b 8

Junipediol B 8-O-glucoside is a phenylpropane extracted from the above-ground parts of Juniperus phoenicea.

Torachrysone-8-O-b-D-glucoside exhibits alpha-glucosidase inhibitory activities and may be utilized for managing type 2 diabetes.

2,2-Dimethyl-6-phenylpyrano[3,4-b]pyran-8-one is a natural product derived from the metabolites of Hypericum revolutum ssp.

Methyl 8-hydroxy-3-(2-methoxy-2-oxoethyl)-6-methyl-9-oxo-9H-furo[3,4-b]chromene-1-carboxylate is a natural product for research related to life sciences. The catalog number is TN4537 and the CAS number is 96287-41-1.

8-Formylophiopogonone B can be isolated from Ophiopogon japonicus.

8-formyl ophiopogonanone B is a natural product that can be used in related research in the field of life sciences. Its product number is TN8529.

Polymyxin B Sulfate (Poly-RX) is a mixture of polymyxins B1 and B2, obtained from Bacillus polymyxa strains. They are basic polypeptides of about eight amino acids and have cationic detergent action on cell membranes. Polymyxin B Sulfate (Poly-RX) is used for infections with gram-negative organisms, but may be neurotoxic and nephrotoxic.

ALOIN Inhibits Interleukin (IL)-1β-Stimulated IL-8 Production in KB Cells.

Amentoflavone (3',8''-Biapigenin), as a potent inhibitor of CYP3A4 and CYP2C9, can interact with many other medications. CYP3A4 and CYP2C9 are proteins used for drug metabolism in the body. Amentoflavone also is an inhibitor of human cathepsin B. It has antimalarial activity in trials significant affinities towards the Delta-1, kappa opioid receptors (as an antagonist) and binds to benzodiazepine receptors. Amentoflavone may be a potential lead for a new type of anti-inflammatory agents having the dual inhibitory activity of group II phospholipase A2 and cyclooxygenase. Amentoflavone and quercetin differentially exerted suppression of PGE2 biosynthesis via downregulation of COX-2 iNOS expression.

1. Swertianolin (Bellidifolin-8-O-Glucoside), mangiferin, rhodenthoside A-C, isoorientin, isovitexin, and amarogentin would serve as potential chemotaxonomic markers to differentiate Gentianaceae species. 2. Swertianolin and swertiamarin show significant hepatoprotective effect in the liver damage model induced by alpha-naphthylisot hiocyanate. 3. Swertianolin shows anti-acetylcholinesterase activity effects. 4. Swertianolin shows that it can scavenge superoxide and hydroxyl radicals with the studying method of the autoxidation of Pyrogallol and afenton.

Cynatratoside B is a useful organic compound for research related to life sciences. The catalog number is T123832 and the CAS number is 97399-97-8.

Uvidin B is a natural product that can be used as a reference standard. The CAS number of Uvidin B is 74636-05-8.

Grayanoside B is a useful organic compound for research related to life sciences. The catalog number is T124361 and the CAS number is 70474-75-8.

1-O-(3,4,5-Trimethoxybenzoyl)-b-D-glucopyranoside is a useful organic compound for research related to life sciences. The catalog number is T124637 and the CAS number is 56982-70-8.

Neoechinulin B is a useful organic compound for research related to life sciences. The catalog number is T124671 and the CAS number is 55179-53-8.

Virolongin B is a useful organic compound for research related to life sciences. The catalog number is T124874 and the CAS number is 41535-94-8.

Yayoisaponin B is a useful organic compound for research related to life sciences. The catalog number is T125328 and the CAS number is 218934-74-8.

Wikstrol B is a natural product that can be used as a reference standard. The CAS number of Wikstrol B is 160963-92-8.

Nelumnucifoside B is a useful organic compound for research related to life sciences. The catalog number is T125864 and the CAS number is 1437780-99-8.

Panowamycin B is a useful organic compound for research related to life sciences. The catalog number is T125968 and the CAS number is 1375224-56-8.

Eleutherazine B is a useful organic compound for research related to life sciences. The catalog number is T126281 and the CAS number is 1175697-97-8.

Terpendole I is a fungal metabolite that has been found in A. yamanashiensis.1 It is a weak inhibitor of acyl-coenzyme A:cholesterol acyltransferase (ACAT; IC50 = 145 μM) and is active against the bacteria B. cereus and B. subtilis (MICs = 100 μg/ml for both) but not S. aureus, P. aeruginosa, or K. pneumoniae (MICs = >200 μg/ml for all) or the fungus C. albicans (MIC = 200 μg/ml).1,2 It is cytotoxic to HeLa cells with an IC50 value of 52.6 μM.3 |1. Tomoda, H., Tabata, N., Yang, D.-J., et al. Terpendoles, novel ACAT inhibitors produced by Albophoma yamanashiensis. III. Production, isolation and structure elucidation of new components. J. Antibiot. (Tokyo) 48(8), 793-804 (1995).|2. Zhao, J.-C., Wang, Y.-L., Zhang, T.-Y., et al. Indole diterpenoids from the endophytic fungus Drechmeria sp. as natural antimicrobial agents. Phytochemistry 148, 21-28 (2018).|3. Nagumo, Y., Motoyama, T., Hayashi, T., et al. Structure-activity relationships of terpendole E and its natural derivatives. ChemistrySelect 2(4), 1533-1536 (2017).

Sphingosine (d14:1) is a bioactive sphingolipid that has been found in B. mori (silkworm), P. clarkii (crayfish), and A. aurita (jellyfish) extracts. It increases the germination rate of N. rileyi, an entomopathogenic fungus, with an EC50 value of 10.2 nM. Sphingosine (d14:1) inhibits protein kinase C (PKC) in vitro (IC50 = 7.3 mol%) as well as superoxide generation induced by phorbol 12-myristate 13-acetate in neutrophils and reduces growth of CHO cells (IC50s = 19 and 8 μM, respectively).

Rhein-8-O-beta-D-glucopyranoside(Rhein-8-glucoside calcium (Rhein-8-glucoside calcium salt) salt) shows moderate bioactivity against human Protein Tyrosine Phosphatase 1B (hPTP1B) in vitro.