin III) is a natural demethoxy derivative of curcumin. It is a potent activator of macrophage phagocytosis, interacting with 1α, 25-dihydroxy vitamin D3 to stimulate amyloid-β clearance by mac... | |||
T3S0153 | Xanthatin | Apoptosis , VEGFR , Lipoxygenase , Wnt/beta-catenin , Antibacterial | |
1. Xanthatin has cytotoxic activity. 2. Xanthatin has antibacterial and antifungal activies against MRSA. 3. Xanthatin may have therapeutic potential against NSCLC. 4. Xanthatin can inhibit murine melanoma B16-F1 cell pr... | |||
T8293 | γ-Tocopherol | (+)-γ-Tocopherol | COX |
(+)-γ-Tocopherol ((+)-γ-Tocopherol) is one of the naturally occurring forms of Vitamin E. It is the most abundant Tocopherol in soybean and corn oils. | |||
T6S1369 | Vitexin | Apigenin-8-C-glucoside | Antioxidant |
1. Vitexin has antinociceptive and antispasmodic activities. 2. Vitexin exhibits a prominent first-pass effect. 3. Vitexin has antioxidant, antimyeloperoxidase, and α-glucosidase inhibitory activities. 4. Vitexin can eit... | |||
TN1563 | Dehydropachymic acid | Autophagy , Immunology/Inflammation related | |
Dehydropachymic acid shows antiinflammatory activity. | |||
T5783 | Rosamultin | Antioxidant , HIV Protease | |
Rosamultin has antioxidant, antiinflammatory/antinociceptive properties,and has anti-human immunodeficiency virus (HIV) activity. | |||
TN1490 | Chrysoeriol | ERK , p38 MAPK , Akt | |
Chrysoeriol has antioxidant, antiinflammatory, antitumor, antimicrobial, antiviral, and free radical scavenging activities, it also shows selective bronchodilator effect. | |||
T3021 | Bulleyaconitine A | Bulleyaconi cine A | Sodium Channel |
Bulleyaconitine A (Bulleyaconi cine A), an analgesic and antiinflammatory drug isolated from Aconitum plants, has several potential targets, such as voltage-gated Na+ channels. | |||
TN1047 | Ingenol mebutate | Ingenol 3-Angelate,PEP005 | gp120/CD4 , HIV Protease , PKC |
Ingenol mebutate (Ingenol 3-Angelate) is a potent activator of PKC subtypes including PKC-α, PKC-β, PKC-γ, PKC-δ, and PKC-ε with Kis of 0.3, 0.105, 0.162, 0.376, and 0.171 nM. Ingenol mebutate exhibits antiinflammatory a... | |||
T6S0627 | Mesaconitine | TNF | |
1. Mesaconitine has antiinflammatory activity. 2. Mesaconitine has antinociceptive activity through cyclic AMP and stimulation of the central β-adrenergic system. | |||
T0492 | Dimethyl fumarate | DMF | Reactive Oxygen Species , HIV Protease , Nrf2 , Endogenous Metabolite , Autophagy |
Dimethyl fumarate (DMF), a fumarate derivative, is used as antiinflammatory and immunomodulatory agent. | |||
TCS0862 | P-Anisic acid | 4-Methoxybenzoic acid,Draconic Acid,4-Anisic Acid | Endogenous Metabolite , Antibacterial |
1. 4-Methoxybenzoic acid could be used as raw material in cosmetic and dermatologic products and/or aroma components in foodstuffs, it has antiinflammatory and antimicrobial activities. | |||
TN4660 | Niranthin | Anti-infection , HBV , PAFR , Topoisomerase | |
Niranthin is a potent anti-leishmanial agent, inhibits the relaxation activity of heterodimeric type IB topoisomerase of L. donovani and acts as a non-competitive inhibitor interacting with both subunits of the enzyme. N... | |||
TN1249 | 3-Epiursolic acid | Cysteine Protease , Immunology/Inflammation related | |
3-Epiursolic acid may have antiinflammatory activity, it shows inhibition on Cathepsins L (catL), the IC50 value of 6.5 μM, cathepsins L (catL) and B play an important role in tumor progression and have been considered p... | |||
T2838 | Naringenin | Naringetol,S-Dihydrogenistein,Pelargidanon,Salipurol,NSC 11855,NSC 34875 | P450 , Influenza Virus , Reactive Oxygen Species , Endogenous Metabolite , PPAR |
Naringenin (NSC-11855) is a flavanone that is considered to have a bioactive effect on human health as antioxidant, free radical scavenger, antiinflammatory, carbohydrate metabolism promoter, immunity system modulater. T... | |||
T2897 | (Rac)-Shikonin | (±)-Shikonin,Alkanet extract,Anchusin,Anchusa acid | Others |
(Rac)-Shikonin (Anchusin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals, cosmetics,... | |||
TN1413 | Atranorin | Endogenous Metabolite , NO Synthase , Ras | |
Atranorin shows significant antinociceptive and antiinflammatory activities, it has a relevant redox-active action, acting as a pro-oxidant or antioxidant agent depending on the radical, also, it will exert cytoprotectiv... | |||
T3836 | Eudesmin | MAPK , S6 Kinase | |
Eudesmin shows antiinflammatory, neuritogenic, anticonvulsant and sedative effects, the mechanism of eudesmin may be related to up-regulation of GABAA and GAD65 expressions, and anti-apoptosis of neuron the in brain.50 m... | |||
TN2080 | Pinoresinol | (+)-Pinoresinol | Apoptosis , NF-κB , CDK , p53 |
Pinoresinol ((+)-Pinoresinol) has antiinflammatory, hepatoprotective, and fungicidal activities, it can protect pial microcirculation from I-reperfusion injury, to increase nitric oxide release and to reduce oxidative st... | |||
T4958 | (-)-Alkannin | Alkannin,Shikonin | Apoptosis , PI3K |
(-)-Alkannin (Shikonin) is a natural red naphthoquinone pigment, has antimicrobial, anti-tumor, and anti-inflammatory effects; a purified shikonin preparation is widely used for the production of medicinals, cosmetics, a... | |||
T4S0145 | Corylifol A | Corylinin | hCE , STAT , UGT |
1. Corylifol A (Corylinin) displays cytotoxic activity against HepG2 and Hep3B hepatocellular carcinoma cell lines, with IC50 values of 4.6 and 13.5 ug/ml, respectively. 2. Corylifol A and Biochanin A can be the potentia... | |||
TN3436 | Ar-Curcumene | Others | |
ar-Curcumene has antiinflammatory activity, it could be used as antiinflammatory drugs in respiratory infections. ar-Curcumene is effective as oviposition deterrents against Anopheles stephensi, Aedes aegypti, and Culex ... | |||
TN2002 | Obovatol | BCL , Caspase , JAK | |
Obovatol has antioxidant, neuroprotective, antiinflammatory, antithrombotic and antitumour effects, it is a potent NF-κB inhibitors for Alzheimer's disease treatment. | |||
T4S1472 | Cucurbitacin S | ||
Cucurbitacins from Wilbrandia ebracteata have analgesic effects. Cucurbitacin S has anticancer and antiinflammatory activities. | |||
TN3620 | Celaphanol A | NF-κB | |
Celaphanol A shows moderate inhibition in both NF-κB activation and nitric oxide production, suggests that it is a possible inhibitor of the NF-kappaB pathway and has antiinflammatory activity. | |||
TN7116 | 6'-Hydroxy-3,4,2',3',4'-pentamethoxychalcone | Others | |
6'-Hydroxy-3,4,2',3',4'-pentamethoxychalcone is an alkenylphenol from Piper obliquum with antiinflammatory and antibacterial activities. | |||
TN3444 | Aristolactam BII | HIV Protease | |
Aristolactam BII exhibits antimicrobial and antiinflammatory activity, it shows significant activity towards DPPH radical scavenging and potent inhibitory effects against tyrosinase mushroom. Aristolactam BII also exerts... | |||
TN1080 | Kaji-ichigoside F1 | ||
Kaji-ichigoside F1 shows antiinflammatory/antinociceptive action in acetic acid-induced writhing and hot plate testing and in a carrageenan-induced paw edema model in mice and rats. Kaji-ichigoside F1 exhibits in vivo he... | |||
TN4648 | Nepetoidin B | IL Receptor , p38 MAPK , TNF , NOS , NF-κB , COX , Antibacterial , JNK , Antifection , Antifungal | |
Nepetoidin B has anti-fungal, anti-bacterial, and antiinflammatory effects, it can inhibit LPS-stimulated NO production possibly via modulation of iNOS mediated by MKP-5/NF-κB pathways in RAW 264.7 cells. |
Cat No. | Product Name | Species | Expression System |
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TMPK-00765 | Pentraxin 2/SAP Protein, Human, Recombinant (hFc) | Human | HEK293 |
Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating level is decreased in chronic human fibrotic recombinant human ... | |||
TMPK-00113 | Pentraxin 2/SAP Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Pentraxin-2 (PTX-2), also known as serum amyloid P component (SAP/APCS), is a constitutive, antiinflammatory, innate immune plasma protein whose circulating level is decreased in chronic human fibrotic recombinant human ... | |||
TMPY-02138 | Uteroglobin Protein, Human, Recombinant (His) | Human | HEK293 |
Uteroglobin (UG), also known as Secretoglobin 1A member 1 (SCGB1A1), Blastokinin, Clara cell secretor protein (CCSP) or Clara cell-specific 10-kDa protein (CC10), is the founding member of the secretoglobin family of sma... | |||
TMPJ-00021 | LGALS1 Protein, Human, Recombinant (His) | Human | E. coli |
Galectin-1 is a member of growing family of evolutionary conserved animal lectins. Galectin-1 is widely expressed in many cells and tissues. Galectins consists of a Galectin domain and two Beta-galactoside binding domain... | |||
TMPY-02328 | Uteroglobin Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Uteroglobin (UG), also known as Secretoglobin 1A member 1 (SCGB1A1), Blastokinin, Clara cell secretor protein (CCSP) or Clara cell-specific 10-kDa protein (CC10), is the founding member of the secretoglobin family of sma... |
Cat No. | Product Name | ||
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L4710 | Nonsteroidal Anti-Inflammatory Compound Library | 530 compounds | |
530 non-steroidal anti-inflammatory compounds for high-throughput and high-content screening. | |||
L6710 | Anti-Inflammatory Traditional Chinese Medicine Compound Library | 1260 compounds | |
A collection of 1260 TCM monomers with anti-inflammatory activity or targeting molecular therapeutic targets in inflammation, a powerful tool for drug discovery and mechanism study; | |||
L6120 | Flavonoid Natural Product Library | 477 compounds | |
A unique collection of 477 flavonoids can be used for high throughput and high content screening; |